ʻO Somatostatinomas

Anter

• Nā ʻōuli o ka somatostatinoma
• Nā kumu a me nā pilikia o somatostatinomas
• Pehea e ʻike ʻia ai kēia mau tumors?
• Pehea lākou e mālama ai?
• Nā kūlana pili a me nā pilikia
• Ka helu ola no somatostatinomas

Hōʻike Overview

ʻO kahi somatostatinoma kahi ʻano laha ʻole o ka tumo neuroendocrine e ulu ana i ka pancreas a i kekahi manawa ka ʻōpū liʻiliʻi. ʻO kahi tumo neuroendocrine kekahi mea i hana ʻia e nā hunaola hana ʻoneoneone. Kāhea ʻia kēia mau hunaola hanaone

Hoʻokumu kikoʻī ʻia kahi somatostatinoma i ka cell delta islet, ʻo ia ke kuleana no ka hana ʻana i ka hormone somatostatin. Hoʻokumu ka tumo i kēia mau pūnaewele e hana i nā mea hou aʻe o kēia hormone.

Ke hana i kou kino i nā hormones somatostatin keu, oki ia i ka hana ʻana i nā hormones pancreatic ʻē aʻe. Ke hiki ʻole i kēlā mau hormones ʻē aʻe, alakaʻi ia i nā ʻōuli e hōʻike ʻia.

Nā ʻōuli o ka somatostatinoma

Hoʻomaka hoʻomaka nā ʻōuli o kahi somatostatinoma i ka palupalu a hoʻonui i ka paʻakikī me ka haʻahaʻa. Kūlike kēia mau ʻōuli me nā mea i hoʻokumu ʻia e nā kūlana olakino ʻē aʻe. No kēia kumu, he mea nui e hana ʻoe i kahi manawa me kāu kauka e loaʻa ai kahi ʻike pololei. Pono kēia e hōʻoia i ka mālama kūpono ʻana no nā ʻano olakino e hōʻike ana i kāu mau ʻōuli.

ʻO nā ʻōuli i hoʻokumu ʻia e ka somatostatinoma e komo pū paha me kēia:

• ʻeha i loko o ka ʻōpū (hōʻailona maʻamau)
• diabetes
• lilo kaumaha maopopo ʻole
• pōhaku ʻalā
• steatorrhea, a i ʻole nā ​​noho momona
• pā paʻa ʻōpū
• pāhoehoe
• jaundice, a i ʻole ʻili melemele (ʻoi aku ka nui inā he somatostatinoma i loko o ka ʻōpū liʻiliʻi)

ʻO nā kūlana olakino ʻē aʻe ma mua o ka somatostatinoma ke kumu nei i kēia mau ʻōuli he nui. ʻO kēia ka hihia pinepine, no ka mea he kakaikahi loa ka somatostatinomas. Eia nō naʻe, ʻo kāu kauka ka mea hiki ke hōʻoia i ke ʻano kikoʻī ma hope o kāu mau hōʻailona kikoʻī.

Nā kumu a me nā pilikia o somatostatinomas

ʻO ke kumu o ka somatostatinoma ʻike ʻole ʻia i kēia manawa. Eia nō naʻe, aia kekahi mau mea pilikia e alakaʻi i kahi somatostatinoma.

ʻO kēia kūlana, hiki ke hoʻopili i nā kāne a me nā wahine, hana maʻamau ma hope o ka makahiki 50. ʻO nā mea aʻe e hiki ai ke hōʻeha i nā neuroendocrine tumors.

• kahi moʻolelo ʻohana o nā endopine neoplasia ʻano 1 (MEN1), kahi ʻano laha ʻole o ka maʻi ʻaʻai i hoʻoilina.
• neurofibromatosis
• ʻO ka maʻi ʻo Hippel-Lindau
• maʻi puʻuwai tuberous

Pehea e ʻike ʻia ai kēia mau tumors?

Pono e hana i kahi hōʻike e kekahi kauka. E hoʻomaka pinepine kāu kauka i ke kaʻina hana diagnost me kahi hoʻokolohua koko wikiwiki. Nānā kēia hōʻike no kahi pae somatostatin kiʻekiʻe. Ukali pinepine ʻia ke hoʻokolohua koko e hoʻokahi a ʻoi paha o kēia mau scan diagnostic a i ʻole nā ​​kukuna X:

• endoscopic ultrasound
• CT scan
• octreoscan (ʻo ia ka scan radioaktif)
• MRI hoʻoili

ʻAe kēia mau hoʻāʻo e ʻike i kāu kauka ka hikoko, a he maʻi ʻaʻai paha ia, a ʻaʻohe noncancerous. ʻO ka hapanui o somatostatinomas he maʻi ʻaʻai. ʻO ke ala wale nō e hoʻoholo ai inā he maʻi ʻaʻai kou tumo me ka ʻoki kino.

Pehea lākou e mālama ai?

Hoʻomaʻapaʻa pinepine ʻia kahi somatostatinoma e ka lawe ʻana i ka tumo ma o ka ʻoki kino ʻana. Inā maʻi ʻaʻai ka tumo a ua pāhola ka maʻi ʻaʻai (kahi ʻano i kapa ʻia he metastasis), ʻaʻole paha he koho ke ʻoki. I ka hihia o ka metastasis, e mālama a mālama kāu kauka i nā ʻōuli a pau e pili ana i ka somatostatinoma.

Nā kūlana pili a me nā pilikia

ʻO kekahi o nā ʻano i pili me somatostatinomas e hoʻopili pū i kēia mau mea:

• von Hippel-Lindau maʻi
• MEN1
• neurofibromatosis ʻano 1
• mimikō mellitus

ʻIke mau ʻia ʻo Somatostatinomas i kahi pae ma hope, kahi hiki ke hoʻopili i nā koho lapaʻau. I kahi pae hope loa, ua metastasized paha nā tumors cancerous. Ma hope o ka metastasis, kaupalena ʻia ka lapaʻau ʻana, no ka mea ʻaʻole maʻamau ke koho ʻana.

Ka helu ola no somatostatinomas

ʻOiai ke ʻano laha ʻole o somatostatinomas, maikaʻi ka nānā aku no ka helu ola 5 mau makahiki. Ke hiki ke hoʻoneʻe ʻia kahi somatostatinoma ma kahi o ka lāʻau. Aia kahi kokoke i ka 100 pakeneka ola i ʻelima mau makahiki ma hope o ka hemo ʻana. ʻO ka helu ola ola ʻelima mau makahiki no ka poʻe i mālama ʻia ma hope o ka metastasized o somatostatinoma he 60 pākēneka.

ʻO ke kī e kiʻi i kahi hōʻailona i ka wā hiki. Inā loaʻa iā ʻoe kekahi o nā ʻōuli o ka somatostatinoma, pono ʻoe e hoʻopaʻa manawa me kāu kauka i ka hiki wawe. Hiki i nā hōʻoia diagnostical ke hoʻoholo i ke kumu kikoʻī o kāu mau ʻōuli.

Inā hoʻoholo kāu kauka he somatostatinoma ʻoe, a laila ma mua o kou hoʻomaka ʻana i ka lāʻau, ʻoi aku ka maikaʻi o kāu wānana.