Herceptin - Hoʻoponopono Ka maʻi ʻaʻai umauma
Anter
He lāʻau lapaʻau ʻo Herceptin e pili ana i nā antibodies monoclonal, mai ke keʻena hoʻokolohua ʻo Roche, e hana pololei nei i ka pūnaeho maʻi ʻaʻai a maikaʻi loa i nā ʻano maʻi ʻaʻai.
Loaʻa ke kumukūʻai o kēia lāʻau lapaʻau ma kahi o 10 tausani reais a loaʻa ma SUS - Sistema Único de Saúde.
No ke aha ia
Hōʻike ʻia ʻo Herceptin no ka mālama ʻana i ka poʻe me ka maʻi ʻaʻai umauma metastatic, ka maʻi ʻaʻai mua a me ka maʻi ʻaʻai gastric kiʻekiʻe.
Pehea e ho ohana
Pono e lawelawe ʻia ʻo Herceptin e kahi ʻoihana ola kino:
1. Ka maʻi ʻaʻai umauma
Inā hoʻohana ʻia i kēlā me kēia pule, pono e mālama ʻia kahi mahele hoʻouka mua o 4 mg / kg kino kaumaha ma ke ʻano he infra intravenous ma luna o 90 mau minuke. ʻO nā mahele o ka pule ma hope he 2 mg / kg o ke kaumaha o ke kino, i hiki ke lawelawe ʻia i kahi infusion 30 mau minuke.
Inā hoʻohana ʻia i kēlā me kēia 3 mau pule, ʻo ka mahele hoʻouka mua he 8 mg / kg ke kaumaha o ke kino, a ukali ʻia e 6 mg / kg kino paona, i kēlā me kēia 3 mau pule, i nā infusions e pili ana i 90 mau minuke. Inā ʻae maikaʻi ʻia kēia lāʻau, hiki ke hoʻemi ʻia ka lōʻihi o ke infusion i 30 mau minuke.
Hiki ke lawelawe ʻia kēia lāʻau me ka paclitaxel a i ʻole ka docetaxel.
2. Ka maʻi ʻaʻai ʻōpū
Pono e hoʻohana i kēia lāʻau i kēlā me kēia pule he 3 a ʻo ka mahele hoʻouka mua he 8 mg / kg o ke kaumaha o ke kino, a ukali ʻia e 6 mg / kg o ke kaumaha o ke kino, pono e hana hou i kēlā me kēia 3 mau pule, i nā infusions mau ma kahi o 90 mau minuke. Inā ʻae maikaʻi ʻia kēia lāʻau, hiki ke hoʻemi ʻia ka lōʻihi o ke infusion i 30 mau minuke.
Nā hopena ʻē aʻe
ʻO nā hopena ʻē aʻe i hiki ke hana ʻia i ka wā o ka mālama ʻana me Herceptin he nasopharyngitis, maʻi, anemia, thrombositopenia, febrile neutropenia, hoʻemi ʻia ke keʻokeʻo koko keʻokeʻo, hoʻēmi a hoʻonui ʻia paha ke kaupaona, hoʻoliʻiliʻi ka makemake, ka hiamoe, pākī, poʻo, paresthesia, hypoesthesia, hoʻemi i ka ʻono. , haehae, conjunctivitis, lymphedema, wela uwila, pōkole o ka hanu, epistaxis, uā, runny ihu a me ka ʻeha o ka waha a me ka pharynx.
Hoʻohui, diarrhea, ka luaʻi, nausea, ʻeha o ka ʻōpū, maikaʻi ʻole ka digestion, constipation, stomatitis, erythema,hūwī, ka lauoho lauoho, nā maʻi kui a me ka ʻehaʻeha o nā mākala.
ʻO wai ka mea pono ʻole e hoʻohana
ʻAʻole pono e hoʻohana i kēia lapaʻau i nā poʻe i maʻi āpau i kekahi o nā ʻāpana o ka haʻilula, nā wahine hāpai a lactating.
ʻAʻole i hoʻāʻo ʻia kēia lāʻau i nā keiki, ka poʻe ʻōpio, ka poʻe ʻelemākule a me nā kānaka me ka hōʻeha puʻuwai a me ka hepatic, a pono e hoʻohana ʻia me ke akahele.