Tecfidera (dimethyl fumarate)

Anter

• He aha ʻo Tecfidera?
• Inoa inoa Tecfidera
• Nā hopena ʻaoʻao Tecfidera
• Nā hopena ʻaoʻao hou aʻe
• Nā hopena hopena koʻikoʻi
• PML
• Flushing
• Lymphopenia
• Nā hopena ate
• ʻO ka hopena maʻi ʻino
• Rash
• Lilo ka lauoho
• Loaʻa kaupaona / Kaumaha emi
• Ka luhi
• ʻEha ʻōpū
• Pohā
• Ka hopena ma ka sperm a i ʻole ka momona o ke kāne
• ʻEha poʻo
• Kāwili
• Kaumaha
• ʻO Shingles
• Kanesa
• Nusea
• Konipōpō
• Puʻupuʻu
• ʻO Insomnia
• ʻUpala
• ʻEha hui
• Waha maloo
• Nā hopena ma nā maka
• Nā hōʻailona like Flu
• Nā hopena ʻaoʻao lōʻihi
• Hoʻohana ʻo Tecfidera
• ʻO Tecfidera no MS
• ʻO Tecfidera no ka psoriasis
• Nā koho ʻē aʻe iā Tecfidera
• ʻO Tecfidera vs. nā lāʻau ʻē aʻe
• Tecfidera vs. Aubagio
• ʻO Tecfidera vs. Copaxone
• ʻO Tecfidera vs. Ocrevus
• ʻO Tecfidera vs. Tysabri
• ʻO Tecfidera vs. Gilenya
• Tecfidera vs. interferon (Avonex, Rebif)
• ʻO Tecfidera vs. Protandim
• Tecfidera lāʻau kō
• Nā hana no nā sclerosis he nui
• He aha inā e haʻo wau i kahi lāʻau?
• Pono wau e hoʻohana i kēia lāʻau lōʻihi?
• Pehea e lawe ai iā Tecfidera
• Manawa
• Lawe iā Tecfidera me ka meaʻai
• Hiki iā Tecfidera ke haki?
• Hāpai a me Tecfidera
• ʻO Breastfeeding a me Tecfidera
• Pehea e hana ai ʻo Tecfidera
• Pehea ka lōʻihi o ka hana?
• ʻO Tecfidera a me ka waiʻona
• Nā launa pū ʻo Tecfidera
• ʻO Tecfidera a me ocrelizumab (Ocrevus)
• ʻO Tecfidera a me ibuprofen
• ʻO Tecfidera a me ka aspirin
• Nā nīnau e pili ana iā Tecfidera
• No ke aha e kumu ai ʻo Tecfidera i ka flush?
• Pehea e hiki ai iā ʻoe ke pale i ka hoʻoheheʻe ʻana mai Tecfidera?
• Luhi paha ʻo Tecfidera iā ʻoe?
• He immunosuppressant ʻo Tecfidera?
• Pono wau e hopohopo no ka puka ʻana o ka lā i ka lawe ʻana iā Tecfidera?
• Pehea ka maikaʻi o Tecfidera?
• No ke aha he mau ʻaoʻao dosing ʻokoʻa kaʻu ma hope o ka pule mua?
• Pono wau e kiʻi i nā hoʻokolohua koko ʻoiai au ma Tecfidera?
• ʻO Tecfidera overdose
• Nā hōʻailona overdose
• He aha e hana ai inā he overdose
• Nā ʻōlelo aʻoaʻo no Tecfidera
• Pau ʻole ʻo Tecfidera
• ʻO ka ʻike ʻoihana no Tecfidera
• Mekanism o ka hana
• Pharmacokinetics a me ka metabolism
• Nā Kūʻai Kūʻai
• Waihona
• Ke kuhikuhi nei i ka ʻike

He aha ʻo Tecfidera?

ʻO Tecfidera (dimethyl fumarate) kahi lāʻau lapaʻau inoa inoa inoa inoa inoa. Hoʻohana ʻia ia e mālama i nā ʻano relapsing o nā sclerosis maha (MS).

Hoʻokaʻawale ʻia ʻo Tecfidera ma ke ʻano he hoʻololi hoʻoponopono maʻi no MS. Hoʻoemi ia ka makaʻu o ka hoʻi hou ʻana o MS a i ka 49 pākēneka i loko o ʻelua mau makahiki. Hoʻoemi ia i ka makaʻu o ka hōʻemi kino kīnā ʻana ma kahi o 38 pakeneka.

Hele mai ʻo Tecfidera ma ke ʻano he capsule waha waha i hoʻopaneʻe ʻia. Loaʻa ia i nā ikaika ʻelua: 120-mg capsule a me 240-mg capsule.

Inoa inoa Tecfidera

ʻO Tecfidera kahi lāʻau lapaʻau inoa inoa. ʻAʻole i loaʻa i kēia manawa ma ke ʻano he lāʻau laula.

Loaʻa iā Tecfidera ka lāʻau dimethyl fumarate.

Nā hopena ʻaoʻao Tecfidera

Hiki iā Tecfidera ke hana i nā hopena ʻoluʻolu a koʻikoʻi paha. Loaʻa i ka papa inoa aʻe kekahi o nā hopena ʻaoʻao nui i hiki ke hana ʻia i ka lawe ʻana iā Tecfidera. ʻAʻole pili kēia papa inoa i nā hopena ʻaoʻao āpau.

No ka ʻike hou aku e pili ana i nā hopena ʻē aʻe o Tecfidera, a i ʻole nā ​​ʻōlelo aʻoaʻo e pili ana i ka hopena o ka hopena pilikia, e kamaʻilio me kāu kauka a kauka paha.

Nā hopena ʻaoʻao hou aʻe

ʻO nā hopena ʻē aʻe i ʻike pinepine ʻia o Tecfidera:

• flushing (ʻulaʻula o ka maka a me ka ʻāʻī)
• huhū ka ʻōpū
• ʻeha ka ʻōpū
• pāhoehoe
• nausea
• ka luaʻi
• ʻili ʻili
• hūwī

E hōʻemi a hele paha kēia mau hopena i loko o kekahi mau pule. Inā ʻoi aku ke koʻikoʻi a i ʻole hele aku, e kamaʻilio me kāu kauka a kauka paha.

Nā hopena hopena koʻikoʻi

Kāhea koke i kāu kauka inā loaʻa nā hopena koʻikoʻi. Kāhea iā 911 inā manaʻo kou mau hōʻailona i ka hoʻoweliweli ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino. Hiki i nā hopena ʻē aʻe ke hoʻopili i kēia mau mea:

• pāheʻe ʻino
• leukoencephalopathy multifocal holomua (PML)
• hoʻemi i ke kiʻekiʻe o ke kōpō keokeo (lymphopenia)
• hōʻino ka ate
• hopena hopena maʻi ʻino

E ʻike ma lalo no ka ʻike e pili ana i kēlā me kēia hopena ʻaoʻao koʻikoʻi.

PML

ʻO ka leukoencephalopathy multifocal holomua (PML) kahi maʻi hoʻoweliweli o ka lolo i hoʻokumu ʻia e ka maʻi virus JC. Hana wale ia i ka poʻe nona ka ʻōnaehana pale ʻole e holo pono ana. He mea liʻiliʻi loa, ua kū ʻo PML i ka poʻe me MS e lawe nei iā Tecfidera. I kēia mau hihia, ua hoʻemi ka poʻe i hoʻomohala i ka PML i nā pae o ke koko keʻokeʻo.

I mea e pale aku ai i ka PML, e hana pinepine kāu kauka i nā hoʻokolohua koko i kou wā e mālama ai e nānā i nā pae o ke koko keʻokeʻo. Inā haʻahaʻa loa kāu mau pae, hiki i kāu kauka ke koi aku iā ʻoe e haʻalele iā Tecfidera.

E nānā pū kāu kauka iā ʻoe no nā ʻōuli o PML ke lawe ʻoe i ka lāʻau. Pākuʻi ʻia paha nā ʻōuli:

• nāwaliwali ma kekahi ʻaoʻao o kou kino
• pilikia pilikia ʻike
• clumsiness
• pilikia pilikia hoʻomanaʻo
• huikau

Inā loaʻa kēia mau ʻōuli iā ʻoe ke lawe nei iā Tecfidera, e kāhea koke aku i kāu kauka. E hana paha kāu kauka i nā hoʻokolohua e nānā ai inā he PML kāu, a e hōʻoki paha lākou i kāu lāʻau me Tecfidera.

Flushing

ʻO Flushing (ʻulaʻula o kou alo a i ʻole ʻāʻī) kahi hopena ʻaoʻao maʻamau o Tecfidera. Hana ʻia a hiki i ka 40 pākēneka o ka poʻe i hoʻohana i ka lāʻau. Kū pinepine nā hopena Flush ma hope koke o kou hoʻomaka ʻana e lawe iā Tecfidera, a laila hoʻomaikaʻi a hele hele loa paha i kahi mau pule.

I ka hapanui o nā hihia, palupalu ka flushing a kaulike i ke koʻikoʻi a me nā ʻōuli e like me:

• manaʻo o ka mehana i loko o ka ʻili
• ʻulaʻula ʻili
• ʻūlili
• manaʻo wela

No kekahi, hiki i nā ʻōuli o ka flush ke lilo i koʻikoʻi a hiki ʻole ke hoʻomanawanui. Ma kahi o 3 pākēneka o ka poʻe e lawe iā Tecfidera e hoʻopau i ka hoʻōki ʻana i ka lāʻau ma muli o ke kahe nui.

ʻO ka lawe ʻana iā Tecfidera me ka meaʻai hiki ke kōkua i ka hoʻoliʻiliʻi. Lawe i kahi aspirin 30 mau minuke ma mua o ka lawe ʻana iā Tecfidera hiki ke kōkua pū kekahi.

Lymphopenia

Hiki iā Tecfidera ke kumu i ka lymphopenia, kahi pae hoʻemi o ke koko keʻokeʻo i kapa ʻia he lymphocytes. Hiki i ka Lymphopenia ke hoʻonui i kāu makaʻu i nā maʻi. Hiki i nā ʻōuli o ka lymphopenia ke hoʻopili pū me:

• fiva
• hoʻonui ʻia nā lymph node
• ami ami

E hana ana kāu kauka i nā hoʻokolohua koko ma mua a ma kāu mālama ʻana me Tecfidera. Inā e haʻahaʻa loa kāu mau lymphocyte, e ʻōlelo paha kāu kauka e hōʻoki ʻoe i ka lawe ʻana iā Tecfidera no kahi manawa i hoʻonohonoho ʻia, a i ʻole mau.

Nā hopena ate

Hiki iā Tecfidera ke kumu i nā hopena ʻaoʻao o ke ake. Hiki paha ke hoʻonui i nā pae o kekahi mau ʻenema ate i ana ʻia e nā hoʻokolohua koko. Hana pinepine kēia hoʻonui i nā malama ʻeono mua o ka mālama ʻana.

No ka hapanui o ka poʻe, ʻaʻole hoʻokumu kēia mau hoʻonui i nā pilikia. Akā no kekahi poʻe liʻiliʻi, lilo lākou i mea koʻikoʻi a hōʻike i ka hōʻino o ke ake. Hiki i nā ʻōuli o ka hōʻino o ke ake ke komo pū:

• luhi
• nalo ʻai ʻole
• melemele o kou ʻili a i ʻole nā ​​keʻokeʻo o kou mau maka

Ma mua a ma kahi o kāu mālama ʻana me Tecfidera, e hana ana kāu kauka i nā hoʻokolohua koko e nānā i kāu hana ate. Inā hoʻonui ka nui o nā enzymes o kou ake, hiki i kāu kauka ke hooki iā ʻoe i ka lawe ʻana i kēia lāʻau.

ʻO ka hopena maʻi ʻino

Hiki ke hana i nā hopena maʻi kūpilikiʻi, me ka anaphylaxis, i kekahi poʻe e lawe iā Tecfidera. Hiki i kēia ke hana i kēlā me kēia manawa i ka wā o ka lapaʻau. Hiki i nā ʻōuli o ke ʻano hōʻalo ke komo pū me:

• pilikia hanu
• ʻeha ka ʻili a hives paha
• pehu o kou lehelehe, alelo, puʻu

Inā loaʻa ʻoe i kahi hopena maʻi ʻaʻa, e kāhea koke aku i kāu kauka a i ʻole kikowaena kikowaena lāʻau ʻona kūloko. Inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele i kahi lumi pilikia kokoke loa.

Inā loaʻa iā ʻoe kahi hopena maʻi ʻino i kēia lāʻau i ka wā i hala, ʻaʻole hiki iā ʻoe ke lawe hou. ʻO ka hoʻohana ʻana i ka lāʻau i hiki ke make. Inā ua hana ʻoe i kahi hopena i kēia lāʻau ma mua, e kamaʻilio me kāu kauka ma mua o ka lawe hou ʻana.

Rash

Ma kahi o 8 pākēneka o ka poʻe i lawe iā Tecfidera i loaʻa i ka ʻili māmā ma hope o ka lawe ʻana iā Tecfidera no kekahi mau lā. Hele paha ka ʻōpala me ka hoʻohana mau. Inā ʻaʻole e hele a lilo i mea hoʻonāukiuki, e kamaʻilio me kāu kauka.

Inā kū koke kahi wīwī ma hope o kou lawe ʻana i ka lāʻau, hiki i kahi hopena maʻi. Inā pilikia ʻoe i ka hanu ʻana a i ʻole ka pehu ʻana o kou mau lehelehe a i ʻole alelo, hiki i kēia ke ʻano he hopena anaphylactic koʻikoʻi. Inā manaʻo ʻoe ke loaʻa nei ʻoe i ka hopena maʻi maʻi i kēia lāʻau, e kāhea iā 911.

Lilo ka lauoho

ʻAʻole ka hopena o ka lauoho i ka hopena i kū i ka noiʻi ʻana iā Tecfidera. Eia nō naʻe, ua hala ka lauoho o kekahi poʻe e lawe iā Tecfidera.

I hoʻokahi hōʻike, ua hoʻomaka ka wahine i hoʻomaka e lawe iā Tecfidera e lilo ka lauoho ma hope o ka lawe ʻana i ka lāʻau no ʻelua a ʻekolu paha mahina. Ua lohi kona lauoho lauoho ma hope o kona hoʻomau ʻana i ka lāʻau i ʻelua mau mahina, a ua hoʻomaka ka ulu ʻana o kona lauoho.

Loaʻa kaupaona / Kaumaha emi

ʻO ka loaʻa ʻana o ke kaupaona a me ke kaupaona ʻana ʻaʻole ia kahi hopena i kū i ka noiʻi ʻana iā Tecfidera. Eia nō naʻe, ua loaʻa ka waiwai i kekahi poʻe i lawe i ka lāʻau. ʻO kekahi poʻe i loaʻa ka pohō kaumaha i ka lawe ʻana iā Tecfidera. ʻAʻole maopopo inā ʻo Tecfidera ke kumu o ka loaʻa ʻana o ke kaumaha a lilo paha.

Ka luhi

Hiki i ka poʻe i lawe iā Tecfidera ke luhi. I hoʻokahi aʻo, ua luhi ka luhi ma 17 pākēneka o ka poʻe i lawe. E hoʻemi a hele paha kēia hopena ʻaoʻao me ka hoʻohana mau ʻana o ka lāʻau.

ʻEha ʻōpū

Ma kahi o 18 pākēneka o ka poʻe e lawe iā Tecfidera i loaʻa i ka ʻeha o ka ʻōpū. ʻO ka hopena maʻamau ka hopena ma ka mahina mua o ka mālama ʻana a hoʻoliʻiliʻi a hele paha me ka hoʻomau o ka hoʻohana ʻana i ka lāʻau.

Pohā

Ma kahi o 14 pākēneka o ka poʻe e lawe i ka Tecfidera i ka maʻi pākī. ʻO kēia hopena ʻaoʻao ka mea maʻamau i ka malama mua o ka mālama ʻana a hoʻoliʻiliʻi pinepine a hele paha me ka hoʻohana mau.

Ka hopena ma ka sperm a i ʻole ka momona o ke kāne

ʻAʻole i loiloi nā loiloi kanaka i ka hopena o Tecfidera i ka sperm a i ʻole ka momona kāne. I nā noiʻi holoholona, ​​ʻaʻole pili ʻo Tecfidera i ka momona, akā ʻaʻole mau ka ʻike i nā holoholona i ka mea e hiki mai i nā kānaka.

ʻEha poʻo

ʻO kekahi poʻe e lawe iā Tecfidera i ka maʻi poʻo. Eia naʻe, maopopo ʻole inā ʻo Tecfidera ke kumu. I hoʻokahi noiʻi, 16 pākēneka o ka poʻe i lawe iā Tecfidera i loaʻa i nā poʻo o ke poʻo, akā ʻo ka maʻi poʻo pinepine pinepine i nā poʻe i lawe i kahi pill placebo.

Kāwili

Ma kahi o 8 pākēneka o ka poʻe e lawe iā Tecfidera i ka ʻili ʻili. E hala paha kēia hopena me ka hoʻohana mau ʻana o ka lāʻau. Inā ʻaʻole e hele a i ʻole inā lilo ia i mea hoʻopilikia, e kamaʻilio me kāu kauka.

Kaumaha

ʻO kekahi poʻe e lawe iā Tecfidera he naʻau kaumaha. Eia naʻe, maopopo ʻole inā ʻo Tecfidera ke kumu. I hoʻokahi noi, he 8 pākēneka o ka poʻe i lawe iā Tecfidera i loaʻa i ke ʻano kaumaha o ke kaumaha, akā ua hana pinepine ʻia kēia i ka poʻe i lawe i ka pill placebo.

Inā loaʻa iā ʻoe nā ʻōuli o ke kaumaha e lilo i mea hoʻonāukiuki, e kamaʻilio me kāu kauka e pili ana i nā ala e hoʻomaikaʻi ai i kou ʻano.

ʻO Shingles

I nā noiʻi maʻi, ʻaʻole i hoʻonui ʻo Tecfidera i ka makaʻu o ka shingles. Eia nō naʻe, aia kahi hōʻike o shingles i kahi wahine me ka sclerosis he nui nāna i lawe iā Tecfidera.

Kanesa

I nā noiʻi maʻi, ʻaʻole i hoʻonui ʻo Tecfidera i ka makaʻu o ka maʻi ʻaʻai.ʻO ka ʻoiaʻiʻo, ke ʻimi nei kekahi poʻe noiʻi inā paha e kōkua ʻo Tecfidera i ka pale ʻana a i ʻole ka mālama ʻana i kekahi mau maʻi maʻi maʻi.

Nusea

Ma kahi o 12 pākēneka o ka poʻe i lawe iā Tecfidera i loaʻa i ka nausea. E hala paha kēia hopena me ka hoʻohana mau ʻana o ka lāʻau. Inā ʻaʻole e hele a i ʻole inā lilo ia i mea hoʻopilikia, e kamaʻilio me kāu kauka.

Konipōpō

ʻAʻole i hōʻike ʻia ʻo Constipation i nā noiʻi maʻi o Tecfidera. Eia nō naʻe, ʻo ka poʻe e lawe iā Tecfidera i kekahi manawa loaʻa ka paʻa paʻa. ʻAʻole maopopo inā he hopena ʻaoʻao kēia o Tecfidera.

Puʻupuʻu

ʻAʻole i hōʻike ʻia ʻo Bloating i nā noiʻi maʻi o Tecfidera. Eia nō naʻe, ʻo ka poʻe e lawe iā Tecfidera i kekahi manawa e kolo. ʻAʻole maopopo inā he hopena ʻaoʻao kēia o Tecfidera.

ʻO Insomnia

ʻAʻole i hōʻike ʻia ʻo Insomnia (pilikia e hiamoe ana a hiamoe paha) i nā noiʻi olakino o Tecfidera. Eia naʻe, ʻo ka poʻe e lawe iā Tecfidera i kekahi manawa loaʻa ka hiamoe. ʻAʻole maopopo inā he hopena ʻaoʻao kēia o ka lāʻau.

ʻUpala

I nā noiʻi maʻi, ʻaʻole i hoʻonui ʻo Tecfidera i ka makaʻu o ka palapū. Eia nō naʻe, he nui ka poʻe i loaʻa iā MS e ʻōlelo nei he pākī pinepine ko lākou. ʻAʻole maopopo ke kumu o kēia. Ua helu ʻia ma lalo kahi mau manaʻo.

• Ke holo nei ʻo MS, mālama i ke kaulike a me ka hoʻohui ʻana e lilo i mea paʻakikī. Hiki i kēia ke hopena i ke kuʻi ʻana i nā mea a hāʻule paha, nā mea ʻelua e hiki ke hōʻeha.
• ʻO kahi kanaka me MS nāna e lawe iā Tecfidera paha e lawe i ka aspirin e kōkua ai i ka pale ʻana i ka wai. Hiki i ka Aspirin ke hoʻonui i ka palapū.
• ʻO ka poʻe i lawe i nā steroid i loaʻa ka ʻili lahilahi, a hiki ke maʻalahi iā lākou e paopao. No laila, ʻo ka poʻe me MS i loaʻa ka mōʻaukala o ka hoʻohana steroid hiki ke ʻike i ka nui o ka palapū.

Inā ʻoe hopohopo e pili ana i ka palapū ʻoiai e lawe ana iā Tecfidera, e kamaʻilio me kāu kauka. Hana paha kāu kauka i nā hoʻokolohua koko e nānā ai no nā kumu ʻē aʻe.

ʻEha hui

Hiki i ka ʻeha hui ke kū i ka poʻe i lawe iā Tecfidera. I hoʻokahi noiʻi, 12 pākēneka o ka poʻe i lawe iā Tecfidera i loaʻa i ka ʻeha pū. Ua hōʻike ʻia kahi hōʻike ʻekolu i loaʻa i ka ʻeha kaulike a paʻakikī paha ma hope o ka hoʻomaka ʻana iā Tecfidera.

E hoʻemi a hele paha kēia hopena ʻaoʻao me ka hoʻohana mau ʻana o ka lāʻau. Hiki ke hoʻomaikaʻi pū ka ʻeha hui ke kū ʻia ʻo Tecfidera.

Waha maloo

ʻAʻole i hōʻike ʻia ka waha maloʻo ma nā noiʻi maʻi o Tecfidera. Eia nō naʻe, he waha maloʻo ko ka poʻe e lawe iā Tecfidera i kekahi manawa. ʻAʻole maopopo inā he hopena ʻaoʻao kēia o Tecfidera.

Nā hopena ma nā maka

ʻAʻole i hōʻike ʻia nā hopena pili e pili ana i ka maka i nā noiʻi maʻi o Tecfidera. Eia naʻe, ua ʻōlelo kekahi poʻe e lawe i ka lāʻau i loaʻa iā lākou nā hōʻailona e like me:

• maka maloʻo
• mimilo ka maka
• ʻike hihi

ʻAʻole maopopo inā pili kēia mau hopena o ka maka e ka lāʻau a i ʻole kekahi mea ʻē aʻe. Inā loaʻa iā ʻoe kēia mau hopena a ʻaʻole lākou e hele a lilo lākou i mea hoʻonāukiuki, e kamaʻilio me kāu kauka.

Nā hōʻailona like Flu

Ua loaʻa ka maʻi palū a me nā maʻi flu-like i loko o nā noiʻi o ka poʻe e lawe ana iā Tecfidera. I hoʻokahi o ia ʻano noiʻi, 6 pākēneka o ka poʻe i hoʻohana i ka lāʻau i loaʻa i kēia mau hopena, akā pinepine ka hopena i nā poʻe i lawe i kahi pill placebo.

Nā hopena ʻaoʻao lōʻihi

ʻO nā loiloi e loiloi ana i nā hopena o Tecfidera i hala ʻelua a ʻeono mau makahiki. I hoʻokahi hoʻopaʻa ʻana i ʻeono mau makahiki, ʻo nā hopena ʻāpana maʻamau ka:

• Holo hou ʻo MS
• ʻeha ka ʻāʻī a i ʻole ka ihu ihu
• ʻōpala
• maʻi hanu
• maʻi maʻi urinary tract
• ʻeha poʻo
• pāhoehoe
• luhi
• ʻeha ka ʻōpū
• ʻeha ma ke kua, nā lima, a me nā wāwae

Inā lawe ʻoe iā Tecfidera a loaʻa nā hopena ʻaoʻao i hele ʻole a lilo i koʻikoʻi a hoʻopilikia paha, e kamaʻilio me kāu kauka. Hōʻike paha lākou i nā ala e hōʻemi a hoʻopau ai i nā hopena ʻaoʻao, a i ʻole ʻōlelo paha lākou e hoʻōki i ka lawe ʻana i ka lāʻau.

Hoʻohana ʻo Tecfidera

Ua ʻae ʻia ʻo Tecfidera e ka Food and Drug Administration (FDA) no ka mālama ʻana i nā sclerosis (MS) he nui.

ʻO Tecfidera no MS

Ua ʻae ʻia ʻo Tecfidera no ka mālama ʻana i nā ʻano relapsing o MS, nā ʻano maʻamau o MS. I kēia mau ʻano, hōʻeha ka ʻino a i ʻole nā ​​ʻōuli hou i kahi hanana (hoʻi hou), a ukali ʻia e nā wā o ka hoʻihoʻi hapa a hoʻopau piha paha (remission).

Hoʻoemi ʻo Tecfidera i ka makaʻu o ka hoʻi hou ʻana o MS a i ka 49 pākēneka i loko o ʻelua mau makahiki. Hoʻoemi ia i ka makaʻu o ka hōʻemi kino kīnā ʻana ma kahi o 38 pakeneka.

ʻO Tecfidera no ka psoriasis

Hoʻohana ʻia ʻo Tecfidera i kahi lepili e mālama ai i ka plake psoriasis. ʻO ka hoʻohana ʻana i kahi lepili ke ʻae ʻia kahi lāʻau e mālama i hoʻokahi kūlana akā hoʻohana ʻia e mālama i kahi ʻano ʻokoʻa.

I loko o kahi noiʻi hoʻokolohua, ma kahi o 33 pākēneka o ka poʻe e lawe nei iā Tecfidera i maopopo a maʻalahi paha ma hope o 16 mau pule o ka mālama ʻana. Ma kahi o 38 pākēneka o ka poʻe e lawe ana i ka lāʻau i loaʻa kahi 75 pakeneka i hoʻomaikaʻi ʻia i ka papa kuhikuhi o ka nui o ka plaque a me nā wahi i hoʻopilikia ʻia.

Nā koho ʻē aʻe iā Tecfidera

Loaʻa nā lāʻau lapaʻau e mālama ai i nā ʻano relapsing o nā sclerosis (MS) he nui. ʻO nā laʻana o kēia mau lāʻau:

• interferon beta-1a (Avonex, Rebif)
• interferon beta-1b (Betaseron)
• glatiramer acetate (Copaxone, Glatopa)
• IV immunoglobulin (Bivigam, Gammagard, a me nā mea ʻē aʻe)
• monoclonal antibodies e like me:
• alemtuzumab (Lemtrada)
• natalizumab (Tysabri)
• rituximab (Rituxan)
• ocrelizumab (Ocrevus)
• fingolimod (Gilenya)
• teriflunomide (Aubagio)

Kaha: kekahi o nā lāʻau i helu ʻia ma aneʻi e hoʻohana ʻia i ka lepili waho e mālama ai i nā ʻano relapsing o MS.

ʻO Tecfidera vs. nā lāʻau ʻē aʻe

Mahalo paha ʻoe pehea e hoʻohālikelike ai ʻo Tecfidera i nā lāʻau ʻē aʻe i kuhikuhi ʻia no nā hoʻohana like. Ma lalo nā hoʻohālikelike ma waena o Tecfidera a me kekahi mau lāʻau.

Tecfidera vs. Aubagio

Hoʻohui ʻia ʻo Tecfidera lāua ʻo Aubagio (teriflunomide) ma ke ʻano he hoʻoponopono hoʻoponopono hoʻololi maʻi. Hoʻoemi lāua i kekahi i nā hana pale o ke kino, akā hana lākou i nā ʻano like ʻole.

Hoʻohana

ʻO Tecfidera lāua ʻo Aubagio i ʻae ʻia e FDA no ka mālama ʻana i nā ʻano relapsing o nā sclerosis (MS) he nui.

Nā ʻano lāʻau

Hele mai ʻo Tecfidera ma ke ʻano he lohi-hoʻokuʻu i ka capsule waha i lawe ʻia i ʻelua mau lā i kēlā me kēia lā. Hele mai ʻo Aubagio ma ke ʻano he papaha waha i lawe ʻia i hoʻokahi manawa i kēlā me kēia lā.

Nā hopena a me nā pilikia

Loaʻa iā Tecfidera lāua ʻo Aubagio kekahi mau ʻaoʻao a ʻokoʻa kekahi. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

* Ua hoʻolaha ʻo Aubagio i nā ʻōlelo aʻoaʻo mai ka FDA. ʻO kēia nā ʻōlelo aʻoaʻo ikaika a ka FDA e koi ai. ʻO ka leka hoʻomaopopo e hōʻike i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

Ka hoʻokō ʻana

Kūpono ʻo Tecfidera lāua ʻo Aubagio no ka mālama ʻana iā MS. ʻAʻole i hoʻohālikelike pololei ʻia ka maikaʻi o kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, i hoʻokahi anamanaʻo, ua hoʻohālikelike ʻia lākou a ʻike ʻia he mau pono like.

Nā kumukūʻai

Loaʻa ʻo Tecfidera lāua ʻo Aubagio ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole loaʻa nā mana generic o kēia mau lāʻau. ʻOi aku ka liʻiliʻi o nā kumu Generic ma mua o nā lāʻau lapaʻau inoa.

ʻOi aku ke kumukūʻai ʻo Tecfidera ma mua o Aubagio. Eia nō naʻe, pili ke kumukūʻai pololei āu e uku ai i kāu hoʻolālā ʻinikua.

ʻO Tecfidera vs. Copaxone

Hoʻohui ʻia ʻo Tecfidera a me Copaxone (glatiramer acetate) ma ke ʻano he hoʻoponopono hoʻoponopono hoʻololi maʻi. Hoʻoemi lāua i kekahi i nā hana pale o ke kino, akā hana lākou i nā ʻano like ʻole.

Hoʻohana

Ua ʻae ʻia ʻo Tecfidera a me Copaxone i ʻāpono ʻia no ka mālama ʻana i nā ʻano relapsing o nā sclerosis (MS) ʻelua.

Nā ʻano lāʻau

ʻO kahi keu pono o Tecfidera ka mea i lawe ʻia e ka waha. Hele mai ia ma ke ʻano he lohi-hoʻokuʻu i ka capsule waha i lawe ʻia i ʻelua mau lā i kēlā me kēia lā.

Pono e hoʻopili ʻia ʻo Copaxone. Hele mai ia ma ke ʻano he injection indcutaneite ponoʻī. Hiki ke hāʻawi ʻia ma ka home i hoʻokahi manawa i kēlā me kēia lā a i ʻole ʻekolu mau manawa i kēlā me kēia pule.

Nā hopena a me nā pilikia

Loaʻa iā Tecfidera lāua ʻo Copaxone kekahi mau hopena ʻē aʻe a ʻokoʻa kekahi. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Ka hoʻokō ʻana

He maikaʻi nā Tecfidera a me Copaxone no ka mālama ʻana iā MS. ʻAʻole i hoʻohālikelike pololei ʻia ka maikaʻi o kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, e like me kahi kālailai, ʻoi aku ka maikaʻi o Tecfidera ma mua o Copaxone no ka pale ʻana i ka hoʻi hou ʻana a me ka lohi o ka hōʻino ʻana o ke kīnā.

Nā kumukūʻai

Loaʻa ʻo Tecfidera ma ke ʻano he lāʻau lapaʻau inoa. Loaʻa ʻo Copaxone ma ke ʻano he lāʻau lapaʻau inoa. Loaʻa pū ia i kahi ʻano laulā i kapa ʻia glatiramer acetate.

ʻOi aku ka liʻiliʻi o ke kumu kūʻai generic o Copaxone ma mua o Tecfidera. ʻO Copaxone a me Tecfidera ka inoa ʻo Brand-maʻamau ke kumu kūʻai like. ʻO ka nui maoli āu e uku ai e pili ana i kāu hoʻolālā ʻinikua.

ʻO Tecfidera vs. Ocrevus

Hoʻokaʻawale ʻia ʻo Tecfidera lāua ʻo Ocrevus (ocrelizumab) ma ke ʻano he hoʻoponopono hoʻoponopono hoʻololi maʻi. Hoʻoiho lāua i kekahi mau hana pale o ke kino, akā hana lākou i nā ʻano like ʻole.

Hoʻohana

Ua ʻae ʻia ʻo Tecfidera lāua ʻo Ocrevus no ka mālama ʻana i nā ʻano relapsing o nā sclerosis (MS) ʻelua. Ua ʻae ʻia ʻo Ocrevus no ka mālama ʻana i nā ʻano holomua o MS.

Nā ʻano lāʻau

ʻO kahi keu pono o Tecfidera hiki ke lawe ʻia e ka waha. Ua hele mai me he hoʻopaneʻe-hoʻokuʻu i ka capsule waha i lawe ʻia i ʻelua mau lā i kēlā me kēia lā.

Pono e injected iā Ocrevus me ka hoʻohana ʻana i kahi infravenous (IV) infusion. Pono e lawelawe ʻia i kahi haukapila a haukapila paha. Ma hope o nā mahele ʻelua, hāʻawi ʻia ʻo Ocrevus i kēlā me kēia ʻeono mau mahina.

Nā hopena a me nā pilikia

Loaʻa iā Tecfidera lāua ʻo Ocrevus kekahi mau hopena ʻaoʻao a ʻokoʻa kekahi. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Ka hoʻokō ʻana

Kūpono ʻo Tecfidera lāua ʻo Ocrevus no ka mālama ʻana iā MS, akā ʻaʻole maopopo inā maikaʻi ka hana a kekahi ma mua o kekahi. ʻAʻole i hoʻohālikelike pololei ʻia ka maikaʻi o kēia mau lāʻau i nā noiʻi maʻi.

Nā kumukūʻai

Loaʻa ʻo Tecfidera lāua ʻo Ocrevus i mau lāʻau lapaʻau inoa inoa. ʻAʻole lākou i loaʻa i nā mana laulā, kahi hiki ke ʻoi aku ka liʻiliʻi ma mua o nā lāʻau lapaʻau inoa.

ʻOi aku paha ke kumukūʻai o Ocrevus ma mua o Tecfidera. ʻO ka nui maoli āu e uku ai e pili ana i kāu hoʻolālā ʻinikua.

ʻO Tecfidera vs. Tysabri

Hoʻokaʻawale ʻia ʻo Tecfidera lāua ʻo Tysabri (natalizumab) ma ke ʻano he hoʻoponopono hoʻoponopono hoʻololi maʻi. Hoʻoemi nā lāʻau ʻelua i kekahi mau hana pale o ke kino, akā hana lākou i nā ʻano like ʻole.

Hoʻohana

Ua ʻae ʻia ʻo Tecfidera lāua ʻo Tysabri no ka mālama ʻana i nā ʻano relapsing o nā sclerosis (MS) ʻelua. Ua ʻae ʻia ʻo Tysabri no ka mālama ʻana i ka maʻi o Crohn.

Nā ʻano lāʻau

ʻO kahi keu pono o Tecfidera ka mea i lawe ʻia e ka waha. Hele mai ʻo Tecfidera ma ke ʻano he lohi-hoʻokuʻu i ka capsule waha i lawe ʻia i ʻelua mau lā i kēlā me kēia lā.

Pono e lawelawe ʻia ʻo Tysabri ma ke ʻano he infravenous (IV) infusion i hāʻawi ʻia i loko o kahi haukapila a haukapila paha. Hāʻawi ʻia hoʻokahi manawa i kēlā me kēia mahina.

Nā hopena a me nā pilikia

Loaʻa iā Tecfidera lāua ʻo Tysabri kekahi ʻano ʻaoʻao a ʻokoʻa kekahi. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

* Ua hoʻopili ʻia kēia mau lāʻau ʻelua me ka leukoencephalopathy multifocal holomua (PML), akā ʻo Tysabri wale nō kahi ʻōlelo aʻoaʻo e pili ana i ka pahu mai ka FDA mai. ʻO kēia ka ʻōlelo aʻo ikaika loa a ka FDA e koi ai. ʻO ka leka hoʻomaopopo e hōʻike i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

Ka hoʻokō ʻana

Kūpono ʻo Tecfidera lāua ʻo Tysabri no ka mālama ʻana iā MS. ʻAʻole i hoʻohālikelike pololei ʻia ka maikaʻi o kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, e like me kahi kālailai, ʻoi aku paha ka maikaʻi o kā Tysabri ma mua o Tecfidera no ka pale ʻana i ka hoʻi hou.

He mea nui e hoʻomaopopo ma muli o ka makaʻu o ka PML, ʻaʻole maʻamau ʻo Tysabri i kahi lāʻau lapaʻau mua loa na MS.

Nā kumukūʻai

Loaʻa ʻo Tecfidera lāua ʻo Tysabri ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole loaʻa nā mana generic o kēia mau lāʻau. ʻOi aku ka uku o nā Generics ma mua o nā inoa inoa inoa inoa.

ʻOi aku ke kumukūʻai ʻo Tecfidera ma mua o Tysabri. ʻO ka nui maoli āu e uku ai e pili ana i kāu hoʻolālā ʻinikua.

ʻO Tecfidera vs. Gilenya

Hoʻokaʻawale ʻia ʻo Tecfidera lāua ʻo Gilenya (fingolimod) ma ke ʻano he hoʻoponopono hoʻoponopono hoʻololi maʻi. Hoʻoiho lāua i kekahi mau hana pale o ke kino, akā hana lākou i nā ʻano like ʻole.

Hoʻohana

Ua ʻae ʻia ʻo Tecfidera lāua ʻo Gilenya no ka mālama ʻana i nā ʻano relapsing o nā sclerosis (MS) ʻelua.

Nā ʻano lāʻau

Hele mai ʻo Tecfidera ma ke ʻano he lohi-hoʻokuʻu i ka capsule waha i lawe ʻia i ʻelua mau lā i kēlā me kēia lā. Hele mai ʻo Gilenya ma ke ʻano he capsule waha i lawe ʻia i hoʻokahi manawa i kēlā me kēia lā.

Nā hopena a me nā pilikia

Loaʻa iā Tecfidera lāua ʻo Gilenya kekahi ʻano ʻaoʻao a ʻokoʻa kekahi. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Ka hoʻokō ʻana

He maikaʻi nā Tecfidera lāua ʻo Gilenya no ka mālama ʻana iā MS. ʻAʻole i hoʻohālikelike pololei ʻia ka maikaʻi o kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, e like me ka loiloi hoʻokahi, hana like ʻo Tecfidera lāua ʻo Gilenya e pili pono ana i ka pale ʻana i ka hoʻi hou.

Nā kumukūʻai

Loaʻa ʻo Tecfidera lāua ʻo Gilenya ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole loaʻa nā mana generic o kēia mau lāʻau. ʻOi aku ka uku o nā Generics ma mua o nā inoa inoa inoa inoa.

ʻO ke kumu kūʻai maʻamau ʻo Tecfidera lāua ʻo Gilenya. ʻO ka nui maoli āu e uku ai e pili ana i kāu hoʻolālā ʻinikua.

Tecfidera vs. interferon (Avonex, Rebif)

Hoʻohui ʻia ʻo Tecfidera a me interferon (Avonex, Rebif) ma ke ʻano he hoʻoponopono hoʻoponopono hoʻololi maʻi. Hoʻoiho lāua i kekahi mau hana pale o ke kino, akā hana lākou i nā ʻano like ʻole.

Hoʻohana

ʻO Tecfidera a me interferon (Avonex, Rebif) i ʻae ʻia i kēlā me kēia FDA no ka mālama ʻana i nā ʻano relapsing o nā sclerosis (MS) he nui.

Nā ʻano lāʻau

ʻO kahi keu pono o Tecfidera ka mea i lawe ʻia e ka waha. Hele mai ʻo Tecfidera ma ke ʻano he lohi-hoʻokuʻu i ka capsule waha i lawe ʻia i ʻelua mau lā i kēlā me kēia lā.

ʻO Avonex lāua ʻo Rebif nā inoa inoa ʻokoʻa ʻelua o interferon beta-1a. Pono e hoʻopili ʻia i nā ʻano ʻelua. Hele mai ʻo Rebif ma ke ʻano he subcutaneous injection i hāʻawi ʻia ma lalo o ka ʻekolu mau manawa i kēlā me kēia pule. Hele mai ʻo Avonex ma ke ʻano he intramuscular injection i hāʻawi ʻia i loko o kahi mākala i kēlā me kēia pule. Hoʻokele ʻia lāua ʻelua ma ka home.

Nā hopena a me nā pilikia

Loaʻa iā Tecfidera a me interferon kekahi mau ʻaoʻao a ʻokoʻa kekahi. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Ka hoʻokō ʻana

Kūpono nā Tecfidera a me interferon no ka mālama ʻana iā MS. ʻAʻole i hoʻohālikelike pololei ʻia ka maikaʻi o kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, e like me kahi kālailai, ʻoi aku ka maikaʻi o kā Tecfidera ma mua o interferon no ka pale ʻana i ka hoʻi hou ʻana a me ka lohi o ka hōʻino ʻana o ke kīnā.

Nā kumukūʻai

Loaʻa ʻo Tecfidera a me interferon (Rebif, Avonex) ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole loaʻa nā mana generic o kēia mau lāʻau. ʻOi aku ka uku o nā Generics ma mua o nā inoa inoa inoa inoa.

ʻO ke kumukūʻai maʻamau ʻo Tecfidera a me interferon. ʻO ka nui maoli āu e uku ai ma kāu ʻinikua.

ʻO Tecfidera vs. Protandim

ʻO Tecfidera kahi lāʻau i ʻae ʻia e ka FDA no ka mālama ʻana i nā ʻano relapsing o nā sclerosis (MS) he nui. Ua hōʻike ʻia kekahi mau noiʻi hoʻokolohua hiki iā ia ke pale i ka hoʻi hou ʻana o MS a me ka lohi o ka hōʻino ʻana o ke kino kīnā.

ʻO Protandim kahi mea hoʻopihapihaʻai i loaʻa nā mea hoʻohui, e like me:

• kakalaioa waiū
• ashwagandha
• kī ʻōmaʻomaʻo
• kuhukukū
• bacopa

Wahi a kekahi e hana ana ʻo Protandim e like me kā Tecfidera hana. Kāhea ʻia ʻo Protandim i kekahi manawa he "Tecfidera kūlohelohe."

Eia naʻe, ʻaʻole i aʻo ʻia ʻo Protandim i ka poʻe me MS. No laila, ʻaʻohe noiʻi noiʻi pono e hana.

Kaha: Inā ua kau kauka iā Tecfidera nāu, mai hoʻololi iā ia iā Protandim. Inā makemake ʻoe e ʻimi i nā koho lapaʻau ʻē aʻe, e kamaʻilio me kāu kauka.

Tecfidera lāʻau kō

Hōʻike ka ʻikepili aʻe i nā lāʻau i hoʻohana pinepine ʻia a koi ʻia paha. Eia nō naʻe, e mālama pono i nā lāʻau a ke kauka i kuhikuhi ai nāu. E hoʻoholo kāu kauka i ke ana ʻoi loa e kūpono i kāu mau pono.

Nā hana no nā sclerosis he nui

Ke hoʻomaka ʻo Tecfidera, 120 mg ka pālua i kēlā me kēia lā no nā lā ʻehiku. Ma hope o kēia pule mua, hoʻonui ʻia ka mahele i 240 mg ʻelua mau lā i kēlā me kēia lā. ʻO kēia ka lāʻau mālama mālama wā lōʻihi.

No ka poʻe i loaʻa nā hopena pilikia mai Tecfidera, hiki ke hoʻoliʻiliʻi manawa ʻia ka mālama ʻana i 120 mg ʻelua mau lā i kēlā me kēia lā. ʻO ke ana mālama kiʻekiʻe o 240 mg ʻelua mau manawa i kēlā me kēia lā e pono e hoʻomaka hou i loko o ʻehā mau pule.

He aha inā e haʻo wau i kahi lāʻau?

Inā haʻalele ʻoe i kahi lāʻau, lawe iā ia ke hoʻomanaʻo ʻoe. Inā kokoke i ka manawa no kāu kau ma hope, e lawe wale i kēlā lāʻau. Mai hoʻāʻo e hopu i ka lawe ʻana i ʻelua mau lāʻau i ka manawa hoʻokahi.

Pono wau e hoʻohana i kēia lāʻau lōʻihi?

ʻAe, manaʻo ʻia kēia lāʻau e lawe i kahi wā lōʻihi.

Pehea e lawe ai iā Tecfidera

Lawe pololei iā Tecfidera e like me nā kuhikuhi a kāu kauka.

Manawa

Lawe ʻia ʻo Tecfidera i ʻelua mau lā i kēlā me kēia lā. Lawe mau ʻia me ka ʻaina kakahiaka a me ka ʻaina ahiahi.

Lawe iā Tecfidera me ka meaʻai

Lawe ʻia ʻo Tecfidera me ka meaʻai. Hiki i kēia ke kōkua i ka hōʻemi ʻana i ka hopena ʻaoʻao. Hiki ke hoʻemi ʻia ka holoi ʻana ma ka lawe ʻana i 325 mg o ka aspirin 30 mau minuke ma mua o ka lawe ʻana iā Tecfidera.

Hiki iā Tecfidera ke haki?

ʻAʻole pono e haki ʻo Tecfidera, a wehe paha a pīpī ʻia i ka meaʻai. Pono e ale ʻia nā capsule Tecfidera āpau.

Hāpai a me Tecfidera

Hōʻike nā haʻawina holoholona e weliweli paha ʻo Tecfidera i kahi ʻōpū a ʻaʻole palekana e lawe i ka wā hāpai. Eia naʻe, ʻaʻole wānana pinepine nā noiʻi holoholona i nā mea e hiki i nā kānaka.

ʻAʻole i loiloi nā noiʻi i nā hopena o Tecfidera e pili ana i ka hāpai ʻana a i ʻole nā ​​kīnā hānau i nā kānaka.

Inā hāpai ʻoe a hoʻolālā paha ʻoe e hāpai, e kamaʻilio me kāu kauka inā pono ʻoe e lawe iā Tecfidera.

Inā hāpai ʻoe i ka lawe ʻana iā Tecfidera, hiki iā ʻoe ke komo i loko o ka Tecfidera Pregnancy Registry. Kōkua kahi papa inoa hāpai i ka ʻohi ʻana i ka ʻike e pili ana i ka hopena o kekahi mau lāʻau i ka hāpai keiki. Inā makemake ʻoe e hui pū i ka papa inoa, e nīnau i kāu kauka, e kāhea iā 866-810-1462, a i ʻole kipa i ka pūnaewele o ka papa inoa.

ʻO Breastfeeding a me Tecfidera

ʻAʻole lawa nā noiʻi e hōʻike ai inā paha e ʻike ʻia ʻo Tecfidera i ka waiū umauma.

Paipai kekahi mau loea i ka hōʻalo ʻana i ka hānai ʻana iā ʻoe me ka lawe ʻana i kēia lāʻau. Eia naʻe, ʻaʻole na haʻi. Inā lawe ʻoe iā Tecfidera a makemake ʻoe e hānai i kāu keiki, e kamaʻilio me kāu kauka e pili ana i nā pilikia a me nā pono kūpono.

Pehea e hana ai ʻo Tecfidera

Multiple sclerosis (MS) kahi maʻi autoimmune. Me kēia ʻano o ke ʻano, ka ʻōnaehana pale kaua, ka mea e hakakā i ka maʻi, kuhi hewa i nā pūnaewele olakino no ka poʻe ʻenemi e hoʻouka kaua iā lākou. Hiki i kēia ke kumu i ka mumū mau.

Me MS, manaʻo ʻia kēia mumū mau e hōʻino i nā nerve, me ka demyelination e kumu i nā hōʻailona MS he nui. Manaʻo ʻia ʻo oxidative stress (OS) i kumu e hōʻino ai i kēia. ʻO OS kahi kaulike ʻole o kekahi mau mole i kou kino.

Manaʻo ʻia ʻo Tecfidera e kōkua i ka mālama ʻana iā MS ma o ka hana ʻana i ke kino e hana i kahi protein i kapa ʻia ʻo Nrf2. Manaʻo ʻia kēia protein e kōkua hou i ke kaulike o ke kino o ke kino. ʻO kēia hopena, e kōkua i ka hōʻemi ʻana i nā pōʻino i hoʻokumu ʻia e ka mumū a me ka OS.

Hoʻohui ʻia, hoʻololi ʻo Tecfidera i kekahi o nā hana o ke kino pale o ke kino e hoʻoliʻiliʻi i kekahi mau pane inflammatory. Hiki iā ia ke pale i ke kino mai ka hoʻoulu ʻana i kekahi mau hunaola pale. Hiki i kēia mau hopena ke kōkua i ka hōʻemi ʻana i nā hōʻailona MS.

Pehea ka lōʻihi o ka hana?

E hoʻomaka koke ʻo Tecfidera e hana i loko o kou kino, akā hiki ke hala i mau pule e hiki ai i ka hopena piha.

ʻOiai e hana nei, ʻaʻole paha ʻoe e ʻike i ka hoʻomaikaʻi nui i kāu mau hōʻailona. ʻO kēia no ka mea e manaʻo nui ʻia e pale i nā hoʻi hou.

ʻO Tecfidera a me ka waiʻona

ʻAʻole pili ʻo Tecfidera me ka wai ʻona. Eia nō naʻe, hoʻonāukiuki paha ka waiʻona i kekahi mau hopena ʻē aʻe o Tecfidera, e like me:

• pāhoehoe
• nausea
• ʻōpala

Hōʻalo i ka inu ʻana i ka nui o ka waiʻona i ka wā e lawe ana iā Tecfidera.

Nā launa pū ʻo Tecfidera

Hiki paha iā Tecfidera ke launa pū me nā lāʻau ʻē aʻe. Aia ma lalo ka papa inoa o nā lāʻau i hiki ke launa pū me Tecfidera. ʻAʻole paha i loko o kēia papa inoa nā lāʻau āpau e launa pū me Tecfidera.

Hiki i nā launa lāʻau ʻokoʻa ke kumu i nā hopena like ʻole. ʻO kahi laʻana, hiki i kekahi ke hoʻopilikia i ka maikaʻi o ka hana ʻana o ka lāʻau, ʻoiai ʻo kekahi e hoʻonui i nā hopena ʻē aʻe.

Ma mua o ka lawe ʻana iā Tecfidera, e hoʻomaopopo pono e haʻi aku i kāu kauka a me ka kauka lāʻau e pili ana i nā kauka a pau, ma ka ʻaiʻē, a me nā lāʻau ʻē aʻe āu e lawe ai. E haʻi pū iā lākou e pili ana i nā wikamina, nā mea kanu, a me nā mea hoʻopiha āu e hoʻohana ai. Hiki ke kōkua i ka hāʻawi ʻana i kēia ʻike iā ʻoe e hōʻalo i nā launa ʻole.

Inā he mau nīnau kāu e pili ana i nā launa lāʻau e hoʻopili iā ʻoe, e nīnau i kāu kauka a kauka paha.

ʻO Tecfidera a me ocrelizumab (Ocrevus)

Lawe iā Tecfidera me ka ocrelizumab hiki ke hoʻonui i ka makaʻu o ka pale pale maʻi a me ka hopena i nā maʻi ʻino. ʻO Immunosuppression ke hoʻonāwaliwali ʻia ka ʻōnaehana pale.

ʻO Tecfidera a me ibuprofen

ʻAʻohe mau pilina i ʻike ʻia ma waena o ibuprofen a me Tecfidera.

ʻO Tecfidera a me ka aspirin

ʻAʻohe mau pilina i ʻike ʻia ma waena o aspirin a me Tecfidera. Hoʻohana mau ʻia ʻo Aspirin 30 mau minuke ma mua o ka lawe ʻana iā Tecfidera e pale ai i ka holoi ʻana.

Nā nīnau e pili ana iā Tecfidera

Eia nā pane i kekahi mau nīnau e nīnau pinepine ʻia e pili ana iā Tecfidera.

No ke aha e kumu ai ʻo Tecfidera i ka flush?

ʻAʻole maopopo maopopo ke kumu o Tecfidera kumu i ka flush. Eia naʻe, pili paha ia i ka dilation (widening) o nā kīʻaha koko i ka maka kahi e loaʻa ai ka flushing.

Pehea e hiki ai iā ʻoe ke pale i ka hoʻoheheʻe ʻana mai Tecfidera?

ʻAʻole hiki iā ʻoe ke pale holoʻokoʻa i ka holoi ʻia ʻana e Tecfidera, akā aia ʻelua mau mea hiki iā ʻoe ke hana e hōʻemi iā ia:

• Lawe iā Tecfidera me kahi pāʻina.
• Lawe i ka 325 mg aspirin 30 mau minuke ma mua o ka lawe ʻana iā Tecfidera.

Inā ʻaʻole kōkua kēia mau ʻanuʻu a loaʻa mau iā ʻoe ka flush, e kamaʻilio me kāu kauka.

Luhi paha ʻo Tecfidera iā ʻoe?

Wahi a kekahi poʻe e lawe iā Tecfidera manaʻo lākou i ka luhi. Eia nō naʻe, ʻaʻole nā ​​hopena o ka luhi a i ʻole hiamoe ka hopena i loaʻa i nā noiʻi olakino o Tecfidera.

He immunosuppressant ʻo Tecfidera?

Hoʻopili ka Tecfidera i ka ʻōnaehana pale. Hoʻoemi ia i kekahi o nā ʻōnaehana paleʻoniʻoni e hoʻoliʻiliʻi i nā pane lī. Hoʻoemi paha ia i ka hoʻoulu ʻana o kekahi mau hunaola pale.

Eia naʻe, ʻaʻole mahele maʻamau ʻo Tecfidera ma ke ʻano he immunosuppressant. Kapa ʻia ia i kekahi manawa he immunomodulator, ʻo ia hoʻi ka hopena i kekahi mau hana o ka ʻōnaehana pale.

Pono wau e hopohopo no ka puka ʻana o ka lā i ka lawe ʻana iā Tecfidera?

ʻAʻole hana ʻo Tecfidera i kou ʻili i ka lā e like me ka hana ʻana o kekahi lāʻau. Eia nō naʻe, inā ʻike ʻoe i ka kahe ʻana mai Tecfidera, hiki i ka lā ke hoʻomāhuahua i ka manaʻo flush.

Pehea ka maikaʻi o Tecfidera?

Ua loaʻa ʻo Tecfidera e hōʻemi i ka hoʻi hou ʻana o MS e kahi 49 kenetene i loko o ʻelua mau makahiki. ʻIke pū ʻia e hōʻemi i ka makaʻu o ka hōʻemi kino kīnā ʻana ma kahi o 38 pākēneka.

No ke aha he mau ʻaoʻao dosing ʻokoʻa kaʻu ma hope o ka pule mua?

He mea maʻamau ka hoʻomaka ʻana o nā lāʻau i kahi lāʻau haʻahaʻa a laila hoʻonui ʻia ma hope. ʻAe kēia i kou kino e hana i kahi mea haʻahaʻa ma muli o ka hoʻoponopono ʻana i ka lāʻau.

No Tecfidera, hoʻomaka ʻoe me kahi mahele haʻahaʻa o 120 mg i ʻelua mau lā i kēlā me kēia lā i nā lā ʻehiku mua. Ma hope o kēlā, hoʻonui ʻia ke ana i 240 mg i ʻelua mau manawa i kēlā me kēia lā, a ʻo kēia ke ana āu e noho ai. Eia nō naʻe, inā he nui nā hopena ʻē aʻe me nā mea ʻoi aku ke kiʻekiʻe, hiki i kāu kauka ke hoʻohaʻahaʻa i kāu mea hana no kekahi manawa.

Pono wau e kiʻi i nā hoʻokolohua koko ʻoiai au ma Tecfidera?

Ae. Ma mua o kou hoʻomaka ʻana i ka lawe ʻana iā Tecfidera, e hana ana kāu kauka i nā hoʻokolohua koko e nānā i ka helu o kou aʻa koko a me kāu hana ate. E hana hou paha kēia mau hoʻokolohua i kou wā e lapaʻau ai me ka lāʻau. No ka makahiki mua o ka mālama ʻana, hana pinepine ʻia kēia mau hoʻāʻo ma ka liʻiliʻi i kēlā me kēia ʻeono mahina.

ʻO Tecfidera overdose

ʻO ka lawe ʻana i ka nui o kēia lāʻau i hiki ke hoʻonui i kou makaʻi i nā hopena ʻino.

Nā hōʻailona overdose

Hiki i nā ʻōuli o ka overdose ke komo pū me:

• pāhoehoe
• nausea
• ʻōpala
• ka luaʻi
• hūwī
• hoʻohuhū ʻōpū
• ʻeha poʻo

He aha e hana ai inā he overdose

Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau, e kāhea i kāu kauka a i ʻole e ʻimi i ke alakaʻi mai ka ʻAmelika Hui Pū ʻIa Poison Control ma 800-222-1222 a i ʻole ma o kā lākou mea pono pūnaewele. Akā inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele koke i kahi lumi pilikia kokoke.

Nā ʻōlelo aʻoaʻo no Tecfidera

Ma mua o ka lawe ʻana iā Tecfidera, e kamaʻilio me kāu kauka e pili ana i nā kūlana olakino āu. ʻAʻole kūpono paha ʻo Tecfidera iā ʻoe inā loaʻa iā ʻoe kekahi ʻano olakino. Loaʻa kēia mau ʻano:

• Kaomi ʻōnaehana pale ʻole: Inā kāohi ʻia kāu ʻōnaehana pale maʻi, e hoʻonui paha ʻo Tecfidera i kēia ʻano. Hiki i kēia hopena ke hoʻonui i kou makaʻi i nā maʻi koʻikoʻi.
• Maʻi maʻi ate: Hiki iā Tecfidera ke hōʻeha i ke ake. Inā loaʻa ʻoe i ka maʻi akepaʻa, e hoʻomāhuahua paha ia i kou ʻano.

Pau ʻole ʻo Tecfidera

Ke hāʻawi ʻia ʻo Tecfidera mai ka hale kūʻai lāʻau, e hoʻohui ka kauka i kahi lā palena pau i ka lepili ma ka ʻōmole. ʻO kēia lā maʻamau hoʻokahi makahiki mai ka lā i hāʻawi ʻia ai ka lāʻau.

ʻO ke kumu o kēlā mau lā palena pau e hōʻoia i ka hopena o nā lāʻau i kēia manawa. ʻO ke kūlana o ka Food and Drug Administration (FDA) i kēia manawa e hōʻalo i ka hoʻohana ʻana i nā lāʻau i make. Eia naʻe, ua hōʻike ʻia kahi noiʻi a ka FDA he maikaʻi paha nā lāʻau he nui ma mua o ka lā palena pau i helu ʻia ma ka ʻōmole.

Pehea ka lōʻihi o ka maikaʻi o ka lāʻau e hiki ai ke hilinaʻi i nā kumu he nui, me ke ʻano a me kahi e mālama ʻia ai ka lāʻau. Pono e mālama ʻia ʻo Tecfidera i ka mahana o ka lumi i ka pahu kumu a pale ʻia mai ka mālamalama.

Inā loaʻa iā ʻoe kahi lāʻau i hoʻohana ʻole ʻia i hala i ka lā palena pau, e kamaʻilio me kāu kauka lāʻau e pili ana inā hiki paha iā ʻoe ke hoʻohana.

ʻO ka ʻike ʻoihana no Tecfidera

Hāʻawi ʻia ka ʻike aʻe no nā kauka lapaʻau a me nā ʻoihana ola.

Mekanism o ka hana

He paʻakikī ka ʻano hana o ka hana a Tecfidera a maopopo ʻole. Hana ia no nā sclerosis maha (MS) ma o nā hopena anti-inflammatory a me nā hopena antioxidant. ʻO ka hoʻāla a me ke koʻikoʻi oxidative i manaʻo ʻia he hana pathological koʻikoʻi i nā mea maʻi me MS.

Hoʻokomo ʻo Tecfidera i ka mea nukelea 1 (erythroid-i loaʻa 2) -like 2 (Nrf2) alahele antioxidant, ka mea e pale aku i ka hōʻino ʻana i nā oxidative i loko o ka ʻōnaehana nūnū a hoʻemi i ka demyelination nerve.

Hoʻopili pū ʻo Tecfidera i nā ala pale pale lehulehu e pili ana i nā receptor like tol, kahi e hoʻēmi ai i ka hana cytokine inflammatory. Hoʻoemi ka Tecfidera i ka hoʻoulu ʻana i nā pūnaewele T immune.

Pharmacokinetics a me ka metabolism

Ma hope o ka lawelawe waha ʻana o Tecfidera, wikiwiki ia e ka esterases i kāna metabolite hana, monomethyl fumarate (MMF). No laila, ʻaʻole hiki ke helu ʻia ka dimethyl fumarate i ka plasma.

ʻO ka manawa i MMF hoʻonui nui (Tmax) ʻo 2-2.5 mau hola.

ʻO ka exhalation o carbon dioxide ke kuleana no ka hoʻopau ʻana i 60 pākēneka o ka lāʻau. ʻO nā hōʻoki hōʻino a me ka fecal nā ala liʻiliʻi.

ʻO ka hapalua o ke ola o MMF ma kahi o 1 hola.

Nā Kūʻai Kūʻai

Kūleʻa ʻia ʻo Tecfidera i nā mea maʻi me kahi hypersensitivity i ʻike ʻia e dimethyl fumarate a i ʻole nā ​​mea loaʻa.

Waihona

Pono e mālama ʻia ʻo Tecfidera i ka mahana wela, 59 ° F a 86 ° F (15 ° C a 30 ° C). Pono e mālama ʻia i loko o ka pahu kumu a pale ʻia mai ka kukui.

Ke kuhikuhi nei i ka ʻike

Hiki ke loaʻa nā ʻike kuhi Tecfidera piha ma aneʻi.

Hoʻolaha: Ua hana ʻo MedicalNewsToday i nā hana āpau e hōʻoia i ka pololei, ka laulā, a me ka lā hou o nā ʻike āpau. Eia nō naʻe, ʻaʻole pono e hoʻohana i kēia ʻatikala i pani no ka ʻike a me ka mākaukau o kahi loea mālama ola laikini. E nīnau mau ʻoe i kāu kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka lawe ʻana i nā lāʻau. Hiki ke loli i ka ʻike o ka lāʻau i loko a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana a pau, nā kuhikuhi, ka mālama ʻana, nā ʻōlelo aʻoaʻo, nā launa lāʻau, nā hopena maʻi ʻaʻai, a me nā hopena maikaʻi ʻole. ʻO ka loaʻa ʻole o nā ʻōlelo aʻoaʻo a i ʻole nā ​​ʻike ʻē aʻe no kahi lāʻau i hāʻawi ʻia ʻaʻole ia e hōʻike i ka palekana o ka lāʻau a lāʻau paha i kūpono no nā mea maʻi āpau a i ʻole nā ​​hoʻohana kikoʻī āpau.