Hōʻike koko Alpha-1 antitrypsin

ʻO Alpha-1 antitrypsin (AAT) kahi hoʻokolohua hoʻokolohua e ana i ka nui o AAT i kou koko. Hana ʻia ka hōʻoia e nānā ai i nā ʻano maʻamau o ka AAT.

Pono kahi laʻana koko.

ʻAʻohe hoʻomākaukau kūikawā.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.

He mea kōkua kēia hōʻike i ka hoʻomaopopo ʻana i kahi ʻano laha ʻole o ka emphysema i nā mākua a me kahi ʻano laha ʻole o ka maʻi ate (cirrhosis) i nā keiki a me nā mākua i hoʻokumu ʻia e ka hemahema AAT. Hoʻolilo ʻia ka hemahema AAT i loko o nā ʻohana. Hoʻokumu ke ʻano i ke akepaʻa e hana liʻiliʻi loa i ka AAT, kahi protein e pale ai i nā akemāmā a me ke ake mai ka pohō.

He ʻelua kope o kēlā me kēia kanaka i ka ʻāpana e hana iā AAT. ʻO nā kānaka me nā kope ʻelua ʻole o ka gen i loaʻa i nā maʻi ʻoi loa a me nā kiʻekiʻe o ke koko.

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.

Hiki ke hoʻopili ʻia kahi pae haʻahaʻa ma mua o ka maʻamau o AAT me:

• Ka poino o nā ala nui i nā akemāmā (bronchiectasis)
• Scarring o ke ake (cirrhosis)
• ʻO ka maʻi pulmonary obstructive maʻi (COPD)
• ʻ Liverpū puʻukū
• Melemele o ka ʻili a me nā maka ma muli o ke kahe ʻana o ka bile (obunductive jaundice)
• ʻO ke kahe kiʻekiʻe i ke aa nui e alakaʻi i ke ake (portal hypertension)

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi, a mai kekahi ʻaoʻao o ke kino i kekahi ʻē aʻe. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula manawa o ka ili i haki)

Hōʻike A1AT

Chernecky CC, Berger BJ. ʻAlepa₁-antitrypsin - serum. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 121-122.

ʻO Winnie GB, ʻo Boas SR. a₁ - Antitrypsin nele a me ka emphysema. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 421.