ʻO Dubin-Johnson maʻi

ʻO Dubin-Johnson Syndrome (DJS) kahi maʻi i hala i nā ʻohana (hoʻoilina). I kēia kūlana, loaʻa paha iā ʻoe kahi jaundice akahai i ke ola holoʻokoʻa.

ʻO DJS kahi maʻi maʻi ʻōiwi loa. I mea e hoʻoilina ai i ke ʻano, pono i kahi keiki e loaʻa kahi kope o ka ʻāpana hemahema mai nā mākua ʻelua.

Hoʻopilikia ka maʻi maʻi i ka hiki i ke kino ke neʻe i ka bilirubin ma o ke akepaʻa i ka pā. Ke wāwahi ke akepaʻa a me ka pelele i nā hunaola ʻulaʻula, hana ʻia ka bilirubin. Holo maʻamau ʻo Bilirubin i loko o ka pā, i hua ʻia e ke ake. A laila kahe ia i loko o nā aʻa oʻa, hala i ka gallbladder, a i loko o ka ʻōnaehana digestive.

Ke lawe ʻole ʻia ʻo bilirubin i loko o ka bile, kūkulu ia i ke kahe o ke koko. ʻO kēia ke kumu e melemele ai ka ʻili a me nā keʻokeʻo o nā maka. Kapa ʻia kēia ʻo jaundice. Hiki i nā pae kiʻekiʻe ʻo bilirubin ke hōʻino i ka lolo a me nā mea ʻē aʻe.

ʻO ka poʻe me DJS he jaundice mālie i ko lākou ola a hiki ke hōʻeha ʻia e:

• ʻAlekohola
• Pila pale hānau
• ʻO nā kumu kaiapuni e hoʻopili i ke ake
• Maʻi kīnā
• Hapai keiki

ʻO ka jaundice liʻiliʻi, ʻaʻole e hōʻike ʻia a hiki i ka wā ʻōpio a makua paha, ʻo ia wale nō ka hōʻailona o DJS.

Hiki i nā hōʻike aʻe ke kōkua i ke kuhi ʻana i kēia maʻi.

• ʻO ka biopsy ate
• Nā pae enzyme ate (hoʻāʻo ke koko)
• Serum bilirubin
• Nā pae coproporphyrin urinary, me ka pae coproporphyrin I

ʻAʻole koi ʻia kahi lapaʻau kūikawā.

He maikaʻi loa ka nānā aku. ʻAʻole hoʻopōkole ʻo DJS i ke ola o ke kanaka.

Kūpono ʻole nā ​​pilikia, akā hiki ke hoʻopili ʻia i kēia mau mea:

• Abdominal eha
• Jaundice nui loa

Kāhea i kāu mea mālama ola inā loaʻa kekahi o kēia mau mea:

• Kūleʻa ʻo Jaundice
• Hoʻonui ʻo Jaundice i ka hala ʻana o ka manawa
• Loaʻa iā ʻoe ka ʻeha o ka ʻōpū a i ʻole nā ​​hōʻailona ʻē aʻe (kahi hōʻailona paha ia e hōʻeha ʻia kekahi maʻi maʻi ʻē aʻe)

Inā loaʻa iā ʻoe kahi moʻolelo ʻohana o DJS, kōkua paha ka ʻōlelo aʻoaʻo kūpuna inā ʻoe e hoʻolālā e loaʻa nā keiki.

• Nā ʻōnaehana ʻōnaehana Digestive

Korenblat KM, Berk PD. E hoʻokokoke i ka mea maʻi me ka jaundice a i ʻole nā ​​hoʻokolohua ate ʻole. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 138.

Lidofsky SD. ʻO Jaundice. I: Feldman M, Friedman LS, Brandt LJ, eds. ʻO Sleisenger a me Fordtran's Gastrointestinal a me ka maʻi ate. 11th hua. Piladelapia, PA: Elsevier; 2021: chap 21.

Roy-Chowdhury J, Roy-Chowdhury N. Bilirubin metabolism a me kāna mau maʻi. I: Sanyal AJ, Terrault N, huaʻōlelo. ʻO Zakim lāua ʻo Boyer's Hepatology: He puke aʻo no ka maʻi ate. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 58.