ʻO Doxorubicin

Anter

• Ma mua o ka loaʻa ʻana o ka injection doxorubicin,
• Hoʻokumu paha ʻo Doxorubicin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Pono e lawelawe ʻia ʻo Doxorubicin i kahi aa koko wale nō. Eia nō naʻe, e kulu paha i loko o nā mea a puni e hoʻonāukiuki a hōʻino paha. E nānā kāu kauka a kahu hānai paha i kāu pūnaewele hoʻomalu no kēia hopena. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ʻeha, ʻili, ʻulaʻula, pehu, pehu, a me nā ʻeha ma kahi o ka lāʻau i hōʻeha ʻia.

Hoʻokumu paha ʻo Doxorubicin i nā pilikia puʻuwai koʻikoʻi a hoʻoweliweli paha i kēlā me kēia manawa i ka wā o kāu mālama ʻana a i ʻole mau mahina i hala nā makahiki ma hope o ka pau ʻana o kāu lapaʻau. E kauoha kāu kauka i nā hoʻokolohua ma mua a i kāu wā e mālama ai e ʻike inā e hana pono ana kou puʻuwai iā ʻoe e loaʻa maluhia iā doxorubicin. Hiki i kēia mau hoʻāʻo ke hoʻopili i kahi electrocardiogram (ECG; hōʻike e hoʻopaʻa i ka hana uila o ka puʻuwai) a me kahi echocardiogram (hoʻāʻo e hoʻohana ana i nā nalu kani e ana i ka hiki i kou puʻuwai ke pauma i ke koko). E haʻi paha kāu kauka iā ʻoe ʻaʻole pono e loaʻa iā ʻoe kēia lāʻau inā loaʻa ka nui o ka puʻuwai o ka puʻuwai a i ʻole inā hōʻike nā hōʻike i ka hiki i kou puʻuwai ke pauma i ke koko. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa kekahi ʻano maʻi maʻi puʻuwai, kahi puʻuwai puʻuwai, a i ʻole radiation (x-ray) therapy i ka umauma. E haʻi i kāu kauka a me kāu kauka lāʻau inā ʻoe e lawe a loaʻa paha i kekahi mau lāʻau chemotherapy chemotherapy e like me cyclophosphamide (Cytoxan), daunorubicin (Cerubidine, DaunoXome), epirubicin (Ellence), idarubicin (Idamycin), mitoxantrone (Novantrone), paclitaxel (Abraxane, Onxol), trastuzumab (Herceptin), a i ʻole verapamil (Calan, Isoptin). Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ka pōkole o ka hanu; paʻakikī i ka hanu ʻana; ka pehu ʻana o nā lima, nā wāwae, nā kuʻekuʻe wāwae a i ʻole nā ​​wāwae lalo; a i ʻole wikiwiki, kūlike ʻole, a i ʻole kuʻi ka naʻau.

Hiki i ka Doxorubicin ke hoʻemi i ka nui o nā hunaola o ke kaola o kou iwi. E kauoha pinepine kāu kauka i nā hoʻokolohua hale hana ma mua a ma kāu mālama. ʻO ka hoʻemi ʻana i ka helu o nā hunaola koko i loko o kou kino e kumu i kekahi mau hōʻailona a hoʻonui paha i ka makaʻu e hoʻomohala ʻoe i kahi maʻi nui a i ʻole ke kahe ʻana o ke kahe. E haʻi i kāu kauka a me ka kauka inā ʻoe e lawe a loaʻa paha iā azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex), a i ʻole progesterone (Provera, Depo-Provera). Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ke kuni, ka ʻāʻī, ka ʻū a me ka paʻa mau, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi. kahe koko ʻole a ʻeha paha; koko a ʻeleʻele paha, noho humuhumu; luaʻi koko; a i ʻole ka luaʻi ʻana i ke koko a i ʻole nā ​​mea ʻeleʻele e like me ke kahua kope.

Hiki paha i ka Doxorubicin ke hoʻonui i kou makaʻu no ka hoʻomohala ʻana i ka leukemia (maʻi ʻaʻai o nā hunaola keʻokeʻo), keu hoʻi ke hāʻawi ʻia ia i nā koina kiʻekiʻe a i ʻole me nā lāʻau chemotherapy a me radiation (x-ray) therapy.

E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate. E haʻi paha kāu kauka iā ʻoe ʻaʻole pono e loaʻa iā ʻoe kēia lāʻau a hoʻololi paha i kāu lāʻau inā loaʻa ʻoe i ka maʻi ate.

Pono e hāʻawi ʻia ʻo Doxorubicin ma lalo o ka nānā ʻana a ke kauka me ka ʻike i ka hoʻohana ʻana i nā lāʻau chemotherapy.

Hoʻohana ʻia ʻo Doxorubicin me ka hoʻohui ʻia me nā lāʻau ʻē aʻe e mālama ai i kekahi ʻano o ka maʻi ʻaʻai, ka umauma, ka māmā, ka ʻōpū, a me ka maʻi ʻaʻai ovarian; Hodgkin's lymphoma (ka maʻi ʻo Hodgkin) a me ka lymphoma non-Hodgkin (maʻi ʻaʻai e hoʻomaka i nā hunaola o ka ʻōnaehana pale); a me kekahi mau ʻano leukemia (maʻi ʻaʻai o nā aʻa koko keʻokeʻo), e like me ka leukemia lymphoblastic huikau (ALL) a me ka leukemia myeloid nui (AML, ANLL). Hoʻohana wale ʻia ʻo Doxorubicin a i ka hui pū ʻana me nā lāʻau ʻē aʻe e mālama i kekahi ʻano o ka maʻi ʻaʻai thyroid a me kekahi ʻano o nā mea palupalu a i ʻole nā ​​sarcomas iwi (cancer that form in muscle and iwi). Hoʻohana ʻia ia e mālama i ka neuroblastoma (kahi maʻi ʻaʻai e hoʻomaka i nā pūnana nerve a hana nui ʻia i nā keiki) a me ka tumo Wilms (kahi ʻano maʻi ʻaʻai kolo e kū ana i nā keiki). Aia ʻo Doxorubicin i loko o ka papa o nā lāʻau i kapa ʻia he antracyclines. Hana ia ma ka hoʻolohi a hoʻopaʻa ʻana i ka ulu ʻana o nā hunaola maʻi ʻaʻai i loko o kou kino.

Hele mai ʻo Doxorubicin ma ke ʻano he hopena (wai) a i ʻole he pauka e kāwili ʻia me ka wai e hoʻokomo ʻiʻo ʻia (i loko o kahi aa) e ke kauka a kahu wahine paha i kahi wahi olakino. Hāʻawi pinepine ʻia kēlā me kēia 21 a 28 mau lā. Aia ka lōʻihi o ka mālama ʻana i nā ʻano lāʻau āu e lawe nei, pehea ka maikaʻi o ka pane ʻana o kou kino iā lākou, a me ke ʻano o ka maʻi ʻaʻai āu.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Hoʻohana ʻia ʻo Doxorubicin i kekahi manawa e mālama i ka maʻi ʻaʻai o ka pū, endometrium (ka uhi ʻana o ka uterus), a me ka cervix (ka wehe ʻana o ka uterus); maʻi ʻaʻai prostate (cancer of a male reproductive organ); maʻi ʻaʻai pancreatic; maʻi ʻaʻai adrenocortical (cancer i loko o nā adrenal gland); maʻi ʻaʻai ate; ʻO ka sarcoma a Kaposi e pili ana i ka loaʻa ʻana o ka maʻi immunodeficiency (AIDS); ʻO sarcoma a Ewing (kahi ʻano maʻi ʻaʻai iwi) i nā keiki; mesothelioma (maʻi ʻaʻai i ka pale o ka umauma a i ʻole ka ʻōpū); myeloma maha (kahi ʻano maʻi ʻaʻai o ka iwi iwi); a me ka leukemia lymphoblastic mau (CLL; kahi ʻano maʻi ʻaʻai o nā hunaola keokeo). E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka hoʻohana ʻana i kēia lāʻau no kou maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection doxorubicin,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka doxorubicin, daunorubicin (Cerubidine, DaunoXome), epirubicin (Ellence), idarubicin (Idamycin), nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka inxorubicin injection. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono i nā lāʻau i helu ʻia i ka ʻĀINA WAIWAI nui a me kekahi o kēia mau mea: kekahi mau lāʻau chemotherapy e like me cytarabine (DepoCyt), dexrazoxane (Zinecard), merc laptopurine (Purinethol), streptozocin (Zanosar); phenobarbital (Luminal Sodium); aiʻole phenytoin (Dilantin). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. E launa pū paha nā lāʻau ʻē aʻe me doxorubicin, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i nā lāʻau olakino ʻē aʻe.
• pono ʻoe e ʻike he pilikia paha ka doxorubicin i ka pōʻai menstrual maʻamau (manawa) i nā wahine a hoʻopau paha i ka hana sperm i nā kāne. Eia nō naʻe, ʻaʻole pono ʻoe e kuhi ʻaʻole hiki iā ʻoe ke hāpai a i ʻole hiki iā ʻoe ke hāpai i kekahi mea ʻē aʻe. ʻO nā wahine hāpai a hānai hānai paha e haʻi i kā lākou kauka ma mua o ka hoʻomaka ʻana i ka loaʻa ʻana o kēia lāʻau. ʻAʻole pono ʻoe e hāpai a i ʻole hānai umauma ke loaʻa ʻoe i ka inikū doxorubicin. Inā hāpai ʻoe i ka loaʻa ʻana o ka doxorubicin, e kāhea i kāu kauka. E hoʻohana i kahi ʻano pono o ka kaohi hānau e pale i ka hāpai ʻana. Hoʻopilikia paha ʻo Doxorubicin i ke fetus.
• ʻaʻohe o nā lāʻau āpau ke kamaʻilio ʻole ʻia me kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hoʻokumu paha ʻo Doxorubicin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• ʻeha ma ka waha a me ka puʻu
• lilo o ka makemake (a me ka pohō kaumaha)
• loaʻa kaupaona
• ʻeha ka ʻōpū
• pāhoehoe
• hoʻonui ka make wai
• luhi ʻole a nawaliwali paha
• ʻūpā
• poho lauoho
• ka hoʻokaʻawale ʻana o ka manamana a i ʻole nā ​​manamananui mai ka moe kui
• ʻili, ʻulaʻula, wai, a i ʻole nā ​​maka hoʻonāukiuki
• ʻeha ka maka
• ʻeha, puhi ʻana, a i ʻole ka ʻūlū ʻana i nā lima a me nā wāwae paha
• ʻulaʻula o ka mimi (no 1 a 2 mau lā ma hope o ka hopena)

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

• hives
• ʻāwīwī o ka ʻili
• ʻūlili
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana
• ka hopu ʻana

Hoʻokumu paha ʻo Doxorubicin i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻeha ma ka waha a me ka puʻu
• fiva, ʻeha ka ʻāʻī, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• kahe koko ʻole ʻana a palapū paha
• pahu noho ʻeleʻele a lohi hoʻi
• koko ʻulaʻula i nā noho
• luaʻi koko
• mea luaʻi e like me ke kahua kope

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua e nānā i ka pane o kou kino i doxorubicin.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Adriamycin^®¶
• Rubex^®¶

• ʻO Hydroxydaunomycin Hydrochloride
• Hydroxydoxorubicin Hydrochloride

^¶ ʻAʻole kēia huahana māka i ka mākeke hou. Hiki ke loaʻa nā koho ʻē aʻe.