Mea Kākau: Gregory Harris
Lā O Ka Hana: 12 Apelila 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
ASCO: Newer Drugs No Better Than Paclitaxel
Wikiō: ASCO: Newer Drugs No Better Than Paclitaxel

Anter

E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate. E kauoha kāu kauka i nā hoʻokolohua hale ʻike e ʻike i ke ʻano o ka maikaʻi o ka hana o kou ake ma mua a i kāu mālama Inā hōʻike nā hoʻokolohua he pilikia kou i ke ake, ʻaʻole paha e hāʻawi kāu kauka iā ʻoe i ka injection a me ka capecitabine (Xeloda). ʻO ka hoʻomaʻamaʻa ʻana me nā ʻoki ʻelua o ka ixabepilone a me ka capecitabine e hana i nā hopena ʻino a make paha i ka poʻe i loaʻa i ka maʻi ate.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana o ka injection.

Hoʻohana wale ʻia ka injection Ixabepilone a i ʻole hui pū ʻia me capecitabine e mālama ai i ka maʻi ʻaʻai umauma i hiki ʻole ke mālama ʻia me nā lāʻau ʻē aʻe. Aia ʻo Ixabepilone i loko o ka papa o nā lāʻau i kapa ʻia nā mea kūpale microtubule. Hana ia ma ka luku ʻana i nā hunaola maʻi ʻaʻai.

ʻO ka injection Ixabepilone e hele mai me he pauka e hoʻohui ʻia i ka wai a injected ma luna o 3 mau hola i loko o ke aniani (i loko o ke aa) e ke kauka a kahu hānai paha. Hoʻokomo pinepine ʻia ia i kēlā me kēia pule i kēlā me kēia 3 pule.

Pono paha kāu kauka e hoʻolohi i kāu lāʻau a hoʻoponopono i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E hāʻawi aku kāu kauka iā ʻoe i nā lāʻau ʻē aʻe e pale a mālama i kekahi mau hopena ʻaoʻao e pili ana i hoʻokahi hola ma mua o kou loaʻa ʻana i kēlā me kēia kaho o ka hoʻopili ʻana iā ixabepilone. E pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ʻia ai me ka injection o ka ixabepilone.


E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka hoʻopili ʻana o ixabepilone,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka ixabepilone, nā lāʻau ʻē aʻe, Cremophor EL (aila castor polyoxyethylated), a i ʻole nā ​​lāʻau i loaʻa iā Cremophor EL e like me paclitaxel (Taxol). E noi i kāu kauka a kauka paha inā ʻaʻole ʻoe e ʻike inā he lāʻau āu e maʻi ai i loko o Cremophor EL.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei, i lawe ʻia nei, a i ʻole hoʻolālā e lawe. E kuhikuhi pono i kekahi o kēia mau mea: kekahi antibiotics e like me clarithromycin (Biaxin) a me telithromycin (Ketek); kekahi mau antifungals e like me itraconazole (Sporanox), ketoconazole (Nizoral), a me voriconazole (Vfend); delavirdine (Mea kākau); dexamethasone (Decadron, Dexpak); erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin); fluconazole (Diflucan); kekahi mau lāʻau no ka hopu ʻana e like me carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal), a me phenytoin (Dilantin, Phenytek); nefazodone; hoʻohana ʻia nā mea hoʻohiwahiwa protease e mālama i nā maʻi maʻi (HIV) e like me amprenavir (Agenerase), atazanavir (Reyataz), indinavir (Crixivan), ritonavir (Norvir, ma Kaletra), nelfinavir (Viracept), a me saquinavir (Invirase); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate a me Rifater); a me ka verapamil (Calan, Covera, Isoptin, Verelan, ma Tarka). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
  • e haʻi i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa ka maʻi diabetes; nā kūlana e hōʻemi i ka helu, puhi a ʻūlū ʻana paha i kou mau lima a me kou mau wāwae; aiʻole maʻi puʻuwai.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. ʻAʻole pono ʻoe e hāpai i ka wā e loaʻa ana iā ʻoe ka iini o ka ixabepilone. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka loaʻa ʻana o ka inikopiko ixabepilone, e kāhea i kāu kauka. Hoʻopilikia paha ka ʻōlani Ixabepilone i ka fetus.
  • pono ʻoe e ʻike i ka ʻāpiki i loko o ka wai ʻona ʻo ixabepilone a hiki ke hiamoe. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe. E kamaʻilio me kāu kauka e pili ana i ka hoʻohana palekana o nā inu wai ʻona a i ʻole nā ​​lāʻau e hiki ai ke hoʻopili i kou noʻonoʻo a hoʻokolokolo paha i ka wā o kāu mālama ʻana me ka inikopiko ixabepilone.

Mai inu i ka wai kawa i ka loaʻa ʻana o kēia lāʻau.


Hoʻokomo paha ka hopena ʻo Ixabepilone i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻeha poʻo
  • poho lauoho
  • ʻili flaky a ʻeleʻele hoʻi
  • nā pilikia me nā manamana wāwae a i ʻole nā ​​manamana lima
  • palupalu, ʻulaʻula nā pāma a me nā kapuwaʻi
  • ʻeha ma ka lehelehe a i ka waha a i ʻole ka puʻu
  • pilikia i ka hoʻāʻo ʻana i ka meaʻai
  • maka maka wai
  • nalo ʻai ʻole
  • Kaumaha emi
  • puʻuwai puʻuwai
  • nausea
  • ka luaʻi
  • pāhoehoe
  • kōpaʻa
  • ʻeha ka ʻōpū
  • ami, ʻami, a ʻeha hoʻi ka iwi
  • huikau
  • paʻakikī e hiamoe a hiamoe paha
  • nāwaliwali
  • luhi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • numbness, puhi ʻana, a i ʻole ka ʻūlū ʻana i nā lima a me nā wāwae paha
  • paʻakikī i ka hanu ʻana
  • hives
  • hūwī
  • ʻūlili
  • ʻula ʻulaʻula o ka maka, ka ʻāʻī a i ʻole ka umauma luna
  • pehu koke o ka maka, ka ʻāʻī a i ʻole ke alelo
  • kuʻi puʻuwai
  • ʻūpā
  • maule
  • ʻeha o ka umauma a i ʻole ke kūiki
  • loaʻa kaumaha kaumaha
  • fiva (100.5 ° F aʻoi aku paha)
  • haʻalulu
  • ʻūhā
  • ʻāʻī a ʻeha paha i ka wā e urination

Hoʻokumu paha ka injection Ixabepilone i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

  • ʻeha mākala
  • luhi

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • ʻIxempra®
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