Testosteroma
Hoʻopili kahi hōʻike testosterone i ka nui o ka hōmona kāne, testosterone, i loko o ke koko. Hana nā kāne a me nā wahine i kēia hōmona.
ʻO ke hōʻike i ho'ākāka ʻia ma kēia ʻatikala e ana i ka nui o ka testosterone i loko o ke koko. ʻO ka hapa nui o ka testosterone i loko o ke koko e paʻa i kahi protein i kapa ʻia ʻo ka sex hormone binding globulin (SHBG). Hiki i kekahi hōʻoia koko ke ana i ka testosterone "manuahi". Eia nō naʻe, ʻaʻole pololei loa kēia ʻano hoʻāʻo.
Lawe ʻia kahi laʻana koko mai kahi aa koko. ʻO ka manawa kūpono no ka laʻana koko e lawe ʻia ma waena o 7 a 10 mau kakahiaka. Pono ʻia kahi lua o ka laʻana e hōʻoia i kahi hopena ma lalo o ka mea i manaʻo ʻia.
E ʻōlelo paha ka mea mālama ola iā ʻoe e haʻalele i ka lawe ʻana i nā lāʻau i hiki ke hoʻololi i ka hōʻike.
ʻIke paha ʻoe i kahi ʻōniuʻuʻuʻu a kuʻi paha ke hoʻokomo ʻia ka nila. E hāwele ana paha ma hope.
Hiki ke hana i kēia hōʻoia inā loaʻa iā ʻoe nā ʻōuli o ka hana male kāne (androgen) hana.
I nā kāne, hana ka testicle i ka hapa nui o ka testosterone i ke kino. Nānā pinepine ʻia nā pae e loiloi i nā hōʻailona o ka testosterone pono ʻole e like me:
- ʻO ka wā ʻōpio a i ʻole wā ʻōpio (i ke keikikāne)
- Infertility, erectile hana, haʻahaʻa pae o ka moekolohe hoihoi, lahilahi o nā iwi (i nā kāne)
I nā wahine, hoʻopuka nā ovaries i ka hapa nui o ka testosterone. Hiki i nā momona adrenal ke hana i nā androgens ʻē aʻe i hoʻohuli ʻia i testosterone. Nānā pinepine ʻia nā pae e loiloi i nā hōʻailona o nā pae testosterone kiʻekiʻe, e like me:
- Huehue, ʻili ʻaila
- Hoʻololi i ka leo
- Hoemi i ka nui o ka umauma
- ʻO ka ulu ʻana o ka lauoho (pouli, lauoho huluhulu i kahi o ka ʻumiʻumi, ʻumiʻumi, ʻaoʻao, umauma, ʻūhā, ʻūhā o loko)
- Hoʻonui i ka nui o ka clitoris
- Nā wā maʻa mau a i ʻole haule
- ʻŌhule ʻaʻano kāne a lahilahi paha
Nā ana maʻamau no kēia mau hoʻāʻo:
- Kāne: 300 i ka 1,000 nanograms ma kēlā me kēia deciliter (ng / dL) a i ʻole 10 a 35 nanomoles i kēlā me kēia lita (nmol / L)
- Wahine: 15 a 70 ng / dL a i ʻole 0.5 a 2.4 nmol / L
ʻO nā laʻana ma luna he ana maʻamau no nā hopena no kēia mau hoʻāʻo. Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā hoʻāʻo i nā mea hoʻohālikelike like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.
ʻO kekahi mau kūlana olakino, nā lāʻau, a i ʻole ka ʻeha hiki ke alakaʻi i ka testosterone haʻahaʻa. E hāʻule kūlohelohe hoʻi ka pae testosterone me ka makahiki. Hiki i ka testosterone haʻahaʻa ke hoʻopili i ka hoʻokele wahine, ka naʻau, a me ka nui o nā mākala i nā kāne.
ʻO ka emi ʻana o ka testosterone ma muli o:
- Maʻi maʻi maʻi
- ʻAʻole hana ka pituitary gland i nā nui maʻamau o kekahi a i ʻole nā mea āpau āpau
- Ka pilikia me nā wahi o ka lolo e kaohi ana i nā homone (hypothalamus)
- ʻO ka hana thyroid haʻahaʻa
- Hoopaneeia ka manawa makua
- Nā maʻi o nā testicle (trauma, cancer, maʻi maʻi, immune, iron overload)
- ʻO ka tumo Benign o nā hunaola pituitary e hana i ka nui o ka hormone prolactin
- Nui loa ka momona o ke kino (momona)
- Nā pilikia o ka hiamoe
- ʻO ke koʻikoʻi koʻikoʻi mai ka hoʻoikaika nui ʻana (overtraining Syndrome)
Hoʻonui ʻia paha ka pae testosterone ma muli o:
- Ke kūpaʻa i ka hana o nā kāne kāne (androgen resistence)
- Tumor o nā ovaries
- Ka maʻi ʻaʻai o nā testes
- ʻO hyperplasia adrenal congenital
- Lawe i nā lāʻau a i ʻole nā lāʻau e hoʻonui ai i ka pae testosterone (me kahi mau mea hoʻopili)
Testosterone serum
ʻO Rey RA, ʻo Josso N. Diagnosis a me ka mālama ʻana i nā maʻi o ka ulu moekolohe. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 119.
ʻO Rosenfield RL, Barnes RB, Ehrmann DA. ʻO Hyperandrogenism, hirsutism, a me polycystic ovary syndrome. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 133.
Swerdloff RS, Wang C. ʻO nā hōʻike a me nā kāne hypogonadism, infertility, a me ka moe kolohe. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 221.