Sclerosing cholangitis: he aha ia, nā ʻōuli a me nā lāʻau

Anter

• Nā ʻōuli o sclerosing cholangitis
• Nā kumu nui
• Pehea e hana ʻia ai ke kuhi
• Iapaau ana no sclerosing cholangitis

ʻO Sclerosing cholangitis kahi maʻi maʻamau i ʻike pinepine ʻia e nā kāne e pili ana i ke komo ʻana o ke akepaʻa ma muli o ka mumū a me ka fibrosis i hoʻokumu ʻia e ka hoʻopili ʻana o nā kahawai e hele ai ka bile, kahi waiwai nui no ke kaʻina digestive, hiki ke alakaʻi i kekahi mau hihia i ka ke ʻano o kekahi mau ʻōuli, e like me ka luhi nui, ʻili melemele a me nā maka a me ka nāwaliwali o nā mākala.

ʻAʻole maopopo loa nā kumu o ka cholangitis, akā manaʻo ʻia he pili paha ia i nā kumu autoimmune e hiki ai ke alakaʻi i ka ulu holomua o nā aʻa aʻa. Wahi a ke kumu, hiki ke hoʻohālikelike ʻia ka sclerose cholangitis i ʻelua mau ʻano nui:

• ʻO cholangitis sclerosing mua, kahi i hoʻomaka ai ka loli i nā aʻa o ka bile;
• ʻO cholangitis sclerosing lua, kahi o ka loli kahi hopena o kahi loli hou, e like me ka tumo a i ʻole trauma i ka pūnaewele, no ka laʻana.

He mea nui e ʻike ʻia ke kumu o ka cholangitis i hiki ai ke hōʻike ʻia ka lāʻau kūpono kūpono loa a no laila, paipai ʻia e kūkākūkā me ka loio maʻamau a i ʻole he hepatologist i mea e hōʻike ai i nā hoʻokolohua kiʻi a me nā keʻena hoʻokolohua e ʻae ai i ka ʻike ʻana.

Nā ʻōuli o sclerosing cholangitis

ʻO ka hapa nui o nā maʻi cholangitis ʻaʻole i alakaʻi i ke ʻano o nā hōʻailona a i ʻole nā ​​hōʻailona, ​​a ʻike wale ʻia kēia hoʻololi i nā hoʻokolohua kiʻi. Eia nō naʻe, ʻike paha kekahi poʻe i nā ʻōuli, keu hoʻi i ka sclerose cholangitis, kahi e loaʻa mau ai ka bile i ke ake. No laila, ʻo nā ʻōuli nui e hōʻike ana i ka cholangitis:

• Luhi nui loa;
• Kino ʻino;
• ʻIli melemele a me nā maka;
• Loaʻa paha ke anuanu a me ka ʻeha o ka ʻōpū;
• Nāwaliwali o ka ʻiʻo;
• Kaumaha emi;
• Hoʻonui ākea;
• Hoʻonui ākea;
• Ke kū mai o xanthomas, he mau leona ma ka ʻili i hana ʻia i nā momona;
• Kāwili.

I kekahi mau hihia, loaʻa nō kekahi diarrhea, ʻeha o ka ʻōpū a me ke kū ʻana o ke koko a i ʻole nā ​​mucus i ka pahu. I ke alo o kēia mau ʻōuli, keu hoʻi inā hoʻi hou a hoʻomau paha ia, he mea nui e nīnau aku i ka loio maʻamau a i ʻole he hepatologist i hiki ke hoʻokō ʻia nā hoʻokolohua a hoʻomaka ʻia ka lapaʻau kūpono.

Nā kumu nui

ʻAʻole i hoʻokumu maikaʻi ʻia nā kumu o ka sclerose cholangitis, akā manaʻo ʻia he kumu ia no nā loli autoimmune a i ʻole pili i nā kumu aʻa a i ʻole nā ​​maʻi a nā mea hoʻomaʻi paha.

Hoʻohui ʻia, manaʻo ʻia ʻo ka sclerosing cholangitis e pili ana i ka ulcerative colitis, kahi i ʻoi aku ka makaʻu o ka poʻe me kēia ʻano maʻi ʻōpū no ka hoʻomōhala ʻana i ka cholangitis.

Pehea e hana ʻia ai ke kuhi

ʻO ka ʻike ʻana o sclerose cholangitis e hana ʻia e ka mea hana maʻamau a i ʻole he kauka lāʻau paha ma o nā hoʻokolohua a me nā hoʻokolohua kiʻi. ʻO ka maʻamau, hana ʻia ka ʻike mua ma o nā hopena o nā hoʻokolohua e loiloi i ka hana o ke ake, me nā loli i ka nui o nā enzymes o ke ake, e like me TGO a me TGP, me ka hoʻonui ʻana i ka alkaline phosphatase a me gamma-GT. I kekahi mau hihia, noi paha ke kauka i ka hana o nā protein electrophoresis, kahi e ʻike ʻia ai ka hoʻonui ʻia o nā gamma globulins, ʻo IgG ka nui.

E hōʻoia i ke kuhi, hiki i ke kauka ke noi i kahi biopsy ate a me cholangiography, kahi hōʻike diagnostic e manaʻo ana e loiloi i nā aʻa aʻa a nānā i ke ala mai ka aʻa mai ke ake a i ka duodenum, hiki ke ʻike i nā loli. E hoʻomaopopo pehea e hana ai i ka cholangiography.

Iapaau ana no sclerosing cholangitis

Hana ʻia no ka sclerosing cholangitis e like me ka paʻakikī o ka cholangitis a me ka pahuhopu e hāpai i ka hōʻailona hōʻailona a pale i nā pilikia. He mea nui ka hoʻomaka ʻana o ka lapaʻau ma hope koke iho o ka ʻike e pale ai i ka holomua o ka maʻi a hopena i nā pilikia e like me ka cirrhosis o ke ake, ka hanu kiʻekiʻe a me ka holo pono ʻole o ke ake.

No laila, ʻo ka hoʻohana ʻana i kahi lāʻau i loaʻa ka ursodeoxycholic acid, i ʻike ʻia ʻo Ursacol, hiki ke hōʻike ʻia e ke kauka, me ka hoʻohui ʻana i ka lāʻau endoscopic i mea e hōʻemi ai i ke kēkelē o ka ālai a makemake i ka hele ʻana o ka bile. I nā hihia ʻoi loa o ka cholangitis, kahi i hoʻomaikaʻi ʻole ʻia ai nā ʻōuli me ka hoʻohana ʻana i nā lāʻau, a i ʻole ke hoʻi hou ʻia nā ʻōuli, e ʻōlelo paha ke kauka e hana i kahi transplant ake.