Nā Steroids no ka mālama ʻana i ka Rheumatoid Arthritis
Anter
- Hōʻike Overview
- ʻO ka ʻike ākea e pili ana i nā steroid no RA
- Nā steroid ʻo oral no RA
- Nā hana
- Nā kōkuhi steroid no RA
- Nā hana
- ʻO nā steroid ʻo Topical no RA
- Nā pilikia o ka hoʻohana ʻana i nā steroid no RA
- Nā hopena o nā steroid
- ʻO ka lawe lawe ʻana
Hōʻike Overview
ʻO Rheumatoid arthritis (RA) kahi maʻi līlū mau loa e hōʻeha, pehu, a ʻoʻoleʻa hoʻi i nā hono liʻiliʻi o kou mau lima a me kou mau wāwae. He maʻi holomua ia ʻaʻohe ona lāʻau. Me ka ʻole o ka lapaʻau ʻana, hiki i ka RA ke alakaʻi i ka luku pū ʻia a me ke kīnā ʻole.
Hoʻomaha ka hōʻoia mua a me ka mālama ʻana i nā ʻōuli a hoʻomaikaʻi i kou ola me RA. Pili ka mālama iā ʻoe iho. Hoʻohui pinepine nā papa hana hoʻomaʻamaʻa i nā lāʻau antirheumatic-modifying maʻi (DMARD) i hui pū ʻia me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs), a me nā steroid haʻahaʻa. Loaʻa i nā ʻano lāʻau ʻē aʻe, e like me ka hoʻohana ʻia o ka antibiotic minocycline.
E nānā pono i ka hana a nā steroid i ka mālama ʻana iā RA.
ʻO ka ʻike ākea e pili ana i nā steroid no RA
Kapa ʻia ʻenehana ʻo Steroids he corticosteroids a i ʻole glucocorticoids. ʻO lākou nā synthetic synthetic e like me ka cortisol, kahi hormone e hana maʻamau ai kāu mau adrenal adrenal. Ma mua o 20 mau makahiki i hala aku, ʻo nā steroid ka lapaʻau maʻamau no RA.
Akā ua loli kēia mau kūlana i ka ʻike ʻia ʻana o nā hopena weliweli o nā steroid a i ka hoʻomohala ʻia ʻana o nā ʻano lāʻau hou. ʻO nā kulekele RA o kēia manawa ʻO ke Kulanui ʻAmelika o Rheumatology e ʻōlelo i kēia manawa i nā kauka e hoʻohana i ka hapa haʻahaʻa o nā steroid no ka manawa pōkole loa.
Hiki ke lawe waha ʻia nā Steroids, e ka injection, a i ʻole noi ʻia topically.
Nā steroid ʻo oral no RA
Hele mai nā steroid oral i ka pila, ka capsule, a i ʻole ke ʻano wai. Kōkua lākou i ka hoʻohaʻahaʻa i nā pae mai loko o kou kino e pehu, paakiki, a ʻeha hoʻi kou mau ami. Kōkua pū lākou i ka hoʻoponopono ʻana i kāu ʻōnaehana autoimmune e kāpae i nā ahi uila. Aia kekahi mau hōʻike e hōʻemi ana nā steroid i ka hōʻino ʻana o ka iwi.
ʻO nā ʻano steroid maʻamau i hoʻohana ʻia no RA e:
- prednisone (Deltasone, Sterapred, Liquid Pred)
- hydrocortisone (Cortef, A-Hydrocort)
- prednisolone
- dexamethasone (Dexpak Taperpak, Decadron, Hexadrol)
- methylprednisolone (Depo-Medrol, Medrol, Methacort, Depopred, Predacorten)
- triamcinolone
- dexamethasone (Decadron)
- betamethasone
ʻO Prednisone ka steroid i hoʻohana pinepine ʻia i ka mālama RA.
Nā hana
Hiki ke kuhikuhi ʻia kahi lāʻau haʻahaʻa o nā steroid oral no RA mua, me DMARD a i ʻole nā lāʻau ʻē aʻe. ʻO kēia no ka mea lawe nā DMARD 8-12 mau wiki e hōʻike i nā hopena. Akā hana wikiwiki nā steroid, a ʻike ʻoe i ko lākou hopena i kekahi mau lā. Kuhi ʻia nā Steroids i kekahi manawa ma ke ʻano he "bridge bridge."
Ma hope o ka lilo ʻana o nā lāʻau ʻē aʻe i mea pono, pono ia e hoʻopau i nā steroid. Hana mālie kēia i nā hoʻonui ʻana o. Kōkua ka taping i ka pale ʻana i nā hōʻailona haʻalele.
ʻO ka mahele maʻamau o ka prednisone he 5 a 10 mg i kēlā me kēia lā. Paipai ʻia ʻaʻole ʻoe e lawe ma mua o 10 mg i kēlā me kēia lā o prednisone. Hāʻawi ʻia i ʻelua mau kaha o kēlā me kēia.
ʻO ka maʻamau, lawe ʻia nā steroid i ke kakahiaka ke ala ʻoe. ʻO kēia ka manawa e hana ai nā steroid o kou kino ponoʻī.
ʻO nā mea hoʻopihapiha o ka calcium () a me ka wikamina D () me nā steroid.
Hiki ke hoʻohana ʻia kahi mahele lāʻau ʻoi loa o nā steroid i RA inā aia nā pilikia koʻikoʻi.
Ua ʻike ʻia kahi loiloi 2005 o ka ʻikepili RA he 20 a 40 paha pākēneka o ka poʻe i ʻike hou ʻia me RA e hoʻohana nei i nā steroid. Ua ʻike pū ʻia ka loiloi a hiki i ka 75 pākēneka o ka poʻe me RA i hoʻohana i nā steroid i kekahi manawa.
I kekahi mau hihia, ʻo ka poʻe me ka ʻino (i kapa ʻia he disabling) RA e lilo i ka hilinaʻi i ka wā lōʻihi o ka steroid i mea e hana ai i nā hana o kēlā me kēia lā.
Nā kōkuhi steroid no RA
Hiki i nā kauka lāʻau ke ʻāpono pono ʻia e kāu kauka i loko o nā hono a me kahi e kokoke ana iā lākou no ka ʻeha a me ka hanu ʻana. Hiki ke hana i kēia ke mālama nei ʻoe i kāu lāʻau lapaʻau lāʻau ʻē aʻe i kuhikuhi ʻia.
Kuhi ke Kulanui ʻAmelika o Rheumatology i ka wanaʻao RA, hiki i nā injection steroid i loko o nā hono i pili nui ke hāʻawi i kahi kōkua kūloko a i kekahi manawa. Kupanaha paha kēia hoʻomaha, akā ʻaʻole mau ia.
I kekahi mau hihia, aia nā injection steroid i ka hoʻemi ʻana i ka nui o RA nodule. Hāʻawi kēia i kahi koho ʻē aʻe i ke kahakaha.
Paipai ʻia ʻaʻole e hana i nā kuʻi ʻana i ka mea like ma mua o hoʻokahi manawa i loko o ʻekolu mau mahina.
Nā hana
ʻO nā steroid i hoʻohana mau ʻia no ka hoʻopili ʻana he methylprednisolone acetate (Depo-Medrol), triamcinolone hexacetonide, a me triamcinolone acetonide.
Hiki paha i kāu kauka ke hoʻohana i kahi anesthetic kūloko ke hāʻawi iā ʻoe i kahi injection steroid.
ʻO ka mahele o ka methylprednisolone maʻa mau 40 a 80 mg i ka milliliter. E loli paha ka mahele lāʻau ma muli o ka nui o ka ami e ʻimi ʻia ana. ʻO kahi laʻana, koi paha i kou kuli i ka lāʻau nui, a i 80 mg. Akā pono paha i kou kuʻe lima he 20 mg wale nō.
ʻO nā steroid ʻo Topical no RA
ʻO nā steroid topical, nā lāʻau āpau a me nā lāʻau i kuhikuhi ʻia, hoʻohana pinepine ʻia e ka poʻe me ka maʻi kōpaʻa no ka ʻeha ʻeha kūloko. Akā ʻaʻohe koi ʻia nā steroid topical (a i ʻōlelo ʻia paha) i ke alakaʻi ʻAmelika Hui Pū ʻIa o Rheumatology RA.
Nā pilikia o ka hoʻohana ʻana i nā steroid no RA
Hoʻohana ʻo Steroid i ka mālama ʻana ʻo RA ma muli o nā pilikia i kākau ʻia.
ʻO nā pilikia nui pū kekahi:
- Maʻi hohola: ʻO ka loiloi 2013 o ka poʻe i ʻike ʻia me RA a me ka lawe ʻana i nā steroid i loaʻa i kahi 68 pakeneka i hoʻonui i ka makaʻu no ka puʻuwai puʻuwai. Ua komo ka noiʻi i 8,384 poʻe i ʻike ʻia me RA ma waena o 1997 a me 2006. Kēlā me kēia 5 mg i kēlā me kēia lā e hoʻonui i nā ana i hoʻohui ʻia i ka makaʻu.
- Osteoporosis: i hoʻokomo ʻia e ka hoʻohana steroid ʻoi loa kahi pilikia nui.
- Ka make ʻana: Hōʻike kekahi mau noiʻi nānā e hoʻonui ʻia ka make me ka hoʻohana steroid.
- Kālepaʻa
- Diabetes
Hoʻonui ka pilikia i ka hoʻohana wā lōʻihi a me nā kau kiʻekiʻe.
Nā hopena o nā steroid
Nā hopena ʻaoʻao mai ka hoʻohana steroid i RA lawelawe me:
- hoʻonui i ka makaʻu o ka maʻi koʻohune a viral paha
- loaʻa kaupaona
- helehelena poepoe, kapa ʻia hoʻi he "alo o ka mahina"
- hoʻonui ke kō kō
- kahe koko kiʻekiʻe
- hoʻohaunaele ʻano, me ke kaumaha a me ka hopohopo
- ʻōlohelohe
- pehu wāwae
- paopao maʻalahi
- kiʻekiʻe prevalence o nā haki
- lawa adrenal
- hoʻohaʻahaʻa ʻia ka nui o ka mineral iwi i ʻelima mau mahina ma hope o ke kaʻina hana o 10 prednisone 10 mg
He kakaikahi nā hopena ʻaoʻao steroid a he manawa pōkole hoʻi. Pākuʻi ʻia kēia mau mea:
- hoʻonāukiuki ʻili
- hopena maʻi ʻaʻai
- lahilahi ʻili
E launa me kāu kauka ke hoʻopilikia ʻia nā hopena a kū ʻole paha. Nānā i kāu kō kō inā loaʻa ka maʻi diabetes.
ʻO ka lawe lawe ʻana
Hiki i nā Steroids i nā lāʻau haʻahaʻa ke lilo i ʻāpana o kahi hoʻolālā mālama no RA e hōʻoluʻolu i nā ʻōuli. Hana wikiwiki lākou e hōʻoluʻolu i ka pehu a me ka ʻeha. Akā e noʻonoʻo pono ʻoe i nā makaʻi i ʻike ʻia o ka hoʻohana steroid, ʻoiai ma kahi haʻahaʻa.
E heluhelu aʻe ma nā mea hiki ke mālama ʻia, e like me nā biologics a me ka minocycline antibiotic. Kaupaona i nā pluses a me nā minus o kēlā me kēia lapaʻau a me nā hoʻohuihui lāʻau.Kūkākūkā me nā kauka lapaʻau hiki ke hiki me kāu kauka, a e ʻike pono e pane ʻia kāu mau nīnau āpau.
Ma luna aʻe o nā mea āpau, koi ka lāʻau RA iā ʻoe e eleu.