Mea Kākau: Gregory Harris
Lā O Ka Hana: 8 Apelila 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
Linezolid (Oxazolidinone Antibiotic) - Mechanism of Action, Indications, and Side Effects
Wikiō: Linezolid (Oxazolidinone Antibiotic) - Mechanism of Action, Indications, and Side Effects

Anter

Hoʻohana ʻia ʻo Linezolid e mālama i nā maʻi, e like me ka niumonia, a me nā maʻi o ka ʻili. Aia ʻo Linezolid i kahi papa o nā antibacterial i kapa ʻia ʻo oxazolidinones. Hana ia ma ka hoʻōki ʻana i ka ulu ʻana o nā bacteria.

ʻAʻole holo nā Antibiotics e like me linezolid no nā anu, flu, a me nā maʻi viral ʻē aʻe. ʻO ka hoʻohana ʻana i nā lāʻau ʻaloʻalo ke pono ʻole lākou e hoʻonui i kou makaʻu i ka loaʻa ʻana o ka maʻi i hope e kū kūʻē ʻana i ka lāʻau antibiotic.

Hele mai ʻo Linezolid ma ke ʻano he papaha a hoʻokuʻu ʻia ka waha (wai) e lawe ma ka waha. Lawe ʻia ia me ka ʻai ʻole a ʻelua mau manawa o ka lā (i kēlā me kēia 12 hola) no 10 a 28 mau lā. Lawe pinepine nā kamaliʻi 11 mau makahiki a ʻoi paha i ka linezolid me ka ʻole o ka meaʻai ʻelua a ʻekolu mau manawa i ka lā (i kēlā me kēia 8 a 12 mau hola) no 10 a 28 mau lā. Aia ka lōʻihi o kāu mālama ʻana i ke ʻano o ka maʻi i loaʻa iā ʻoe. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei iā linezolid e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


Ma mua o ka hoʻohana ʻana i ka hoʻopaneʻe waha, e kāwili mālie iā ia ma ka hoʻohuli ʻana i ka ʻōmole ʻekolu a ʻelima mau manawa. Mai hoʻoluliluli i ke kau ʻana.

E lawe i ka linezolid a hiki i kou hoʻopau ʻana i ke kuhikuhi, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi. Mai hōʻoki i ka lawe ʻana i ka linezolid me ka walaʻau ʻole ʻana me kāu kauka. Inā kū ʻoe i ka lawe ʻana i ka linezolid a i ʻole ʻoki koke ʻoe i nā lāʻau, ʻaʻole hiki ke mālama pono ʻia i kāu maʻi a hiki i ke kūpikipiki ke kūʻē i nā antibiotic.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i linezolid,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka linezolid, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i ka huahana linezolid i kuhikuhi ʻia iā ʻoe. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā e lawe nei ʻoe i nā lāʻau aʻe a i ʻole ua oki ka lawe ʻana iā lākou i loko o nā pule ʻelua i hala: isocarboxazid (Marplan) phenelzine (Nardil). rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), a me tranylcypromine (Parnate). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka linezolid inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau, a i ʻole lawe ʻia i loko o nā pule ʻelua i hala.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i kekahi o kēia mau mea: epinephrine (EpiPen); meperidine (Demerol); nā lāʻau no ka migraine e like me almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), a me zolmitriptan (Zomig); phenylpropanolamine (ʻaʻole loaʻa hou ma ka US); a me pseudoephedrine (Sudafed; i nā lāʻau anuanu a decongestant paha). E haʻi pū aku i kāu kauka inā e lawe nei ʻoe i nā lāʻau aʻe a i ʻole ua oki ʻoe i ka lawe ʻana iā lākou i loko o ʻelua mau pule i hala iho nei: bupropion (Aplenzin, Wellbutrin, Zyban, nā mea ʻē aʻe); buspirone; nā mea hoʻoliʻiliʻi serotonin reuptake (SSRI) e like me citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), sertraline (Zoloft), a me vilazodone (Vilbyrd); serotonin norepinephrine reuptake inhibitors (SNRIs) e like me desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), a me venlafaxine (Effexor); a me nā antidepressants tricyclic e like me amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), a me trimipramine (Surmontil). E haʻi aku i kāu kauka inā lawe ʻoe i fluoxetine (Prozac, Sarafem, Selfemra, ma Symbyax), a i ʻole ua oki paha ka lawe ʻana i loko o nā pule he 5 i hala. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Pili pū paha nā lāʻau ʻē aʻe he nui me linezolid, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka inā loaʻa ʻoe i kahi maʻi mau (lōʻihi), a i ʻole inā loaʻa a loaʻa paha iā ʻoe ka maʻi maʻi carcinoid (kahi ʻano e hūnā ai kahi tumo i ka serotonin). ka maʻi diabetes, ke koko kiʻekiʻe, hyperthyroidism (kahi thyroid overactive), kaohi pale (nā pilikia me kāu ʻōnaehana pale), pheochromocytoma (kahi tumo o ka adrenal gland), ka hopu ʻana, a i ʻole nā ​​maʻi puʻupaʻa.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i linezolid, kāhea i kāu kauka.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha ʻoe e lawe ana i ka linezolid.
  • inā loaʻa iā ʻoe ka phenylketonuria (PKU, kahi ʻano hoʻoilina e pono ai e ukali ʻia kahi papaʻai kūikawā e pale ai i ka noʻonoʻo ʻole o ka noʻonoʻo), pono ʻoe e ʻike he ʻāpana aspartame e hana phenylalanine ka hoʻopōkole waha.

Hōʻalo i ka ʻai ʻana a i ʻole ka inu ʻana i nā meaʻai he nui a me nā mea inu me ka Tyramine i ka wā e lawe ana i ka linezolid. ʻO nā meaʻai a me nā mea inu i ʻohi ʻia, puhi ʻia, a hū ʻia paha i loko o ka tyramine. ʻO kēia mau meaʻai a me nā mea inu me nā mea inu ʻona, ʻoi aku ka pia, Chianti, a me nā waina ʻulaʻula ʻē aʻe. pia pia ʻole; nā paʻi waiū (ʻoi aku ka ikaika, ʻelemakule, a i ʻole nā ​​ʻano hana). sauerkraut; yogurt; huawaina; maiʻa; kaʻaila kawa; pickled herring; ate (ʻo ke ake moa ka moa); nāʻiʻo maloʻo a me ka sausage (me nā salami paʻakikī a me ka pepperoni); fiku kēpau; avocados; ʻiʻo kolo; Kuleke; nā mea hū hū; nā huahana papaya (me kekahi mau mea hoʻoulu ʻai); pīni fava; a me nā hua kī.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Linezolid ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • pāhoehoe
  • ʻeha poʻo
  • nausea
  • ka luaʻi
  • ʻeha ka ʻōpū
  • hoʻololi i ke ʻano o ka ʻono o nā mea
  • hūwī
  • ʻūlili
  • ʻūpā
  • ʻāpana keʻokeʻo i ka waha
  • ka huhū, ka wela ʻana a i ʻole ka ʻeha ʻana o ka ʻōpū
  • hoʻololi i ke kala o ke alelo a i ʻole nā ​​niho

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • hives, ʻāwīwī, ʻili, paʻakikī i ka hanu ʻana a me ka ale ʻana paha, ka pehu ʻana o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae i lalo, ke kani
  • ʻili a ʻiliʻili paha
  • nausea hou a me ka luaʻi; hanu wikiwiki; huikau; luhi nei
  • ʻeha, numbness, a nāwaliwali paha i nā lima, nā wāwae, a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino
  • diarrhea nui (ka wai a i ʻole nā ​​kūpuna koko) e kū mai me ka ʻole o ke kuni a me nā ʻōpū o ka ʻōpū (hiki i 2 mau mahina a ʻoi paha ma hope o kāu lapaʻau ʻana)
  • kahe koko ʻole ʻana a palapū paha
  • nā hoʻololi i ka hihi kala, ʻike i ka blur, a i ʻole nā ​​hoʻololi ʻē aʻe i ka hihiʻo
  • ka hopu ʻana

Hiki i Linezolid ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela a mai ka mālamalama a me ka nui o ka wela a me ka makū (ʻaʻole i loko o ka lua. Pono e hoʻohana ʻia ka hoʻokuʻu waha ʻo Linezolid ma waena o 21 mau lā.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help.Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. Kauoha paha kāu kauka i kekahi mau hoʻokolohua koko e nānā i ka pane o kou kino i linezolid.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. ʻAʻole hiki ke hoʻopiha hou ʻia kāu palapala kuhikuhi. Inā loaʻa iā ʻoe nā ʻōuli o ka maʻi ma hope o kou hoʻopau ʻana i ka linezolid, e kāhea i kāu kauka.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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