CMV - gastroenteritis / colitis

ʻO CMV gastroenteritis / colitis ka mumū o ka ʻōpū a i ʻole ka ʻōpū ma muli o ka maʻi me cytomegalovirus.

Hiki i kēia virus ke hana pū:

• Maʻi ʻaʻai
• ʻO ka maʻi ma ka hope o ka maka
• Nā maʻi ʻino o kahi pēpē ʻoiai ia i loko o ka ʻōpū

ʻO Cytomegalovirus (CMV) kahi maʻi maʻi herpes-type. Pili ia i ka maʻi hoʻomaʻemaʻe ke kumu o ka moa.

ʻO ka maʻi me CMV ka mea maʻamau. Hoʻolahalaha ʻia e ka lihi, ka mimi, nā pulu hanu, ka pilina kolohe, a me nā hoʻokahe koko. Hōʻike ka hapa nui o ka poʻe i kekahi manawa, akā ʻo ka hapanui o ka manawa, hoʻopuka ka virus i nā ʻano akahai a ʻaʻohe paha i nā kānaka olakino.

Hiki i nā maʻi CMV koʻikoʻi ke kū i ka poʻe me nā ʻōnaehana pale nawaliwali ma muli o:

• AIDS
• Mālama Chemotherapy no ka maʻi ʻaʻai
• I ka wā a ma hope paha o ka iwi iwi a i ʻole ke hoʻoneʻe ʻana o ke koʻokoʻo
• Ulcerative colitis a i ʻole Crohn maʻi

Kākaʻikahi ka maʻi CMV koʻikoʻi e pili ana i ka GI tract i loko o ka poʻe me kahi ʻōnaehana pale ola olakino.

Hiki i ka maʻi Gastrointestinal CMV ke hoʻopili i kahi mahele a i ʻole ke kino holoʻokoʻa. Hiki i nā ulcer i loko o ka esophagus, ʻōpū, ʻōpū liʻiliʻi, a i ʻole kolone. Pili kēia mau ulcer me nā ʻōuli e like me:

• Abdominal eha
• Pilikia i ka ale ʻana a i ʻole ka ʻeha me ka ale ʻana
• Nusea
• ʻO ka luaʻi

Ke pili nei nā ʻōpū, hiki i nā maʻi ulcer ke kumu:

• Abdominal eha
• Nā noho koko
• Pohā
• Fiva
• Kaumaha emi

Hiki i nā maʻi ʻino keu aʻe ke hopena i ke kahe ʻana o ka gastrointestinal a i ʻole ka puka ma o ka paia o ka ʻōpū (perforation).

ʻO nā hoʻāʻo e hana ʻia ana paha:

• Enema Barium
• ʻO Colonoscopy me ka biopsy
• ʻO endoscopy luna (EGD) me ka biopsy
• ʻO ka moʻomeheu Stool e kāpae i nā kumu ʻē aʻe o ka maʻi
• ʻO GI luna a me nā pūʻali ʻōpū liʻiliʻi

E hana ʻia nā hoʻokolohua Laboratory ma kahi laʻana o nā kiko i lawe ʻia mai kou ʻōpū a i ʻole kou ʻōpū. ʻO nā hoʻokolohua, e like me kahi moʻomeheu ʻōpū a ʻōpū paha a i ʻole biopsy, e hoʻoholo inā aia ka maʻi ma kaʻiʻo.

Hana ʻia kahi hōʻike serology CMV e nānā i nā mea ʻino i ka maʻi CMV i kou koko.

ʻO kekahi hōʻike koko e nānā i ke alo a me ka helu o nā huna ʻino i loko o ke koko.

Hoʻomaʻamaʻa ʻia ka mālama ʻana i ka maʻi a hōʻoluʻolu i nā ʻōuli.

Kau ʻia nā lāʻau e hakakā ai i ka maʻi (nā lāʻau antiviral). Hāʻawi ʻia nā lāʻau i loko o ke aa (IV), a i kekahi manawa me ka waha, no kekahi mau pule. ʻO nā lāʻau i hoʻohana mau ʻia ʻo ganciclovir a me valganciclovir, a me foscarnet.

I kekahi mau hihia, pono paha ka hoʻōla wā lōʻihi. Hiki ke hoʻohana ʻia kahi lāʻau i kapa ʻia ʻo CMV hyperimmune globulin ke holo ʻole nā ​​lāʻau ʻē aʻe.

Pili pū nā lāʻau ʻē aʻe:

• Nā lāʻau e pale a hoʻēmi paha i ka palahī
• Painkillers (analgesics)

Hiki ke hoʻohana ʻia nā mea hoʻopihapiha a me nā meaʻai i hāʻawi ʻia ma o ke aa (IV) e mālama ai i ka nalo ʻana o nā mākala no ka maʻi.

I ka poʻe me ka ʻōnaehana pale olakino olakino, hele aku nā ʻōuli me ka ʻole o ka lapaʻau ʻana i ka hapanui o nā hihia.

ʻOi aku ka nui o nā ʻōuli ma nā mea me ka ʻōnaehana pale nawaliwali. Pili ka hopena i ka nui o ka hemahema o ka ʻōnaehana pale a me ka maʻi CMV.

ʻOi aku paha ka hopena o ka poʻe me ka maʻi AIDS ma mua o ka poʻe me ka ʻōnaehana pale nawaliwali ma muli o kekahi kumu.

Hoʻopili pinepine ka maʻi CMV i ke kino holoʻokoʻa, ʻoiai inā aia nā ʻōpū gastrointestinal wale nō. Maikaʻi ka hilinaʻi ʻana o ke kanaka i ka maikaʻi o ka hana ʻana o nā lāʻau antiviral.

ʻO nā lāʻau i hoʻohana ʻia e kaua i ka maʻi he hopena paha. Pili ke ʻano o ka hopena i ka lāʻau i hoʻohana ʻia. ʻO kahi laʻana, hiki i ka lāʻau ganciclovir ke hoʻohaʻahaʻa i kāu helu keʻokeʻo koko keʻokeʻo. ʻO kekahi lāʻau lapaʻau, foscarnet, hiki ke alakaʻi i nā pilikia o ka hakuʻala.

Kāhea i kāu mea mālama ola inā loaʻa nā ʻōuli o CMV gastroenteritis / colitis.

Loaʻa ka makaʻu nui i ka maʻi CMV i ka poʻe i loaʻa i kahi transplant organ mai kahi mea hāʻawi manawaleʻa CMV. Lawe i nā lāʻau antiviral ganciclovir (Cytovene) a me valganciclovir (Valcyte) e ka waha ma mua o ka hiki i ke transplant ke hoʻohaʻahaʻa i kou manawa e loaʻa ai kahi maʻi hou a i ʻole ke hoʻoulu hou ʻana i kahi maʻi kahiko.

ʻO ka poʻe me ka maʻi SIDA e mālama maikaʻi ʻia me ka antiretroviral therapist ikaika loa ka liʻiliʻi e loaʻa i kahi maʻi CMV.

Colitis - cytomegalovirus; Gastroenteritis - cytomegalovirus; ʻO ka maʻi CMV Gastrointestinal

• Anatomia Gastrointestinal
• ʻŌpū a me ka ʻōpū o ka ʻōpū
• CMV (cytomegalovirus)

ʻO Britt WJ. Cytomegalovirus. I: Bennett JE, Dolin R, Blaser MJ, hua pā. ʻO Mandell, Douglas, a me Bennett's Principle a me ka hoʻomaʻamaʻa ʻana i nā maʻi kūpilikiʻi. 9th ed. Piladelapia, PA: Elsevier; 2020: chap 137.

ʻO Dupont HL, ʻO Okhuysen PC. E hoʻokokoke i ka mea maʻi me ka maʻi ʻino i komo ʻia. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 267.

Larson AM, Issaka RB, Hockenbery DM. Gastrointestinal a me nā pilikia hepatic o ka mea paʻa a me ka hematopoietic cell transplantation. I: Feldman M, Friedman LS, Brandt LJ, eds. ʻO Sleisenger a me Fordtran's Gastrointestinal a me ka maʻi ate. 11th hua. Piladelapia, PA: Elsevier; 2021: chap 36.

ʻO Wilcox CM. Nā hopena Gastrointestinal o ka maʻi me ka maʻi pale maʻi kanaka. I: Feldman M, Friedman LS, Brandt LJ, eds. ʻO Sleisenger a me Fordtran's Gastrointestinal a me ka maʻi ate. 11th hua. Piladelapia, PA: Elsevier; 2021: chap 35.