I ka manawa hea kahi biologics e koho ai iā PsA?

Anter

• I ka wā hea e hoʻohana ʻia ai nā biologics?
• ʻO wai ka mea kūpono i nā biologics?
• ʻO Ps area Area a me ka Index Severity (PASI)
• Dermatology Koina o ke Ola Index (DQLI)
• Peripheral psoriatic arthritis
• ʻO ke kuamoʻo psoriatic axial
• ʻO wai ka mea kūpono ʻole no ka biologics?
• ʻO ka lawe lawe ʻana

Hōʻike Overview

ʻO Psoriatic arthritis (PsA) kahi ʻano o ke ahulau e hoʻopili i kekahi poʻe i loaʻa ka psoriasis. He ʻano mau, ʻano lōlō o ka arthritis e hoʻomohala i nā ami nui.

I ka wā ma mua, ua mālama mua ʻia ʻo PsA me nā lāʻau lapaʻau i hoʻokomo ʻia a me oral. Eia naʻe, ʻaʻole holo pono kēia mau lāʻau. Hiki iā lākou ke kumu i nā hopena ʻoluʻolu ʻole. Ma muli o kēia, hoʻohana ʻia kahi hanauna hou o nā lāʻau i kapa ʻia biologics e mālama i ke kaulike a hiki i ka PSA koʻikoʻi.

He ikaika nā biologics, nā lāʻau i hoʻohālikelike ʻia. Hana lākou ma ka pale ʻana i nā ala uila kikoʻī e hoʻokau i ka hana ma psoriasis.

I ka wā hea e hoʻohana ʻia ai nā biologics?

I ka wā ma mua, ʻaʻole hoʻohana ʻia nā meaolaola inā ʻaʻole pono nā ʻano lāʻau ʻē aʻe. ʻO nā lāʻau anti-inflammatory Nonsteroidal (NSAIDs) a me nā lāʻau antirheumatic (DMARDs) e hoʻololi i nā maʻi i kuhikuhi ʻia paha ma mua.

Akā paipai nā kulekele hou i ka hoʻohana ʻana i nā biologics ma ke ʻano he lālani mua no PsA. Kaukaʻi ʻia i kāu hōʻailona psoriatic arthritis a me ka mōʻaukala olakino, hiki i kāu kauka ke koi aku i kekahi o nā biologics no ke kōkua.

ʻO wai ka mea kūpono i nā biologics?

Paipai ʻia e hoʻohana ʻia nā biologics mea hōʻoki (TNFi) biologics ma ke ʻano he koho mua loa i nā poʻe me ka PsA ʻeleu, ʻo ia hoʻi ʻo PsA ke hana nei i nā hōʻailona.

Paipai nā alakaʻi hou mai ke Kulanui ʻAmelika o Rheumatology a me National Psoriasis Foundation e hoʻāʻo mua i ka TNFis i ka poʻe i hoʻohana ʻole i nā lāʻau ʻē aʻe ma mua.

E hoʻoholo ʻia paha kāu hoʻolālā hoʻolālā e ka nui o kāu PsA. ʻAʻohe ala kūpono no ka ʻike ʻana i ke ʻano o ka hewa o PSA nona iho. E hoʻohālikelike paha kāu kauka i ke koʻikoʻi o kāu PsA e pili ana i ka nui o kāu psoriasis. ʻElua ala kauka e ana ai i ka paʻakikī o ka psoriasis e hoʻopili i nā papa kuhikuhi ma lalo.

ʻO Ps area Area a me ka Index Severity (PASI)

Hoʻoholo ʻia ka helu PASI e ka pākēneka o kou ʻili i hoʻopili ʻia e ka psoriasis. Hoʻokumu ʻia kēia i ka nui o kou kino i loaʻa nā plake. ʻO nā plaques nā pākuʻi o ka ʻili i hoʻāla ʻia, wili ʻia, ʻili, maloʻo, a ʻulaʻula.

E hoʻoholo kāu kauka i kāu helu PASI ma mua a i ka wā o ka mālama. ʻO ka pahuhopu o ka mālama ʻana e ʻike i kahi hōʻemi 50 a 75 pakeneka i kāu helu PASI.

Dermatology Koina o ke Ola Index (DQLI)

Nānā ka loiloi DQLI i ka hopena o ka psoriasis ma ke olakino, ka noʻonoʻo, a me ka nohona kanaka.

ʻO ka helu DQLI o 6 a 10 paha ke ʻano o ka hopena o kāu psoriasis i kou olakino. ʻO ka helu i ʻoi aku ma mua o 10 ke ʻano he hopena koʻikoʻi ka hopena i kou olakino.

Hoʻoholo paha kāu kauka ua kūpono ʻoe no nā biologics inā loaʻa iā ʻoe kahi peripheral a axial psoriatic arthritis.

Peripheral psoriatic arthritis

ʻO ka peripheral psoriatic arthritis ka mea e wela ai nā hono i kou mau lima a me kou mau wāwae. Pākuʻi ʻia kēia mau mea:

• kuʻekuʻe lima
• nā kūpeʻe lima
• lima
• wawae

ʻO ke biologic kikoʻī āu e kuhikuhi ai ma muli o ke koʻikoʻi o kāu mau ʻōuli. Akā ʻo infliximab (Remicade) a i ʻole adalimumab (Humira) ke koho i makemake ʻia inā pono ʻoe e kaohi wikiwiki i ka ʻili psoriasis.

ʻO ke kuamoʻo psoriatic axial

Hoʻokumu ke kuʻi psoriatic axial i ka mumū o nā hono i nā wahi aʻe:

• ʻōiwi
• pūhaka
• poʻohiwi

ʻO wai ka mea kūpono ʻole no ka biologics?

ʻAʻole kūpono nā kānaka āpau no ka mālama ʻana me nā biologics. ʻO kahi laʻana, ʻaʻole pono ʻoe e lawe i nā biologics inā hāpai ʻoe a hānai waiu paha. I ka hapanui o nā hihia, ʻaʻole pono ʻoe e lawe i nā biologics inā loaʻa iā ʻoe:

• kahi maʻi ʻino a ʻeleu paha
• maʻi puʻu
• ʻO ka HIV a he hepatitis paha, inā ʻaʻole mālama maikaʻi ʻia kāu ʻano
• maʻi ʻaʻai i kēlā me kēia manawa i nā makahiki he 10 i hala

Inā ʻaʻole nā ​​biologics ke koho pono nāu, e noʻonoʻo paha kāu kauka i nā lāʻau ʻē aʻe, e like me ka hoʻololi ʻana i nā lāʻau antirheumatic (DMARDs).

ʻO ka lawe lawe ʻana

ʻO ka loaʻa ʻana o ka lāʻau no PsA hiki iā ʻoe ke hōʻoluʻolu mai nā ʻōuli ʻeha. ʻO nā biologics nā lāʻau lapaʻau ikaika e hiki ke kōkua iā PsA. He koho paha lākou na ʻoe inā he kaulike a paʻakikī kou PsA, peripheral psoriatic arthritis, a me axial psoriatic arthritis.

E haʻi pono i kāu kauka e pili ana i kāu mau hōʻailona āpau a pehea e pili ai iā PsA i kou ola. E hana ana kāu kauka e ʻike i ka lāʻau kūpono iā ʻoe.