Antimitochondrial antibody

ʻO nā antimitochondrial antibodies (AMA) nā mea (antibodies) i kū kūʻē iā mitochondria. ʻO ka mitochondria kahi ʻāpana nui o nā hunaola. ʻO lākou ke kumu ikehu i loko o nā hunaola. Kōkua kēia mau mea i ka hana ʻana o nā pūnaewele.

Kūkākūkā kēia ʻatikala i ka hoʻokolohua koko i hoʻohana ʻia e ana i ka nui o ka AMA i loko o ke koko.

Pono kahi laʻana koko. Lawe pinepine ʻia ia mai kahi aa. Kapa ʻia ke kaʻina hana he venipuncture.

E ʻōlelo paha kāu mea mālama ola iā ʻoe ʻaʻole e ʻai a inu paha i kekahi mea a hiki i 6 mau hola ma mua o ka hoʻāʻo.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻO ka manaʻo ʻē aʻe wale nō he prick a i ʻole sensation stinging paha. Ma hope, aia paha kekahi ʻōkā.

Pono ʻoe i kēia hōʻoia inā loaʻa iā ʻoe nā hōʻailona hōʻino o ke ake. Hoʻohana pinepine ʻia kēia ho'āʻo e hōʻoia i ka cholangitis biliary mua, i kapa ʻia ma mua he bilier cirrhosis (PBC).

Hiki ke hoʻohana ʻia ka hoʻokolohua e haʻi ai i ka ʻokoʻa ma waena o ka ʻōnaehana bile cirrhosis a me nā pilikia o ke akepaʻa ma muli o nā kumu ʻē aʻe e like me ka blockage, viral hepatitis, a i ʻole cirrhosis ʻona.

ʻO ka maʻamau, ʻaʻohe mea ʻino i kēia manawa.

He mea nui kēia hōʻike no ke kuhi ʻana i ka PBC. ʻAneʻane ʻo nā poʻe āpau me ka maʻi e hoʻāʻo maikaʻi. Kākaʻikahi ka loaʻa ʻana o ka hopena maikaʻi i ke kanaka me ka ʻole o ke ʻano. Eia nō naʻe, hiki i kekahi poʻe me kahi hōʻoia maikaʻi no AMA a ʻaʻohe hōʻailona ʻē aʻe o ka maʻi ate e holo i PBC i ka hala ʻana o ka manawa.

Kākaʻikahi wale nō, e ʻike ʻia kekahi mau hopena maikaʻi ʻole ma muli o nā ʻano ʻano maʻi ate a me kekahi mau maʻi autoimmune.

ʻO nā pōʻino no ke kaʻi ʻana i ke koko he liʻiliʻi akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

• Hōʻaʻo koko

ʻO Beuers U, Gershwin ME, Gish RG, et al. Ke hoʻololi nei i ka nomenclature no PBC: Mai ka 'cirrhosis' a i ka 'cholangitis'. ʻO Clin Res Hepatol Gastroenterol. 2015; 39 (5): e57-e59. PMID: 26433440 www.ncbi.nlm.nih.gov/pubmed/26433440.

Chernecky CC, Berger BJ. A. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 84-180.

ʻO Eaton JE, Lindor KD. ʻO ka cirrhosis biliary mua. I: Feldman M, Friedman LS, Brandt LJ, eds. ʻO Sleisenger a me Fordtran's Gastrointestinal a me ka maʻi Liver: Pathophysiology / Diagnosis / Management. 10 o ka lā. Piladelapia, PA: Elsevier Saunders; 2016: chap 91.

ʻO Kakar S. cholangitis biliary maʻamau. I: Saxena R, ed. ʻO ke ʻano Hepatic Pathology: kahi ala diagnostic. ʻElua ed. Piladelapia, PA: Elsevier; 2018: chap 26.

Zhang J, Zhang W, Leung PS, et al. Ke hoʻomau nei i ka hoʻoulu ʻia ʻana o nā pūnaewele B autoantigen-kikoʻī i ka cirrhosis biliary mua. Hepatology. 2014; 60 (5): 1708-1716. PMID: 25043065 www.ncbi.nlm.nih.gov/pubmed/25043065.