Mea Kākau: Janice Evans
Lā O Ka Hana: 27 Iulai 2021
HōʻAno Hou I Ka Lā: 15 Nowemapa 2024
Anonim
Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson’s disease
Wikiō: Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson’s disease

Anter

Hoʻohana hoʻokahi ʻia ʻo Rasagiline a i ʻole hui pū ʻia me kahi lāʻau ʻē aʻe e mālama i nā ʻōuli o ka maʻi o Parkinson (kahi maʻi e hele lohi nei i ka ʻōnaehana hopohopo e hana ana i kahi helehelena paʻa me ka ʻole o ka helehelena, haʻalulu i ka hoʻomaha, ka lohi o ka neʻe ʻana, ka hele ʻana me nā ʻanuʻu shuffling, kūlou ke kūlana a me nā mākala nāwaliwali). Aia ʻo Rasagiline i loko o ka papa o nā lāʻau i kapa ʻia ʻo monoamine oxidase (MAO) ʻano B mea kāohi. Hana ia ma ka hoʻonui ʻana i ka nui o kekahi mau mea kūlohelohe i ka lolo.

Hele mai ʻo Rasagiline ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me ka ʻai ʻole. Lawe i ka rasagiline ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka rasagiline e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o rasagiline a hoʻonui paha i kāu lāʻau ma muli o ka pane o kou kino i kēia lāʻau.


Mai hōʻoki i ka lawe ʻana i ka rasagiline me ke kamaʻilio ʻole ʻana me kāu kauka. E hoʻoliʻiliʻi paha kāu kauka i kāu lāʻau. Inā kū koke ʻoe i ka lawe ʻana i ka rasagiline, ʻike paha ʻoe i ka haʻalele ʻana i nā hōʻailona e like me ke kuni; ʻoʻoleʻa o ka mākala; ʻaʻano ʻole, wobbliness, a hemahema paha o ka hoʻonohonoho ʻana; a i ʻole nā ​​hoʻololi ʻana i ka ʻike. E haʻi i kāu kauka inā ʻike ʻoe i kekahi o kēia mau ʻōuli ke hoʻemi ʻia kāu mahele lāʻau o rasagiline.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka rasagiline,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka rasagiline, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa rasagiline. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā ʻoe e lawe nei i nā huehue a me nā huahana anuanu i loko o dextromethorphan (DM; Delsym, Hold, Robitussin CoughGels, Vicks 44 Cough Relief, ma Robitussin DM, a me nā mea ʻē aʻe), cyclobenzaprine (Flexeril), meperidine (Demerol), methadone (Dolophine, Methadose ), propoxyphene (Darvon, ma Darvocet-N, a me nā mea ʻē aʻe), St. John's wort, a i ʻole tramadol (Ultram, i Ultracet). E haʻi pū aku i kāu kauka inā e lawe nei ʻoe i nā mea hoʻopuka MAO e like me phenelzine (Nardil), selegiline (Eldepryl), a i ʻole tranylcypromine (Parnate) a i ʻole ua oki ka lawe ʻana iā lākou i loko o nā pule ʻelua i hala. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka rasagiline inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: amphetamines (Adderall, Dexedrine, DextroStat); antidepressants; cimetidine (Tagamet); waiho ʻia nā decongestants i ka maka a i ʻole ka ihu; papaʻai a i ʻole nā ​​huahana kaohi-kaupaona i loko o ka ephedrine; ʻo nā lāʻau antibiotic fluoroquinolone me ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), norfloxacin (Noroxin), a me ofloxacin (Floxin); fluvoxamine (Luvox); nā lāʻau e mālama ai i ka hānō; nā lāʻau e mālama ai i ke koko kiʻekiʻe; nā lāʻau e mālama ai i ka maʻi noʻonoʻo; nā lāʻau e mālama ai i ka ʻeha; phenylpropanolamine (ʻaʻole loaʻa ma ka U.S.); pseudoephedrine (PediaCare, Sudafed, Suphedrine, nā mea ʻē aʻe); a me ka ticlopidine (Ticlid). E haʻi i kāu kauka inā lawe ʻoe i fluoxetine (Prozac, Sarafem) a i ʻole ua oki i ka lawe ʻana i loko o nā pule he 5 i hala. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i ke koko kiʻekiʻe, nā maʻi noʻonoʻo a psychosis paha; ka puʻuwai, a me nā maʻi ate.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka rasagiline, e kāhea i kāu kauka.
  • pono ʻoe e ʻike ʻo ka rasagiline ke kumu o ka hoʻoluhi, hoʻomālamalama, nausea, sweating, a maʻule hoʻi ke ala koke ʻoe mai kahi kūlana wahaheʻe. ʻOi aku kēia ma nā mahina ʻelua o ka lawe ʻana i ka rasagiline. I mea e hōʻalo ai i kēia pilikia, e hele mālie i waho o kahi moe, e hoʻomaha ana i kou mau wāwae i ka papahele no kekahi mau minuke ma mua o ke kū ʻana i luna.
  • pono ʻoe e ʻike ʻo ka rasagiline ke kumu o ke kahe o ke koko kiʻekiʻe ke hoʻoweliweli ʻia ke lawe ʻia me kekahi mau lāʻau a meaʻai paha. E mālama pono i nā kuhikuhi a kāu kauka e pili ana i nā lāʻau a me nā meaʻai e hōʻalo ai. Kāhea koke aku i kāu kauka inā loaʻa ʻoe i ka ʻeha o ke poʻo, ka ʻike maka ʻole, a i ʻole kekahi o nā ʻōuli ʻē aʻe i helu ʻia ma lalo e like me nā hopena ʻino.
  • pono ʻoe e ʻike ʻo ka poʻe i loaʻa i ka maʻi ʻo Parkinson he ʻoi aku ka nui o ka melanoma (kahi ʻano o ka maʻi ʻaʻai ʻili) ma mua o ka poʻe i loaʻa ʻole i ka maʻi ʻo Parkinson. ʻAʻole ʻike ʻia ka hopena o kēia maʻi hoʻonui ʻia e ka maʻi ʻo Parkinson, nā lāʻau i hoʻohana ʻia no ka maʻi ʻo Parkinson e like me rasagiline, a i ʻole nā ​​kumu ʻē aʻe. Pono ʻoe e kipa pinepine me kahi dermatologist e nānā i kou ʻili no melanoma.
  • pono ʻoe e ʻike i kekahi poʻe i lawe i ka rasagiline a i ʻole nā ​​lāʻau like e mālama i ka maʻi o Parkinson ua ʻike i nā koi ikaika e pāʻani, hoʻonui i nā makemake moekolohe, a me nā koi ʻē aʻe i hiki ʻole iā lākou ke kaohi. E haʻi aku i kāu kauka inā ʻike ʻoe i nā makemake hou a hoʻonui paha i nā pāʻani pāʻani, hoʻonui i nā makemake moekolohe, a i ʻole nā ​​ʻōlelo ikaika ʻē aʻe i ka lawe ʻana i ka rasagiline.

Pono ʻoe e hōʻalo i ka ʻai ʻana i nā meaʻai i piha i ka nui o ka tyramine, e like me nā uahi ʻelemakule (e laʻa me, Stilton a i ʻole ka waiū polū) i kou wā e mālama ʻia ai me ka rasagiline. E kamaʻilio me kāu kauka a mea ʻaʻai paha e pili ana i nā meaʻai āu e hōʻalo ai i ka wā o kāu mālama ʻana a i ʻole inā ʻaʻole ʻoe e manaʻo maikaʻi ma hope o ka ʻai ʻana a inu paha i kekahi mau meaʻai i ka lawe ʻana i ka rasagiline.


Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.Hōʻalo i ka lāʻau i hala a lawe i kāu kau ma hope i ka manawa maʻamau i ka lā aʻe.

Hoʻokumu paha ʻo Rasagiline i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻeha poʻo poʻo
  • ʻeha puʻupuʻu a ʻāʻī paha
  • puʻuwai puʻuwai
  • nausea
  • ka luaʻi
  • ʻeha ka ʻōpū
  • kōpaʻa
  • pāhoehoe
  • nalo ʻai ʻole
  • Kaumaha emi
  • nā ʻōuli like flu
  • fiva
  • ka houʻu ʻana
  • ʻulaʻula, ʻōhū, a me / a i ʻole nā ​​maka maka makaʻu
  • waha maloo
  • gums pehu
  • ʻaʻano ʻole, wobbliness, a i ʻole nele i ka hoʻohui ʻana
  • neʻe ʻole, hoʻoneʻe kino
  • nele i ka ikaika
  • hiamoe
  • moeʻuhane ʻino
  • kaumaha
  • ʻeha, puhi ʻana, numbness, a ʻūlū paha i nā lima a me nā wāwae
  • hūwī
  • paopao a poni paha, discoloration ma ka ʻili

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • ʻeha poʻo poʻo
  • ʻike hihi
  • ka hopu ʻana
  • ʻeha ka umauma
  • pōkole o ka hanu a paʻakikī hoʻi i ka hanu ʻana
  • huikau
  • ʻike ʻole
  • ʻolelo lohi a paʻakikī paha
  • paupauaho a maʻule paha
  • nāwaliwali a i ʻole ka helu ʻana o ka lima a me ka wāwae
  • hallucinating (ke ʻike nei i nā mea a i ʻole ka lohe ʻana i nā leo i ʻole)
  • hoʻomaha ʻole loa
  • paʻakikī i ka noʻonoʻo ʻana a i ʻole ka hoʻomaopopo ʻana i ka ʻoiaʻiʻo

Hoʻokumu paha ʻo Rasagiline i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki ke loaʻa nā ʻōuli o ka overdose rasagiline ma mua o 1 a 2 mau lā ma hope o ka overdose. Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • hiamoe
  • ʻūpā
  • maule
  • ukiuki
  • hyperactivity
  • hoʻonāukiuki a hoʻomaha ʻole paha
  • ʻeha poʻo poʻo
  • hoʻāno
  • huikau
  • nalo o ke kūlike
  • paʻakikī e hāmama ka waha
  • spasm o ke kino ʻoʻoleʻa e komo pū paha me kahi kua i hoʻopaʻa ʻia
  • ʻili mākala
  • ka hopu ʻana
  • nalowale o ka ʻike
  • wikiwiki a pā ʻole paha ka puʻuwai
  • ʻeha ma kahi ma waena o ka ʻōpū a me ka umauma
  • pilikia i ka hanu ʻana a i ʻole ka hanu ʻana o ka hanu
  • pāhoehoe
  • fiva
  • ka houʻu ʻana
  • ʻili maikaʻi, ʻili ʻōpala
  • haʻalulu
  • hoʻonui i ka nui o nā haumāna (pōʻaiʻele i waenakonu o ka maka)

Mālama i nā manawa āpau me kāu kauka.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 07/15/2016

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