Mea Kākau: Janice Evans
Lā O Ka Hana: 2 Iulai 2021
HōʻAno Hou I Ka Lā: 15 Nowemapa 2024
Anonim
A Molecular View of HIV Therapy
Wikiō: A Molecular View of HIV Therapy

Anter

Hoʻohana ʻia ʻo Saquinavir i hui pū ʻia me ritonavir (Norvir) a me nā lāʻau ʻē aʻe e mālama ai i ka maʻi maʻi maʻi maʻi (HIV). Aia ʻo Saquinavir i kahi papa o nā lāʻau i kapa ʻia nā protease inhibitors. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi HIV i loko o ke koko. ʻOiai ʻaʻole ʻo ka saquinavir e hoʻōla i ka maʻi HIV, hiki iā ia ke hōʻemi i kou manawa o ka hoʻomohala ʻia ʻana o ka maʻi maʻi maʻi (AIDS) a me nā maʻi e pili ana i ka maʻi HIV e like me nā maʻi ʻino a i ʻole ka maʻi ʻaʻai. ʻO ka lawe ʻana i kēia mau lāʻau me ka hana palekana ʻana i ka moekolohe a me ka hoʻololi ʻana i nā ʻano nohona ʻē aʻe e hōʻemi paha i ka lawe ʻana i ka maʻi HIV i kekahi poʻe ʻē aʻe.

Hele mai ʻo Saquinavir ma ke ʻano he capsule a me kahi papa e lawe ʻia e ka waha. Lawe ʻia ia i ka manawa like me ritonavir (Norvir) ʻelua mau manawa i ka lā ma waena o 2 mau hola ma hope o ka pāʻina piha. E maʻalahi paha e hoʻomanaʻo e lawe i ka saquinavir inā ʻoe e lawe me nā ʻai. E lawe i ka saquinavir ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pono i ka saquinavir. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


E ale i nā papa holoʻokoʻa; mai nau, a naʻu hoʻi.

Inā ʻaʻole hiki iā ʻoe ke ale i ka capsule holoʻokoʻa, hiki iā ʻoe ke lawe i ka saquinavir ma ka wehe ʻana i ka capsule a hoʻohuihui i nā mea me ka syrup syrup, sorbitol, a me jam. E hoʻomākaukau i kēlā me kēia mahele lāʻau, e hoʻohui i nā teaspoon he 3 (15 ml) o ka syrup kō, sorbitol, a i ʻole jam i kahi ipu hakahaka. E wehe i ka capsule saquinavir a hoʻohui i nā ʻike i ka ipu. E hoʻoulu i ka hui no 30 a 60 kekona. Inā ʻoe i hoʻohana i ke syrup anuanu, sorbitol, a i ʻole jam, e kali no ka hiki mai o ka hoʻohuihui i ka mahana o ka lumi ma mua o ka ʻai ʻana. E ʻai pono i ka hui holoʻokoʻa i loaʻa iā ʻoe ka piha piha.

E hoʻomau i ka lawe ʻana i ka saquinavir ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka saquinavir me ke kamaʻilio ʻole ʻana me kāu kauka. Inā ʻaʻole ʻoe e nalo i nā lāʻau, lawe i ka mea liʻiliʻi ma mua o ka lāʻau i kauoha ʻia a i ʻole e hōʻoki i ka lawe ʻana i ka saquinavir, e ʻoi aku ka paʻakikī o kou ʻano e mālama.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ka saquinavir a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.


Hoʻohana ʻia ʻo Saquinavir i kekahi manawa me ritonavir (Norvir) a me nā lāʻau ʻē aʻe e kōkua ai i ka pale ʻana i ka maʻi i nā limahana limahana a i ʻole nā ​​kānaka ʻē aʻe i pili i ka maʻi HIV. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i kēia lāʻau no kou maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka saquinavir,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka saquinavir, nā lāʻau ʻē aʻe, lactose, a i ʻole kekahi o nā mea hana ʻē aʻe i nā capsule saquinavir a i ʻole nā ​​papa. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka saquinavir. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe i kekahi o nā lāʻau aʻe: alfuzosin (Uroxatral); atazanavir (Reyataz, i Evotaz); clarithromycin (Biaxin, i Prevpac); clozapine (Clozaril, Fazaclo, Versacloz); dasatinib (Sprycel); nā lāʻau lapaʻau ergot e like me dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Ergomar, ma Cafergot, ma Migergot, a me nā mea ʻē aʻe), a me methylergonovine (Methergine); erythromycin (E.E.S., E-mycin, Erythrocin, nā mea ʻē aʻe); halofantrine; haloperidol (Haldol); kekahi mau lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), tutupocaine (Xylocaine), propafenone (Rhythmol), a me quinidine (i Nuedexta); lovastatin (Altoprev); lurasidone (Latuda); nā lāʻau no ka maʻi noʻonoʻo a me ka nausea e like me chlorpromazine, a me thioridazine; ma ka waha ka midazolam; pentamidine (Nebupent, Pentam); pimozide (Orap); quinine (Qualaquin); rifampin (Rifadin, Rimactane, ma Rifamate, Rifater); sildenafil (ʻo ka inoa Revatio wale nō i hoʻohana ʻia no ka maʻi puʻupuʻu); simvastatin (Zocor, Flolopid, i Vytorin); sunatinib (Sutent); tacrolimus (Astagraf XL, Envarsus XR, Prograf); trazodone; triazolam (Halcion); aiʻole ziprasidone (Geodon). E haʻi pū aku i kāu kauka a kauka paha inā ʻoe e lawe ana i ka rilpivirine (Edurant, ma Juluca, Odefsey, Complera) a i ʻole inā ua oki ʻoe i ka lawe ʻana i loko o nā pule ʻelua i hala. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka saquinavir inā ʻoe e lawe i hoʻokahi aʻoi aku paha o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E hōʻoia e haʻi i kekahi o kēia mau mea: anticoagulants ('nā mea hōʻemi koko') e like me warfarin (Coumadin, Jantoven); nā antifungals e like me itraconazole (Onmel, Sporanox) a me ketoconazole benzodiazepines e like me alprazolam (Xanax), clorazepate (Gen-Xene, Tranxene), diazepam (Diastat, Valium), a me flurazepam; beta blockers e like me atenolol (Tenormin, ma Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, ma Dutoprol, ma Loressor HCT), nadolol (Corgard, ma Corzide), a me propranolol (Hemangeol, Inderal, Innopran); bosentan (Tracleer); calcium blockers blockers e like me amlodipine (Norvasc, ma Caduet, Lotrel, a me nā mea ʻē aʻe), diltiazem (Cardizem, Cartia, Tiazac, a me nā mea ʻē aʻe), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), nimodipine (Nymalize ), nisoldipine (Sular), a me verapamil (Calan, Verelan, ma Tarka); kekahi mau lāʻau hoʻohaʻahaʻa kolesterol (statins) e like me atorvastatin (Lipitor, ma Caduet); cobicistat (Tybost, ma Evotaz, Genvoya, Prezcobix, a me Stribild); corticosteroids e like me betamethasone, budesonide (Entocort, Pulmicort, Uceris, ma Symbicort), cicleonide (Alvesco, Zetonna, Omnaris), dexamethasone, fluticasone (Arnuity Ellipta, Flonase, Flovent, i Advair, kekahi), methylprednisone ), prednisone (Rayos), a me triamcinolone (Kenalog); colchisin (Colcrys, Mitigare); digoxin (Lanoxin); fentanyl (Abstral, Actiq, Duragesic, nā mea ʻē aʻe); kekahi mau immunosuppressants e like me cyclosporine (Gengraf, Neoral, Sandimmune), a me sirolimus (Rapamune); nā lāʻau e mālama ai i ka maʻi HIV a i ʻole ka maʻi AIDS me indinavir (Crixivan), lopinavir me ritonavir (Kaletra), maraviroc (Selzentry), nelfinavir (Viracept), a i ʻole tipranavir me ritonavir (Aptivus); kekahi mau lāʻau no ka puʻuwai kūlike ʻole e like me ibutilide (Corvert), a me sotalol (Betapace, Sorine, Sotylize); nā lāʻau e mālama ai i ka hopu ʻana e like me ka carbamazepine (Carbatrol, Epitol, Tegretol, a me nā mea ʻē aʻe), phenytoin (Dilantin, Phenytek), a me phenobarbital; methadone (Dolophine, Methadose); nefazodone; omeprazole (Prilosec, i Yosprela, Zegerid); kekahi mau mea hoʻopale ph phodiodiesterase (PDE5) e like me sildenafil (Viagra), tadalafil (Adcirca, Cialis), a me vardenafil (Levitra, Staxyn); quetiapine (Seroquel); quinupristin a me dalfopristin (Synercid); rifabutin (Mycobutin); salmeterol (Serevent, ma Advair); a me kekahi antidepressants tricyclic me amitriptyline, clomipramine (Anafranil), imipramine (Surmontil, Tofranil), a me ka maprotiline. E launa pū paha nā lāʻau ʻē aʻe me ka saquinavir, no laila e ʻike pono i kāu kauka a me ka kauka lāʻau e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe, ʻo ia hoʻi ʻo St. John's wort, a me nā capsules kālika.
  • e haʻi i kāu kauka inā inu ʻoe a ua inu paha i ka nui o ka wai ʻona, a inā ʻo ʻoe a ʻo kekahi paha o kou ʻohana ua loaʻa a loaʻa paha i ka maʻi diabetes. E haʻi pū aku i kāu kauka inā loaʻa a i ʻole loaʻa paha iā ʻoe kahi puʻuwai kūlike ʻole, ke kiʻekiʻe o ke kolesterol a i ʻole nā ​​triglycerides (nā momona i loko o ke koko); hemophilia (kahi maʻi koko); ʻaʻole hiki i ke kino ke hana i ka nui o ka lactase a i ʻole hiki ke ʻae i ka lactose, a i ʻole ka maʻi puʻuwai a i ʻole nā ​​puʻupaʻa.
  • e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Inā hāpai ʻoe i ka lawe ʻana i ka saquinavir, e kāhea i kāu kauka. ʻAʻole pono ʻoe e hānai waiū inā loaʻa ʻoe i ka maʻi HIV a i ʻole ke lawe nei ʻoe i ka saquinavir.
  • pono ʻoe e ʻike he hiki i ka saquinavir ke hoʻemi i ka pono o nā mea pale hormonal (nā lāʻau kaohi hānau, nā pā, nā apo, a i ʻole nā ​​ʻoki ʻana). E kamaʻilio me kāu kauka e pili ana i ka hoʻohana ʻana i kahi ʻano o ka kaohi hānau.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka saquinavir.
  • e hoʻomaopopo ʻoe i ka momona o kou kino e hoʻonui a neʻe paha i nā wahi like ʻole o kou kino, e like me kou kua i luna, ʻāʻī ('' buffalo hump ''), nā umauma, a puni kou ʻōpū. ʻIke paha ʻoe i ka nalo ʻana o ka momona o ke kino mai kou alo, mau wāwae, a me kou mau lima.
  • pono ʻoe e ʻike e ʻike paha ʻoe i ka hyperglycemia (hoʻonui i kāu kō kō) ʻoiai ʻoe e lawe nei i kēia lāʻau, ʻoiai inā ʻaʻohe ou diabetes. E haʻi koke i kāu kauka inā loaʻa iā ʻoe kekahi o nā ʻōuli aʻe ke lawe nei ʻoe i ka saquinavir: make wai loa, mimiki pinepine, pololi nui, ʻike maka ʻole ʻia, a nāwaliwali paha. He mea nui ia e kāhea aku i kāu kauka ke loaʻa koke iā ʻoe kekahi o kēia mau ʻōuli, no ka mea, ʻaʻole mālama ʻia ke kō koko kiʻekiʻe e mālama ʻia ai i kahi ʻano koʻikoʻi i kapa ʻia ʻo ketoacidosis. Lilo paha ʻo Ketoacidosis i mea hoʻoweliweli i ke ola ke mālama ʻole ʻia ia i ka wā mua. ʻO nā ʻōuli o ketoacidosis e komo pū me ka waha maloʻo, kahe a me ka luaʻi, ka hanu o ka hanu, ka hanu e ʻaʻala i ka hua, a me ka emi o ka ʻike.
  • pono ʻoe e ʻike ʻoiai ʻoe e lawe nei i nā lāʻau e mālama ai i ka maʻi HIV, e ikaika paha kāu ʻōnaehana pale a hoʻomaka e hakakā i nā maʻi ʻē aʻe i hala i kou kino a i ʻole e hana i nā hanana ʻē aʻe. Hiki iā ʻoe ke hoʻomohala i nā ʻōuli o kēlā mau maʻi a i ʻole nā ​​kūlana. Inā loaʻa iā ʻoe nā hōʻailona hou a pōʻino paha ma hope o ka hoʻomaka ʻana o ka mālama ʻana me ka saquinavir, e haʻi pono i kāu kauka.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻōlau a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i kēia lāʻau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Saquinavir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • pāhoehoe
  • ʻeha ka ʻōpū
  • nausea
  • ka luaʻi
  • kōpaʻa
  • luhi
  • ʻeha kua
  • nā lehelehe maloʻo a ʻili paha
  • fiva

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • ʻehu, ʻili, ʻōhuʻu o nā maka, ka maka, waha, ʻāʻī, a me nā lehelehe, paʻakikī i ka hanu ʻana a me ka ale ʻana
  • ʻili a ʻiliʻili paha
  • melemele o ka ʻili a i ʻole nā ​​maka, nalo ka makemake ʻole, ka maʻi palū e like me nā ʻōuli, ka luhi nui loa, ka mimi ʻeleʻele, nā noho ʻāpana māmā, ka ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
  • dizziness, lightheadedness, lohi, kūlike ʻole, a i ʻole kuʻi ka puʻuwai puʻuwai, maʻule

Hoʻokumu paha ʻo Saquinavir i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau ke lawe nei ʻoe i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • ʻeha puʻu

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab a ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i ka saquinavir. Hiki paha i kāu kauka ke kauoha i kahi electrocardiogram (ECG; hoʻāʻo e ana i ka hana uila i ka puʻuwai) ma mua a i kāu wā e lapaʻau ai.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Hoʻokipa®
Nānā Hou - 06/15/2019

Nā Pou Hou

He aha ka Oedipus Complex

He aha ka Oedipus Complex

ʻO ka hui ʻo Oedipu kahi manaʻo i pale ʻia e ka p ychoanaly t igmund Freud, ka mea e pili ana i kahi pae o ka hoʻomohala p ycho exual o ke keiki, i kapa ʻia ʻo ka phallic pha e, kahi i hoʻomaka ai ʻo ...
ʻO ka anemia hemahema hao: he aha ia, nā ʻōuli a me nā lāʻau

ʻO ka anemia hemahema hao: he aha ia, nā ʻōuli a me nā lāʻau

ʻO ka anemia hemahema hao kekahi ʻano anemia e kū ana ma muli o ka nele o ka hao i loko o ke kino, kahi e hoʻemi ai i ka nui o ka hemoglobin a, no laila, nā hunaola ʻulaʻula, ʻo ia nā hunaola ke kulea...