Binimetinib

Anter

• Ma mua o ka lawe ʻana i binimetinib,
• Hoʻokumu paha ʻo Binimetinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

Hoʻohana ʻia ʻo Binimetinib me ka encorafenib (Braftovi) e mālama ai i kekahi ʻano melanoma (kahi ʻano maʻi ʻaʻai o ka ʻili) i pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a i ʻole hiki ke hemo ʻia e ka ʻoki kino. Aia ʻo Binimetinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i mea e hōʻoki a hoʻolohi ai paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Binimetinib ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia me ka ʻai ʻole a ʻelua mau meaʻai i kēlā me kēia lā, ma kahi o 12 mau hola ke kaʻawale. Lawe i ka binimetinib ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka binimetinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka lāʻau, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

E hoʻemi paha kāu kauka a i ʻole no ka manawa kūloko a paʻa mau paha i kāu mālama ʻana inā e ʻike ʻoe i nā hopena ʻaoʻao. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me binimetinib.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i binimetinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka binimetinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa binimetinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, lawe ʻoe a hoʻolālā paha e lawe. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe ka maʻi puʻuwai a i ʻole ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau. Pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kāu mālama ʻana me binimetinib a no 30 mau lā ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana o ka kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i binimetinib, e kāhea koke i kāu kauka. Hiki paha iā Binimetinib ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka wā e lawe ana ʻoe i ka binimetinib a no 3 mau lā ma hope o kāu hopena hope loa.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā aia i loko o 6 mau hola o ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Binimetinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• luhi
• nausea
• pāhoehoe
• ka luaʻi
• abdominal eha
• kōpaʻa
• ʻūpā

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• loli ka hihiʻo a ʻeha paha ka maka, pehu, a ʻulaʻula paha
• fiva, ʻeha puʻu, ʻalalā, ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• melemele nā ​​maka a i ʻole ka ʻili, mimi ʻeleʻele, nalo o ka makemake ʻole, luhi, a ʻeha a ʻoluʻolu ʻole paha ma ka ʻaoʻao ʻōpū o luna pono
• nāwaliwali kūikawā, ʻehaʻeha o ka mākala, a i ʻole ka mimi ʻulaʻula a ʻeleʻele paha
• kahe koko ʻole a ʻeha paha; ʻeleʻele, hoʻoluhi, a i ʻole nā ​​noho koko; a i ʻole ke kaʻe ʻana i ke koko
• pōkole o ka hanu a me ke kahe
• hoʻomaka koke o ka paʻakikī hanu; ʻeha ka umauma; ka pehu ʻana o nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo; aiʻole kaʻeha o ka wāwae, ka mahana, a me ka pupuhi
• wikiwiki, kuʻi ka naʻau; pokole o ka hanu; pehu o nā kuʻekuʻe wāwae a me nā wāwae; a luʻuluʻu paha

Hoʻokumu paha ʻo Binimetinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mālama i nā manawa a pau me kāu kauka, kauka maka, a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab, me nā hoʻokolohua maka, e nānā i ka pane o kou kino i binimetinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Mektovi^®