Angiokeratoma

Anter

• He aha nā ʻano ʻokoʻa?
• He aha nā hōʻailona?
• He aha ke kumu o ka angiokeratoma?
• Pehea e ʻike ʻia ai ka angiokeratoma?
• Pehea e mālama ʻia ai?
• He aha ka manaʻo no ka poʻe me angiokeratoma?

He aha ka angiokeratoma?

ʻO Angiokeratoma kahi ʻano i hōʻike ʻia nā wahi ʻeleʻele a me nā ʻeleʻele i ka ʻili. Hiki iā lākou ke hōʻike ma kahi o kou kino. Kū kēia mau liona ke kīloi nā kīʻaha koko liʻiliʻi i kapa ʻia nā capillaries, a ākea paha, kokoke i ka ʻili o kou ʻili.

Hiki paha i ka Angiokeratomas ke kolohe i ka hoʻopā. Hōʻike pinepine ʻia lākou i nā huhui i ka ʻili a puni ka:

• peni
• scrotum
• puʻupuʻu
• labia majora

Hiki ke kuhihewa lākou no ka ʻōpala, ka maʻi ʻaʻai ʻili, a i ʻole kahi ʻano e like me nā warts genital a i ʻole herpes. ʻO ka hapanui o ka manawa, ʻaʻohe mea makehewa angiokeratomas a ʻaʻole pono e mālama.

ʻO Angiokeratomas i kekahi manawa ke lilo i hōʻailona o kahi ʻano paʻa, e like me ka maʻi genetika ʻike ʻia ʻo Fabry maʻi (FD). Pono ʻoe e ʻike i ke kauka no ka mālama ʻana e pale ai i nā pilikia.

He aha nā ʻano ʻokoʻa?

Nā ʻano o angiokeratoma e:

• Angiokeratoma mehameha. Hōʻike pinepine ʻia kēia mau mea. ʻIke pinepine lākou i kou mau lima a me kou mau wāwae. ʻAʻole lākou he mea hōʻino.
• Angiokeratoma o Fordyce. Hōʻike kēia mau mea i ka ʻili o ka scrotum a i ʻole vulva. ʻIke pinepine ʻia lākou ma ka scrotum i nā hui nui. Hiki i kēia ʻano ke hoʻomohala ma ka puʻu o nā wahine hāpai. ʻAʻole lākou he mea hōʻino, akā maʻalahi lākou i ke kahe inā ʻōpala lākou.
• Angiokeratoma o Mibelli. ʻO kēia nā hopena mai nā kīʻaha koko dilated i kokoke loa i ka epidermis, a i ʻole ka papa luna o kou ʻili. ʻAʻole lākou ʻino. Mālama kēia ʻano i ka mānoanoa a paʻakikī hoʻi i ka manawa i kahi kaʻina i kapa ʻia ʻo hyperkeratosis.
• Angiokeratoma circumscriptum. He ʻano rarer kēia i hōʻike ʻia i nā huhui i kou mau wāwae a i ʻole ke kino. Hiki iā ʻoe ke hānau ʻia me kēia ʻano. Mālama ʻo ia i ka morph i ka helehelena i ka hala ʻana o ka manawa, lilo i pouli a i ʻole lawe i nā ʻano like ʻole.
• Angiokeratoma corporis diffusum. ʻO kēia ʻano kahi hōʻailona o FD. Hiki iā ia ke hana me nā maʻi lysosomal ʻē aʻe, kahi e hoʻopili ai i ka holo ʻana o nā pūnaewele. Kākaʻikahi kēia ʻano a loaʻa nā hōʻailona e ʻike ʻia, e like me ka puhi ʻana i nā lima a me nā wāwae a i ʻole nā ​​pilikia ʻike. ʻO kēia mau angiokeratomas e maʻa mau a puni ke kino haʻahaʻa. Hiki iā lākou ke hōʻike ma kahi o ka lalo o kou kino i kou mau ʻūhā kiʻekiʻe.

He aha nā hōʻailona?

Hiki ke ʻokoʻa ke kinona, ka nui, a me ke kala. Hiki iā ʻoe ke loaʻa nā hōʻailona hou inā loaʻa iā ʻoe kahi ʻano pili, e like me FD.

Ma ka laulā, hōʻike ʻo angiokeratomas i kēia mau ʻōuli:

• ʻike ʻia ma ke ʻano he mau puʻupuʻu liʻiliʻi a waena paha mai 1 millimeter (mm) a 5 mm a i ʻole i nā ʻano jagged, e like me ka wart.
• loaʻa ke ʻano like me ka Dome
• mānoanoa a paʻakikī paha i ka ʻili
• hōʻike hoʻokahi a i ʻole i nā huhui o kekahi mau a kokoke i hoʻokahi haneli
• ʻeleʻele-ʻeleʻele, me ʻulaʻula, polū, poni, a ʻeleʻele

Angiokeratomas i hele wale mai nei e ʻulaʻula i ke kala. ʻO nā kiko ma kou ʻili no kekahi manawa ʻoi aku ka pouli.

Hiki ke ʻike ʻia ʻo Angiokeratomas ma ka scrotum me ka ʻulaʻula ma kahi ākea o ka scrotum. ʻO ke Angiokeratomas ma ka scrotum a i ʻole vulva paha e kahe maʻalahi ke kahe ʻia ma mua o nā mea ma nā ʻāpana ʻē aʻe o kou kino.

Inā loaʻa ʻoe i kahi ʻano e like me FD e hōʻike nei i angiokeratomas, kahi mau hōʻailona ʻē aʻe āu e ʻike ai e pili pū ana:

• akoparesthesias, a i ʻole ʻeha ma kou mau lima a me kou mau wāwae
• tinnitus, a i ʻole kani kani i kou mau pepeiao
• opacity, a i ʻole cloudiness i kāu ʻike
• hypohidrosis, a i ʻole hiki ʻole ke hou pono i ka hou
• ʻeha ma kou ʻōpū a me kou ʻōpū
• ke manaʻo nei i ka makemake e hoʻowahāwahā ma hope o ka ʻai

He aha ke kumu o ka angiokeratoma?

Hoʻokumu ʻia ʻo Angiokeratomas e ka dilation o nā kīʻaha koko kokoke i ka ʻili o ka ʻili. Hoʻokumu ʻia nā angiokeratomas mehameha e nā ʻeha i hana ʻia ma mua ma kahi i kū ai lākou.

Ua hala ʻo FD i loko o nā ʻohana, a hiki ke hana i angiokeratomas. Ma kahi o 1 i kēlā me kēia 40,000 a 60,000 mau kāne i loaʻa ka FD, e like me ka U.S. Genetery Library of Medicine's genetics department.

Ma mua o kā lākou hui pū ʻana me FD a me nā kūlana lysosomal ʻē aʻe, ʻaʻole maopopo mau ke kumu o nā angiokeratomas. ʻO nā kumu i hiki ke hoʻopili ʻia:

• hypertension, a i ʻole ke koko kiʻekiʻe ma nā veins kokoke i ka ʻili
• ke loaʻa i kahi kūlana e hoʻopili i nā moku koko kūloko, e like me ka inguinal hernia, hemorrhoids, a i ʻole varicocele (ke hoʻonui ʻia nā uaua i ka scrotum)

Pehea e ʻike ʻia ai ka angiokeratoma?

ʻAʻohe pono ʻole ʻo Angiokeratomas. ʻAʻole pono ʻoe e ʻike i ke kauka no kahi hōʻailona.

Akā inā ʻoe e ʻike i nā ʻōuli ʻē aʻe, e like me ka kahe pinepine ʻana o ke koko a i ʻole nā ​​hōʻailona o FD, e ʻike koke i kāu kauka no kahi hōʻailona a me kahi lāʻau. Hiki paha iā ʻoe ke ʻike i kāu kauka inā manaʻo ʻoe he maʻi maʻi kahi maʻi e like me ka angiokeratoma.

E lawe kāu kauka i kahi laʻana kikoʻī o kahi angiokeratoma e kuhikuhi iā ia. ʻIke ʻia kēia ma ke ʻano he biopsy. I kēia kaʻina hana, hiki i kāu kauka ke excise, a ʻokiʻoki paha, i kahi angiokeratoma mai kou ʻili i mea e lawe aku ai ia no ke kālailai. Pili paha kēia i kāu kauka e hoʻohana ana i kahi scalpel e wehe i ka angiokeratoma mai kona kumu ma lalo o ka ʻili.

Hiki paha i kāu kauka ke koi aku i kahi hōʻike gene GLA e ʻike inā he FD kāu. Hoʻokumu ʻia ʻo FD e nā mutation i kēia gen.

Pehea e mālama ʻia ai?

ʻAʻole pono e mālama ʻia ʻo Angiokeratomas inā ʻaʻole ʻoe e ʻike i kahi ʻoluʻolu a i ʻole ʻeha. Makemake paha ʻoe e hemo iā lākou inā kahe pinepine lākou a i ʻole no nā kumu cosmetic. I kēia hihia, loaʻa nā koho lapaʻau he nui:

• ʻO ka uila a me ka curettage (ED&C). Hoʻomaʻomaʻo kāu kauka i ka wahi a puni ka angiokeratomas me kahi anesthesia kūloko, a laila hoʻohana i ka cautery uila a me nā pono hana e ʻānai i nā kiko a wehe i nā mea.
• Lawe ka laser. Hoʻohana kāu kauka i nā lasers, e like me ka laser make pulsed, e luku ai i nā kīʻaha koko i hoʻonui ʻia i angiokeratomas.
• ʻO Cryotherapy. Hoʻopaʻahau kāu kauka i ka angiokeratomas a me nā a puni e lawe iā lākou.

Pākuʻi ʻia paha no FD nā lāʻau, e like me:

• ʻO Agalsidase beta (Fabrazyme). E loaʻa iā ʻoe nā werana Fabrazyme maʻamau e kōkua i kou kino i ka haki ʻana i nā momona o ke keu keu i kūkulu ʻia ma muli o ka nalowale ʻana o kahi ʻenemema i hoʻokumu ʻia e ka hoʻololi ʻana o ka gene GLA.
• Neurontin (Gabapentin) a i ʻole carbamazepine (Tegretol). Hiki i kēia mau lāʻau lapaʻau ke mālama i ka ʻeha o ka lima a me ka wāwae.

Hiki i kāu kauka ke koi aku iā ʻoe e ʻike i nā loea no ka puʻuwai, nā puʻuwai, a i ʻole nā ​​ʻōnaehana ʻōnaehana o FD pū kekahi.

He aha ka manaʻo no ka poʻe me angiokeratoma?

ʻAʻole maʻamau ka Angiokeratomas i ka hopohopo. E ʻike i kāu kauka inā ʻike ʻoe i ke kahe ʻana o ke kahe a i ʻole ka ʻeha i ka angiokeratomas, a i ʻole inā kuhi ʻoe aia kekahi kumu kumu e hōʻoluʻolu ai ʻoe a i ʻole ʻeha.