Hōʻike Antibitochondrial Antibody Test (AMA)

Anter

• No ke aha i kauoha ʻia ai ka hōʻike AMA?
• Pehea ka lawelawe ʻana o ka hōʻike AMA?
• He aha nā pilikia o ka hōʻike AMA?
• Ka maopopo ʻana i nā hopena hōʻike AMA

He aha ka hōʻailona antimitochondrial antibody test?

Hoʻokumu ka mitochondria i ka ikehu no nā hunaola i kou kino e hoʻohana ai. Kūleʻa lākou i ka hana maʻamau o nā pūnaewele āpau.

ʻO nā Antimitochondrial antibodies (AMAs) kahi laʻana o ka pane autoimmune e kū ana i ka wā e huli kūʻē ke kino i kāna mau huna ponoʻī, nāʻaʻaʻa, a me nā lālā. Ke hiki kēia, hoʻouka ka ʻōnaehana pale i ke kino me he mea lā he maʻi ia.

Kuhi ka hōʻike AMA i ke kiʻekiʻe o kēia mau mea ʻino i loko o kou koko. Hoʻohana pinepine ʻia ka hōʻoia e ʻike i kahi kūlana autoimmune i ʻike ʻia ʻo cholangitis biliary mua (PBC), i ʻike ʻia ma mua he cirrhosis biliary mua.

No ke aha i kauoha ʻia ai ka hōʻike AMA?

Hoʻokumu ʻia ʻo PBC e kahi hoʻouka ʻōnaehana hōʻeuʻeu e pili ana i nā kaola liʻiliʻi o ke ake. Hoʻopilikia nā lāʻau ʻohe i nā scarring, a hiki i ka hopena o ke ake. Lawe pū kēia ʻano i ka hoʻonui i ka makaʻu o ka maʻi ʻaʻai ate.

Nā ʻōuli o PBC me:

• luhi
• ʻili ʻili
• melemele o ka ʻili, a i ʻole jaundice
• ʻeha ma ka ʻōpū ʻākau luna
• ka pehu ʻana, a i ʻole ka edema o nā lima a me nā wāwae
• he buildup o ka wai i loko o ka ʻōpū
• waha maloʻo a me nā maka
• Kaumaha emi

Hoʻohana ʻia kahi hōʻike AMA e kōkua i ka hōʻoia ʻana i ka ʻike lapaʻau a ke kauka o PBC. ʻAʻole lawa kahi hōʻike AMA maʻamau wale nō e hōʻoia i ka maʻi. Inā kū kēia, e kauoha paha kāu kauka i nā hoʻokolohua hou, e like me kēia:

Nā anti-nuklei (ANA): ʻO kekahi mau mea maʻi me PBC e hoʻāʻo hoʻi i ka maikaʻi no kēia mau mea ʻino.

Transaminases: ʻO nā enzymes alanine transaminase a me aspartate transaminase kikoʻī i ke ake. E ʻike ka hoʻāʻo ʻana i nā kālā i hoʻokiʻekiʻe ʻia, kahi hōʻailona o ka maʻi ate.

Bilirubin: ʻO kēia kahi mea a ke kino e hana ai ke haki nā hunaola ʻulaʻula. Hoʻopau ʻia ma o ka mimi a me ka pahu. Hiki i nā nui ke hōʻike i ka maʻi maʻi.

Albumin: ʻO kēia kahi protein i hana ʻia i ke akepaʻa. Hiki i nā pae haʻahaʻa ke hōʻike i ka hōʻino o ke ake a i ʻole nā ​​maʻi.

Pūmua C-reactive: Kauoha pinepine ʻia kēia hoʻāʻo e ʻike pono i ka lupus a i ʻole ka maʻi puʻuwai, akā hiki ke hōʻike ʻia i nā ʻano autoimmune ʻē aʻe.

Anati-ʻoluʻolu nāʻiʻo antibodies (ASMA): Lawe pinepine ʻia kēia hōʻike ma kaʻaoʻao o nā hōʻike ANA a he mea kūpono ia i ke kuhi ʻana i ka maʻi hematitis autoimmune.

Hiki ke hoʻohana ʻia ka hoʻokolohua AMA e nānā iā ʻoe no ka PBC inā hōʻike kahi hōʻike koko maʻamau he ʻoi aku kou kiʻekiʻe o nā alkaline phosphatase (ALP) ma mua o ka maʻamau. Hiki i kahi pae ALP kiʻekiʻe ke lilo i hōʻailona o ka maʻi bile a i ʻole ka maʻi gallbladder.

Pehea ka lawelawe ʻana o ka hōʻike AMA?

ʻO ka hōʻike AMA kahi hōʻike koko. E huki kahi kahu hānai a mea ʻenehana paha i kou koko mai kahi aa koko kokoke i kou kuʻe lima a lima paha. E hōʻiliʻili ʻia kēia koko i loko o kahi paipu a hoʻouna ʻia i kahi keʻena hoʻokolohua no ka loiloi.

E kāhea aku kāu kauka iā ʻoe e wehewehe i kāu mau hopena ke loaʻa lākou.

He aha nā pilikia o ka hōʻike AMA?

Hiki paha iā ʻoe ke ʻike i kahi hōʻoluʻolu ke huki ʻia ke kiʻi koko. Hiki ke ʻeha ma ka pūnaewele puncture i ka wā a ma hope paha o ka hoʻāʻo. Ma ka laulaha, he liʻiliʻi nā makaʻu o ke kahakaha koko.

ʻO nā pilikia e hiki ke hoʻopili ʻia:

• pilikia i ka loaʻa ʻana o kahi laʻana, e hopena ana i nā lāʻau ʻo ka nui
• nui ke kahe ʻana ma ke kahua o ka nila
• maule ma muli o ke kahe o ke koko
• hōʻiliʻili o ke koko ma lalo o ka ʻili, ʻike ʻia he hematoma
• maʻi ma ka puncture kahua

ʻAʻole pono kahi hoʻomākaukau no kēia hōʻike.

Ka maopopo ʻana i nā hopena hōʻike AMA

He maikaʻi ʻole nā ​​hopena hōʻike maʻamau no AMA. ʻO kahi AMA maikaʻi ke ʻike ʻia nā pae antibodies i ke kahe o ke koko. ʻOiai ʻo ka hoʻokolohua AMA maikaʻi e pili pinepine ʻia me PBC, hiki ke maikaʻi i ka hepatitis autoimmune, lupus, rheumatoid arthritis, a me ka maʻi graft-versus-host. ʻO kēia mau antibodies he mahele wale nō ia o kahi mokuʻāina autoimmune a ke kino e hana nei.

Inā loaʻa nā hopena maikaʻi, pono paha ʻoe i nā hoʻokolohua hou aku e hōʻoia i kāu ʻike. I ke kikoʻī, kauoha paha kāu kauka i kahi biopsy ate e lawe i kahi laʻana mai ke ake. E kauoha paha kāu kauka i kahi CT a MRI paha o kou ake.