Pomalidomide

Anter

• Ma mua o ka lawe ʻana i ka pomalidomide,
• Hoʻokumu paha ʻo Pomalidomide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo AOAO IMĀKAHI a i ʻole nā ​​WAIKAHI HOU, e hoʻōki i ka lawe ʻana i ka pomalidomide a kāhea koke aku i kāu kauka:

ʻO ka makaʻu i nā kīnā hānau hānau weliweli a weliweli hoʻi i hoʻokumu ʻia e pomalidomide.

No nā mea maʻi āpau e lawe ana i ka pomalidomide:

ʻAʻole pono e lawe ʻia ʻo Pomalidomide e nā mea maʻi e hāpai a hāpai paha. Aia kahi makaʻu nui e hiki i ka pomalidomide ke lilo i ka hāpai ʻana a i ʻole e hoʻokumu ʻia ka pēpē me nā kīnā hānau (nā pilikia e kū nei ma ka wā hānau).

ʻO kahi papahana i kapa ʻia ʻo Pomalyst REMS^® ua hoʻonohonoho ʻia e hōʻoia i ka lawe ʻole ʻana o nā wahine hāpai i ka pomalidomide a ʻaʻole hāpai nā wahine i ka wā e lawe ana i ka pomalidomide. ʻO nā mea maʻi āpau, e like me nā wahine i hiki ʻole ke hāpai a me nā kāne, hiki ke loaʻa pomalidomide wale nō inā hoʻopaʻa inoa ʻia lākou me Pomalyst REMS^®, loaʻa kahi palapala mai ke kauka i hoʻopaʻa inoa ʻia me Pomalyst REMS^®, a hoʻopiha i ke kuhikuhi ma kahi kauka lāʻau i hoʻopaʻa inoa ʻia me Pomalyst REMS^®.

E loaʻa iā ʻoe ka ʻike e pili ana i ka makaʻu o ka lawe ʻana i ka pomalidomide a pono ʻoe e kau inoa i kahi palapala ʻae i hoʻomaopopo ʻia e hōʻike ana ua maopopo iā ʻoe kēia ʻike ma mua o ka loaʻa ʻana o ka lāʻau. Pono ʻoe e ʻike i kāu kauka i kou wā e lapaʻau ai e kamaʻilio e pili ana i kou ʻano a me nā hopena ʻē aʻe āu e ʻike nei a i ʻole nā ​​hoʻokolohua hāpai e like me ka ʻōlelo a ka papahana.

E haʻi i kāu kauka inā ʻaʻole ʻoe e maopopo i nā mea āpau āu i haʻi ʻia ai e pili ana i ka pomalidomide a me ka Pomalyst REMS^® polokalamu a pehea e hoʻohana ai i nā ʻano hana hānau i kūkākūkā ʻia me kāu kauka, a i ʻole inā ʻaʻole ʻoe e manaʻo hiki iā ʻoe ke mālama i nā wā i hoʻopaʻa ʻia.

Mai hāʻawi i ke koko i ka wā e lawe ana ʻoe i ka pomalidomide a no 4 mau pule ma hope o kāu lapaʻau ʻana.

Mai hoʻokaʻawale i ka pomalidomide me kekahi mea ʻē aʻe, ʻoiai kekahi i loaʻa nā hōʻailona like me ʻoe.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka pepa ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me pomalidomide a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole http://www.celgeneriskmanagement.com e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i nā makaʻu o ka lawe ʻana i ka pomalidomide.

No nā mea maʻi wahine e lawe ana i ka pomalidomide:

Inā hiki iā ʻoe ke hāpai, pono ʻoe e hoʻokō i kekahi mau koi i ka wā o kāu mālama ʻana me pomalidomide. Pono ʻoe e hoʻokō i kēia mau koi inā loaʻa iā ʻoe kahi tubigation ligation ('tubes i hoʻopaʻa ʻia,' ʻoki e pale ai i ka hāpai keiki). E kala ʻia ʻoe mai ka hālāwai ʻana i kēia mau koi inā ʻaʻole ʻoe i menstruated no 24 mau mahina i ka lālani a ʻōlelo mai kāu kauka ua hala ʻoe i ka menopause ('hoʻololi o ke ola') a i ʻole ua ʻoki ʻia ʻoe e wehe i kou uterus a me / a i ʻole nā ​​ovaries ʻelua. Inā ʻaʻole pololei kekahi o kēia mau mea iā ʻoe, a laila pono ʻoe e hoʻokō i nā koina ma lalo.

Pono ʻoe e hoʻohana i ʻelua mau ʻano ʻoluʻolu o ka ka hānau hānau ʻana no 4 mau pule ma mua o kou hoʻomaka ʻana e lawe i ka pomalidomide, i kou wā e mālama ai, e like me nā manawa a ke kauka e ʻōlelo ai iā ʻoe e hoʻoki iki i ka lawe ʻana i ka pomalidomide, a no 4 mau pule ma hope o kāu lapaʻau ʻana. E haʻi aku kāu kauka iā ʻoe i ke ʻano o ka kaohi hānau e ʻae ʻia a e hāʻawi iā ʻoe i ka ʻike kākau e pili ana i ka kaohi hānau. Pono ʻoe e hoʻohana i kēia ʻano ʻelua o ka kaohi hānau i nā manawa āpau ke ʻole ʻoe e hoʻohiki ʻaʻole ʻoe e moe kolohe me kahi kāne no 4 mau pule ma mua o kou lapaʻau ʻana, i kāu wā e hoʻomaʻamaʻa ai, i nā wā e hoʻopau ʻia ai kāu lapaʻau ʻana, a no 4 mau pule ma hope kāu lapaʻau ʻana.

Inā koho ʻoe e lawe i ka pomalidomide, he kuleana kou e hōʻalo i ka hāpai ʻana no 4 mau pule ma mua, i ka wā, a no 4 mau pule ma hope o kāu lapaʻau ʻana. Pono ʻoe e hoʻomaopopo he hiki ʻole i kekahi ʻano ke kāohi hānau. No laila, he mea nui loa e hoʻēmi i ka makaʻu o ka hāpai ʻole ʻana ma o ka hoʻohana ʻana i ʻelua ʻano o ka kaohi hānau. E haʻi i kāu kauka inā ʻaʻole ʻoe e maopopo i nā mea āpau āu i haʻi ʻia ai e pili ana i ka kaohi hānau a i ʻole manaʻo ʻoe hiki iā ʻoe ke hoʻohana i ʻelua ʻano o ka kaohi hānau i nā manawa āpau.

Pono ʻoe i ʻelua mau hoʻokolohua maikaʻi ʻole o ka hāpai ma mua o ka hiki iā ʻoe ke hoʻomaka e lawe i ka pomalidomide. Pono ʻoe e hoʻāʻo ʻia no ka hāpai ʻana i loko o kahi keʻena hoʻokolohua i kekahi mau manawa i kāu mālama ʻana. E haʻi aku kāu kauka iā ʻoe i ka manawa a me kahi e loaʻa ai kēia mau hoʻokolohua.

E hōʻoki i ka lawe ʻana i ka pomalidomide a kāhea koke aku i kāu kauka inā manaʻo ʻoe he hāpai ʻoe, ua hala ʻoe i kahi wā menstrual, a i ʻole he moe kolohe ʻoe me ka hoʻohana ʻole ʻana i ʻelua ʻano o ka kaohi hānau. Inā hāpai ʻoe i ka wā o kāu mālama ʻana a i ʻole ma loko o 30 mau lā ma hope o kāu mālama ʻana, e kāhea ke kauka i ka Pomalyst REMS^® polokalamu, ka mea hana pomalidomide, a me ka Food and Drug Administration (FDA).

No nā mea maʻi kāne e lawe ana i ka pomalidomide:

Aia ʻo Pomalidomide i ka semen (ka wai i loaʻa ka sperm i hoʻokuʻu ʻia ma o ka peni i ka manawa o ka orgasm). Pono ʻoe e hoʻohana i ka latex a i ʻole syntom synthetic, ʻoiai inā he vasectomy kāu (ʻoki kino e pale ai i ke kāne mai ka hāpai ʻana), i kēlā me kēia manawa ke moe kolohe ʻoe me kahi wahine hāpai a i hiki ke hāpai i ka wā e lawe ana ʻoe i ka pomalidomide a no 28 mau lā ma hope o kāu lapaʻau. E haʻi aku i kāu kauka inā he moe kolohe ʻoe me ka wahine me ka hoʻohana ʻole ʻana i ka condom a i ʻole inā manaʻo paha kāu pakanā he hāpai paha ʻo ia i kāu wā lapaʻau me pomalidomide.

Mai hāʻawi i ka sperm ʻoiai ʻoe e lawe ana i ka pomalidomide a no 4 mau pule ma hope o kāu lapaʻau.

Pilikia o ke koko clots:

Inā ʻoe e lawe i ka pomalidomide e mālama i ka myeloma maha (kahi ʻano maʻi ʻaʻai o ka iwi iwi), aia kahi makaʻu e hoʻomohala ʻoe i ka puʻuwai puʻuwai, kahi hahau ʻana, a i ʻole ke koko i kou wāwae (deep vein thrombosis; DVT) kēlā neʻe paha i loko o ke kahawai i kou mau māmā (pulmonary embolism, PE). E haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi puʻuwai a i ʻole hahau. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka pomalidomide. E haʻi pū aku i kāu kauka inā puhi ʻoe a hoʻohana paha i ka paka, inā ua loaʻa ʻoe i ka puʻuwai puʻuwai a i ʻole hahau ʻana, a inā loaʻa iā ʻoe a i ʻole loaʻa i ke koko kiʻekiʻe, a i ʻole nā ​​kiʻekiʻe o ke koko a me nā momona, hiki i kāu kauka ke kuhikuhi i nā lāʻau ʻē aʻe i lawe pū ʻia me pomalidomide e hōʻemi i kēia pilikia. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope o ka lawe ʻana i ka pomalidomide, e haʻi koke aku i kāu kauka: ʻeha ke poʻo loa; ka luaʻi; nā pilikia ʻōlelo; ʻino a maʻule paha; pohihihi piha o ka hihiʻo; ka nāwaliwali a i ʻole ka helu ʻana o ka lima a me ka wāwae; ʻeha o ka umauma e pālahalaha aʻe i nā lima, ka ʻāʻī, ʻāʻī, kua, a ʻōpū paha; pokole o ka hanu; huikau; aiʻole kaʻeha, ka pehu, a me kaʻulaʻula i ka wāwae hoʻokahi.

E kamaʻilio me kāu kauka e pili ana i nā makaʻu o ka lawe ʻana i ka pomalidomide.

Hoʻohana ʻia ʻo Pomalidomide me ka dexamethasone e mālama ai i ka myeloma he nui (kahi ʻano maʻi ʻaʻai o ka iwi iwi) ʻaʻole i hoʻomaikaʻi ʻia i loko a i ʻole ma loko o 60 mau lā o ka mālama ʻana me ʻelua mau lāʻau ʻē aʻe, e like me ka lenalidomide (Revlimid) a me kahi mea hoʻohiwahiwa proteasome e like me bortezomib (Velcade) a i ʻole carfilzomib (Kyprolis). Hoʻohana ʻia ia e mālama i ka sarcoma a Kaposi (kahi ʻano o ka maʻi ʻaʻai e ulu ai nā aʻa ʻokoʻa ma nā ʻāpana like ʻole o ke kino) e pili ana i ka loaʻa ʻana o ka maʻi maʻi maʻi (AIDS) ma hope o ka hana kūleʻa ʻole ʻia me nā lāʻau ʻē aʻe a i ʻole ka poʻe me ka sarcoma a Kaposi ʻaʻole. Loaʻa i ka maʻi maʻi maʻi maʻi (HIV) kanaka. Aia ʻo Pomalidomide i loko o ka papa o nā lāʻau i kapa ʻia he mau mea pale maʻi. Hana ia ma ke kōkua ʻana i ka iwi iwi e hana i nā hunaola kūlohelohe a me ka luku ʻana i nā hunaola kūpono ʻole i ka iwi iwi.

Hele mai ʻo Pomalidomide ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā me ka ʻole o ka meaʻai i nā lā 1 a 21 o kahi pōʻaiapuni 28 mau lā. E hana hou paha kēia ʻano 28 lā e like me ka ʻōlelo a kāu kauka. Lawe iā pomalidomide ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka pomalidomide. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā capsule a pau i ka wai; mai haki a nau iā lākou. Mai wehe i nā capsule a lawelawe iā lākou ma mua o ka pono. Inā pili kou ʻili me nā capsule naha a i ʻole ka pauka, holoi i kahi i hōʻike ʻia me ke kopa a me ka wai. Inā loaʻa kekahi mau mea o ka capsule i kou mau maka, holoi koke i kou mau maka me ka wai.

Pono paha kāu kauka e hoʻokū paʻa a i ʻole no ka manawa pōkole i kāu mālama ʻana a hōʻemi paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E hoʻomaopopo pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me pomalidomide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka pomalidomide,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka pomalidomide, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsule pomalidomide. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: carbamazepine (Carbatrol, Tegretol, Teril, a me nā mea ʻē aʻe); ciprofloxacin (Cipro); fluvoxamine (Luvox); a me ketoconazole (Nizoral). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me pomalidomide, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa iā ʻoe ka dialysis (lapaʻau lapaʻau e hoʻomaʻemaʻe i ke koko ke hana ʻole nā ​​puʻupaʻa) a i ʻole loaʻa i ka maʻi ate.
• mai hānai umauma ʻoiai ʻoe e lawe ana i ka pomalidomide.
• e haʻi i kāu kauka inā hoʻohana ʻoe i nā huahana paka. Hiki i ka uahi paka ʻana ke hōʻemi i ka pono o kēia lāʻau.
• pono ʻoe e ʻike i ka pomalidomide e hoʻohoka a huikau paha ʻoe. Mai hoʻokele i kahi kaʻa, hana i nā mīkini, a hana i nā hana ʻē aʻe e koi iā ʻoe e makaʻala a hiki i kou ʻike ʻana i ka hopena o kēia lāʻau iā ʻoe.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā he emi ia ma mua o 12 mau hola a hiki i kāu kau palena hope e hoʻolālā ʻia, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Pomalidomide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• kōpaʻa
• pāhoehoe
• nausea
• ka luaʻi
• nalo ʻai ʻole
• loli ke kaupaona
• luliluli ʻole ʻana i kahi ʻāpana o ke kino
• ka hou sweating a i ʻole ka weluwelu po
• hopohopo
• ʻili maloʻo
• ka pehu ʻana o nā lima, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a i nā wāwae lalo
• ami, mākala, a i ʻole ʻehaʻeha
• pilikia e hiamoe ana a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo AOAO IMĀKAHI a i ʻole nā ​​WAIKAHI HOU, e hoʻōki i ka lawe ʻana i ka pomalidomide a kāhea koke aku i kāu kauka:

• hūwī
• ʻūlili
• hives
• ʻili a ʻili hoʻi i ka ʻili
• ka pehu o nā maka, ka maka, ke elelo, ka ʻāʻī, nā lima, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana
• hulahula
• fiva, ʻeha puʻu, ʻalalā, ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• melemele nā ​​maka a i ʻole ka ʻili
• mimi ʻeleʻele
• ʻeha a hōʻoluʻolu ʻole paha ma ka ʻaoʻao ʻōpū o luna pono
• paʻakikī, pinepine, a i ʻole urination ʻeha
• ʻili mae
• luhi ʻole a nawaliwali paha
• kahe koko ʻole ʻana a palapū paha
• ihu ihu
• numbness, puhi ʻana, a i ʻole ka ʻūlū ʻana i nā lima a me nā wāwae paha
• ka hopu ʻana

Hiki i ka Pomalidomide ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i nā maʻi ʻē aʻe E kamaʻilio me kāu kauka e pili ana i nā makaʻu o ka lawe ʻana i ka pomalidomide.

Hoʻokumu paha ʻo Pomalidomide i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi.E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. E hoʻihoʻi i nā lāʻau i pono ʻole i kāu kauka lāʻau a i ʻole ka mea hana. E nīnau i kāu kauka lāʻau inā he nīnau kāu e pili ana i ka hoʻihoʻi ʻana i kāu lāʻau.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka pomalidomide.

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Pomalyst^®