Nintedanib

Anter

• Ma mua o ka lawe ʻana i nintedanib,
• Hoʻokumu paha ʻo Nintedanib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Nintedanib e mālama i ka fibrosis pulmonary idiopathic (IPF; ʻōpala o nā akemāmā me kahi kumu ʻike ʻole ʻia). Hoʻohana ʻia ia e mālama i kekahi ʻano o nā maʻi pulupulu fibrosing mau loa (ILD; kahi maʻi hoʻomau e hoʻonui ʻia ai ka scarring o nā akemāhā). Hoʻohana ʻia ʻo Nintedanib e hoʻolohi i ka helu o ka emi ʻana o ka hana o ka maʻi i nā poʻe me ka maʻi ʻōnaehana sclerosis i hoʻopili ʻia e pili ana (SSc-ILD; i ʻike ʻia ʻo ILD e pili ana i ka scleroderma: kahi maʻi kahi e ʻā ai nā ʻōhū e make pinepine ai. ). Aia ʻo Nintedanib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ka pale ʻana i ka hana o nā enzyme e pili ana i ka hopena ʻana i ka fibrosis.

Hele mai ʻo Nintedanib ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia me nā meaʻai i kēlā me kēia 12 hola (ʻelua manawa i ka lā). E lawe i napsanib capsule ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā nintedanib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā capsule a pau i ka wai; mai nahu a paopao iā lākou.

Pono paha kāu kauka e hōʻemi i kāu lāʻau a oki paha i ka lāʻau ʻana inā ʻike ʻoe i kekahi hopena ʻino loa. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i nintedanib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka nintedanib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsule nintedanib. E noi i kāu kauka lāʻau a nānā paha i ka ʻike hoʻomanawanui o ka mea hana no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E hōʻoia e haʻi i kekahi o kēia mau mea: anticoagulants ('' nā mea hōʻemi koko '') e like me warfarin (Coumadin, Jantoven); aspirin a me nā lāʻau anti-inflammatory nonsteroidal (NSAID) e like me ibuprofen (Advil, Motrin, a me nā mea ʻē aʻe) a me naproxen (Aleve, Anaprox, Naprelan); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); erythromycin (E.E.S., Ery-Tab, Eryc); ketoconazole; laxatives; nā steroid ʻo waha e like me dexamethasone (Decadron, Dexpak), methylprednisolone (Medrol), a me prednisone; phenytoin (Dilantin, Phenytek); pirfenidone (Esbriet); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); a palupalu paha ka pahu. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa ʻoe a i ʻole kekahi o kou ʻohana i kahi pilikia kahe o ke kahe, inā loaʻa a loaʻa paha ʻoe i ka ate a me ka maʻi puʻuwai, maʻi diverticular (diverticulitis; nā ʻeke liʻiliʻi i ka uhi o ka ʻōpū nui e hiki ai ke hoʻā ʻia), kahe koko, a inā he ʻoki koko hou kāu.
• e haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole hiki paha ke hāpai. ʻAʻole pono ʻoe e hoʻomaka i ka lawe ʻana i nintedanib a hiki i ka hōʻike ʻana o ka hāpai hāpai ua hōʻike ʻia ʻaʻole ʻoe hāpai. ʻAʻole ʻoe e hāpai i ka wā e lawe ana ʻoe i nintedanib; hōʻino paha ka lāʻau i kāu pēpē i hānau ʻole ʻia. Hiki i ka Nintedanib ke hoʻēmi i ka pono o nā kaola pale hormonal (nā lāʻau kaohi hānau, nā pāhoʻi, nā apo, nā implant, a i ʻole nā ​​injection), no laila ʻaʻole pono ʻoe e hoʻohana i kēia mau mea ma ke ʻano he ʻano hana wale no kou kaohi hānau. Pono ʻoe e hoʻohana i kahi ʻano pale o ka kaohi hānau (kahi mea e ālai i ka sperm mai ke komo ʻana i ka kōpū e like me ka condom a i ʻole diaphragm). E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o ka mālama ʻana a ma ka liʻiliʻi he 3 mau mahina ma hope o kāu mahele hope loa o ka nintedanib. Inā hāpai ʻoe i ka lawe ʻana i nintedanib, e kāhea koke i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū.
• e haʻi i kāu kauka inā hoʻohana ʻoe i nā huahana paka. Hiki i ka uahi paka ʻana ke hōʻemi i ka pono o kēia lāʻau. E hoʻōki ʻoe i ka puhipaka ma mua o kou hoʻomaka ʻana i ka nintedanib a hōʻalo i ka puhipaka i kāu mālama ʻana.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ʻoe e nalo i kahi lāʻau o nintedanib, e lele i ka lāʻau i hala ʻole a hoʻomau i kāu papa manawa maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Nintedanib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• hoʻēmi ʻai
• Kaumaha emi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• pāhoehoe
• luhi loa
• kahe koko ʻole ʻana a palapū paha
• nele i ka ikaika
• nalo ʻai ʻole
• ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
• melemele o ka ʻili a me nā maka
• mimi ʻeleʻele a ʻeleʻele (ti-kala)
• ʻeha ka umauma
• ʻeha ma kou mau lima, kua, ʻāʻī, a ʻāʻā
• pokole o ka hanu
• numbness a nāwaliwali paha ma kekahi ʻaoʻao o kou kino
• paʻakikī e ʻōlelo
• ʻeha poʻo
• ʻūpā
• nā palapū hoola ʻole
• ʻeha a pehu paha i kou wahi o ka ʻōpū, nausea, luaʻi, kuni, ke anu, a i ʻole ke koko i kāu stool
• hūwī
• ʻūlili

Hoʻokumu paha ʻo Nintedanib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua lab a ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i nintanib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Ofev^®