Hemolytic Uremic Syndrome: he aha ia, nā kumu a me ka mālama ʻana

Anter

• Nā kumu nui
• Nā ʻōuli o Hemolytic Uremic Syndrome
• Kānāwai o HUS
• Pehea e hana ai i ka lāʻau

ʻO Hemolytic Uremic Syndrome, a i ʻole HUS, kahi maʻi i hōʻike ʻia e ʻekolu mau hōʻailona nui: hemolytic anemia, hōʻeha ākea a me ka thrombositopenia, e kūlike me ka hoʻemi o ka nui o nā platelet i ke koko.

ʻOi aku ka maʻalahi o kēia maʻi i nā keiki ma muli o ka ʻai ʻana o nā meaʻai i hoʻohaumia ʻia e nā bacteria e like me Escherichia coli, akā hiki nō ke hana i nā mākua ma muli o ka maʻi a me nā hopena o nā hanana ʻē aʻe, e like me hypertension a scleroderma, no ka laʻana.

Nā kumu nui

ʻO ke kumu nui o HUS, keu hoʻi i nā keiki, he maʻi ia na ʻO Escherichia coli, Salmonella sp., a i ʻole ʻO Shigella sp., ʻo ia nā bacteria i hiki ke hoʻokuʻu i nā toxins i loko o ke kahe o ke koko a alakaʻi i ka hoʻokumu ʻana o ka thrombi liʻiliʻi i loko o nā moku, e hopena i ka luku ʻia o nā hunaola ʻulaʻula a me nā ʻino puʻupaʻa. Hana maʻamau kēia ʻano maʻi ma o ka ʻai ʻana i nā meaʻai i hoʻohaumia ʻia e kēia mau microorganism, no laila, he mea nui e nānā i ka hoʻomaʻemaʻe pilikino a me ka meaʻai. Maopopo ke ʻano o ka maʻemaʻe o ka meaʻai.

ʻOiai ʻoi aku ka maʻamau o nā keiki, hiki i ka Hemolytic Uremic Syndrome ke kū i ka poʻe mākua, a hiki ke kumu ʻia i ka ʻai ʻana i nā meaʻai i hoʻoweliweli ʻia e nā bacteria, a me nā hopena o nā kūlana ʻē aʻe, e like me ka maikaʻi ʻole o ka hakuʻala postpartum, scleroderma, maʻi maʻi HIV a me antiphospholipid syndrome, ʻo kahi laʻana.

Nā ʻōuli o Hemolytic Uremic Syndrome

ʻO nā ʻōuli mua o HUS ua like ia me gastroenteritis, me ke kuni, ke anuanu, ka maʻi pākī, ka luhi nui loa, ka luaʻi a me ka nāwaliwali. I ka wā o ka maʻi, ʻike ʻia nā ʻōuli ʻē aʻe, e like me:

• Hewa kōkea nui;
• Mimi liʻiliʻi;
• ʻO Jaundice;
• Ke kū nei o ke koko i ka mimi a me nā ʻāpana;
• Pallor;
• ʻIke o nā kiko poni ma ka ʻili;
• ʻO Jaundice.

ʻOiai ʻike ʻole ʻia, aia nō paha ke ʻano o nā ʻōuli neurological, e like me ka hopu ʻana, ka huhū, ka ʻike ʻole a me ke koma, no ka laʻana. Eia hou, he mea nui e hoʻomaopopo ʻaʻole nā ​​hihia a pau o HUS i mua o ka maʻi palahū, a he mea nui ia i ke alo o kekahi hōʻailona e hōʻike ana i ka maʻi maʻi, hele ke kanaka i ke kauka e hana i ke kuhi a hoʻomaka i ka lāʻau. nā kūpikipiki e like me ka puʻuwai puʻuwai.

Kānāwai o HUS

Hana ʻia ke kuhi o HUS ma o ka loiloi ʻana i nā ʻōuli a me ka hopena o nā hoʻokolohua hoʻokolohua i noi ʻia e ke kauka, kahi i manaʻo ai e ʻike i nā ʻano nui ʻekolu o ka maʻi, ʻo ia ka hemolytic anemia, hoʻemi i ka helu platelet a me nā loli i ka hana o nā puʻupaʻa. .

No laila, noi pinepine ke kauka i ka hana o ka helu o ke koko, kahi e hōʻoia ai ka hoʻonui ʻana i ka nui o nā leukosit, ka hoʻemi ʻana i ka nui o nā platelet, nā ʻulaʻula a me nā hemoglobin, a me ke alo o schizocytes, nā ʻāpana. o nā hunaola ʻulaʻula e hōʻike ana i ka haki ʻana o kēia mau hunaola ma muli o kekahi kūlana, ka mea maʻa mau o ka thrombi. E aʻo pehea e wehewehe ai i ka helu o ke koko.

ʻO nā hoʻāʻo e loiloi i ka hana o ka hakuʻala, e like me ke ana o ka urea a me ka creatinine i loko o ke koko, ua noi ʻia, i hoʻonui ʻia i kēia kūlana. Eia hou, ke piʻi nei ka hoʻonui o ka bilirubin pili ʻole i ke koko a me ka LDH, ka mea e hōʻike pinepine nei i ka hemolysis microangiopathic, ʻo ia hoʻi, ke luku ʻia nā ʻula koko ʻulaʻula ma muli o ke alo o ka thrombi liʻiliʻi i loko o nā moku.

Ma waho aʻe o kēia mau hoʻāʻo, hiki i ke kauka ke noi i ka co-culture, kahi e kuhikuhi ai i ka bacteria e pili ana i ka maʻi, inā ʻo ia ka hihia, a pēlā e wehewehe ai i kahi lapaʻau maikaʻi loa e mālama ai iā HUS.

Pehea e hana ai i ka lāʻau

Hana ʻia ka lāʻau no Hemolytic Uremic Syndrome e hoʻoliʻiliʻi i nā ʻōuli a hāpai i ka hoʻopau ʻia ʻana o ka bacteria, inā kū ka maʻi ma muli o ka maʻi. No laila, he mea nui e inu i ka nui o nā wai e pale ai i ka make wai, me ka hoʻoliʻiliʻi o ka hōʻemi ʻana o ka protein i mea e pale aku ai i ka hōʻino ʻana i nā puʻupaʻa.

I kekahi mau hihia, hiki i ke kauka ke koi aku i ka hoʻohana ʻana i nā lāʻau ʻalopika e pale aku ai i ka maʻi a i ʻole ke kō ʻana o ke koko, i hōʻike pinepine ʻia no nā keiki i loaʻa i ka maʻi kōkō he hōʻailona. I nā hihia ʻoi aku ka paʻakikī, ʻo ia hoʻi, ke holo mua ka ʻeha o ka puʻupaʻa a loaʻa i ke kanaka nā ʻōuli o ka maʻi maʻi puʻuwai mau, pono ka dialysis a me ke kanu ʻana o ka puʻupaʻa, kahi e hoʻololi ʻia ai ka puʻupaʻa e kahi olakino ʻē aʻe. E ʻike pehea e hana ai i ka transplant kidney a pehea ke ʻano o ka post-operative.

I mea e pale aku ai iā SHU he mea nui e hōʻalo i ka ʻai ʻana i nā ʻiʻo maka a i ʻole ʻai ʻole, no ka mea ua haumia lākou, a me ka hōʻalo ʻana i nā meaʻai mai ka waiū i pasteurized ʻole ʻia, a me ka holoi lima ʻana i kou mau lima ma mua o ka hoʻomākaukau ʻana i ka meaʻai a ma hope o ka hoʻohana ʻana i ka lua.