Histiocytosis: he aha ia, nā ʻōuli a me nā lāʻau

Anter

• Nā hōʻailona nui
• Pehea e hana ʻia ai ke kuhi
• Pehea e mālama ai

Kūlike ka Histiocytosis i kahi hui o nā maʻi i hiki ke ʻike ʻia e ka hana nui a me ke kū ʻana o nā histiocytes e kahe ana i loko o ke koko, ʻoiai, he kakaikahi, ʻoi aku ka pinepine i nā kāne a hana ʻia kāna ʻike i nā makahiki mua o ke ola, ʻoiai nā ʻōuli hōʻailona. hiki ke ʻike ʻia ka maʻi i kēlā me kēia makahiki.

ʻO nā histiocytes nā hunaola i loaʻa mai i nā monocytes, nā hunaola ia no ka ʻōnaehana pale, a no laila ke kuleana no ka pale ʻana i ka meaola. Ma hope o ke kaʻina hana o ka hoʻokaʻawale ʻana a me ka ulu ʻana, ʻike ʻia nā monocytes macrophages, i hāʻawi ʻia i kahi inoa kikoʻī e like me kahi i kū ai i loko o ke kino, i kapa ʻia ʻo nā pūnaewele Langerhans ke loaʻa i loko o ka epidermis.

ʻOiai ʻoi aku ka pili o ka histiocytosis i nā loli hanu, hiki ke hōʻiliʻili ʻia nā histiocytes i nā lālā ʻē aʻe, e like me ka ʻili, nā iwi, ka ate a me nā ʻōnaehana, e hopena ana i nā ʻōuli like ʻole e like me ka wahi o ka hoʻolaha nui loa o nā histiocytes.

Nā hōʻailona nui

Hiki i ka histiocytosis ke asymptomat a i ʻole ka holomua i ka hoʻomaka koke ʻana o nā ʻōuli. Hiki ke hoʻololi i nā hōʻailona a me nā hōʻailona e hōʻike ana i ka histiocytosis e like me ka wahi kahi i ʻoi aku ka nui o nā histiocytes. No laila, nā hōʻailona nui:

• Cough;
• Fiva;
• Ka hōʻemi kaumaha me ke kumu ʻole;
• Hanu paʻakikī;
• Luhi nui loa;
• Anemia;
• ʻOi aku ka makaʻu o nā maʻi;
• Nā pilikia Coagulation;
• ʻEha nā ʻili;
• Abdominal eha;
• Huikau;
• Hoopaneeia ka oo ana;
• Puʻupuʻu.

Hiki i ka nui o nā histiocytes ke hopena i ka hana nui ʻana o nā cytokine, e hoʻonāukiuki i ke kaʻina hana hoʻomālamalama a hoʻonāukiuki i ka hoʻokumu ʻia ʻana o nā tumors, me ka hoʻohui ʻana i ka hōʻino ʻana i nā ʻāpana kahi i hōʻoia ʻia ai ka hōʻiliʻili ʻana o kēia mau pūnaewele. ʻOi aku ka maʻamau o ka histiocytosis e hoʻopili i ka iwi, ka ʻili, ka ate a me nā akemāmā, keu hoʻi inā he mōʻaukala ka puhipaka. ʻO ka liʻiliʻi pinepine, hiki i ka histiocytosis ke hoʻopili i ka ʻōnaehana waena, nā lymph node, nā ʻōpū o ka gastrointestinal a me ka thyroid.

Ma muli o ka hoʻomohala maikaʻi ʻole ʻia o nā ʻōnaehana pale ʻino o nā keiki, hiki paha ke hoʻopili ʻia me ka maʻalahi o kekahi mau ʻokanala, a he mea nui ka hoʻomaka mua ʻana o ka lāʻau.

Pehea e hana ʻia ai ke kuhi

ʻO ke kuhi o ka histiocytosis i hana nui ʻia e ka biopsy o ka pūnaewele i hoʻopilikia ʻia, kahi e hiki ai ke ʻike ʻia ma o ka loiloi ʻana o ka hale hana ma lalo o kahi microscope, ke kū ʻana o kahi infiltrate me ka hoʻonui ʻia o nā histiocytes i loko o ka mea i olakino ma mua.

Hoʻohui ʻia, nā hoʻokolohua ʻē aʻe e hōʻoia i ka hōʻoia, e like me ka tomography compute, ka noiʻi no nā hoʻololi e pili ana i kēia maʻi, e like me BRAF, no ka laʻana, me ka hoʻohui ʻana i nā hoʻokolohua immunohistochemical a me ka helu o ke koko, kahi e loli ai ka nui o nā neutrophil. , nā lymphocytes a me nā eosinophils.

Pehea e mālama ai

ʻO ka mālama ʻana i ka histiocytosis kaukaʻi ʻia i ka nui o ka maʻi a me ka wahi i hoʻopilikia ʻia, a me ka chemotherapy, radiotherapy, ka hoʻohana ʻana i nā lāʻau immunosuppressive a i ʻole ke ʻoki kino, e pili ana i ka hihia o ka iwi i pili. Ke hoʻokumu ʻia ka histiocytosis e ka puhipaka, no ka laʻana, paipai ʻia ka hoʻomaha puhipaka, e hoʻomaikaʻi maikaʻi i ke ʻano o ka mea maʻi.

ʻO ka hapa nui o ka manawa, hiki i ka maʻi ke hoʻōla iā ia iho a nalowale paha ma muli o ka mālama ʻana, akā hiki nō ke hoʻi hou. No laila, he mea nui e nānā mau ʻia ke kanaka i hiki ai i ke kauka ke nānā inā aia kahi pilikia o ka hoʻomohala ʻana i ka maʻi a, no laila, hoʻokumu i ka lāʻau i nā wā mua.