ʻO ka injection Eculizumab

Anter

• Ma mua o ka loaʻa ʻana o ka injection eculizumab,
• Hoʻokumu paha ka injection Eculizumab i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

ʻO ka loaʻa ʻana o ka injection eculizumab e hoʻonui paha i ka makaʻu e hoʻomōhala ʻoe i kahi maʻi meningococcal (kahi maʻi i hiki ke hoʻopili i ka uhi ʻana o ka lolo a me ka iwi kuamoʻo a / a i ʻole hoʻolaha paha ma o ke kahe o ke koko) i kāu mālama ʻana a i kekahi manawa paha ma hope. Hiki i nā maʻi Meningococcal ke make i loko o kahi manawa pōkole. Pono ʻoe e loaʻa i kahi lāʻau koʻokoʻo meningococcal ma ka liʻiliʻi he 2 mau pule ma mua o kou hoʻomaka ʻana i kāu lāʻau me ka pahu ʻana o eculizumab e hoʻemi i ka makaʻu āu e hoʻomōhala ai i kēia ʻano maʻi. Inā ua loaʻa iā ʻoe kēia lāʻau lapaʻau i ka wā ma mua, pono paha ʻoe e loaʻa i kahi lāʻau booster ma mua o kou hoʻomaka ʻana i kāu lāʻau. Inā manaʻo kāu kauka pono ʻoe e hoʻomaka i ka hoʻoponopono ʻana me ka hoʻopili ʻana o eculizumab i kēia manawa, e loaʻa koke iā ʻoe kāu lāʻau lapaʻau meningococcal.

ʻOiai inā loaʻa iā ʻoe ka lāʻau koʻokoʻo meningococcal, aia nō kahi makaʻu e hoʻomohala ʻoe i ka maʻi meningococcal i ka wā a ma hope paha o kāu lapaʻau ʻana me ka injection eculizumab. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka a i ʻole e loaʻa i ke kōkua olakino pōpilikia: ʻeha ke poʻo e hele pū me ka nausea a i ʻole ka luaʻi, ke kuni, kahi ʻāʻī ʻoʻoleʻa, a me kahi kua ʻoʻoleʻa. ke kuni o 103 ° F (39.4 ° C) a ʻoi aku paha; hū a me ka wela; huikau; ʻeha nā mākala a me nā hōʻailona like like me ka flu; aiʻole inā pili kou mau maka i ka mālam.

E haʻi i kāu kauka inā he kuni kou a i ʻole nā ​​hōʻailona ʻino ʻē aʻe ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau me ka injection eculizumab. ʻAʻole hāʻawi kāu kauka iā ʻoe i ka injection eculizumab inā loaʻa i kahi maʻi maʻi meningococcal.

E hāʻawi aku kāu kauka iā ʻoe i kahi kāleka palekana ahonui me ka ʻikepili e pili ana i ka makaʻu o ka ulu ʻana i ka maʻi meningococcal i loko a i ʻole no kekahi manawa ma hope o kāu lapaʻau ʻana. Lawe i kēia kāleka me ʻoe i nā manawa āpau i kāu mālama ʻana a no 3 mau mahina ma hope o kāu lapaʻau. Hōʻike i ke kāleka i nā lawelawe mālama ola āpau nāna e mālama iā ʻoe i ʻike lākou e pili ana i kāu pilikia.

Ua hoʻonohonoho ʻia kahi papahana i kapa ʻia ʻo Soliris REMS e hoʻemi i nā makaʻu o ka loaʻa ʻana o ka eculizumab injection. Hiki iā ʻoe ke loaʻa wale i ka injection eculizumab mai ke kauka i komo i kēia papahana, ua kamaʻilio pū me ʻoe e pili ana i nā pilikia o ka maʻi meningococcal, hāʻawi iā ʻoe i kahi kāleka palekana hoʻomanawanui, a ua hōʻoia ua loaʻa iā ʻoe kahi lāʻau lapaʻau meningococcal.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Kuhi) ke hoʻomaka ʻoe i ka lāʻau me ka ʻekulula eculizumab a i kēlā me kēia manawa ke loaʻa ʻoe i ka ʻume. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana o ka eculizumab injection.

Hoʻohana ʻia ka injection Eculizumab e mālama i ka paroxysmal nocturnal hemoglobinuria (PNH: kahi ʻano anemia kahi i haki ʻia ai nā hunaola ʻulaʻula i loko o ke kino, no laila ʻaʻole lawa nā pūnaewele olakino e lawe i ka oxygen i nā ʻāpana āpau o ke kino). Hoʻohana ʻia ka injection Eculizumab e mālama i ka atypical hemolytic uremic syndrome (aHUS; kahi ʻano hoʻoilina kahi e loaʻa ai ke koko liʻiliʻi i loko o ke kino a e hōʻino paha i nā kīʻaha koko, nā huna koko, nā puʻupaʻa, a me nā ʻāpana ʻē aʻe o ke kino). Hoʻohana pū ʻia ʻo Eculizumab injection e mālama i kekahi ʻano o ka myasthenia gravis (MG; kahi maʻi o ka ʻōnaehana hopohopo e hoʻonāwaliwali i nā mākala). Hoʻohana ʻia ia e mālama i ka maʻi neuromyelitis optica spectrum (NMOSD; kahi maʻi autoimmune o ka ʻōnaehana hopohopo e pili ana i nā aʻa maka a me ka iwi kuamoʻo) i kekahi mau mākua. ʻO ka injection Eculizumab i loko o kahi hui o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ke kāpae ʻana i ka hana o ka ʻāpana o ka ʻōnaehana pale e hōʻino ai i nā hunaola o ke koko i nā poʻe me PNH a ke kumu e hana i nā clots i nā kānaka me aHUS. Hana pū ʻia ia ma ke kāpae ʻana i ka hana o ka ʻāpana o ka ʻōnaehana paleʻea e hōʻino paha i kekahi mau ʻāpana o ke kikowaena pūnaewele i nā poʻe me NMOSD a i ʻole e keakea ʻana i ka kamaʻilio ma waena o nā ʻalalā a me nā mākala i ka poʻe me MG.

Hele mai ka injection Eculizumab ma ke ʻano he hopena (wai) e ʻoki ʻiʻo ʻia (i loko o ke aa) ma kahi o 35 mau minuke e ke kauka a kahu hānai paha i kahi keʻena lapaʻau. Hāʻawi pinepine ʻia i nā mākua i hoʻokahi manawa i ka pule no 5 mau pule a laila hoʻokahi i kēlā me kēia pule. Hiki i nā keiki ke loaʻa i ka eculizumab injection ma kahi papa manawa ʻokoʻa, kaukaʻi ʻia i ko lākou mau makahiki a me ke kaumaha o ke kino. Hāʻawi ʻia kekahi mau kaomi keu o ka hoʻopili ʻana eculizumab ma mua a ma hope paha o kekahi mau ʻano lāʻau e ae no PNH, aHUS, MG, a i ʻole NMOSD.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o ka eculizumab injection a hoʻonui i kāu lāʻau ma hope o 4 mau pule.

Hiki i ka injection Eculizumab ke kumu i nā hopena maʻi kūpilikiʻi. E nānā pono kāu kauka iā ʻoe ke loaʻa iā ʻoe ka lāʻau eculizumab a no 1 hola ma hope o kou loaʻa ʻana i ka lāʻau. Lohi paha kāu kauka i kāu infusion inā loaʻa ʻoe i kahi hopena maʻi ʻaʻa. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e haʻi koke i kāu kauka: ʻeha o ka umauma; nawaliwali ka manaʻo; ʻehu; hives; pehu o nā maka, maka, lehelehe, alelo, a puʻu paha; hoarseness; a i ʻole paʻakikī i ka hanu ʻana a i ʻole ka ale ʻana.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection eculizumab,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka hoʻopili ʻana o eculizumab, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i ka injection eculizumab. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole kekahi maʻi olakino ʻē aʻe.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka loaʻa ʻana o ka injection eculizumab, kāhea i kāu kauka.
• inā e mālama ʻia kāu keiki me ka pahu ʻana o eculizumab, pono e kanikau kāu keiki iā Streptococcus pneumoniae a me Haemophilus influenza type b (Hib) ma mua o ka hoʻomaka ʻana o ka lāʻau. E kamaʻilio me kāu kauka o kāu keiki e pili ana i ka hāʻawi ʻana i kāu keiki i kēia mau lāʻau āpau a me nā lāʻau āpau ʻē aʻe e pono ai kāu keiki.
• inā mālama ʻia ʻoe no PNH, pono ʻoe e ʻike he kumu paha kāu maʻi e hōʻemi ai i nā hunaola ʻulaʻula nui ma hope o kou pau ʻana o ka loaʻa ʻana o ka eculizumab injection. E nānā pono kāu kauka iā ʻoe a kauoha paha i nā hoʻokolohua hale hana i nā pule he 8 ma hope o kou hoʻopau ʻana i kāu lāʻau. Kāhea koke i kāu kauka inā hoʻomohala ʻoe i kekahi o nā ʻōuli penei: huikau, ʻeha o ka umauma, paʻakikī ka hanu ʻana, a i ʻole nā ​​hōʻailona ʻē aʻe ʻē aʻe.
• inā mālama ʻia ʻoe no aHUS, pono ʻoe e ʻike he kumu paha kāu maʻi e hoʻokumu i nā clots koko i kou kino ma hope o kou pau ʻana o ka loaʻa ʻana o ka eculizumab injection. E nānā pono kāu kauka iā ʻoe a kauoha paha i nā hoʻokolohua hale hana i nā hebedoma he 12 ma hope o kou hoʻopau ʻana i kāu lāʻau. Kāhea koke i kāu kauka inā hoʻomohala ʻoe i kekahi o nā ʻōuli penei: pilikia i ka wā e kamaʻilio a hoʻomaopopo paha i ka ʻōlelo; huikau; ka nāwaliwali koke a i ʻole ka helu ʻana o ka lima a me ka wāwae (ʻoi loa ma kekahi ʻaoʻao o ke kino) a i ʻole ke alo; ka pilikia hele wawae, hoʻoluhi, nalo o ke kaulike a i ʻole ka hoʻohui ʻana; maule ana; ka hopu ʻana; ʻeha ka umauma; paʻakikī i ka hanu ʻana; pehu i nā lima a i ʻole nā ​​wāwae; a i ʻole nā ​​ʻōuli ʻē aʻe.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ʻoe e nalo i kahi manawa e loaʻa ai kahi lāʻau o eculizumab injection, e kelepona koke i kāu kauka.

Hoʻokumu paha ka injection Eculizumab i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha poʻo
• ihu ihope
• ʻeha a pehu paha i ka ihu a i ʻole ka puʻu
• ʻūhā
• paʻakikī e hiamoe a hiamoe paha
• luhi nui loa
• ʻūpā
• ʻehaʻeha a ʻeha pū paha
• ʻeha kua
• ʻeha ma nā lima a me nā wāwae
• ʻeha ma ka waha
• pāhoehoe
• nausea
• ka luaʻi
• ʻeha ka ʻōpū
• ʻinoʻī paʻakikī a paʻakikī paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

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• nāwaliwali
• ʻili mae
• pokole o ka hanu

Hoʻokumu paha ka injection Eculizumab i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka eculizumab injection.

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka eculizumab injection.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Soliris^®