Nā H2 Receptor Blockers

Anter

• He aha nā H2 Receptor Blockers?
• Pehea e hana ai i nā H2 Receptor Blockers?
• He aha nā hopena ʻaoʻao o nā H2 Receptor Blockers?
• H2 Receptor Blockers vs. Proton Pump Inhibitors (PPI)
• Nā Hana Hou
• Q:
• A:

I ʻApelila 2020, ua noi ʻia e hoʻopau i nā ʻano o ke kuhikuhi a me ka over-the-counter (OTC) ranitidine (Zantac) mai ka mākeke U.S. Ua hana ʻia kēia ʻōlelo aʻoaʻo no ka mea ʻaʻole i ʻāpono nā pae o NDMA, kahi carcinogen paha (kemikō e hoʻomaka ana i ka maʻi ʻaʻai), i loaʻa i kekahi mau huahana ranitidine. Inā kuhikuhi ʻoe iā ranitidine, e kamaʻilio me kāu kauka e pili ana i nā koho koho palekana ma mua o ka hoʻokū ʻana i ka lāʻau. Inā lawe ʻoe i ka OTC ranitidine, e hoʻōki i ka lawe ʻana i ka lāʻau a kamaʻilio pū me kāu kauka no nā koho ʻē aʻe. Ma kahi o ka lawe ʻana i nā huahana ranitidine i hoʻohana ʻole ʻia i kahi pūnaewele hoʻihoʻi i ka lāʻau, hoʻolei iā lākou e like me nā ʻōlelo a ka huahana a i ʻole ma ka mālama ʻana iā FDA.

He aha nā H2 Receptor Blockers?

ʻO ka H2 receptor blockers kahi papa o nā lāʻau i hiki ke hoʻohana ʻia e mālama ai i nā ʻano e kumu ai ka waikawa ʻōpū nui. Loaʻa kēia mau lāʻau i luna o ka pāʻai a me ke kauka. ʻO nā poloka receptor H2 maʻamau ka:

• nizatidine (Axid)
• famotidine (Pepcid, Pepcid AC)
• cimetidine (Tagamet, Tagamet HB)

Hoʻohana pinepine ʻia ka H2 receptor blockers e mālama i ka gastritis, a i ʻole ka ʻōpū i hoʻomāhuahua, a me ka mālama ʻana i nā maʻi maʻi peptic. ʻO nā maʻi maʻi peptic nā ʻeha ʻeha e hana ʻia i ka pale o ka ʻōpū, esophagus lalo, a i ʻole duodenum, ʻo ia ka ʻāpana mua o ka ʻōpū liʻiliʻi. Hoʻolālā pinepine lākou ma muli o ka mumū a me ka nui o ka waikawa ʻōpū. Hiki paha i nā kauka ke koi aku i nā mea hoʻopaʻa pale H2 e mālama i nā maʻi peptic mai ka hoʻi ʻana.

Hoʻohana pinepine ʻia nā poloka H2 receptor e hōʻoluʻolu i nā ʻōuli o ka maʻi reflux gastroesophageal (GERD). ʻO GERD kahi ʻano mau o ka reflux acid, i kumu e kahe hou ai i loko o ka ʻōpū acidic i loko o ka esophagus. Hiki ke hoʻonāukiuki pinepine i ka waikawa ʻōpū ke hoʻonāukiuki i ka esophagus a alakaʻi i nā ʻōuli hōʻoluʻolu ʻole, e like me ka puʻuwai puʻuwai, nausea, a i ʻole ka pilikia e ale.

Hiki ke hoʻohana ʻia nā mea pale H2 e mālama ai i nā kūlana maʻa mau e like me Zollinger-Ellison Syndrome, kahi ʻano e hoʻonui ai i ka hana o ka ʻōpū o ka ʻōpū.

Paipai paha nā kauka iā H2 nā poloka receptor no ka hoʻohana inoa ʻole. ʻO kēia ka hoʻohana ʻana i ka lāʻau e mālama ai i kahi kūlana i ʻae ʻole ʻia e lāʻau. ʻO kahi laʻana, hiki ke hoʻohana ʻia nā blockers receptor H2 e mālama i nā pilikia pancreatic a i ʻole hoʻohana ʻia i nā hihia o ka hopena maʻi ʻaʻa, ʻoiai ʻaʻole hoʻohana maʻamau ʻia no kēia mau kumu.

Pehea e hana ai i nā H2 Receptor Blockers?

Ke lawe ʻoe i kahi H2 receptor blocker, huakaʻi nā mea hana i nā mea loaʻa kikoʻī ma ka papa o nā ʻōpū o ka ʻōpū e hoʻokuʻu i nā waikawa. Hoʻopili ka lāʻau i kekahi mau hopena kemika i kēia mau hunaola i hiki ʻole iā lākou ke hana i ka nui o ka waikawa. Wahi a ka National Institutes of Health, H2 receptor blockers hoʻohaʻahaʻa i nā huna acid acid ma luna o 24 mau hola e 70 pākēneka. Ma ka hoʻemi ʻana i ka nui o ka waikawa i loko o ka ʻōpū, ʻae ʻia nā kino i hōʻino ʻia i ka manawa e hoʻōla ai.

He aha nā hopena ʻaoʻao o nā H2 Receptor Blockers?

ʻO ka hapa nui o nā hopena ʻē aʻe e pili ana me nā H2 receptor blockers he akahai a maʻa mau i ka wā e lawe ai ke kanaka i ka lāʻau i ka manawa. ʻO 1.5 wale nō ka pākēneka o ka poʻe e hōʻoki i ka lawe ʻana i nā H2 receptor blockers ma muli o nā hopena ʻaoʻao.

ʻO kekahi o nā hopena i hiki ke kū ʻia me nā H2 receptor blockers pū me:

• kōpaʻa
• pāhoehoe
• paʻakikī i ka hiamoe
• waha maloo
• ʻili maloʻo
• ʻeha poʻo
• kani i nā pepeiao
• he ihu ihope
• pilikia urino

Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi mau hōʻailona ʻē aʻe āu e manaʻo ai ma muli o ka lawe ʻana i kahi H2 receptor blocker.

I nā hihia maʻamau, hiki i nā H2 receptor blockers ke kumu i nā hopena ʻino ʻoi aʻe, e like me:

• ʻili, ʻā, a ʻili paha ka ʻili
• nā hoʻololi i ka hihiʻo
• huikau
• hoohaunaele
• paʻakikī i ka hanu ʻana
• ʻūhā
• paʻa paʻa o ka umauma
• kuʻi naʻau kaulike ʻole
• nā ʻōlelo hoʻohiwahiwa
• manaʻo suicidal

Kāhea i kāu kauka a hele koke i ka haukapila inā ʻike ʻoe i kekahi o kēia mau ʻōuli.

Me nā hopena hopena e hiki ai, ʻo ka H2 receptor blockers ka mea maʻamau he lāʻau maikaʻi loa no nā kūlana e kumu i ka waikawa ʻōpū nui. Hiki iā ʻoe a me kāu kauka ke kūkākūkā i nā pilikia e hiki mai ana a hoʻoholo inā ʻo ka H2 receptor blockers ke koho ʻoi loa no kāu kūlana. ʻAʻole pono ʻoe e hōʻoki i ka lawe ʻana i kāu lāʻau me ke kamaʻilio ʻole ʻana me kāu kauka e pili ana.

H2 Receptor Blockers vs. Proton Pump Inhibitors (PPI)

ʻO nā mea pale lāʻau Proton pump (PPI) kekahi ʻano lāʻau i hoʻohana ʻia e hōʻemi i ka acid acid a mālama i ka reflux acid a i ʻole GERD. ʻO nā laʻana o nā PPI me ka esomeprazole (Nexium) a me ka pantoprazole (Protonix).

Hana nā lāʻau ʻelua i ka pale ʻana a me ka hōʻemi ʻana i ka hana ʻana o ka waikawa ʻōpū, akā manaʻo ʻia ʻo PPI ʻoi aku ka ikaika a me ka wikiwiki i ka hōʻemi ʻana i nā waikawa ʻōpū. Eia nō naʻe, hoʻoliʻiliʻi pono nā mea hoʻopaʻa H2 i ka waikawa i hoʻokuʻu ʻia i ke ahiahi, kahi mea hāʻawi maʻamau i nā maʻi maʻi peptic. ʻO kēia ke kumu i kuhikuhi kikoʻī ʻia ai nā H2 receptor blockers i ka poʻe i loaʻa i ka maʻi maʻi a i ʻole ka makaʻu no ka loaʻa ʻana iā lākou. Hoʻonohonoho pinepine ʻia nā PPI no nā poʻe i loaʻa ka GERD a i ʻole ka reflux acid.

ʻAʻole makemake nā kauka e lawe i kahi PPI a me ka H2 receptor blocker i ka manawa like. Hiki i nā H2 receptor blockers ke hoʻopili i ka pono o nā PPI. Inā hoʻomaikaʻi ʻole kāu mau hōʻailona GERD me ka hoʻohana ʻana o kahi PPI, hiki i kāu kauka ke koi aku i kahi H2 receptor blocker ma kahi.

Nā Hana Hou

Inā loaʻa iā ʻoe nā maʻi maʻi peptic a i ʻole GERD, e paipai paha kāu kauka iā ʻoe e hōʻalo i ka lawe ʻana i nā lāʻau kikoʻī a hana ʻoe i kekahi ʻano loli e hōʻoluʻolu i kāu mau ʻōuli.

Inā loaʻa iā ʻoe nā maʻi maʻi peptic, hiki i kāu kauka ke koi aku iā ʻoe e kaupalena i kāu hoʻohana ʻana i nā lāʻau anti-inflammatory nonsteroidal (NSAIDs), e like me ka aspirin a me ka ibuprofen. ʻO ka hoʻohana pinepine a lōʻihi ʻana o kēia ʻano ʻano lāʻau hiki ke hoʻonui i kou makaʻu no ka maʻi ulcer peptic. E ʻōlelo paha kāu kauka e lawe ʻoe i acetaminophen ma kahi. Eia naʻe, ʻaʻole pono ʻoe e hōʻoki i ka lawe ʻana i nā lāʻau me ka ʻole e kamaʻilio mua i kāu kauka.

Hiki i ka hoʻoponopono ʻana i ke ʻano o ke ola ke kōkua i ka hōʻemi ʻana i nā maʻi peptic ulcer. Pākuʻi ʻia kēia mau mea:

• ka palena ʻana i ka inu lama
• ka hōʻalo ʻana i nā meaʻai nīoi
• hoʻemi ana i ke koʻikoʻi
• hoʻōki puhipaka

Inā loaʻa iā GERD a i ʻole reflux waikawa, nā hoʻoponopono ola e hiki ai ke hōʻoluʻolu i nā hōʻailona me:

• e ʻai ana i nā pāʻina liʻiliʻi i kēlā me kēia lā ma kahi o ʻekolu nui
• ka hōʻalo ʻana i ka ʻalekohola, ka paka, a me nā meaʻai a me nā mea inu i ʻike ʻia e hoʻomaka ai nā ʻōuli
• ke hoʻokiʻekiʻe nei i ke poʻo o kahi moe ma kahi o 6 ʻīniha
• ʻai liʻiliʻi momona
• e hōʻalo ana i ka moe ʻana ma lalo o ʻelua mau hola ma hope o ka ʻai ʻana
• e hōʻalo nei i nā meaʻai māmā ma mua o ka hiamoe

E kamaʻilio me kāu kauka inā ʻaʻole hoʻomaikaʻi kāu mau ʻōuli me ka lāʻau a i ʻole nā ​​ʻano nohona. Pono ʻoe i kahi lāʻau hoʻomāinoino a i ʻole ʻoki kino e hoʻopau ai i kahi ulcer a hoʻēmi paha i ka reflux acid.

Pono ʻoe e ʻimi koke i ka lāʻau inā loaʻa kekahi o kēia mau ʻōuli:

• hoʻomohala ʻoe i ka ʻeha o ka ʻōpū ʻoi aku ka maikaʻi ma mua o ka maʻa i ka ʻike ʻana
• ulu ʻoe i ke kuni kiʻekiʻe
• ʻike ʻoe i ka luaʻi ʻaʻole maʻalahi maʻalahi
• hoʻomohala ʻoe i ka puʻupuʻu a me ka ʻālohilohi

ʻO kēia nā hōʻailona o nā pilikia mai ka maʻi peptic ulcer pono pono e kamaʻilio koke.

Q:

Aia kekahi e pono ʻole e lawe i nā mea hoʻopaʻa H2 receptor?

A:

ʻO nā mea maʻi wale nō i loaʻa nā hopena koʻikoʻi a weliweli paha i nā mea pale H2 e hōʻalo i ka lawe ʻana iā lākou. ʻO kēia papa o ka lāʻau lapaʻau he mahele B i ka hāpai keiki ʻo ia hoʻi he palekana ke lawe i ka wā hāpai.