Loss lauoho a me testosterone

Anter

• Nā ʻano testosterone like ʻole
• Kinona ʻōhule
• DHT: ʻO ka hōmona ma hope o ka nalo ʻana o ka lauoho
• DHT a me nā kūlana ʻē aʻe
• ʻO kāu genes
• Nā Myths: Virility a me ka nalo ʻana o ka lauoho
• ʻO ka lauoho lauoho i nā wahine
• Nā mālama no ka nalo ʻana o ka lauoho

Ulana paʻakikī

ʻO ka pilina ma waena o ka testosterone a me ka nalo ʻana o ka lauoho he paʻakikī. ʻO kahi manaʻo kaulana i ka loaʻa ʻana o nā testosterone kiʻekiʻe i nā kāne ʻōhule, akā ʻoiaʻiʻo maoli nō kēia?

ʻO ke ʻōhule ʻōmaʻomaʻo kāne, a i ʻole androgenic alopecia, pili i kahi 50 miliona mau kāne a me 30 miliona mau wahine i United States, e like me ka National Institutes of Health (NIH). ʻO ka make ʻana o ka lauoho no ka shrinkage o nā follicle o ka lauoho a me ka hopena e hopena i ka pōʻai ulu. E lilo nā lauoho hou i mea ʻoi aku ka maikaʻi a maikaʻi a hiki i ka ʻole o ka lauoho i koe a lilo ka follicle i hiamoe. Hoʻokumu ʻia kēia nalo ʻana o ka lauoho e nā homone a me kekahi mau ʻāpana.

Nā ʻano testosterone like ʻole

Aia ka testosterone i kou kino i nā ʻano like ʻole. Aia ka testosterone "manuahi" ʻaʻole paʻa i nā protein i kou kino. ʻO kēia ke ʻano o ka testosterone e hiki ke hana ma waena o ke kino.

Hiki ke hoʻopaʻa ʻia ka testosterone i ka albumin, kahi protein i ke koko. ʻO ka hapa nui o ka testosterone paʻa i ka hormone-binding globulin (SHBG) protein a ʻaʻohe ʻeleu. Inā loaʻa kahi pae haʻahaʻa o SHBG, loaʻa paha iā ʻoe kahi pae kiʻekiʻe o ka testosterone manuahi i kou kahe koko.

Hana ʻia ʻo Dihydrotestosterone (DHT) mai ka testosterone e kahi enzyme. ʻO DHT he ʻelima mau manawa i ʻoi aku ka ikaika ma mua o ka testosterone. Hoʻohana mua ʻia ka DHT e ke kino i ka prostate, ka ʻili, a me nā follicle o ka lauoho.

Kinona ʻōhule

ʻO ke ʻōhule ʻōmaka kāne (MPB) he ʻano kūlike kona. Hōʻemi ka lauoho mua, i nā ʻaoʻao hoʻi, e hana ana i kahi ʻano M. ʻŌhule alo kēia. ʻO ke kalaunu o ke poʻo, ʻo ia hoʻi ka vertex, lilo pū i ke poʻo. ʻO ka hopena hoʻohui nā ʻāpana ʻelua i kahi ʻano "U". Hiki i ka MPB ke hoʻolōʻihi i ka lauoho o ka umauma, i hiki ke lahilahi i kou mau makahiki. Kupanaha, lauoho i nā wahi like ʻole ma ke kino hiki ke hana ʻokoʻa i nā loli hormonal. ʻO kahi laʻana, hiki i ka ulu ʻana o ka lauoho helehelena ke hoʻomaikaʻi a ʻo nā wahi ʻē aʻe e ʻōhule.

DHT: ʻO ka hōmona ma hope o ka nalo ʻana o ka lauoho

Hana ʻia ʻo Dihydrotestosterone (DHT) mai ka testosterone e kahi ʻenemema i kapa ʻia ʻo 5-alpha reductase. Hiki iā ia ke hana mai DHEA, kahi hormone i maʻa mau i nā wahine. Loaʻa ʻo DHT i ka ʻili, nā lauoho lauoho, a me ka prostate. ʻO nā hana a DHT a me ka noʻonoʻo o nā lauoho follicle i ka DHT ke kumu o ka nalo ʻana o ka lauoho.

Hana pū ʻo DHT i ka prostate. Me ka ʻole o DHT, ʻaʻole hoʻomohala maʻamau ka prostate. Me ka DHT nui loa, hiki i kahi kāne ke hoʻomohala i ka hypertrophy prostate benign, i ʻike ʻia he prostate hoʻonui ʻia.

DHT a me nā kūlana ʻē aʻe

Aia kekahi mau hōʻike o ka loulou ma waena o ka ʻōhule a me ka maʻi ʻaʻai prostate a me nā maʻi ʻē aʻe. Ua hōʻike ʻo Harvard Medical School he 1.5 mau manawa ka nui o nā kāne me ka ʻōhule vertex o ka hoʻomohala ʻana i ka maʻi ʻaʻai prostate ma mua o nā kāne me nā ʻōhule ʻole. ʻOi aku ka makaʻu o ka maʻi o ke aʻa coronary ma mua o 23 pākēneka kiʻekiʻe ma nā kāne me nā ʻōhule ʻōhule vertex. Ke hoʻomau nei nā noiʻi inā he loulou ma waena o nā pae DHT a me metabolic syndrome, diabetes, a me nā kūlana olakino ʻē aʻe.

ʻO kāu genes

ʻAʻole ka nui o ka testosterone a i ʻole DHT ke kumu o ke ohule; ʻo ia ka manaʻo nui o kou mau lauoho lauoho. Hoʻoholo ʻia kēlā ʻike e nā genetics. Hana ka ʻāpana AR i ka mea loaʻa ma nā lauoho lauoho e launa pū me testosterone a me DHT. Inā maʻalahi ka hopena o kāu mau receptor, ʻoi aku ka maʻalahi o ka hoʻonāukiuki ʻia e nā hapa liʻiliʻi o DHT, a ʻoi aku ka maʻalahi o ka lilo o ka lauoho i kahi hopena. Pākuʻi paha kekahi mau ʻāpana ʻē aʻe i kahi ʻāpana.

Hiki i ka makahiki, ke koʻikoʻi, a me nā kumu ʻē aʻe ke hoʻohuli inā ʻike ʻoe i ka nalo ʻana o ka lauoho. Akā he kuleana nui ko nā genes, a ʻo nā kāne he pili kāne kāne pili loa me MPB ka mea i ʻoi aku ka kiʻekiʻe o ka hoʻomohala ʻana iā MPB iā lākou iho.

Nā Myths: Virility a me ka nalo ʻana o ka lauoho

Nui a hewahewa nā kaʻao e pili ana i nā kāne ʻōhule. ʻO kekahi o lākou nā kāne me MPB ʻoi aku ka virile a ʻoi aku ka kiʻekiʻe o ka testosterone. ʻAʻole pono kēia ka hihia. Loaʻa i nā kāne me MPB ka pae haʻahaʻa o ka testosterone akā ʻoi aku ka kiʻekiʻe o ka enzyme e hoʻohuli i ka testosterone iā DHT. Ma kahi ʻokoʻa, loaʻa paha iā ʻoe nā genes e hāʻawi iā ʻoe i nā follicle o ka lauoho i maʻalahi i ka testosterone a i ʻole DHT.

ʻO ka lauoho lauoho i nā wahine

Hiki paha i nā wahine ke ʻike i ka nalo ʻana o ka lauoho ma muli o ka androgenetic alopecia. ʻOiai ʻoi aku ka haʻahaʻa o nā testosterone ma mua o nā kāne ma mua o ka hana ʻana o nā kāne, ua lawa ka mea e hiki ai ke lilo i ka lauoho androgenetic.

ʻIke ka wahine i kahi ʻano ʻokoʻa o ka nalo ʻana o ka lauoho. Hiki ke lahilahi ma luna o ka poʻo o ke poʻo i kahi kumu "lāʻau Kalikimaka," akā ʻaʻole e emi ke alo o ka lauoho mua. ʻO ka nalo lauoho lauoho wahine (FPHL) ma muli o nā hana a DHT ma nā follicle o ka lauoho.

Nā mālama no ka nalo ʻana o ka lauoho

ʻO kekahi mau ʻano hana o ka mālama ʻana iā MPB a me FPHL e pili ana i ka hoʻopilikia ʻana i nā hana a testosterone a me DHT. ʻO Finasteride (Propecia) kahi lāʻau e kāohi i ka 5-alpha reductase enzyme e hoʻohuli i ka testosterone i DHT. Weliweli ia e hoʻohana i nā wahine e hāpai ana, a aia paha nā hopena ʻaoʻao o kēia lāʻau i nā kāne a me nā wahine.

ʻO kekahi mea kāohi 5-alpha reductase i kapa ʻia dutasteride (Avodart) ke nānā ʻia nei ma ke ʻano he lapaʻau kūpono no MPB. Aia ia i kēia manawa ma ka mākeke no ka mālama ʻana i kahi prostate hoʻonui ʻia.

ʻO nā koho lapaʻau ʻē aʻe e pili ʻole i ka testosterone a i ʻole ka DHT:

• minoxidil (Rogaine)
• ketoconazole
• lapaau kukuna
• hoʻoiho lauoho lauoho ʻoki kino