Mea Kākau: Clyde Lopez
Lā O Ka Hana: 26 Iulai 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
Methimazole and Propylthiouracil (PTU) - Mechanism of Action, Indications, and Side Effects
Wikiō: Methimazole and Propylthiouracil (PTU) - Mechanism of Action, Indications, and Side Effects

Anter

Hoʻokumu paha ʻo Propylthiouracil i ka hōʻino o ke ake i nā mākua a me nā keiki. ʻO kekahi poʻe i lawe i propylthiouracil pono i nā transplants ate a make kekahi poʻe ma muli o ka hōʻino o ke ake. Ma muli o kēia pilikia, pono e hāʻawi wale ʻia ka propylthiouracil i ka poʻe i hiki ʻole ke loaʻa nā lāʻau ʻē aʻe e like me ke ʻoki ʻana, iodine radioactive, a i ʻole nā ​​lāʻau ʻokoʻa i kapa ʻia ʻo methimazole (Tapazole). Hāʻawi ʻia ka Propylthiouracil i nā wahine i nā mahina mua (ma kahi o 12 mau pule) o ka hāpai ʻana no ka mea hiki i ka methimazole ke hana i nā kīnā hānau inā hoʻohana ʻia i kēia ʻāpana o kahi hāpai.

Inā ʻoe e lawe propylthiouracil, e kāhea koke i kāu kauka inā hoʻomohala ʻoe i kekahi o nā ʻōuli e hiki mai ana: ka fiva, ka pau ʻole o ka makemake, ka paupō, ka luaʻi, ka luhi, ka ʻume, ka mimi ʻeleʻele, nā pale lau a i ʻole nā ​​kukui ʻalani, melemele o ka ʻili a me nā maka, a i ʻole. ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me propylthiouracil a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm).


Hoʻohana ʻia ʻo Propylthiouracil e mālama i ka hyperthyroidism (kahi ʻano e hana ʻia ke hana ka thyroid gland i ka nui o ka hormone thyroid, e wikiwiki ana i ka metabolism o ke kino, a hana i kekahi mau ʻōuli) i nā mākua a me nā keiki 6 makahiki a ʻoi paha. Aia ʻo Propylthiouracil i kahi papa o nā lāʻau i kapa ʻia he agithyroid agents. Hana ia ma ka hoʻōki ʻana i ka gland thyroid mai ka hana ʻana i ka hōmona thyroid.

Hele mai ʻo Propylthiouracil ma ke ʻano he papa e lawe ma ka waha. Lawe pinepine ʻia ia ʻekolu manawa i ka lā, hoʻokahi manawa i kēlā me kēia 8 hola. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i propylthiouracil e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o propylthiouracil ke kaohi ʻia kou ʻano.

E hoʻomau i ka lawe propylthiouracil ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka propylthiouracil me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.


Ma mua o ka lawe propylthiouracil,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i propylthiouracil, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa propylthiouracil. E noi i kāu kauka a kauka paha a e nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: anticoagulants ('blood thinners') e like me warfarin (Coumadin), beta blockers e like me atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), a propranolol (Inderal); digoxin (Digitek, Lanoxin), a me theophylline (Theo-24, Theochron, Theolair). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me propylthiouracil, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau ʻē aʻe āpau āu e lawe nei, ʻoiai inā ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa iā ʻoe ka leukopenia. nā hunaola ʻulaʻula, nā hunaola keʻokeʻo, a i ʻole nā ​​platelet; aiʻole ka maʻi ate.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i propylthiouracil, e kāhea i kāu kauka. Hiki i kāu kauka ke ʻōlelo aku iā ʻoe e lawe i ka propylthiouracil i nā mahina mua o kou hāpai ʻana a laila hoʻololi ʻoe iā ʻoe i ka methimazole no ke koena o kou hāpai ʻana. Hiki i ka Propylthiouracil ke kumu i nā pilikia o ke ake i nā wahine hāpai a hōʻeha paha i ka fetus.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i propylthiouracil.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Propylthiouracil i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • poho lauoho
  • pilikia i ka hoʻāʻo ʻana i ka meaʻai
  • numbness, puhi ʻana, a i ʻole ke kani ʻana o nā lima a me nā wāwae paha
  • ʻeha hui a ʻeha ʻeha paha
  • ʻūpā
  • pehu o ka ʻāʻī

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka:

  • ʻeha ka ʻāʻī, ke kuni, ke anu, ka ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
  • ʻeha poʻo
  • ʻeha ka ʻili, hives, pāhū, hū a ʻili paha
  • ʻeleʻele, popo-ʻeleʻele, ʻeleʻele a i ʻole mimi foamy
  • ka pehu o ka maka, ka maka, ka ʻōpū, ka lima, ka lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • ʻeha ka umauma
  • pōkole o ka hanu a i ʻole ke kani ʻana
  • kahe ana ke koko

Hoʻokumu paha ʻo Propylthiouracil i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

  • nausea
  • ka luaʻi
  • ʻeha ka ʻōpū
  • ʻeha poʻo
  • fiva
  • ʻeha pū
  • ʻūlili
  • ka pehu ʻana o nā lima, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • ʻeha ka ʻāʻī, ke kuni, ke anu, a me nā ʻōuli ʻē aʻe o ka maʻi
  • ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
  • ʻele a ʻili paha o ka ʻili
  • numbness, puhi ʻana a i ʻole ke kani ʻana o nā lima a me nā wāwae paha
  • melemele o ka ʻili a me nā maka
  • nalo ʻai ʻole
  • ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
  • ʻūlili
  • ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
  • luhi nui loa
  • nāwaliwali

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i propylthiouracil.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe.Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • ʻO Propycil
  • PTU

ʻAʻole kēia huahana māka i ka mākeke hou. Hiki ke loaʻa nā koho ʻē aʻe.

Nānā Hou - 07/15/2017

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