Hiki iā Ketamine ke kōkua i ka hoʻohaʻahaʻa kaumaha?

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ʻOi aku ka maʻamau o ke kaumaha ma mua o kou manaʻo. Hoʻopilikia ia ma mua o 15 miliona ʻAmelika, a manaʻo ka World Health Organization e piʻi ana ka helu i 300 miliona ke hoʻonui ʻoe i ka honua. Loaʻa nā koho lapaʻau like ʻole e kōkua i ka hōʻemi ʻana i kāna mau ʻōuli-e noʻonoʻo i ka hopohopo, ka hiamoe ʻole, ka luhi, a me ka make ʻole o ka ʻai i waena o nā poʻe ʻē aʻe - me ka lapaʻau maʻamau ʻo nā serotonin reuptake inhibitors (a SSRIs paha). Akā mai ka makahiki 2000, ua hoʻāʻo nā kauka a me nā mea noiʻi me ka ketamine-ma mua he lāʻau lapaʻau hoʻomalu ʻeha, i kēia manawa i hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau ma ke alanui ma muli o kona mau hopena hallucinogenic-ʻo ia kekahi ala kūpono e mālama ai i ke ʻano, e like me ka Ruben Abagyan, Ph.D. , he loea lāʻau lapaʻau ma ke Kulanui o Kaleponi San Diego (UCSD).

Ke noʻonoʻo nei paha ʻoe, "Kali! He aha?" Inā ua lohe ʻoe i ka ketamine, i kapa ʻia ʻo Special K, ʻike ʻoe ʻaʻole ia he mea hoʻohenehene a i ʻole ka lāʻau OTC maʻamau. ʻO ka ʻoiaʻiʻo, ua ʻike ʻia ʻo ia he anesthetic dissociative (ʻo ia hoʻi he lāʻau lapaʻau e hoʻololi i ka ʻike o ka ʻike a me ke kani, ʻoiai e hoʻopuka ana i nā manaʻo maoli o ka hemo ʻana mai iā ʻoe iho a me ke kaiapuni). Hoʻohana nui ʻia ia e nā kauka lāʻau lapaʻau no ka mālama ʻana i ka ʻeha o nā holoholona, ​​akā hiki ke kuhikuhi ʻia i nā kānaka no ka mālama ʻehaʻeha ʻana, ʻo ia hoʻi nā mea me nā pilikia neuropathic, kahi ʻano ʻeha nerve mau, e like me kahi noi 2014 i paʻi ʻia ma ka Ka Nupepa Pelekane o Pharmacology.

"Ua ʻike ʻia ka pili ʻana o ka ʻeha a me ke kaumaha," wahi a Isaac Cohen, he haumāna lāʻau lapaʻau i hana i ka haʻawina. "ʻOi aku ka nui o ka poʻe kaumaha e noho i ka ʻeha a ʻoi aku ke kaumaha o ka poʻe i ka ʻeha mau loa ma muli o ka emi ʻana o ka neʻe ʻana, ka emi ʻana o ka hiki ke hoʻoikaika kino, a me nā kumu ʻē aʻe, ʻōlelo ʻo ia. ke kaumaha i ka manawa like, e alakaʻi ana i nā hopena maikaʻi aʻe no nā kūlana ʻelua.

I loko o ka mua-mau-nui-nui ana i kona ano, i paʻi 'ia ma Kūlohelohe, ua ʻike nā mea noiʻi i nā poʻe maʻi i loaʻa i ka ketamine i hōʻike i nā manawa haʻahaʻa o ke kaumaha. ʻO kēia noiʻi, i alakaʻi ʻia e ke Kula ʻo Pharmacy a me Pharmaceutical Sciences ma UCSD, hoʻoikaika i ka ʻikepili anecdotal a me nā noiʻi heluna liʻiliʻi i hōʻike pū i nā hopena antidepressive o ketamine.

He aha ka mea e hoʻokaʻawale ai i ka ketamine mai nā ʻano lāʻau ʻē aʻe, kikoʻī, i ka wikiwiki o ka hopena. "ʻO nā lapaʻau i ʻāpono ʻia e ka FDA i kēia manawa no ka luʻuluʻu ua hoka no nā miliona no ka mea ʻaʻole wikiwiki lākou e hana," wahi a Abaygan. Hana ʻo Ketamine i nā hola. ʻOi aku ka liʻiliʻi ma mua o nā SSRI, no ka laʻana, hiki ke lawe i ʻeono a ʻumi mau pule a hiki i ko lākou piha piha. A ʻo kēlā ʻokoʻa i ka manawa hiki ke lilo i mea no ke ola a i ʻole ka make, ʻoi aku hoʻi me ka poʻe e ʻike nei i nā manaʻo suicidal.

No kā lākou noiʻi ʻana, ua loiloi ʻo Abaygan a me kāna hui i ka ʻikepili mai ka System Report Report Adverse Event a FDA, kahi ʻoihana e ʻohiʻohi i ka ʻikepili e pili ana i nā hopena maikaʻi ʻole (a i ʻole nā ​​hopena i manaʻo ʻole ʻia o kēlā me kēia ʻano) o nā lāʻau i ʻae ʻia i hōʻike ʻia e nā kauka lāʻau lapaʻau a me nā kauka. Ma keʻano kūikawā, ua loaʻa iā lākou he 40,000 mau maʻi i kuhikuhi ʻia i ka lāʻau lapaʻau no ka ʻeha a hoʻokaʻawale iā lākou i ʻelua pūʻulu-ʻo ka poʻe i lawe i ka ketamine a me nā mea i mālama ʻia me nā lāʻau ʻeha ʻē aʻe (koe nā NSAID).

Ua hōʻike nā hopena i kahi "bonus" koʻikoʻi, ʻoiai ʻaʻole i manaʻo ʻia, ka hopena. ʻO ka hapalua o ka poʻe i mālama i ko lākou ʻeha me ka ketamine i hōʻike ʻia he emi ke kaumaha ma mua o ka poʻe i lawe i nā ʻano lāʻau hōʻemi ʻeha. ʻOiai ʻaʻole maopopo iā mākou inā paha kekahi o kēia mau maʻi, ʻo ia hoʻi ka poʻe ma ketamine, ke ʻike nei i nā hōʻailona depressive ma mua o ka lawe ʻana i nā meds, ka hopena maikaʻi i ka naʻau, a me ka pilina maʻamau ma waena o ka ʻeha a me ke kaumaha, hiki ke ʻōlelo hou e pili ana i ka hoʻohana ʻana o ketamine i. e mālama pono i ke kaumaha.

Wahi a ka poʻe noiʻi, ʻoi aku ka maʻalahi o ka ketamine a inā ua hoʻāʻo ʻoe ma mua o ʻekolu mau lāʻau antidepressant ʻē aʻe me ka kūleʻa ʻole, uhi ʻia ia e ka hapa nui o nā hoʻolālā ʻinikua olakino. He lae? Mai wikiwiki e kākau i ka ketamine ma ke ʻano he hallucinogen. He mea kūikawā paha ia ma hope o nā mea āpau. (A inā ʻaʻohe mea ʻē aʻe, e nā kāne, e nānā i kēia mau ala e hoʻokele ai i ke kaumaha a i ʻole ke kaumaha i kēlā me kēia manawa.)

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