ʻO Tofacitinib

Anter

• Ma mua o ka lawe ʻana i ka tofacitinib,
• Hoʻokumu paha ʻo Tofacitinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

ʻO ka lawe ʻana i ka tofacitinib e hōʻemi paha i kou hiki ke hakakā i ka maʻi a hoʻonui i ka makaʻu e loaʻa ʻoe i kahi maʻi koʻikoʻi, e like me ka maʻi fungal, bacterial, a me nā maʻi viral i hoʻolaha ʻia i loko o ke kino. Pono e mālama ʻia kēia mau maʻi i ka haukapila a make paha ka make. E haʻi i kāu kauka inā loaʻa pinepine ʻoe i kekahi ʻano maʻi a i ʻole inā manaʻo ʻoe he ʻano maʻi paha kāu i kēia manawa. Hoʻopili kēia i nā maʻi liʻiliʻi (e like me nā ʻoki hāmama a i ʻole nā ​​ʻeha), nā maʻi i hiki a hele (e like me nā ʻeha anu), a me nā maʻi maʻi ʻole e hele. E haʻi pū aku i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi diabetes, ka maʻi hoʻomaʻemaʻe kanaka (HIV), loaʻa i ka maʻi maʻi (AIDS), kahi maʻi a me nā ʻano ʻē aʻe e hoʻopili i kāu ʻōnaehana pale Pono ʻoe e haʻi i kāu kauka inā ʻoe e noho a i ʻole i noho ma nā wahi e like me nā awāwa ʻo Ohio a me Misisipi paha kahi e ʻike pinepine ʻia ai nā maʻi fungal. E noi i kāu kauka inā ʻaʻole ʻoe e maopopo inā pili kēia mau maʻi i kou wahi. E haʻi i kāu kauka inā lawe ʻoe i nā lāʻau e hōʻemi i ka hana o ka ʻōnaehana pale pale e like me kēia: abatacept (Orencia); adalimumab (Humira); anakinra (Kineret); azathioprine (Azasan, Imuran); certolizumab (Cimzia); cyclosporine (Gengraf, Neoral, Sandimmune); etanercept (Enbrel); golimumab (Simponi); infliximab (Remicade); methotrexate (Otrexup, Rasuvo, Trexall); rituximab (Rituxan); steroid pū me dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), a me prednisone (Rayos); tacrolimus (Astagraf, Envarsus XR, Prograf); a me tocilizumab (Actemra).

E nānā ana kāu kauka iā ʻoe no nā hōʻailona o ka maʻi i ka wā a ma hope o kāu hoʻoponopono ʻana. Inā loaʻa iā ʻoe kekahi o nā ʻōuli aʻe ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau a i ʻole inā ʻike ʻoe i kekahi o nā ʻōuli ma hope a i ʻole ma hope koke paha o kāu lapaʻau ʻana, e kāhea koke i kāu kauka: fever; kāhili; haʻalulu; ʻeha ka ʻili; ʻeha a paʻakikī paha i ka ale ʻana; uā; pokole o ka hanu; Kaumaha emi; mahana, ʻulaʻula, a ʻeha ʻeha paha; ʻāwīwī ʻeha; ʻeha poʻo, ʻike i ka mālamalama, ʻāʻī ʻoʻoleʻa, huikau; pinepine, ʻeha, a wela paha ka manaʻo i ka wā o ka urination; ʻeha ka ʻōpū; pāhoehoe; aiʻole ka luhi nui loa.

Ua hele a maʻi paha ʻoe i ka maʻi palupalu (TB; kahi maʻi puʻuwai koʻikoʻi) akā ʻaʻole i loaʻa nā ʻōuli o ka maʻi. I kēia hihia, hiki i ka hoʻohana ʻana i ka tofacitinib ke ʻoi aku ke koʻikoʻi i kou maʻi a hoʻoulu iā ʻoe i nā ʻōuli. E hana ana kāu kauka i kahi hoʻāʻo ʻili e ʻike inā loaʻa iā ʻoe kahi maʻi TB hemahema ma mua o kou hoʻomaka ʻana i kāu lāʻau me tofacitinib. Inā pono, e hāʻawi aku kāu kauka iā ʻoe i ka lāʻau e mālama ai i kēia maʻi ma mua o kou hoʻomaka ʻana e hoʻohana iā tofacitinib. E haʻi i kāu kauka inā loaʻa paha iā ʻoe ka TB, inā ua noho ʻoe a kipa paha i kahi ʻāina e maʻa mau ai ka TB, a inā ua puni ʻoe i kekahi me ka TB. Inā loaʻa iā ʻoe kekahi o nā ʻōuli o TB, a i ʻole inā hoʻomōhala ʻoe i kekahi o kēia mau ʻōuli i kou wā e lapaʻau ai, e kāhea koke aku i kāu kauka: batukū, ʻūʻē ʻana i nā aʻa koko, ka pohō kaumaha, ka nalowale ʻana o ke kani o nā mākala, a me ke kuni.

Lawe i ka tofacitinib i ʻoi aku ka nui ma mua o nā kaola i koi ʻia e kumu i nā pilikia puʻuwai koʻikoʻi a hoʻoweliweli paha i ka wā o kāu lapaʻau. E haʻi i kāu kauka inā 50 kou mau makahiki a ʻoi paha a i ʻole inā puhi ʻoe, a inā he kolesterol kiʻekiʻe ʻoe, ke koko kiʻekiʻe, a diabetes paha. Lawe iā tofacitinib e like me ke kuhikuhi. Mai lawe i nā mea hou aʻe a lawe pinepine paha ma mua o ka mea i kauoha ʻia e kāu kauka.

Lawe ka tofacitinib i mea e hoʻonui ai i ka makaʻu e hoʻomohala ʻoe i kahi lymphoma (maʻi ʻaʻai e hoʻomaka i nā hunaola koko e hakakā ai i ka maʻi maʻi) a i ʻole nā ​​ʻano ʻē aʻe, e like me ka maʻi ʻaʻai ʻili. ʻO kekahi poʻe i lawe i ka tofacitinib me nā lāʻau ʻē aʻe ma hope o ka loaʻa ʻana o kahi transplan kidney i hoʻomohala i kahi ʻano i hana i ko lākou kino e hana i nā kino koko keʻokeʻo he nui. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kekahi ʻano maʻi ʻaʻai a i ʻole loaʻa kahi transplant kidney.

Lawe i ka tofacitinib i ka ʻoi aku ka nui ma mua o nā kaola i koi ʻia e hoʻonui ai i ka makaʻu o nā clots koko hoʻoweliweli ola. E haʻi i kāu kauka inā he 50 kou mau makahiki a ʻoi paha a ke makaʻu ʻoe i ka maʻi o ka puʻuwai a i ʻole ke koko. Eia kekahi, e haʻi aku i kāu kauka inā ua loaʻa ʻoe i ke koko i kou mau wāwae, nā lima, a i ʻole nā ​​akemāmā, a i ʻole nā ​​ʻaʻa. Lawe iā tofacitinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka. Inā ʻoe e ʻike i kekahi o nā ʻōuli e pau nei i ka lawe ʻana i ka tofacitinib a kāhea koke aku i kāu kauka: ka hanu ʻana o ka hanu a paʻakikī paha i ka hanu ʻana, ʻeha ka umauma, pehu ka wāwae a lima paha, ʻeha ka wāwae, ʻulaʻula, hoʻoliʻiliʻi, a mehana hoʻi i nā wāwae a me nā lima. .

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me tofacitinib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana hoʻokahi ʻia ʻo Tofacitinib a i ʻole me nā lāʻau ʻē aʻe e mālama ai i ka rheumatoid arthritis (ke ʻano e hoʻouka ai ke kino i kāna mau hui ponoʻī e hōʻeha ai i ka ʻeha, ka pehu ʻana, a me ka nalo ʻana o ka hana) i ka poʻe i pane ʻole i ka methotrexate (Otrexup, Rasuvo, Trexall). Hoʻohana pū ʻia ia me ka methotrexate, sulfasalazine (Azulfidine), a i ʻole leflunomide (Arava) e mālama ai i ka psoriatic arthritis (kahi ʻano e ʻeha ai ka ʻeha pū a me ka pehu ʻana a me nā unahi ma ka ʻili) i ka poʻe i pane ʻole i kēia mau lāʻau. Hoʻohana ʻia ʻo Tofacitinib e mālama i nā kolitis ulcerative (kahi ʻano e hoʻoulu ai a me nā ʻeha i ka uhi o ke kolona [ʻōpū nui] a me ke kīpaha) i ka poʻe hiki ʻole ke lawe a i ʻole i pane ʻole i nā lāʻau hōʻemi tumor tumzrosis factor (TNF). Hoʻohana ʻia ia e mālama i ka polarticular juvenile idiopathic arthritis (PJIA; kahi ʻano o ke kuamoʻo kamaliʻi e pili ana i ʻelima a ʻoi hui pū i loko o nā mahina ʻeono mua o ke ʻano, e ʻeha ai ka pehu, a me ka nalowale ʻana o ka hana) i nā keiki 2 makahiki a ʻoi paha. Aia ʻo Tofacitinib i kahi papa o nā lāʻau i kapa ʻia ʻo Janus kinase (JAK) mea kāohi. Hana ia ma ka hoʻemi ʻana i ka hana o ka ʻōnaehana pale.

Hele mai ʻo Tofacitinib ma ke ʻano he papa, kahi papa hoʻokuʻu lōʻihi (hana lōʻihi), a ma ke ʻano he hopena waha (wai) e lawe ma ka waha. No ka hoʻomaʻamaʻa ʻana i ka colitis ulcerative, rheumatoid arthritis, a i ʻole psoriatic arthritis, lawe pinepine ʻia ka pālua i kēlā me kēia lā me ka ʻole o ka meaʻai a lawe pinepine ʻia ka papa hoʻolōʻihi hoʻolōʻihi ʻia i kēlā me kēia lā me ka ʻai ʻole. No ka hoʻomaʻamaʻa ʻana i ka polarticular course juvenile idiopathic arthritis, lawe pinepine ʻia ka papaha a i ʻole ka hopena waha i ʻelua mau lā me ka ʻai ʻole Lawe iā tofacitinib ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe iā tofacitinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa hoʻolōʻihi lōʻihi; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

E hoʻohana mau i ka syringe dosing waha e hele mai me ka hopena tofacitinib e ana i kāu lāʻau. E kamaʻilio me kāu kauka a kauka paha inā he nīnau kāu e pili ana i ke ana ʻana i kāu hopena o ka hopena tofacitinib.

Inā ʻoe a ʻo kāu keiki paha e lawe nei i ka hopena waha tofacitinib, e noi i kāu kauka lāʻau a i ʻole kauka no kahi kope o nā ʻōlelo a ka mea hana no ka hoʻohana. E heluhelu pono i kēia mau ʻōlelo aʻo.

Pono paha kāu kauka e hōʻemi i kāu lāʻau a i ʻole hoʻokū i kāu lāʻau inā ʻike ʻoe i kekahi hopena ʻino loa. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka tofacitinib,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka tofacitinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā papa tofacitinib, nā papa hoʻokuʻu hoʻokuʻu ʻia, a me nā hopena waha. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono i nā lāʻau i helu ʻia i ka ʻĀINA WAIWAI koʻikoʻi a me kekahi o nā mea aʻe: kekahi mau lāʻau antifungal e like me fluconazole (Diflucan), itraconazole (Onmel, Sporanox), a me ketoconazole; aspirin a me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ibuprofen (Advil, Motrin) a me naproxen (Naprosyn, Aleve); carbamazepine (Carbatrol, Tegretol, Equetro, nā mea ʻē aʻe); clarithromycin (Biaxin, i Prevpac); kekahi mau lāʻau no ka HIV me indinavir (Crixivan), nelfinavir (Viracept), a me ritonavir (Norvir, ma Kaletra); nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); a me rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa iā ʻoe ka ʻeha o ka ʻōpū ʻaʻole i hōʻike ʻia a inā loaʻa a loaʻa paha iā ʻoe nā ulcer (ʻeha i ka uhi ʻana o kou ʻōpū a i ʻole ʻōpū), diverticulitis (ʻōhū o ka pale o ka ʻōpū nui), nā maʻi ate me ka maʻi hepitis ʻO B a i ʻole hepatitis C, maʻi ʻaʻai, anemia (kahi haʻahaʻa ma mua o ka helu maʻamau o nā hunaola ʻulaʻula), dialysis (lapaʻau lapaʻau e hoʻomaʻemaʻe i ke koko ke hana ʻole nā ​​puʻupaʻa), a i ʻole nā ​​maʻi puʻupaʻa. Inā ʻoe e lawe nei i nā papa hoʻokuʻu lōʻihi, e haʻi aku i kāu kauka inā he ʻiki a poloka paha kāu o kāu ʻōnaehana digestive.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. ʻAʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ka tofacitinib. Inā hāpai ʻoe i ka lawe ʻana i ka tofacitinib, e kāhea i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai waiu ʻoiai ʻoe e lawe nei i nā papa tofacitinib a i ʻole ka hopena waha a no ka liʻiliʻi he 18 mau hola ma hope o ka hopena hope loa o ka papaha a i ʻole 36 mau hola ma hope o ka hopena hope loa o ka papa hoʻokuʻu hoʻokuʻu.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ʻia ka momona i nā wahine. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i ka tofacitinib.
• e haʻi i kāu kauka inā loaʻa iā ʻoe i kēia manawa a i ʻole e hoʻolālā ʻia e loaʻa nā lāʻau āpau. Inā makemake ʻoe i nā lāʻau āpau, pono ʻoe e loaʻa nā lāʻau āpau a laila kali i kahi manawa ma mua o ka hoʻomaka ʻana i kāu lāʻau me tofacitinib. ʻAʻohe o nā lāʻau lapaʻau i ka wā o kāu mālama ʻana me ke kamaʻilio ʻole ʻana me kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Tofacitinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• ʻeha poʻo
• ihu peʻa a holo paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• hives, pehu o ka maka, maka, lehelehe, a puʻu paha, paʻakikī i ka ale ʻana a me ka hanu ʻana
• ʻeha o ka ʻōpū, ke hele pū me ke kuni a me ka diarrhea a me ka constipation
• melemele o ka ʻili a me nā maka
• nalo ʻai ʻole
• mimi ʻeleʻele
• neʻe ʻana o ka ʻōpū o ka ʻōpala
• ka luaʻi
• hūwī
• ʻili mae
• pokole o ka hanu

Hiki i ka Tofacitinib ke hoʻonui i kāu pae kolesterol. E kauoha kāu kauka i nā hoʻokolohua e nānā i kāu pae kolesterol i kāu mālama ʻana me tofacitinib. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Tofacitinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. E hoʻolei i nā hopena i hoʻohana ʻole ʻia 60 mau lā ma hope o ka wehe ʻana o ka ʻōmole.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab a ma mua a i kāu wā e mālama ai e nānā i ka pane o kou kino iā tofacitinib.

Inā ʻoe e lawe i nā papa hoʻolōʻihi lōʻihi hiki iā ʻoe ke ʻike i kahi mea e like me ka papa i kāu neʻe ʻana o kou ʻōpū. ʻO kēia wale nō ka pūpū papa hakahaka, a ʻaʻole ia he manaʻo ʻaʻole i loaʻa iā ʻoe ka piha o ka lāʻau.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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