Aimovig (erenumab-aooe)

Anter

• He aha ʻo Aimovig?
• ʻO kahi ʻano lāʻau hou
• ʻO Generic Aimovig
• Nā hopena ʻaoʻao Aimovig
• Nā hopena ʻaoʻao hou aʻe
• Nā hopena hopena koʻikoʻi
• Ka hopena hoʻowali
• Kaumaha emi / loaʻa waiwai
• Nā hopena wā lōʻihi
• Konipōpō
• Lilo ka lauoho
• Nusea
• Ka luhi
• Pohā
• ʻO Insomnia
• ʻEha ʻeha
• Kāwili
• ʻO ke kumukūʻai Aimovig
• Kōkua kālā
• Hoʻohana ʻo Aimovig
• ʻO Aimovig no ka ulu poʻo o ka migraine
• Hoʻohana i ʻae ʻole ʻia
• ʻ .kuhi Aimovig
• Nā ʻano a me nā ikaika
• Nā hana no migraine
• He aha inā e haʻo wau i kahi lāʻau?
• Pono wau e hoʻohana i kēia lāʻau lōʻihi?
• Nā koho ʻē aʻe iā Aimovig
• Nā mea kūʻē CGRP
• Aimovig vs. nā lāʻau ʻē aʻe
• Aimovig vs. Ajovy
• Aimovig vs. Botox
• ʻO Aimovig vs. Emgality
• Aimovig vs. Topamax
• ʻAimovig a me ka waiʻona
• Nā pilina Aimovig
• Pehea e hoʻohua ʻia ai ʻo Aimovig
• Nā ʻōkuhi pehea e lawe ai iā Aimovig
• Pehea e hoʻopili ai
• Manawa
• Lawe iā Aimovig me ka meaʻai
• Waihona
• Pehea e hana ai ʻo Aimovig
• Pehea ka lōʻihi o ka hana?
• ʻO Aimovig a me ka hāpai keiki
• ʻO Aimovig a me ka hānai ʻana i ka waiū
• Nā nīnau e pili ana iā Aimovig
• ʻO ke kū ʻana iā Aimovig ke kumu o ka haʻalele ʻana?
• He biologic ʻo ʻAimovig?
• Hiki iā ʻoe ke hoʻohana iā Aimovig e mālama i ka migraine?
• Hoʻoponopono ʻo Aimovig i ka migraine?
• Pehea ʻokoʻa ʻo Aimovig mai nā lāʻau migraine ʻē aʻe?
• Inā lawe au iā Aimovig, hiki iaʻu ke hōʻoki i ka lawe ʻana i kaʻu mau lāʻau pale ʻē aʻe?
• Hoʻopiʻi over Aimovig
• Nā hōʻailona overdose
• He aha e hana ai inā he overdose
• Nā ʻōlelo aʻoaʻo Aimovig
• Pau ʻo Aimovig a me kahi waiho
• ʻO ka ʻike ʻoihana no Aimovig
• Mekanism o ka hana
• Pharmacokinetics a me ka metabolism
• Nā Kūʻai Kūʻai
• Waihona

He aha ʻo Aimovig?

ʻO Aimovig kahi lāʻau lapaʻau inoa inoa inoa inoa e hoʻohana ʻia e pale i ka ulu ʻana o ka migraine i nā mākua. Hele mai ia i kahi peni autoinjector prefilled. Hoʻohana ʻoe i ka autoinjector e hāʻawi iā ʻoe iho i ka injection i ka home hoʻokahi i kēlā me kēia mahina. Hiki ke kuhikuhi ʻia ʻo Aimovig i hoʻokahi o nā mahele ʻelua: 70 mg i kēlā me kēia mahina a i ʻole 140 mg i kēlā me kēia mahina.

Aia i loko o Aimovig ka lāʻau lapaʻau erenumab. ʻO Erenumab kahi antibody monoclonal, kahi ʻano lāʻau i hoʻomohala ʻia i kahi lab. ʻO nā kinikini monoclonal nā lāʻau i hana ʻia mai nā pūnaewele ʻōnaehana pale. Hana lākou ma ka pale ʻana i ka hana o kekahi mau protein i kou kino.

Hiki ke hoʻohana ʻia ʻo Aimovig e pale aku i ka migraine episodic a me nā poʻo hina migraine mau. Paipai ka American Headache Society iā Aimovig no ka poʻe i:

• ʻaʻole hiki ke hōʻemi i kā lākou helu o ka ulu ʻana o ka migraine o ka mahina i lawa me nā lāʻau ʻē aʻe
• ʻaʻole hiki ke lawe i nā lāʻau migraine ʻē aʻe ma muli o nā hopena a i ʻole nā ​​launa ʻana o ka lāʻau

Ua hōʻike ʻia ka maikaʻi o Aimovig i nā noiʻi maʻi ʻana. No ka poʻe me ka migraine episodic, ma waena o 40 pākēneka a me 50 pākēneka o ka poʻe i lawe iā Aimovig no ʻeono mau mahina e ʻoki i kā lākou helu o nā lā migraine ma ka liʻiliʻi o ka hapalua. A no ka poʻe me ka migraine mau, ma kahi o 40 pākēneka o ka poʻe i lawe iā Aimovig e ʻoki i kā lākou helu o nā lā migraine e ka hapalua a ʻoi paha.

ʻO kahi ʻano lāʻau hou

ʻO Aimovig kahi ʻāpana o kahi papa hou o nā lāʻau i kapa ʻia he antagonists peptide (CGRP) pili pū kekahi me ka calanite. Ua hoʻomohala ʻia kēia ʻano lāʻau no ka pale ʻana i ka maʻi migraine.

Ua ʻae ʻo Aimovig i ka ʻAi a me nā lāʻau lapaʻau (FDA) i ka Mei 2018. ʻO ia ka lāʻau mua i ʻae ʻia i ka papa antagonist CGRP o nā lāʻau.

Ua ʻae ʻia ʻelua mau lāʻau ʻē aʻe i kēia papa o nā lāʻau i hope o Aimovig: Emgality (galcanezumab) a me Ajovy (fremanezumab). ʻO kahi lāʻau ʻehā, i kapa ʻia ʻo eptinezumab, ke hoʻopaʻa ʻia nei i nā hoʻokolohua hoʻokolohua.

ʻO Generic Aimovig

ʻAʻole loaʻa ʻo Aimovig i kahi ʻano laulā. Hele mai ia ma ke ʻano he lāʻau lapaʻau inoa.

Aia i loko o Aimovig ka lāʻau lapaʻau erenumab, a ʻo ia hoʻi ʻo erenumab-aooe. Hoʻohui ʻia ka hopena "-aooe" i kekahi manawa e hōʻike i ka ʻokoʻa o ka lāʻau mai nā lāʻau like e hiki ke hana ʻia i ka wā e hiki mai ana. ʻO nā lāʻau lāʻau monoclonal ʻē aʻe i loaʻa nā ʻano inoa e like me kēia.

Nā hopena ʻaoʻao Aimovig

Hiki iā Aimovig ke hana i nā hopena ʻoluʻolu a koʻikoʻi paha. Aia i ka papa inoa aʻe kekahi o nā hopena ʻaoʻao nui i hiki ke hana ʻia i ka lawe ʻana iā Aimovig. ʻAʻole pili kēia papa inoa i nā hopena ʻē aʻe āpau.

No ka ʻike hou aku e pili ana i nā hopena ʻē aʻe o Aimovig, a i ʻole nā ​​ʻōlelo aʻoaʻo e pili ana i ka hopena o ka hopena pilikia, e kamaʻilio me kāu kauka a kauka paha.

Kaha: Mālama ka Food and Drug Administration (FDA) i nā hopena o nā lāʻau a lākou i ʻae ai. Inā makemake ʻoe e hōʻike i ka FDA i kahi hopena i loaʻa iā ʻoe me Aimovig, hiki iā ʻoe ke hana pēlā ma o MedWatch.

Nā hopena ʻaoʻao hou aʻe

Hiki i nā hopena ʻaoʻao maʻamau o Aimovig ke hoʻopili pū i:

• nā ʻaoʻao pūnaewele injection (ʻulaʻula, ʻili ʻili, ʻeha)
• kōpaʻa
• ʻūpē mākala
• ʻūpē mākala

E hala paha ka hapa nui o kēia mau hopena ʻaoʻao ma hope o kekahi mau lā a i ʻole ʻelua mau pule. Kāhea i kāu kauka a kauka paha inā ʻoi aku ka nui o nā hopena ʻē aʻe a i ʻole nā ​​hopena i hele ʻole.

Nā hopena hopena koʻikoʻi

Hiki ke hana i nā hopena koʻikoʻi mai Aimovig, akā ʻaʻole maʻamau. ʻO ka hopena koʻikoʻi koʻikoʻi o Aimovig kahi hopena maʻi maʻi. E nānā ma lalo no nā kikoʻī.

Ka hopena hoʻowali

Loaʻa i kekahi poʻe kahi maʻi maʻi ma hope o ka lawe ʻana iā Aimovig. Hiki ke loaʻa kēia ʻano ʻano me ka hapa nui o nā lāʻau. ʻO nā ʻōuli o kahi hopena maʻi ʻaʻano haʻahaʻa e hoʻopili pū paha:

• loaʻa ka hū i kou ʻili
• ʻalalā
• e hoʻomake ʻia (me ka mehana a me ka ʻula i kou ʻili)

Kākaʻikahi, hiki ke hana i nā hopena maʻi ʻoi loa. Nā hōʻailona o kahi hopena maʻi ʻaʻai nui e komo pū paha:

• ka pehu ʻana ma lalo o kou ʻili (maʻamau i kou mau lihilihi, lehelehe, lima, a mau wāwae paha)
• pōkole o ka hanu a i ʻole pilikia i ka hanu ʻana
• ka pehu ʻana i kou alelo, waha, a ʻāʻā paha

Kāhea koke i kāu kauka inā manaʻo ʻoe ke loaʻa nei ʻoe i kahi maʻi maʻi ʻino iā ʻAimovig. Kāhea iā 911 inā manaʻo kou mau hōʻailona i ka hoʻoweliweli ola a i ʻole inā loaʻa ʻoe i kahi pilikia olakino.

Kaumaha emi / loaʻa waiwai

ʻAʻole i hōʻike ʻia ke kaupaona a me ka loaʻa ʻana o ke kaupaona i nā noiʻi maʻi o Aimovig. Eia nō naʻe, ʻike paha kekahi poʻe i nā loli i ko lākou kaumaha i ka wā o ka hoʻomaʻamaʻa ʻana iā Aimovig. Ma muli paha o ka migraine ponoʻī ma mua o Aimovig.

ʻAʻole pōloli kekahi poʻe ma mua, i ka wā, a ma hope paha o ka ulu ʻana o ka migraine. Inā lawa kēia pinepine, hiki iā ia ke alakaʻi i ka hōʻemi kaumaha i makemake ʻole ʻia. Inā nele ʻoe i kou makemake inā loaʻa ʻoe i ka maʻi migraine, e hana pū me kāu kauka e hoʻomohala i kahi papa papaʻai e hōʻoia i ka loaʻa ʻana o nā meaʻai āpau āu e pono ai.

Ma ka hopena ʻē aʻe o ka pae, loaʻa ka loaʻa kaupaona a momona paha i nā poʻe me ka migraine. A ua hōʻike ʻia nā noiʻi hoʻokolohua he mea weliweli paha ka momona no ka ʻeha ʻana o ka ulu o ka migraine a ʻoi aku paha ka nui o ka maʻi migraine pinepine.

Inā ʻoe e hopohopo e pili ana i ka hopena o kou kaumaha i kāu maʻi migraine, e kamaʻilio me kāu kauka e pili ana i nā ala e mālama ai i kou kaumaha.

Nā hopena wā lōʻihi

ʻO ʻAimovig kahi lāʻau i ʻāpono hou ʻia i kahi papa hou o nā lāʻau. A ʻo kahi hopena, aia kahi noiʻi noiʻi lōʻihi loa e loaʻa ana i ka palekana o Aimovig, a ʻaʻole ʻike iki ʻia e pili ana i nā hopena lōʻihi.

I hoʻokahi loiloi palekana lōʻihi i hala ma kahi o ʻekolu mau makahiki, ʻo nā hopena ʻaoʻao loa i hōʻike ʻia me Aimovig:

• ʻeha kua
• ʻo nā maʻi hanu luna (e like me ke anuanu maʻamau a i ʻole ka maʻi sinus)
• nā ʻōuli like flu

Inā loaʻa kēia mau hopena ʻaoʻao a koʻikoʻi lākou a mai hele aku paha, e kamaʻilio me kāu kauka.

Konipōpō

Ua paʻa ka paʻa paʻa a hiki i ka 3 pākēneka o ka poʻe i lawe iā Aimovig i loko o nā noiʻi maʻi.

Ma muli paha o ka hopena ʻana o Aimovig i ka peptide pili i ka ʻaoʻao pili kalona (CGRP) i kou kino. ʻO ka CGRP kahi protein i hiki ke loaʻa i loko o nā ʻōpū a hana nui i ka neʻe ʻana o ka ʻōpū. Pale ʻo Aimovig i ka hana a CGRP, a hiki i kēia hana ke pale i nā neʻe ʻana o ka ʻōpū maʻamau.

Inā ʻike ʻoe i ka constipation i ka wā o ka mālama ʻana me Aimovig, e kamaʻilio me kāu kauka a mea kauka paha e pili ana i nā lāʻau i hiki ke kōkua i ka hoʻomaha ʻana iā ia.

Lilo ka lauoho

ʻAʻole ka hopena o ka lauoho i ka hopena i hoʻopili ʻia me Aimovig. Inā ʻike ʻoe e lilo ana kou lauoho, e kamaʻilio me kāu kauka e pili ana i nā kumu a me nā hana kūpono.

Nusea

ʻAʻole ʻo Nusea kahi hopena ʻaoʻao i hōʻike ʻia me ka hoʻohana Aimovig. Eia nō naʻe, manaʻo nui ka poʻe me ka migraine i ka wā o ka maʻi migraine.

Inā huhū ʻoe i ka wā o ka huhū o ka migraine, kōkua paha ia e noho i kahi keʻena pouli a me ka mālie, a i ʻole e hele i waho no ka ea hou. Hiki iā ʻoe ke nīnau i kāu kauka a kauka paha e pili ana i nā lāʻau e hiki ke kōkua i ka pale ʻana a mālama ʻana paha i ka nausea.

Ka luhi

ʻO ka luhi (nele o ka ikehu) ʻaʻole ia he hopena ʻaoʻao i hoʻopili ʻia me Aimovig. Akā ʻo ka luhi ka manaʻo luhi kahi hōʻailona maʻamau o ka migraine i ʻike ʻia e ka poʻe he nui ma mua, i ka wā, a ma hope paha o ka loaʻa ʻana o ka maʻi migraine.

Ua hōʻike ʻia kahi noiʻi hoʻokolohua ua ʻike ʻia ka luhi i ka poʻe me ka migraine i ʻoi loa ka ʻeha o ke poʻo.

Inā pilikia ʻoe i ka luhi, e kamaʻilio me kāu kauka e pili ana i nā ala e hoʻomaikaʻi ai i kāu pae ikehu.

Pohā

ʻAʻole kahi hopena o ka maʻi diarrhea i hōʻike ʻia me ka hoʻohana ʻana o Aimovig. Eia nō naʻe, he hōʻailona laha ʻole ia o ka migraine. Aia paha kahi loulou ma waena o migraine a me nā maʻi ʻōpū a me nā maʻi gastrointestinal ʻē aʻe.

Inā loaʻa ʻoe i ka maʻi palahā ʻoi aku ka lōʻihi ma mua o kekahi mau lā, e kamaʻilio me kāu kauka.

ʻO Insomnia

ʻO ka hiamoe (pilikia ka hiamoe ʻana) ʻaʻole ia he hopena ʻaoʻao i loaʻa i nā noiʻi maʻi o Aimovig. Eia nō naʻe, ua ʻike ʻia kahi noiʻi hoʻokolohua i ka poʻe me ka migraine i loaʻa ʻole ka hiamoe e loaʻa pinepine i ka ʻeha o ka migraine pinepine. ʻO ka ʻoiaʻiʻo, ʻaʻole ka hiamoe e hoʻonāukiuki ai i ka ulu o ka migraine a hoʻonui i ka makaʻu o ka ulu ʻana o ka migraine mau.

Inā loaʻa ʻoe i ka hiamoe a noʻonoʻo paha e pili ana i kou huhū migraine, e kamaʻilio me kāu kauka e pili ana i nā ala e loaʻa ai ka hiamoe maikaʻi.

ʻEha ʻeha

I nā noiʻi hoʻokolohua, ʻaʻole i ʻike ka poʻe i loaʻa iā Aimovig i ka ʻeha o ka mākala maʻamau. Loaʻa i kekahi i nā ʻūlū a me nā spasms, a i kahi loiloi palekana wā lōʻihi, ua ʻike ka poʻe e lawe nei iā Aimovig i ka ʻehaʻeha.

Inā loaʻa iā ʻoe ka ʻehaʻeha i ka lawe ʻana iā Aimovig, no nā kumu ʻē aʻe paha ia. ʻO kahi laʻana, hiki i ka ʻehaʻeha i ka ʻāʻī ke lilo i hōʻailona o migraine no kekahi poʻe. Eia kekahi, ʻo nā hopena o ka pūnaewele hoʻoheheʻe, e like me ka ʻeha ma nā wahi e puni ana i ka ʻinikua, manaʻo paha e like me ka ʻeha ʻeha. Pono e hele kēia ʻano ʻeha i loko o kekahi mau lā o ke kuikui.

Inā loaʻa iā ʻoe ka ʻeha o ka ʻeha e hele ʻole a i ʻole ke hoʻololi ʻana i kou ʻano o ke ola, e kamaʻilio me kāu kauka e pili ana i nā koho hōʻoluʻolu ʻeha.

Kāwili

ʻAʻole ka ʻino nui ka hopena i ʻike ʻia i loko o nā noiʻi maʻi o Aimovig. Eia nō naʻe, hōʻike pinepine ʻia ka ʻili ʻili ma kahi e kiki ʻia ai ʻo Aimovig.

Pono e hele ka ʻili ʻili ma kahi o ka pūnaewele injection i loko o kekahi mau lā. Inā loaʻa ka makaʻu ʻaʻole e hele, a inā nui ka ʻili, e kamaʻilio me kāu kauka.

ʻO ke kumukūʻai Aimovig

E like me nā lāʻau āpau, hiki i nā kumukūʻai no Aimovig ke loli.

E hilinaʻi kāu kumukūʻai maoli i kāu uhi ʻinikua, kou wahi, a me ka hale kūʻai lāʻau āu e hoʻohana ai.

Kōkua kālā

Inā makemake ʻoe i kākoʻo kālā e uku no Aimovig, loaʻa ke kōkua.

Hāʻawi ʻo Amgen lāua ʻo Novartis, nā mea hana o Aimovig, i kahi papahana Aimovig Ally Access Card e hiki ke kōkua iā ʻoe e uku i ka uku no kēlā me kēia hoʻopiha hou. No ka ʻike hou aku a e ʻike inā ua kūpono ʻoe, e kāhea iā 833-246-6844 a i ʻole kipa i ka pūnaewele pūnaewele.

Hoʻohana ʻo Aimovig

Ua ʻae ka Food and Drug Administration (FDA) i nā lāʻau i kuhikuhi ʻia e like me Aimovig e mālama a pale aku paha i kekahi mau ʻano.

ʻO Aimovig no ka ulu poʻo o ka migraine

Ua ʻae ʻia ʻo Aimovig e ka FDA no ka pale ʻana i ka ʻeha o ka migraine i nā mākua. ʻO kēia mau maʻi poʻo nui ka hōʻailona maʻamau o ka migraine, kahi ʻano neurological.

Hiki i nā ʻōuli ʻē aʻe ke hana me ka maʻi migraine, e like me:

• nausea
• ka luaʻi
• ʻike i ke kukui a me ke kani
• pilikia i ka ʻōlelo ʻana

Hiki ke hoʻokaʻawale ʻia ʻo Migraine ma ke ʻano he episodic a i ʻole mau, e like me ka International Headache Society. Ua ʻae ʻia ʻo Aimovig e pale aku i ka migraine episodic a me nā poʻo hina migraine maʻi mau. ʻO nā ʻokoʻa ma waena o kēia ʻano migraine:

• ʻO ka migraine episodic ke kumu o ka liʻiliʻi ma mua o 15 headache a i ʻole migraine mau lā i kēlā me kēia mahina
• Hoʻokumu ka migraine mau i 15 a ʻoi aʻe mau lā ʻeha i kēlā me kēia mahina ma kahi o ʻekolu mau mahina, me ka liʻiliʻi o ʻewalu mau lā he mau lā migraine.

Hoʻohana i ʻae ʻole ʻia

Hiki ke hoʻohana ʻia ʻo Aimovig i ka lepili hōʻailona no nā kūlana ʻē aʻe. ʻO ka hoʻohana inoa inoa ʻole ʻana ke hāʻawi ʻia kahi lāʻau i ʻae ʻia e mālama i hoʻokahi kūlana e mālama ai i kahi ʻano ʻokoʻa.

ʻO Aimovig no nā huhū puʻupuʻu

ʻAʻole ʻae ʻia ʻo Aimovig e ʻākoʻo iā FDA e pale i nā hōʻeha puʻupuʻu puʻupuʻu, akā hiki ke hoʻohana ʻia i ka inoa lepili no kēia kumu. ʻAʻole ʻike ʻia i kēia manawa inā maikaʻi ʻo Aimovig i ka pale ʻana i nā huhū pūpū.

ʻO nā poʻo hina he ʻeha poʻo ʻeha e kū i nā huhui (he nui nā poʻo poʻo i kahi manawa pōkole). Hiki iā lākou ke lilo i episodic a i ʻole mau. ʻOi aku ka lōʻihi o ka manawa o nā poʻo hina Episodic ma waena o nā huhui o nā poʻo poʻo. ʻOi aku ka pōkole o nā manawa i nā poʻo hina puʻupuʻu ma waena o nā puʻupuʻu headache.

ʻAʻole i hoʻāʻo ʻia ʻo Aimovig no ka pale ʻana i ka huhū o ka huhui cluster i nā noiʻi maʻi. Eia nō naʻe, ua hoʻāʻo ʻia nā lāʻau ʻē aʻe i pili i ka papa like o nā lāʻau lapaʻau e like me Aimovig, me Emgality a me Ajovy.

I loko o kahi noiʻi hoʻokolohua, ua loaʻa ʻo Emgality e kōkua i ka pale ʻana i nā poʻo hina episodic. Akā no kahi hoʻokolohua hoʻokolohua o Ajovy, ua hoʻōki koke ka mea hana lāʻau i ke aʻo ʻana no ka mea ʻaʻole ʻo Ajovy e hana e hōʻemi i ka nui o nā poʻo hina puʻupuʻu mau no nā poʻe i ke aʻo ʻana.

ʻO Aimovig no nā poʻo hina vestibular

ʻAʻole ʻae ʻia ʻo Aimovig e ʻākoʻo iā FDA e pale a mālama paha i nā poʻo hina vestibular. ʻOkoʻa nā poʻo o Vestibular mai nā headache maʻamau o migraine no ka mea ʻaʻole maʻamau ka ʻeha. Pīhoihoi paha ka poʻe me nā poʻo hina vestibular a i ʻole ʻike i ka vertigo. E mau kekona paha kēia mau ʻōuli i mau hola.

ʻAʻole i hana ʻia nā noiʻi noiʻi e hōʻike inā maikaʻi ʻo Aimovig i ka pale ʻana a i ʻole ka mālama ʻana i nā poʻo hina vestibular. Akā koho paha kekahi mau kauka e kuhikuhi i ka lāʻau hōʻailona ma waho no kēia ʻano.

ʻ .kuhi Aimovig

ʻO ka lāʻau Aimovig i kuhikuhi ʻia e kāu kauka e pili ana i nā kumu he nui. Hoʻopili kēia i ke koʻikoʻi o ke ʻano āu e hoʻohana nei iā Aimovig e mālama ai.

ʻO ka maʻamau, e hoʻomaka kāu kauka iā ʻoe ma kahi lāʻau haʻahaʻa a hoʻomaʻamaʻa iā ia i ka manawa e hiki i ke ana pono kūpono iā ʻoe. Na lākou e kuhikuhi i ka mea liʻiliʻi loa e hāʻawi i ka hopena i makemake ʻia.

Hōʻike ka ʻikepili aʻe i nā lāʻau i hoʻohana pinepine ʻia a koi ʻia paha. Eia nō naʻe, e mālama pono i nā lāʻau a ke kauka i kuhikuhi ai nāu. E hoʻoholo kāu kauka i ke ana ʻoi loa e kūpono i kāu mau pono.

Nā ʻano a me nā ikaika

Hele mai ʻo Aimovig i kahi mahele lāʻau hoʻokahi, preinfile autoinjector i hoʻohana ʻia e hāʻawi i kahi inikoki subcutaneile (kahi kuʻi e hele ma lalo o ka ʻili). Hele mai ka autoinjector i hoʻokahi ikaika: 70 mg no ka pahu kui. Hoʻohana ʻia kēlā me kēia autoinjector i hoʻokahi wale nō a laila hoʻolei ʻia.

Nā hana no migraine

Hiki ke kuhikuhi ʻia ʻo Aimovig i ʻelua mau lā: 70 mg a i ʻole 140 mg. Lawe ʻia kekahi mahele lāʻau i hoʻokahi manawa i kēlā me kēia mahina.

Inā kau kauka i 70 mg, hāʻawi ʻoe iā ʻoe iho i hoʻokahi injection i kēlā me kēia mahina (e hoʻohana ana i hoʻokahi autoinjector). Inā kēnā kāu kauka iā 140 mg, hāʻawi ʻoe iā ʻoe i ʻelua injection i kēlā me kēia mahina, hoʻokahi ma hope o kekahi (e hoʻohana ana i ʻelua mau autoinjectors).

E hoʻomaka kāu kauka i kāu lapaʻau ma 70 mg i kēlā me kēia mahina. Inā ʻaʻole e hoʻoliʻiliʻi kēia ana i kāu helu o nā lā migraine i lawa, hiki i kāu kauka ke hoʻonui i kāu mea i 140 mg i kēlā me kēia mahina.

He aha inā e haʻo wau i kahi lāʻau?

E lawe i kahi lāʻau lapaʻau ke ʻike ʻoe ua hala ʻoe i hoʻokahi. ʻO kāu kau ma hope aʻe he hoʻokahi mahina ma hope o kēlā. E hoʻomanaʻo i ka lā hou i hiki ai iā ʻoe ke hoʻolālā no nā kau o ka wā e hiki mai ana.

Pono wau e hoʻohana i kēia lāʻau lōʻihi?

Inā maikaʻi ʻo Aimovig i ka pale ʻana i ka headache o ka ulu o ka maʻi iā ʻoe, e hoʻoholo paha ʻoe a me kāu kauka e hoʻomau i ka mālama ʻana me Aimovig i kahi wā lōʻihi.

Nā koho ʻē aʻe iā Aimovig

Loaʻa nā lāʻau ʻē aʻe e kōkua i ka pale ʻana i ka maʻi migraine. E hana maikaʻi paha kekahi iā ʻoe ma mua o nā mea ʻē aʻe. Inā hoihoi ʻoe i ka hoʻāʻo ʻana i kahi lāʻau ʻē aʻe ma mua o Aimovig, e kamaʻilio me kāu kauka e aʻo hou aʻe e pili ana i nā lāʻau ʻē aʻe e holo pono paha iā ʻoe.

ʻO nā laʻana o nā lāʻau ʻē aʻe i ʻae ʻia e ka FDA no ka pale ʻana i ka maʻi migraine me:

• nā peptide (CGRP) pili pū kekahi i ka ʻaoʻao pili pū kekahi.
• fremanezumab-vrfm (Ajovy)
• galcanezumab-gnlm (Emgality)
• kekahi mau lāʻau i hopu ʻia, e like me:
• divalproex sodium (Depakote)
• topiramate (Topamax, Trokendi XR)
• ka neurotoxin onabotulinumtoxinA (Botox)
• ka beta-blocker propranolol (Inderal, Inderal LA)

Hoʻohana ʻia kekahi mau lāʻau i ka lepili e pale aku ai i ka ʻeha o ka migraine. Hoʻopili kēia mau lāʻau:

• kekahi mau antidepressants, e like me amitriptyline a i ʻole venlafaxine (Effexor XR)
• kekahi mau lāʻau hopu, e like me ka valproate sodium
• kekahi mau beta-blockers, e like me metoprolol (Lopressor, Toprol XL) a i ʻole atenolol (Tenormin)

Nā mea kūʻē CGRP

ʻO Aimovig kahi ʻāpana o kahi papa hou o nā lāʻau i kapa ʻia he antagonists peptide (CGRP) e pili ana i ka ʻenekia. Ua ʻae ʻia ʻo Aimovig e ka FDA i ka makahiki 2018 e pale aku ai i ka ʻeha o ka migraine. Ua ʻae hou ʻia ʻelua mau mea ʻino CGRP i kapa ʻia ʻo Ajovy a me Emgality. E manaʻo ʻia e ʻāpono koke ʻia kahi lāʻau ʻehā o kēia papa (eptinezumab).

Pehea lākou e hana ai

Hana nā mea ʻaelike CGRP i ʻae ʻia i nā ala like e pale ai i ka ulu o ka migraine.

ʻO ka CGRP kahi protein i kou kino i hoʻopili ʻia me ka mumū a me ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) i ka lolo. Hiki i kēia mumū a me ka vasodilation ke hopena i ka ʻeha mai ka ulu poʻo o ka migraine. I mea e hopena ai i kēia mau hopena, pono ʻo CGRP e hoʻopaʻa (hoʻopili) i kāna mau mea loaʻa, ʻo ia nā pūnaewele ma ka ʻili o kekahi o kou mau lolo.

Hana ʻo Ajovy a me Emgality i ka paʻa ʻana iā CGRP iho. ʻO ka hopena, ʻaʻole hiki iā CGRP ke hoʻopaʻa i kāna mau mea loaʻa. ʻAʻole like me nā lāʻau ʻelua ʻē aʻe i kēia papa, hana ʻo Aimovig ma ka hoʻopaʻa ʻana i nā mea loaʻa nā lolo. Pale kēia i ka CGRP mai ka hana ʻana i kēia.

Ma ka pale ʻana iā CGRP mai ka launa pū ʻana me kāna mea loaʻa, kōkua nā lāʻau ʻekolu i ka hoʻopau ʻana i ka mumū a me ka vasodilation. Hiki i kēia ke kōkua i ka pale ʻana i ka maʻi migraine.

ʻAoʻao ma ka ʻaoʻao

Hoʻohālikelike ka pakuhi ma lalo i ka ʻike pili e pili ana i nā lāʻau ʻekolu i ʻae ʻia e ka FDA i kēia papa i hoʻohana ʻia e pale aku ai i ka ʻeha o ka migraine. E aʻo hou aʻe e pili ana i ka hoʻohālikelike ʻana o Aimovig me kēia mau lāʻau ʻē aʻe, e ʻike i ka ʻāpana aʻe ("Aimovig vs. nā lāʻau ʻē aʻe").

* Hiki ke hoʻololi i nā kumukūʻai ma muli o kāu wahi, ka hale kūʻai lāʻau i hoʻohana ʻia, kāu uhi ʻinikua, a me nā polokalamu kōkua mea hana.

Aimovig vs. nā lāʻau ʻē aʻe

Mahalo paha ʻoe pehea e hoʻohālikelike ai ʻo Aimovig i nā lāʻau ʻē aʻe i kuhikuhi ʻia no nā hoʻohana like. Ma lalo nā hoʻohālikelike ma waena o Aimovig a me kekahi mau lāʻau.

Aimovig vs. Ajovy

Aia i loko o Aimovig ka lāʻau lapaʻau erenumab, kahi he monoclonal antibody. Aia ʻo Ajovy i ka lāʻau fremanezumab, a he monoclonal antibody nō hoʻi. ʻO nā mea pale mū Monoclonal nā lāʻau i hana ʻia i loko o kahi lab. Hoʻomohala ʻia kēia mau lāʻau mai nā hunaola pūnaewele pale. Hana lākou ma ka pale ʻana i ka hana o kekahi mau protein i kou kino.

Hoʻopaʻa ʻo Aimovig lāua ʻo Ajovy i ka hana o kahi protein i kapa ʻia ʻo ka peptide pili i ka ʻenekene kalona (CGRP). ʻO ka CGRP ke kumu o ka mumū a me ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) i ka lolo, kahi e hopena ai i ka ʻeha o ka migraine. Kōkua ka pale ʻana iā CGRP i ka pale ʻana i ka maʻi migraine.

Hoʻohana

ʻO ʻAimovig lāua ʻo Ajovy ʻelua i ʻae ʻia e ka FDA e pale i ka ulu ʻana o ka ulu o ka migraine i nā mākua.

Nā ʻano a me ka hoʻokele

Hele mai ʻo Aimovig lāua ʻo Ajovy i kahi ʻano injectable i lawelawe ʻia ma lalo o kou ʻili (subcutaneous). Hiki iāʻoe ke hāʻawi iāʻoe iho i ka home. Hiki ke hōʻeha ʻia nā lāʻau ʻelua i kekahi mau wahi, e like me:

• kou ʻōpū
• ʻo ka mua o kou mau ʻūhā
• ke kua o kou mau lima luna

Hāʻawi ʻia ʻo Aimovig ma ke ʻano he autoinjector prefilled pre-full. Hāʻawi pinepine ʻia ma ke ʻano he 70-mg injection i hoʻokahi manawa i kēlā me kēia mahina. Eia nō naʻe, kuhikuhi ʻia kekahi poʻe i kahi lāʻau ʻoi loa o 140 mg i kēlā me kēia mahina.

Hāʻawi ʻia ʻo Ajovy ma ke ʻano he syringe prefilled hoʻokahi lāʻau. Hiki ke hāʻawi ʻia ma ke ʻano he hoʻokahi injection 225 mg i hoʻokahi manawa i kēlā me kēia mahina. A i ʻole hiki ke hāʻawi ʻia ma ke ʻano he ʻekolu injection o 225 mg hoʻokahi manawa i kēlā me kēia ʻekolu mahina.

Nā hopena a me nā pilikia

Hana ʻo Aimovig lāua ʻo Ajovy i nā ala like a hana i kekahi o nā hopena ʻaoʻao like. ʻO nā hopena maʻamau a koʻikoʻi o nā lāʻau ʻelua ma lalo.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Aimovig, me Ajovy, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Aimovig:
• kōpaʻa
• ʻūpī mākala a i ʻole nā ​​spasms
• luna maʻiʻaʻai maʻiʻaʻai (e like me ka maʻamau anu a me ka sinus maʻiʻaʻai)
• nā ʻōuli like flu
• ʻeha kua
• Hiki ke hana me Ajovy:
• ʻaʻohe kū hoʻokahi hopena ʻaoʻao
• Hiki ke hana me nā Aimovig a me Ajovy:
• ʻO nā hopena o ka pūnaewele injection e like me ka ʻeha, ʻili, a ʻulaʻula paha

Nā hopena hopena koʻikoʻi

ʻO ka hopena koʻikoʻi koʻikoʻi no Aimovig a me Ajovy kahi hopena maʻi maʻi. ʻAʻole maʻamau kēlā ʻano hopena, akā hiki nō naʻe. (No ka 'ike hou aku, e nānā i ka "Allergic react" ma lalo o "Aimovig hopena hopena" ma luna).

Hopena Immune

I nā hoʻokolohua hoʻokolohua i hana ʻia no Aimovig a me Ajovy, he hapa liʻiliʻi o ka poʻe i loaʻa i ka hopena pale i nā lāʻau. Ua hana ka hopena i ko lākou kino e hoʻomohala i nā mea pale kūʻē i nā lāʻau.

ʻO nā Antibodies nā protein i hana ʻia e ka ʻōnaehana pale e kaua aku i nā mea haole i kou kino. Hiki i kou kino ke hoʻomohala i nā mea pale i nā mea haole, e like me nā monoclonal antibodies. Inā hana kou kino i nā mea ʻawa iā Aimovig a i ʻole Ajovy, ʻaʻole holo pono paha ka lāʻau iā ʻoe.

I nā hoʻokolohua hoʻokolohua no Aimovig, ʻoi aku ma mua o 6 pākēneka o nā kānaka i hoʻomohala i nā mea pale i ka lāʻau. I ka hoʻomau ʻana i ka noiʻi haukapila, ʻoi aku ka liʻiliʻi ma mua o 2 pākēneka o ka poʻe i hoʻomohala i nā mea pale maʻi i Ajovy.

Ma muli o ka ʻae ʻia ʻo Aimovig lāua ʻo Ajovy i ka makahiki 2018, hiki wawe loa ka ʻike ʻana i ke ʻano o ka hopena o kēia hopena a pehea e hoʻopili ai i ka hoʻohana ʻana o ka poʻe i kēia mau lāʻau i ka wā e hiki mai ana.

Ka hoʻokō ʻana

Kūpono ʻo Aimovig lāua ʻo Ajovy i ka pale ʻana i ka maʻi migraine, akā ʻaʻole i hoʻohālikelike pololei ʻia i nā hoʻokolohua hoʻokolohua.

Eia nō naʻe, kuhikuhi nā kulekele lapaʻau migraine i kekahi lāʻau i koho ʻia no kekahi poʻe. Hoʻopili kēia i ka poʻe nāna:

• ʻaʻole hiki ke hōʻemi i ko lākou mau lā neʻe o ka mahina me ka nui o nā lāʻau
• ʻaʻole hiki ke hoʻomanawanui i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole nā ​​launa ʻana o ka lāʻau

ʻO migraine Episodic

Hoʻokaʻawale nā ​​noiʻi o Aimovig a me Ajovy i ka maikaʻi no ka pale ʻana i ka episodic migraine headache.

• I nā noiʻi olakino o Aimovig, ma kahi o 40 pākēneka o ka poʻe me ka migraine episodic i loaʻa he 70 mg o ka lāʻau i kēlā me kēia mahina ʻokiʻoki i ko lākou mau lā migraine ma ka liʻiliʻi o ka hapalua ma mua o ʻeono mau mahina. Aia i 50 pakeneka o ka poʻe i loaʻa ka 140 mg i loaʻa nā hopena like.
• I loko o kahi noiʻi olakino o Ajovy, ma kahi o 48 ka pākēneka o ka poʻe me ka migraine episodic i loaʻa i ka mālama ʻana i kēlā me kēia mahina me ka lāʻau ʻokiʻoki i ko lākou lā migraine ma ka liʻiliʻi o ka hapalua ma mua o ʻekolu mau mahina. Ma kahi o 44 pākēneka o ka poʻe i loaʻa iā Ajovy i kēlā me kēia ʻekolu mahina i loaʻa nā hopena like.

Pilikia waikiki

Hoʻokaʻawale nā ​​noiʻi o Aimovig a me Ajovy i ka maikaʻi no ka pale ʻana i ka maʻi migraine mau.

• I loko o kahi noiʻi ʻekolu mahina o Aimovig, ma kahi o 40 pākēneka o ka poʻe me ka migraine maʻi mau i loaʻa iā 70 mg a i ʻole 140 mg o ka lāʻau i kēlā me kēia mahina he hapa ka nui o nā lā o ka migraine a ʻoi aku paha.
• I loko o kahi noiʻi ʻekolu mahina o Ajovy, ʻaneʻane 41 pākēneka o ka poʻe me ka migraine maʻi mau i loaʻa i kēlā me kēia mahina Ajovy therapy i ka hapalua o nā lā o ka migraine ma hope o ka lapaʻau ʻana a ʻoi aku paha. ʻO ka poʻe i loaʻa iā Ajovy i kēlā me kēia ʻekolu mau mahina, ma kahi o 37 pākēneka he mau hopena like.

Nā kumukūʻai

ʻO Aimovig lāua ʻo Ajovy nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe ʻano generic o nā lāʻau i loaʻa. ʻOi aku ka uku o nā lāʻau lapaʻau inoa inoa ma mua o nā ʻano generic.

Ma muli o nā koho mai GoodRx.com, ʻo Aimovig lāua ʻo Ajovy ke kumu kūʻai o ke kālā like. ʻO ke kumukūʻai maoli āu e uku ai no kēlā me kēia lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai. Pili kāu kumu kūʻai no Aimovig i kāu lāʻau.

Aimovig vs. Botox

Aia i loko o Aimovig kahi antibody monoclonal i kapa ʻia ʻo erenumab. ʻO kahi antibody monoclonal kahi ʻano lāʻau i hoʻomohala ʻia i kahi lab. Hana ʻia kēia mau lāʻau mai nā hunaola pūnaewele pale. Hana ʻo Aimovig e pale i ka huhū o ka migraine ma ka pale ʻana i ka hana o kahi protein kikoʻī e hiki ke kumu iā lākou.

Loaʻa i ka Botox ka lāʻau onabotulinumtoxinA. Pili kēia lāʻau i kekahi papa o nā lāʻau i kapa ʻia neurotoxins. Hana ʻo Botox e ka palaka manawa ʻana i nā mākala i ʻomo ʻia i loko. Pale kēia hopena i nā hōʻailona ʻeha i nā mākala mai ka hoʻoulu ʻia.Manaʻo ʻia he kōkua kēia hana i ka pale ʻana i ka maʻi migraine ma mua o ka hoʻomaka ʻana.

Hoʻohana

Ua ʻae ʻia ʻo Aimovig e ka FDA e pale aku i ka episodic a i ʻole ka maʻi migraine maʻi mau i nā mākua.

Ua ʻae ʻia ʻo Botox e pale i ka hōʻeha ʻana o ka migraine mau i nā mākua. ʻAe ʻia ʻo Botox e mālama i nā ʻano kumu ʻē aʻe, e like me:

• cerny dystonia (ʻeha ʻeha wili)
• ʻōniu maka
• ʻōpū hū
• spasticity mānoanoa
• sweating nui loa

Nā ʻano a me ka hoʻokele

Hele mai ʻo Aimovig ma ke ʻano he autoinjector prefilled hoʻokahi mahele lāʻau. Hāʻawi ʻia ia ma ke ʻano he injection i lalo o kou ʻili (subcutaneous) hiki iā ʻoe ke hāʻawi iā ʻoe iho ma ka home. Hāʻawi ʻia ia ma kahi mahele o 70 mg a i ʻole 140 mg i kēlā me kēia mahina.

Hiki ke hoʻopili ʻia ʻo Aimovig i kekahi mau wahi o ke kino. Eia nā:

• kou ʻōpū
• ʻo ka mua o kou mau ʻūhā
• ke kua o kou mau lima luna

Hāʻawi wale ʻia ʻo Botox i ke keʻena o ke kauka. Hoʻokomo ʻia me ka syringe i loko o kahi mākala (intramuscular), ma ka maʻamau i kēlā me kēia 12 pule. ʻO nā pūnaewele maʻamau no ka hoʻopili ʻana:

• kou lae
• ka hope o kou ʻāʻī a me kou poʻohiwi
• ma luna a kokoke i kou mau pepeiao
• kokoke i kāu kaula lauoho ma ke kumu o kou ʻāʻī

Hāʻawi pinepine kāu kauka iā ʻoe i 31 mau injection liʻiliʻi i kēia mau wahi i kēlā me kēia kau.

Nā hopena a me nā pilikia

Hoʻohana ʻia ʻo Aimovig lāua ʻo Botox i mea e pale aku ai i ka maʻi migraine, akā hana lākou i nā ʻano like ʻole. No laila, he ʻano like ko lākou a me kekahi ʻokoʻa.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Aimovig, me Botox, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Aimovig:
• kōpaʻa
• ʻūpē mākala
• pulupulu nā mākala
• ʻeha kua
• luna maʻiʻaʻai maʻiʻaʻai (e like me ka maʻamau anu a me ka sinus maʻiʻaʻai)
• Hiki ke hana me Botox:
• ʻeha ʻeha a i ʻole migrain worsening
• ʻōlohelohe maka
• lolo palaka
• ʻeha ʻāʻī
• ʻoʻoleʻa o ka mākala
• ʻehaʻeha a me nāwaliwali
• Hiki ke hana me nā Aimovig a me Botox:
• nā hopena kahua pūnaewele injection
• nā ʻōuli like flu

Nā hopena hopena koʻikoʻi

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Aimovig, me Botox, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Aimovig:
• kekahi mau hopena koʻikoʻi koʻikoʻi
• Hiki ke hana me Botox:
• ka palahalaha ʻana o ka maʻi lōlō i nā mākala kokoke *
• pilikia i ka ale ʻana a me ka hanu ʻana
• maʻi kūpilikiʻi
• Hiki ke hana me nā Aimovig a me Botox:
• hopena hopena maikaʻi

* He ʻōlelo aʻoaʻo a Botox mai ka FDA no ka hoʻolaha ʻana o ka maʻi lōlō i nā io kokoke e ukali ana i ka ʻume. ʻO kahi ʻōlelo aʻoaʻo i pahu ʻia ka ʻōlelo aʻo ikaika a ka FDA e koi ai. Hoʻomaopopo ia i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

Ka hoʻokō ʻana

ʻO ke kūlana wale nō e hoʻohana ʻia ai ʻo Aimovig a me Botox e pale ai i ka maʻi migraine maʻi mau.

Paipai nā kulekele lapaʻau iā Aimovig ma ke ʻano he koho no ka poʻe hiki ʻole ke hōʻemi i kā lākou helu o nā lā migraine i lawa me nā lāʻau ʻokoʻa. Paipai ʻia no ka poʻe hiki ʻole ke lawe i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole nā ​​launa ʻana o ka lāʻau.

Paipai ʻia ʻo Botox e ka American Academy of Neurology ma ke ʻano he koho no ka mālama ʻana i ka poʻe me ka migraine mau.

ʻAʻole i hoʻohālikelike pololei ʻia ka maikaʻi o kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, i loko o nā noiʻi ʻokoʻa, ua loaʻa nā hopena maikaʻi i ka Aimovig a me Botox i ka pale ʻana i ka maʻi migraine mau.

• I kahi noiʻi olakino o Aimovig, ma kahi o 40 pākēneka o ka poʻe me ka migraine maʻi mau i loaʻa iā 70 mg a i ʻole 140 mg i ka hapalua o nā lā o ka migraine a i ʻole ka liʻiliʻi ma hope o ʻekolu mau mahina.
• I nā noiʻi hoʻokolohua o ka poʻe me ka migraine maʻi mau, ua hoʻemi ʻo Botox i ka helu o nā lā headache a hiki i ka 9.2 lā ma ka awelika o kēlā me kēia mahina, ma luna o 24 mau pule. Ma kahi noiʻi ʻē aʻe, ma kahi o 47 ka pākēneka o ka poʻe i hoʻemi i kā lākou helu o nā lā maʻi ʻeha ma ka liʻiliʻi o ka hapalua.

Nā kumukūʻai

ʻO Aimovig lāua ʻo Botox nā lāʻau lapaʻau inoa inoa ʻelua. ʻAʻohe o nā ʻano laulā i loaʻa i kekahi lāʻau paha.

Wahi a nā koho mai GoodRx.com, ʻoi aku ka liʻiliʻi o ka pipiʻi o Botox ma mua o Aimovig. ʻO ke kumukūʻai maoli āu e uku ai no nā lāʻau ʻelua e pili ana i kāu lāʻau, hoʻolālā inikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

ʻO Aimovig vs. Emgality

Aia i loko o Aimovig kahi antibody monoclonal i kapa ʻia ʻo erenumab. Aia i loko o Emgality kahi antibody monoclonal i kapa ʻia ʻo galcanezumab. ʻO kahi antibody monoclonal kahi ʻano lāʻau i hoʻomohala ʻia i kahi lab. Hana ʻia kēia mau lāʻau mai nā hunaola pūnaewele pale. Hana lākou ma ka pale ʻana i ka hana o nā protein ponoʻī i kou kino.

ʻO Aimovig a me Emgality ka mea āpau i ka hana o kahi protein i kou kino i kapa ʻia ʻo ka peptide pili pili i ka ʻenekene kalona (CGRP). Hana ʻo CGRP i ka mumū a me ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) i ka lolo, kahi e hopena ai i ka ulu ʻana o ka migraine. Ma ke kāpae ʻana i ka hana o CGRP, kōkua kēia mau lāʻau i ka hoʻōki ʻana i ka mumū a me ka vasodilation. Kōkua kēia i ka pale ʻana i ka huhū o ka migraine.

Hoʻohana

ʻO Aimovig a me Emgality ʻelua a ʻAmelika i ʻae ʻia e pale i ka hōʻeha ʻana o ka migraine i nā mākua.

Nā ʻano a me ka hoʻokele

Hāʻawi ʻia ʻo Aimovig i loko o kahi autoinjector prefilled pre-full. Hāʻawi ʻia ʻo Emgality i kahi syringe prefilled hoʻokahi-mahele hoʻokahi a me kahi peni peni piha i hoʻokahi lāʻau. Hāʻawi ʻia nā lāʻau ʻelua ma ke ʻano he subcutaneous injection (kahi injection ma lalo o ka ʻili). Hiki iā ʻoe ke hāʻawi i nā injection iā ʻoe iho ma ka home hoʻokahi i ka mahina.

Hiki ke ʻimi ʻia nā lāʻau ʻelua ma lalo o ka ʻili ma kekahi mau wahi o kou kino. Eia nā:

• kou ʻōpū
• ʻo ka mua o kou mau ʻūhā
• ke kua o kou mau lima luna

Hiki pū ʻia hoʻi ka emgality ma lalo o ka ʻili o kou puʻupuʻu.

Kau ʻia ʻo Aimovig ma ke ʻano he 70-mg a i ʻole 140-mg i kēlā me kēia mahina. Kau ʻia ʻo Emgality ma ke ʻano he 120-mg injection injection.

Nā hopena a me nā pilikia

ʻO Aimovig a me Emgality nā lāʻau like e hana ai i kekahi o nā hopena ʻaoʻao maʻamau a koʻikoʻi hoʻi. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Aimovig, me Emgality, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Aimovig:
• kōpaʻa
• ʻūpē mākala
• pulupulu nā mākala
• nā ʻōuli like flu
• Hiki ke hana me Emgality:
• eha ka 'ā'ī
• Hiki ke hana me nā Aimovig a me Emgality:
• nā hopena kahua pūnaewele injection
• ʻeha kua
• luna maʻiʻaʻai maʻi maʻi maʻiʻaʻai (e like me ka maʻamau anu a me ka sinus maʻiʻaʻai)

Nā hopena hopena koʻikoʻi

ʻO ka hopena ʻino loa he hopena koʻikoʻi koʻikoʻi ia no Aimovig a me Emgality. (No ka 'ike hou aku, e nānā i ka "Allergic react" ma lalo o "Aimovig hopena hopena" ma luna).

Hopena Immune

I nā hoʻokolohua hoʻokolohua no kēlā me kēia lāʻau, he heluna liʻiliʻi o nā kānaka i loaʻa i kahi hopena pale iā Aimovig a me Emgality. Me kēia ʻano hopena, ua hoʻomohala ka ʻōnaehana pale ʻino o ke kino i nā mea pale kūʻē i nā lāʻau.

ʻO nā Antibodies nā protein i loko o kāu ʻōnaehana pale pale kaua i nā mea ʻē i kou kino. Hiki i kou kino ke hana i nā mea pale i nā mea haole, e like me nā monoclonal antibodies e like me Aimovig a me Emgality.

Inā hoʻomohala kou kino i nā mea pale i kekahi o kēia mau lāʻau, hiki i ka lāʻau ke hana hou ʻole e pale aku i ka ʻeha o ka migraine iā ʻoe.

I nā noiʻi olakino o Aimovig, ʻoi aku ma mua o 6 pākēneka o ka poʻe e lawe nei i ka lāʻau i hoʻomohala iā ia. A i loko o nā noiʻi hoʻokolohua o Emgality, ʻaneʻane 5 pākēneka o ka poʻe i hoʻomohala i nā mea pale i Emgality.

Ma muli o ka ʻae ʻia ʻo Aimovig a me Emgality i ka makahiki 2018, ua ʻeleu loa ia e ʻike i ka nui o ka poʻe i loaʻa i kēia ʻano ʻano. Ma mua loa ia e ʻike pehea e hiki ai i ka hopena ke hoʻohana ka poʻe i kēia mau lāʻau i ka wā e hiki mai ana.

Ka hoʻokō ʻana

ʻAʻole hoʻohālikelike ʻia ʻo Aimovig a me Emgality i nā noiʻi maʻi, akā maikaʻi nā mea ʻelua no ka pale ʻana i ka ulu o ka migraine.

Paipai nā kulekele lapaʻau iā Aimovig a me Emgality i mau koho no nā poʻe me ka episodic a i ʻole migraine maʻi mau:

• ʻaʻole hiki ke lawe i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole nā ​​launa ʻana o ka lāʻau
• ʻaʻole hiki ke hōʻemi i kā lākou helu o nā lā migraine o ka mahina i lawa me nā lāʻau ʻē aʻe

ʻO migraine Episodic

Hoʻokaʻawale nā ​​noiʻi o Aimovig a me Emgality i hōʻike ʻia he maikaʻi nā lāʻau ʻelua no ka pale ʻana i ka maʻi migraine episodic:

• I nā noiʻi olakino o Aimovig, a hiki i ka 50 pākēneka o ka poʻe me ka migraine episodic i loaʻa 140 mg o ka lāʻau i hoʻemi i ko lākou lā migraine e ka hapa ma mua o ʻeono mau mahina. Ma kahi o 40 pākēneka o ka poʻe i loaʻa ka 70 mg i ʻike i nā hopena like.
• I loko o ka Emgality's clinical haʻawina o ka poʻe me episodic migraine, ma kahi o 60 pākēneka o ka poʻe i hoʻemi i ko lākou helu o nā lā migraine ma ka liʻiliʻi o ka hapalua ma mua o ʻeono mau mahina o ka mālama ʻana iā Emgality. Hiki i ka 16 pākēneka ke ʻole migraine ma hope o nā malama eono o ka mālama ʻana.

Pilikia waikiki

Hoʻokaʻawale nā ​​noiʻi o Aimovig a me Emgality i hōʻike ʻia he maikaʻi nā lāʻau ʻelua no ka pale ʻana i ka maʻi migraine mau.

• I loko o kahi noiʻi ʻekolu mau mahina o ka poʻe me ka migraine mau, ma kahi o 40 pākēneka o ka poʻe i lawe i 70 mg a i ʻole 140 mg o Aimovig i ka hapalua o nā lā o ka migraine a ʻoi aku paha me ka lāʻau lapaʻau.
• I loko o kahi noiʻi ʻekolu mahina o ka poʻe me ka migraine mau, ʻaneʻane 30 pākēneka o ka poʻe i lawe iā Emgality no ʻekolu mau mahina i ka hapalua o nā lā o ka migraine a ʻoi aku paha me ka lāʻau lapaʻau.

Nā kumukūʻai

ʻO Aimovig lāua ʻo Emgality nā lāʻau lapaʻau inoa inoa ʻelua. ʻAʻohe o nā ʻano laulā i loaʻa i kekahi lāʻau paha. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā wānana mai GoodRx.com, ua like ko Aimovig a me Emgality kumukūʻai like. ʻO ke kumukūʻai maoli āu e uku ai no nā lāʻau ʻelua e pili ana i kāu lāʻau, hoʻolālā inikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Aimovig vs. Topamax

Aia i loko o Aimovig kahi antibody monoclonal i kapa ʻia ʻo erenumab. ʻO kahi antibody monoclonal kahi ʻano lāʻau i hoʻomohala ʻia mai nā pūnaewele ʻōnaehana pale. Hana ʻia nā lāʻau o kēia ʻano i kahi lab. Kōkua ʻo Aimovig i ka pale ʻana i ka ʻeha o ka migraine ma o ka hoʻōki ʻana i ka hana o nā protein ponoʻī i kumu iā lākou.

Aia ʻo Topamax i ka topiramate, kahi ʻano o ka lāʻau i hoʻohana pū ʻia e mālama i ka hopu ʻana. ʻAʻole maopopo maikaʻi pehea ka Topamax e hana ai e pale i ka huhū o ka migraine. Manaʻo ʻia he hōʻemi ka lāʻau i nā hunaola nerve overactive i ka lolo e hiki ai ke hōʻeha i ka migraine.

Hoʻohana

Ua ʻĀpono ʻia ʻo Aimovig a me Topamax e pale i ka maʻi migraine. ʻAe ʻia ʻo Aimovig no ka hoʻohana ʻana i nā mākua, ʻoiai ʻo Topamax e ʻae ʻia no ka hoʻohana ʻana i nā mākua a me nā keiki o 12 a ʻoi paha makahiki.

ʻAe ʻia ʻo Topamax e mālama i ka maʻi epilepsy.

Nā ʻano a me ka hoʻokele

Hele mai ʻo Aimovig i kahi autoinjector prefilled pre-full. Hāʻawi ʻia ia ma ke ʻano he injection i lalo o kou ʻili (subcutaneous) āu e hāʻawi ai iā ʻoe iho ma ka home hoʻokahi i kēlā me kēia mahina. ʻO ka mahele maʻamau he 70 mg, akā pōmaikaʻi paha kekahi poʻe i kahi lāʻau 140-mg.

Hele mai ʻo Topamax ma ke ʻano he capsule waha a i ʻole papaha waha. ʻO ka maʻa maʻamau he 50 mg i lawe ʻia i ʻelua mau lā i kēlā me kēia lā. Kaukaʻi ʻia i ka ʻōlelo aʻoaʻo a kāu kauka, hoʻomaka paha ʻoe i kahi lāʻau haʻahaʻa a hoʻonui iā ia i ka hana maʻamau ma mua o ʻelua mau mahina.

Nā hopena a me nā pilikia

Hana ʻo Aimovig a me Topamax i nā ʻano like ʻole i ke kino a no laila loaʻa nā ʻaoʻao ʻokoʻa. Aia ma lalo kekahi o nā hopena hopena maʻamau a koʻikoʻi hoʻi o nā lāʻau ʻelua. ʻAʻole hoʻokomo ka papa inoa ma lalo i nā hopena ʻaoʻao āpau.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Aimovig, me Topamax, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Aimovig:
• nā hopena kahua pūnaewele injection
• ʻeha kua
• kōpaʻa
• ʻūpē mākala
• ʻūpē mākala
• nā ʻōuli like flu
• Hiki ke hana me Topamax:
• eha ka 'ā'ī
• luhi
• paresthesia (manaʻo o "pin a me nā nila")
• nausea
• pāhoehoe
• Kaumaha emi
• nalo ʻai ʻole
• pilikia pilikia
• Hiki ke hana me nā Aimovig a me Topamax:
• hanu maʻi maʻi maʻi (e like me ka maʻamau anu a me ka sinus maʻiʻaʻai)

Nā hopena hopena koʻikoʻi

Loaʻa i kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana ʻia me Aimovig, me Topamax, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Aimovig:
• kekahi mau hopena koʻikoʻi koʻikoʻi
• Hiki ke hana me Topamax:
• nā pilikia ʻike, me glaucoma
• hoʻoliʻiliʻi sweating (hiki ʻole ke hoʻokele i ka mahana o ke kino)
• acidosis metabolic
• nā manaʻo suicidal a me nā hana
• nā pilikia i manaʻo ʻia e like me nā pilikia huikau a me nā hoʻomanaʻo
• kaumaha
• encephalopathy (maʻi lolo)
• pōhaku kīhāpai
• mahuahua ka hopu 'ana i ka wā o ka lāʻau ua oki koke (ke hoʻohana' ia ka lāʻau no ka hopu 'ana)
• Hiki ke hana me nā Aimovig a me Topamax:
• hopena hopena maikaʻi

Ka hoʻokō ʻana

ʻO ke kumu wale nō ʻelua ʻo Aimovig a me Topamax i ʻae ʻia e FDA no ka pale ʻana i ka migraine.

Paipai nā ʻōkuhi hoʻomaʻamaʻa iā Aimovig ma ke ʻano he koho no ka pale ʻana i ka episodic a i ʻole ka maʻi migraine maʻi mau i ka poʻe nāna:

• ʻaʻole hiki ke lawe i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole nā ​​launa ʻana o ka lāʻau
• ʻaʻole hiki ke hōʻemi i kā lākou helu o ka ulu ʻana o ka migraine o ka mahina me ka lawa o nā lāʻau

Paipai nā kulekele lapaʻau iā Topiramate ma ke ʻano he koho no ka pale ʻana i ka maʻi migraine episodic.

ʻAʻole hoʻohālikelike pololei nā noiʻi maʻi i ka pono o kēia mau lāʻau ʻelua i ka pale ʻana i ka maʻi migraine. Akā ua aʻo ʻokoʻa ʻia nā lāʻau.

ʻO migraine Episodic

Ua hōʻike ʻokoʻa nā noiʻi o Aimovig a me Topamax i ka maikaʻi o nā lāʻau ʻelua i ka pale ʻana i ka ʻeha migraine episodic.

• I nā noiʻi olakino Aimovig, a hiki i ka 50 pākēneka o ka poʻe me ka migraine episodic i loaʻa 140 mg ʻokiʻoki i ko lākou lā migraine e ka hapa ma kahi o ʻeono mau mahina o ka lapaʻau. Ma kahi o 40 pākēneka o ka poʻe i loaʻa ka 70 mg i ʻike i nā hopena like.
• I loko o nā noiʻi olakino o ka poʻe me ka migraine episodic nāna i lawe iā Topamax, ʻo ka poʻe he 12 mau makahiki a ʻoi paha ka makahiki i loaʻa i ʻelua mau liʻiliʻi o ka migraine i kēlā me kēia mahina. ʻO nā keiki mai ka makahiki 12 a 17 a me ka migraine episodic i loaʻa i ʻekolu mau liʻiliʻi o ka migraine i kēlā me kēia mahina.

Pilikia waikiki

Ua hōʻike ʻokoʻa nā noiʻi ʻana o nā lāʻau i ka maikaʻi o ka Aimovig a me Topamax i ka pale ʻana i ka maʻi migraine mau.

• I loko o kahi noiʻi ʻekolu mau mahina o Aimovig, ma kahi o 40 pākēneka o nā kānaka me ka maʻi migraine maʻi mau i loaʻa he 70 mg a i ʻole 140 mg i ka hapalua o nā lā o ka migraine a ʻoi aku paha ma hope o ka lapaʻau.
• I loko o kahi noiʻi i nānā i nā hopena o nā hoʻokolohua hoʻokolohua i loaʻa i ka poʻe me ka migraine mau, ua hoʻemi ʻo Topamax i ka helu o ka ulu poʻo o ka migraine a ʻelima paha poʻo ma kahi o ʻelima a ʻeiwa i kēlā me kēia mahina.

Nā kumukūʻai

ʻO Aimovig lāua ʻo Topamax nā lāʻau lapaʻau inoa inoa ʻelua. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā lāʻau laulā. ʻAʻole loaʻa ʻo Aimovig i kahi ʻano laulā, akā hele mai ʻo Topamax ma ke ʻano he generic i kapa ʻia ʻo topiramate.

Wahi a nā wānana mai GoodRx.com, Topamax paha ke kumu kūʻai ʻoi aku a ʻoi aku paha ma mua o Aimovig, kaukaʻi ʻia i kāu kau. A ʻo topiramate, ke ʻano laulaha o Topamax, e uku ʻia ma lalo o Topamax a i ʻole Aimovig.

ʻO ke kumukūʻai maoli āu e uku ai no kekahi o kēia mau lāʻau e pili ana i kāu lāʻau, kāu hoʻolālā ʻinikua, kou wahi, a me ka hale kūʻai āu e hoʻohana ai.

ʻAimovig a me ka waiʻona

ʻAʻohe pilina ma waena o Aimovig a me ka waiʻona.

Eia nō naʻe, manaʻo paha kekahi poʻe ʻaʻole maikaʻi ka lāʻau inā inu lākou i ka waiʻona i ka wā e lawe ana iā Aimovig. ʻO kēia no ka mea hiki i ka waiʻona ke lilo i mea hoʻohuli migraine no nā poʻe he nui. ʻOiai ʻo ka liʻiliʻi o ka wai ʻona hiki ke hana i migraine no lākou.

Pono ʻoe e hōʻalo i nā mea inu i loaʻa ka waiʻona inā ʻike ʻoe i ka waiʻona e hōʻemi ai i ka ʻeha a i ʻole pinepine pinepine i ka ulu ʻana o ka migraine.

Nā pilina Aimovig

Hiki i nā lāʻau he nui ke launa pū me nā lāʻau ʻē aʻe. Hiki i nā hopena ʻokoʻa ke kumu ʻia e nā pilina like ʻole. ʻO kahi laʻana, hiki i kekahi mau launa pū ke hoʻopilikia me ka maikaʻi o ka hana ʻana o ka lāʻau, ʻoiai ʻo nā mea ʻē aʻe ke kumu i nā hopena ʻē aʻe.

ʻAʻohe maʻamau o Aimovig i nā launa lāʻau. ʻO kēia no ke ʻano o ka hana ʻana iā Aimovig i kou kino.

Pehea e hoʻohua ʻia ai ʻo Aimovig

Nui nā lāʻau, nā mea kanu, a me nā mea hoʻopihapiha i hoʻopili ʻia (hana ʻia) e nā enzymes i kou ake. Akā ʻaʻole mālama pinepine ʻia nā lāʻau monoclonal antibody, e like me Aimovig, i ke akepaʻa. Akā, hana ʻia kēia ʻano lāʻau i loko o nā hunaola ʻē aʻe i kou kino.

Ma muli o ka hana ʻole ʻia o Aimovig i ke akepaʻa e like me nā lāʻau ʻē aʻe he nui, ʻaʻole launa pū ia me nā lāʻau ʻē aʻe.

Inā he hopohopo kāu e pili ana i ka hoʻohui ʻana iā Aimovig me nā lāʻau ʻē aʻe āu e lawe nei, e kamaʻilio pū me kāu kauka. A e ʻike pono e haʻi iā lākou e pili ana i nā kuhikuhi āpau, over-the-counter, a me nā lāʻau ʻē aʻe āu e lawe ai. Pono ʻoe e haʻi iā lākou e pili ana i nā mea kanu, nā wikamina, a me nā mea hoʻopili pono ʻole āu e hoʻohana ai.

Nā ʻōkuhi pehea e lawe ai iā Aimovig

Hele mai ʻo Aimovig ma ke ʻano he injection i hāʻawi ʻia ma lalo o kou ʻili (subcutaneous). Hāʻawi ʻoe iā ʻoe iho i ka ʻume ma ka home hoʻokahi i kēlā me kēia mahina. ʻO ka manawa mua e kiʻi ai i kahi kauka no Aimovig, e wehewehe ana kāu kauka lawelawe pehea e hāʻawi ai iā ʻoe iho i ka ʻume.

Hele mai ʻo Aimovig i kahi lāʻau hoʻokahi (70 mg) autoinjector. Hoʻokahi wale nō mahele lāʻau kēlā me kēia autoinjector a makemake ʻia e hoʻohana hoʻokahi a laila hoʻolei ʻia. (Inā kau kauka i 140 mg i kēlā me kēia mahina, e hoʻohana ʻoe i ʻelua mau autoinjectors i kēlā me kēia mahina.)

Ma lalo iho nei ka ʻike e pili ana i ka hoʻohana ʻana i ka syringe i hana mua ʻia. No nā kikoʻī ʻē aʻe, wikiō, a me nā kiʻi o nā ʻōkuhi injection, e ʻike i ka pūnaewele o ka mea hana.

Pehea e hoʻopili ai

Kau kauka kāu 70 mg i hoʻokahi manawa i kēlā me kēia mahina a i ʻole 140 mg i hoʻokahi manawa i kēlā me kēia mahina. Inā kuhikuhi ʻoe iā 70 mg i kēlā me kēia mahina, hāʻawi ʻoe iā ʻoe iho i hoʻokahi injection. Inā kuhikuhi ʻoe iā 140 mg i kēlā me kēia mahina, e hāʻawi ʻoe iā ʻoe iho i ʻelua injection ʻokoʻa, ʻo kekahi ma hope o kekahi.

Ke hoʻomākaukau nei e hoʻokomo

• Lawe i kāu Aimovig autoinjector mai ka pahu hau 30 mau minuke ma mua o kou hoʻolālā e hana i kāu injection. ʻAe kēia e hoʻomehana i ka lāʻau i ke ana wela o ka lumi. E waiho i ka pāpale ma ka mea pono autoinjector a mākaukau ʻoe e hoʻopili i ka lāʻau.
• Mai hoʻāʻo e hoʻomehana i ka autoinjector me ka wikiwiki e ka microwaving iā ia a i ʻole ka holo ʻana o ka wai wela ma luna ona. Eia kekahi, mai hoʻoluliluli i ka autoinjector. ʻO ka hana ʻana i kēia mau mea hiki ke hōʻemi iā Aimovig me ka palekana a me ka maikaʻi.
• Inā ʻoe e hāʻule hāʻule ʻole i ka autoinjector, mai hoʻohana ia. E haki paha nā mea liʻiliʻi o ka autoinjector i loko, ʻoiai inā ʻaʻole hiki iā ʻoe ke ʻike i kahi hōʻino.
• ʻOiai ʻoe e kali nei no Aimovig e hele mai i ka mahana wela, e ʻike i nā lako ʻē aʻe āu e pono ai. Pākuʻi ʻia kēia mau mea:
• he holoi wai ʻino
• pōpō pulupulu a me ka ʻuluma paha
• kāʻei kāpili
• ipu hoʻolei no sharps
• E hōʻoia i ka autoinjector a hōʻoia i ka nānā ʻole o ke ao i ke ao. He kala ʻole ia i melemele loa i ke kala. Inā he discolored, cloudy, a i ʻole nā ​​ʻāpana paʻa i ka wai, mai hoʻohana. Inā pono, e kāhea i kāu kauka e pili ana i ka loaʻa ʻana o kahi hou. Eia kekahi, e nānā i ka lā palena pau i ka hāmeʻa e hōʻoia i ka pau ʻole o ka lāʻau.
• Ma hope o ka holoi ʻana i kou mau lima me ke kopa a me ka wai, koho i kahi pūnaewele injection. Aimovig hiki ke injected ma kēia mau wahi:
• kou ʻōpū (ma ka liʻiliʻi he 2 ʻīniha mai kou pihi ʻōpū)
• ʻo ka mua o kou mau ʻūhā (ma ka liʻiliʻi he 2 ʻīniha ma luna o kou kuli a i ʻole 2 ʻīniha ma lalo o kou ʻūlū)
• ke kua o kou mau lima kiʻekiʻe (inā hāʻawi kekahi iā ʻoe i ka injection)
• E hoʻohana i kahi holoi waiʻona e hoʻomaʻemaʻe i kahi āu e hoʻolālā ai e hoʻopili. E hoʻomaloʻo loa i ka waiʻona ma mua o kou hoʻopili ʻana i ka lāʻau.
• Mai hoʻokomo iā Aimovig i kahi ʻili i pākī, paʻakikī, ʻulaʻula, a palupalu paha.

Ke hoʻohana nei i ka autoinjector

1. Huki i ka pāpale keʻokeʻo pololei mai ka autoinjector. Hana i kēia ma mua o ʻelima mau minuke ma mua o kou hoʻohana ʻana i ka hāmeʻa.
2. E kīloi a pinch paha i kahi o ka ʻili kahi āu e hoʻolālā ai e hoʻopili i ka lāʻau. E hana i kahi paʻa o ka ʻili e pili ana i 2 ʻīniha ka laulā no kāu pahu kui.
3. E kau i ka autoinjector ma kou ʻili ma ke kihi 90 degere. E kaomi ikaika i lalo i kou ʻili a hiki i ka wā e hele ai.
4. Kaomi i ka pihi hoʻomaka poni ma ka piko o ka autoinjector a lohe ʻoe i kahi kaomi.
5. E hoʻokuʻu i ka pihi hoʻomaka poni akā hoʻomau i ka paʻa ʻana o ka autoinjector i lalo i kou ʻili a hiki i ka puka window ma ka autoinjector e melemele. Lohe a lohe paha ʻoe i kahi "kaomi." Hiki iā kēia ke piʻi i 15 kekona. He mea nui e hana i kēia kaʻina e hōʻoia i loaʻa iā ʻoe ka lāʻau āpau.
6. Wehe i ka autoinjector mai kou ʻili a hoʻolei aku i kāu ipu hoʻolei sharps.
7. Inā he koko ma ka pūnaewele injection, kaomi i ka pōpō pulupulu a i ʻole ka ʻeke ma luna o ka ʻili, akā mai ʻānai. E hoʻohana i kahi kāʻei hoʻopili inā pono.
8. Inā 140 mg kāu kau ma kēlā me kēia mahina, e hana hou i kēia mau hana me ka autoinjector lua. Mai hoʻohana i ka pūnaewele hoʻopunipuni like me ke kuikahi mua.

Manawa

Lawe ʻia ʻo Aimovig i hoʻokahi manawa i kēlā me kēia mahina. Hiki ke lawe ʻia i kēlā me kēia manawa o ka lā.

Inā haʻalele ʻoe i kahi lāʻau, lawe iā Aimovig ke hoʻomanaʻo koke ʻoe. ʻO ka mahele hope aʻe he hoʻokahi mahina ma hope o kou lawe i kēlā. ʻO ka hoʻohana ʻana i kahi mea hana hoʻomanaʻo lāʻau hiki ke kōkua iā ʻoe e hoʻomanaʻo e lawe iā Aimovig ma ka papa kuhikuhi.

Lawe iā Aimovig me ka meaʻai

Hiki ke kiʻi ʻia ʻo Aimovig me ka ʻole o ka meaʻai.

Waihona

Pono e mālama ʻia ʻo Aimovig i loko o ka pahu hau. Hiki ke lawe ʻia i waho o ka pahu hau akā pono e hoʻohana i loko o ʻehiku mau lā. Mai hoʻihoʻi iā ia i loko o ka pahu hau ke lawe ʻia i waho a lawe ʻia i ka mahana wela.

Mai hoʻopili iā ʻAimovig. Eia kekahi, e mālama iā ia i loko o kāna pūʻolo mua e pale aku iā ia mai ka mālamalama.

Pehea e hana ai ʻo Aimovig

ʻO Aimovig kahi lāʻau i kapa ʻia he monoclonal antibody. Hana ʻia kēia ʻano lāʻau i loko o kahi lab mai nā protein immune system. Hana ʻo Aimovig ma ka hoʻōki ʻana i ka hana o kahi protein i loko o kou kino i kapa ʻia ʻo ka peptide pili i ka ʻenekene kalona (CGRP). Hiki i ka CGRP ke hana i ka mumū a me ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) i kou lolo.

ʻO ka mumū a me ka vasodilation i lawe ʻia mai e CGRP kahi kumu kūpono o ka ulu ʻana o ka migraine. I ka ʻoiaʻiʻo, ke hoʻomaka nei kahi ʻeha migraine e hoʻomaka, loaʻa i nā kānaka nā kiʻekiʻe kiʻekiʻe o ka CGRP i ko lākou kahe koko. Kōkua ʻo Aimovig i ka pale ʻana i ka migraine ma ka hoʻōki ʻana i ka hana o CGRP.

ʻOiai ka hapanui o nā lāʻau e hana i ka hoʻopili ʻana i nā mea he nui i kou kino, hana nā monoclonal antibodies e like me Aimovig ma hoʻokahi protein i loko o ke kino. Ma muli o kēia, hiki i ka Aimovig ke hōʻemi i nā launa lāʻau a me nā hopena ʻē aʻe. Hiki i kēia ke hana i kahi koho lapaʻau maikaʻi no ka poʻe hiki ʻole ke lawe i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole nā ​​pilina.

ʻO Aimovig paha kahi koho lapaʻau maikaʻi no ka poʻe i loaʻa ʻole kahi lāʻau ʻē aʻe e hiki ai ke hōʻemi i ko lākou mau lā migraine.

Pehea ka lōʻihi o ka hana?

Ma hope o kou hoʻomaka ʻana e lawe iā Aimovig, e hala paha i mau pule e ʻike ai i ka hoʻomaikaʻi ʻana i kāu maʻi migraine. E holo pono paha ʻo Aimovig ma hope o kekahi mau mahina.

He nui ka poʻe i lawe iā Aimovig i ka wā o nā hoʻokolohua hoʻokolohua i loaʻa nā lā liʻiliʻi o ka migraine i loko o hoʻokahi mahina o ka hoʻomaka ʻana o ka lāʻau. Loaʻa ka liʻiliʻi o nā lā o ka migraine i ka poʻe ma hope o ka hoʻomau ʻana i ka mālama ʻana i kekahi mau mahina.

ʻO Aimovig a me ka hāpai keiki

ʻAʻole lawa nā noiʻi i hana ʻia e ʻike inā palekana ʻo Aimovig e lawe i ka wā hāpai. ʻAʻole hōʻike nā haʻawina holoholona i kekahi pilikia i ka hāpai keiki ke hāʻawi ʻia ʻo Aimovig i kahi wahine hāpai. Eia naʻe, ʻaʻole wānana pinepine nā noiʻi holoholona inā e palekana nā lāʻau i nā kānaka.

Inā hāpai ʻoe a noʻonoʻo paha i ka hāpai ʻana, e kamaʻilio me kāu kauka e ʻike inā kūpono ʻo Aimovig iā ʻoe. Pono ʻoe e kali a hiki i kou hāpai ʻole ʻana e hoʻohana iā Aimovig.

ʻO Aimovig a me ka hānai ʻana i ka waiū

ʻAʻole ʻike ʻia inā hele ʻo Aimovig i ka waiū umauma. No laila, ʻaʻole maopopo inā palekana ʻo Aimovig e hoʻohana i ka wā e hānai ana i ka waiū.

Inā ʻoe e noʻonoʻo i ka hoʻomaʻamaʻa ʻana me Aimovig ʻoiai ʻoe e hānai ana i kāu keiki, e kamaʻilio me kāu kauka e pili ana i nā pono a me nā pilikia. Pono paha ʻoe e hōʻoki i ka hānai ʻana inā hoʻomaka ʻoe e lawe iā Aimovig.

Nā nīnau e pili ana iā Aimovig

Eia nā pane i kekahi o nā nīnau e nīnau pinepine ʻia e pili ana iā Aimovig.

ʻO ke kū ʻana iā Aimovig ke kumu o ka haʻalele ʻana?

ʻAʻohe lono o ka hopena hope ʻana ma hope o ke kū ʻana iā Aimovig. Eia nō naʻe, ʻae ʻia ʻo Aimovig e ka FDA, i ka makahiki 2018. ʻO ka helu o ka poʻe i hoʻohana a kū hoʻi i ka Aimovig therapy e kaupalena ʻia.

He biologic ʻo ʻAimovig?

Ae. ʻO Aimovig kahi antibody monoclonal, kahi ʻano biologic. ʻO kahi biologic kahi lāʻau i hoʻomohala ʻia mai nā mea olaola, ma mua o nā kemikolo.

Ma muli o ka launa pū ʻana me nā pūnaewele immune kikoʻī kikoʻī a me nā protein, manaʻo ʻia nā biologics e like me Aimovig e loaʻa nā hopena ʻē aʻe i ka hoʻohālikelike ʻia me nā lāʻau e hoʻopili i ka laulā o nā ʻōnaehana kino, e like me nā lāʻau migraine ʻē aʻe.

Hiki iā ʻoe ke hoʻohana iā Aimovig e mālama i ka migraine?

ʻAʻole hoʻohana ʻia ʻo Aimovig e pale i ka ʻeha o ka migraine ma mua o ka hoʻomaka ʻana. ʻAʻole ia e hana e mālama i ka migraine i hoʻomaka mua.

Hoʻoponopono ʻo Aimovig i ka migraine?

ʻAʻole, ʻaʻole hoʻōla ʻo Aimovig iā migraine. ʻAʻole loaʻa nā lāʻau i kēia manawa e hōʻola i ka migraine.

Pehea ʻokoʻa ʻo Aimovig mai nā lāʻau migraine ʻē aʻe?

He ʻokoʻa ʻo Aimovig mai ka hapanui o nā lāʻau migraine ʻē aʻe no ka mea ʻo ia ka lāʻau lapaʻau mua i ʻae ʻia e FDA i hana kūikawā ʻia e pale aku ai i ka ʻeha o ka migraine. ʻO Aimovig kahi ʻāpana o kahi papa hou o nā lāʻau i kapa ʻia he antagonists peptide (CGRP) e pili ana i ka ʻenekia.

ʻO ka hapa nui o nā lāʻau ʻē aʻe i hoʻohana ʻia e pale aku ai i ka ʻeha o ka migraine i hoʻomohala maoli ʻia no nā kumu ʻē aʻe, e like me ka mālama ʻana i ka hopu ʻana, ke koko kiʻekiʻe, a me ke kaumaha. Hoʻohana ʻia ka hapa nui o kēia mau lāʻau i ka lepili e pale aku ai i ka ʻeha o ka migraine.

ʻO ka hoʻokomo ʻana i kēlā me kēia mahina ka mea ʻokoʻa iā Aimovig mai ka hapanui o nā lāʻau lapaʻau pale migraine. ʻO ka hapa nui o kēia mau lāʻau ʻē aʻe i hele mai ma ke ʻano he papa a i ʻole nā ​​pila. ʻO Botox kahi lāʻau i koho ʻia e hele mai ma ke ʻano he injection. Eia naʻe, pono e hāʻawi ʻia i ke keʻena o ke kauka i hoʻokahi manawa i kēlā me kēia ʻekolu mahina. Hiki iā ʻoe ke hāʻawi iā ʻoe iho i nā injection o Aimovig ma ka home.

A ʻaʻole like me ka nui o nā lāʻau lapaʻau migraine ʻē aʻe, ʻo Aimovig kahi maʻi pale monoclonal. ʻO kēia kahi ʻano lāʻau i hoʻomohala ʻia i kahi lab. Hana ʻia ia mai nā pūnaewele ʻōnaehana pale.

Wāwahi ʻia nā meaola monoclonal i loko o nā huna like ʻole i loko o ke kino. Uhaʻi ʻia nā lāʻau lapaʻau ʻē aʻe e ka ate. Ma muli o kēia ʻokoʻa, loaʻa i nā antibodies monoclonal e like me Aimovig ka liʻiliʻi o ka launa lāʻau ma mua o nā lāʻau ʻē aʻe i hoʻohana ʻia e pale aku i ka ʻeha o ka migraine.

Inā lawe au iā Aimovig, hiki iaʻu ke hōʻoki i ka lawe ʻana i kaʻu mau lāʻau pale ʻē aʻe?

Malia paha. E pane ʻokoʻa ke kino o kēlā me kēia kanaka iā Aimovig. Inā hōʻemi ʻo Aimovig i ka nui o nā maʻi migraine i loaʻa iā ʻoe, hiki paha iā ʻoe ke hōʻoki i ka lawe ʻana i nā lāʻau pale ʻē aʻe. Akā ke hoʻomaka mua ʻoe i ka lāʻau, e paipai paha kāu kauka e hoʻomaka ʻoe e lawe iā Aimovig me nā lāʻau lapaʻau ʻē aʻe.

Ma hope o kou lawe ʻana iā Aimovig no ʻelua a ʻekolu paha mahina, e kamaʻilio pū kāu kauka me ʻoe e pili ana i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe. Hiki iā ʻoe a me kāu kauka ke kūkākūkā e pili ana i ka hoʻōki ʻana i nā lāʻau pale ʻē aʻe āu e lawe ai a i ʻole hoʻemi ʻia ana i kāu lāʻau o kēia mau lāʻau.

Hoʻopiʻi over Aimovig

Ke hoʻokomo nei i nā kaha he nui o Aimovig hiki ke hoʻonui i kou makaʻu i nā hopena o ke kahua o ka injection. Inā maʻi ʻoe a hypersensitive paha iā Aimovig a i ʻole ka latex (kahi mea hana i ka ʻūlū o Aimovig), e makaʻu paha ʻoe no kahi hopena ʻoi loa.

Nā hōʻailona overdose

Hiki i nā ʻōuli o ka overdose ke komo pū me:

• ʻeha ʻeha, ʻili, a ʻulaʻula paha i kahi e kokoke ana i ka injection
• ʻōpala
• hives
• angioedema (ʻōhū ma lalo o ka ʻili)
• pehu o ka elelo, ka puʻu, a waha paha
• pilikia hanu

He aha e hana ai inā he overdose

Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau, e kāhea i kāu kauka a i ʻole e ʻimi i ke alakaʻi mai ka ʻAmelika Hui Pū ʻIa Poison Control ma 800-222-1222 a i ʻole ma o kā lākou mea pono pūnaewele. Akā inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele koke i kahi lumi pilikia kokoke.

Nā ʻōlelo aʻoaʻo Aimovig

Ma mua o ka lawe ʻana iā Aimovig, e kamaʻilio me kāu kauka e pili ana i kāu mōʻaukala olakino. ʻAʻole kūpono paha ʻo Aimovig iā ʻoe inā loaʻa iā ʻoe kekahi ʻano olakino. Pākuʻi ʻia kēia mau mea:

• Pākuʻi Latex. Loaʻa i ka Aimovig autoinjector kahi ʻano o ke kāpili e like me ka latex. Hiki paha i kēia ke hopena i ka hopena i nā poʻe āpau i ka hopena. Inā loaʻa iā ʻoe kahi moʻolelo o nā hopena koʻikoʻi i nā huahana i loaʻa ka hopena, ʻaʻole paha ʻo Aimovig ka lāʻau kūpono no ʻoe.

Pau ʻo Aimovig a me kahi waiho

Ke haʻalele ʻia ʻo Aimovig mai ka hale kūʻai lāʻau, e hoʻohui ka kauka i kahi lā palena pau i ka lepili ma ka ʻōmole. ʻO kēia lā maʻamau hoʻokahi makahiki mai ka lā i hāʻawi ʻia ai ka lāʻau.

ʻO ke kumu o kēlā mau lā palena pau e hōʻoia i ka hopena o nā lāʻau i kēia manawa. ʻO ke kūlana o ka Food and Drug Administration (FDA) i kēia manawa e hōʻalo i ka hoʻohana ʻana i nā lāʻau i make.

Pehea ka lōʻihi o ka maikaʻi o ka lāʻau e hiki ai ke hilinaʻi i nā kumu he nui, me ke ʻano a me kahi e mālama ʻia ai ka lāʻau.

E mālama pono ʻo Aimovig i ka autoinjector prefilled i loko o ka pahu hau. Hiki ke mālama ʻia ma waho o ka pahu hau a ʻehiku mau lā. Mai hoʻihoʻi i loko o ka pahu hau ke hiki i ka mahana wela.

Mai hoʻoluliluli a paʻa hau paha i ka Aimovig autoinjector. A mālama i ka autoinjector i loko o ka pahuhoho kumu e pale iā ia mai ka mālamalama.

Inā loaʻa iā ʻoe kahi lāʻau i hoʻohana ʻole ʻia i hala i ka lā palena pau, e kamaʻilio me kāu kauka lāʻau e pili ana inā hiki paha iā ʻoe ke hoʻohana.

ʻO ka ʻike ʻoihana no Aimovig

Hāʻawi ʻia ka ʻike aʻe no nā kauka lapaʻau a me nā ʻoihana ola.

Mekanism o ka hana

ʻO Aimovig (erenumab) kahi kanaka monoclonal antibody e hoʻopili ana i ka helu helu e pili ana i ka peptide (CGRP) e pili ana i ka genon a me ka pale ʻana i ka ligand CGRP mai ka hoʻoulu ʻana i ka mea loaʻa.

Pharmacokinetics a me ka metabolism

Mālama ʻia ʻo Aimovig i kēlā me kēia mahina a hiki i nā paʻa paʻa paʻa ma hope o ʻekolu mau kau. Loaʻa ka noʻonoʻo nui i nā lā ʻeono. ʻAʻole kū ka Metabolism ma o nā ala cytochrome P450.

Hoʻopili ka hoʻopaʻa ʻana i ka CGRP a hoʻokuke i ka hoʻopau ma nā haʻahaʻa haʻahaʻa. Ma nā kiʻekiʻe kiʻekiʻe, hoʻopau ʻia ʻo Aimovig ma o nā ala proteolytic nonspecific. ʻAʻole manaʻo ʻia ka hōʻino ʻana o ka hōʻino a me ka maʻi hepatic paha i nā waiwai ʻoihana lāʻau lapaʻau.

Nā Kūʻai Kūʻai

ʻAʻohe contraindications i ka hoʻohana Aimovig.

Waihona

E mālama pono ʻo Aimovig i ka autoinjector prefilled i loko o ka pahu hau i kahi mahana ma waena o 36⁰F a me 46⁰F (2⁰C a me 8⁰C). Lawe ʻia paha ia mai ka pahu hau a mālama ʻia i ke ana wela o ka lumi (a i 77⁰F, a i ʻole 25⁰C) no 7 mau lā.

E mālama iā Aimovig i loko o ka pōpō kumu e pale aku ai iā ia mai ka mālamalama. Mai hoʻihoʻi iā ia i loko o ka pahu hau ke hiki mai ka mahana wela. Mai hoʻopili a hoʻoluliluli hoʻi i ka Aimovig autoinjector.

Hoʻolaha: Ua hana ʻo Nūhou Lapaʻau i kēia mau lā e hōʻoia i ka pololei, ka laulā, a me ka lā hou o nā ʻike āpau. Eia nō naʻe, ʻaʻole pono e hoʻohana i kēia ʻatikala i pani no ka ʻike a me ka mākaukau o kahi loea mālama ola laikini. E nīnau mau ʻoe i kāu kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka lawe ʻana i nā lāʻau. Hiki ke loli i ka ʻike o ka lāʻau i loko a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana a pau, nā kuhikuhi, ka mālama ʻana, nā ʻōlelo aʻoaʻo, nā launa lāʻau, nā hopena maʻi ʻaʻai, a me nā hopena maikaʻi ʻole. ʻO ka loaʻa ʻole o nā ʻōlelo aʻoaʻo a i ʻole nā ​​ʻike ʻē aʻe no kahi lāʻau i hāʻawi ʻia ʻaʻole ia e hōʻike i ka palekana o ka lāʻau a lāʻau paha i kūpono no nā mea maʻi āpau a i ʻole nā ​​hoʻohana kikoʻī āpau.