Mea Kākau: Janice Evans
Lā O Ka Hana: 23 Iulai 2021
HōʻAno Hou I Ka Lā: 18 Nowemapa 2024
Anonim
USMLE: Medical Video Lectures Pharmacology about Gemfibrozil by UsmleTeam
Wikiō: USMLE: Medical Video Lectures Pharmacology about Gemfibrozil by UsmleTeam

Anter

Hoʻohana ʻia ʻo Gemfibrozil me nā loli o ka papaʻai (kaohi ʻana o ka cholesterol a me ka lawe ʻana i ka momona) e hōʻemi i ka nui o ke kolukol a me nā triglycerides (nā mea momona ʻē aʻe) i ke koko i kekahi poʻe me nā triglycerides kiʻekiʻe loa e makaʻu i ka maʻi pancreatic (nā kūlana e hoʻopili ana i ka pancreas, kahi gland e hana i ka wai e wāwahi i ka meaʻai a me nā hormones e kāohi i ke kō kō. Hoʻohana pū ʻia ʻo Gemfibrozil i ka poʻe me ka hoʻohuihui o nā lipoprotein haʻahaʻa kiʻekiʻe (HDL; 'maikaʻi kolesterol') a me nā lipoprotein haʻahaʻa haʻahaʻa (LDL; 'maikaʻi kolesterol') a me nā pae triglyceride e hōʻemi i ka pilikia o ka maʻi puʻuwai. Aia ʻo Gemfibrozil i kahi papa o nā lāʻau lapaʻau lipid-regulating i kapa ʻia fibrates. Hana ia ma ka hoʻemi ʻana i ka hana o nā triglycerides i ke ake.

Hele mai ʻo Gemfibrozil ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i ʻelua mau manawa i ka lā, 30 mau minuke ma mua o ka ʻaina kakahiaka a me ke ahiahi. Lawe iā gemfibrozil ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i gemfibrozil e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


Mālama ʻo Gemfibrozil i nā triglycerides kiʻekiʻe a me HDL haʻahaʻa, akā ʻaʻole ia e hoʻōla iā lākou. E hoʻomau i ka lawe gemfibrozil ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i gemfibrozil me ka ʻole o ke kamaʻilio ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i gemfibrozil,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka gemfibrozil, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa gemfibrozil. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe i dasabuvir (i Viekira Pak), simvastatin (Zocor, i Vytorin), a i ʻole repaglinide (Prandin, i Prandimet). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka gemfibrozil ʻoiai ke lawe nei i kekahi o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E haʻi pono i kekahi o kēia mau mea: atorvastatin (Lipitor, ma Caduet), bosentan (Tracleer), colchisin (Colcrys, Mitigare, ma Col-Probenecid), dabrafenib (Tafinlar), enzalutamide (Xtandi), ezetimibe (Zetia, ma Vytorin ), fluvastatin (Lescol), glyburide (Diabeta, Glynase, in Glucovance), irinotecan (Camptosar, Onivyde), loperamide (Imodium), lovastatin (Altoprev), montelukast (Singulair), olmesartan (Benicar, in Azor, Tribenzor) (Abraxane, Taxol), pioglitazone (Actos, ma Actoplus Met, Duetact, Oseni), pitavastatin (Livalo), pravastatin (Pravachol), rifampin (Rifadin, Rimactane, ma Rifamate, Rifater), rosiglitazone (Avandia), rosuvastatin , valsartan (Diovan, ma Entresto, Exforge), a me warfarin (Coumadin, Jantoven). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. E launa pū paha nā lāʻau ʻē aʻe me gemfibrozil, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • inā ʻoe e lawe i ka colestipol (Colestid), e lawe i kēia lāʻau i 2 mau hola ma mua a i ʻole 2 mau hola ma hope o gemfibrozil.
  • e haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi puʻuwai, ate, a i ʻole ka maʻi o ka gallbladder. E haʻi paha kāu kauka iā ʻoe mai lawe i ka gemfibrozil.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i gemfibrozil, e kāhea i kāu kauka.

ʻAi i kahi papaʻai momona momona, momona momona. E mālama pono i nā hana hoʻoikaika kino a me nā papa kuhikuhi papaʻai i hana ʻia e kāu kauka a i ʻole dietitian. Hiki iā ʻoe ke kipa aku i ka pūnaewele Cholesterol Education Program (NCEP) pūnaewele no ka ʻike pili i ka papaʻai ma http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i Gemfibrozil ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻeha ka ʻōpū
  • puʻuwai puʻuwai

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • ʻeha ʻeha, palupalu, a nāwaliwali paha
  • ʻike hihi

ʻO kahi lāʻau i kapa ʻia ʻo clofibrate (Atromid-S; ʻaʻole i loaʻa hou ma ka US), he ʻano like ia me gemfibrozil, i ʻike ʻia e lilo i maʻi ʻaʻai, maʻi gallbladder, a me ka ʻeha o ka ʻōpū e alakaʻi ai i ka appendectomy. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hiki i Gemfibrozil ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).


E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a mamao aku mai ka mālamalama, ka wela a me ka momona o ka wela (ʻaʻole i loko o ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

  • ʻōpū o ka ʻōpū
  • pāhoehoe
  • ʻeha puʻupuʻu a me nā ʻeha
  • nausea
  • ka luaʻi

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka gemfibrozil.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Lopid®
Nānā Hou - 09/15/2017

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