ʻO ka loulou ma waena o Myeloma Multiple a me Kidney Failure

Anter

• He aha ka myeloma maha?
• Nā hopena o ka myeloma maha ma ke kino
• Hewa ʻole nā ​​hakuʻala
• Lilo iwi
• Anemia
• ʻŌnaehana pale nawaliwali
• Hypercalcemia
• Counteracting kidney hoʻokō ʻole
• Nānā wā lōʻihi

He aha ka myeloma maha?

ʻO ka myeloma maha he maʻi ʻaʻai ia e puka mai nā hunaola plasma. ʻO nā huna wai Plasma nā hunaola keʻokeʻo i loaʻa i ka iwi iwi. ʻO kēia mau pūnaewele kahi ʻāpana nui o ka ʻōnaehana pale. Hana lākou i nā mea ʻino e hakakā i ka maʻi.

Ulu koke nā hunaola plasma maʻi maʻi a lawe i ka iwi o ka iwi ma ka pale ʻana i nā hunaola maikaʻi mai kā lākou hana ʻana. Hana kēia mau pūnaewele i nā nui o nā protein āpau ʻole e hele a puni ke kino. Hiki iā lākou ke ʻike ʻia i ke kahe o ke koko.

Hiki ke ulu aʻe nā hunaola maʻi ʻaʻai i loko o nā tumors i kapa ʻia ʻo plasmacytomas. Kapa ʻia kēia ʻano myeloma he nui ke loaʻa nā helu he nui o nā hunaola i ka iwi iwi (> 10% o nā hunaola), a pili nā mea ʻē aʻe.

Nā hopena o ka myeloma maha ma ke kino

Hoʻopilikia ka ulu ʻana o nā hunaola myeloma i ka hana ʻana o nā hunaola plasma maʻamau. Hiki i kēia ke kumu i kekahi mau olakino olakino. ʻO nā ʻōpū i hoʻopili nui ʻia nā iwi, ke koko, a me nā puʻupaʻa.

Hewa ʻole nā ​​hakuʻala

ʻO ka maikaʻi ʻole o ka hakuʻala i ka myeloma maha he hana paʻakikī e pili ana i nā kaʻina hana a me nā ʻano hana. ʻO ke ala e hana ai kēia ʻo nā protein i hele ʻole i nā puʻupaʻa a waiho ma laila, e hana ana i ka ālai ʻana i nā tubula puʻupaʻa a me nā ʻano kānana i hoʻololi ʻia. Hoʻohui ʻia, hiki i nā pae calcium kiʻekiʻe ke hana i nā aniani i loko o nā puʻupaʻa, kahi e hōʻino ai. ʻO ka make wai, a me nā lāʻau e like me NSAID (Ibuprofen, naproxen) hiki ke hōʻeha i ka hakuʻala.

Ma waho aʻe o ka hōʻino ʻole o ka puʻupaʻa, ma lalo iho kekahi mau pilikia maʻamau mai ka myeloma maha:

Lilo iwi

Ma kahi o 85 pākēneka o ka poʻe i ʻike ʻia me ka myeloma he nui i ka nalo ʻana o ka iwi, e like me ka Multiple Myeloma Research Foundation (MMRF). ʻO nā iwi i hoʻopili pinepine ʻia ʻo ka iwi kuamoʻo, pelvis, a me nā iwi ʻaoʻao.

ʻO nā pūnaewele maʻi maʻi i loko o ka iwi iwi e pale i nā hunaola maʻamau mai ka hoʻoponopono ʻana i nā leona a i ʻole nā ​​kiko palupalu e hana i nā iwi. Hiki i ka hoʻemi ʻia o ka iwi ke alakaʻi i nā haki a me ke kaohi ʻana o ka iwi.

Anemia

Hoʻopilikia ka hana o ka cell plasma malignant me ka hana ʻana o nā ʻulaʻula ʻulaʻula a me keʻokeʻo maʻamau. Hana ʻia ke anemia ke haʻahaʻa ka helu o ke koko ʻulaʻula. Hiki iā ia ke kumu i ka luhi, ka liʻiliʻi o ka hanu, a me ka puʻupuʻu. Ma kahi o 60 pākēneka o ka poʻe me ka myeloma ʻike i ka anemia, e like me ka MMRF.

ʻŌnaehana pale nawaliwali

Paʻa ke kinipōpō keokeo i ka maʻi ma ke kino. Hoʻomaopopo a hoʻouka lākou i nā girus weliweli e hōʻeha i nā maʻi. ʻO nā helu nui o nā hunaola plasma ʻino i loko o ka iwi iwi ka hopena o nā helu haʻahaʻa o nā hunaola keokeo maʻamau. Haʻalele kēia i ke kino i ka maʻi.

ʻO nā mea ʻino maʻamau i hana ʻia e nā hunaola maʻi ʻole ʻaʻole kōkua i ka hakakā ʻana i ka maʻi. A hiki iā lākou ke loaʻa i nā meaola olakino olakino, e hopena ai i kahi ʻōnaehana pale nāwaliwali.

Hypercalcemia

ʻO ka nalo o ka iwi mai myeloma ke kumu o ka hoʻokuʻu ʻia ʻana o ka nui o ka puna i loko o ke kahe o ke koko. ʻO ka poʻe me nā iwi pūpū aia i ka nui o ka makaʻu o ka ulu ʻana i ka hypercalcemia.

Hiki ke kumu ʻia ʻo Hypercalcemia e nā gland parathyroid overactive. Hiki i nā hihia i hana ʻole ʻia ke alakaʻi i nā ʻōuli like ʻole e like me ka coma a i ʻole ka hopu ʻia o ka naʻau.

Counteracting kidney hoʻokō ʻole

Nui a hewahewa nā ala e hiki ai i nā puʻupaʻa ke mālama i ke olakino maikaʻi i ka poʻe me ka myeloma, keu hoʻi ke kiʻi koke ʻia ke ʻano. ʻO nā lāʻau i kapa ʻia nā bisphosphonates, hoʻohana pinepine ʻia e mālama i ka osteoporosis, hiki ke lawe ʻia e hōʻemi i ka iwi iwi a me ka hypercalcemia. Hiki i nā kānaka ke loaʻa i ka wai hoʻōla e hoʻōla hou i ke kino, i ka waha a i ʻole ke aniani.

ʻO nā lāʻau anti-inflammatory i kapa ʻia ʻo glucocorticoids hiki ke hōʻemi i ka hana o ke kelepona. A hiki i ka dialysis ke lawe i kekahi o nā kānana mai ka hana o ke kīhāpai. ʻO ka hope loa, hiki ke kaulike i ke kaulike o nā lāʻau i lawelawe ʻia i ka chemotherapy i mea e hōʻeha ʻole ai i nā puʻupaʻa.

Nānā wā lōʻihi

ʻO ka maikaʻi ʻole o ka hakuʻala he hopena maʻamau o ka myeloma maha. Hiki ke hōʻemi ʻia ka hōʻino ʻana i nā puʻupaʻa ke ʻike ʻia a mālama ʻia ke ʻano i kona wā mua. Loaʻa nā koho lapaʻau e kōkua i ka hoʻohuli i nā hōʻino ʻōpala i hoʻokumu ʻia e ka maʻi ʻaʻai.