ʻO Azathioprine
Anter
- Ma mua o ka lawe ʻana i ka azathioprine,
- Hoʻokumu paha ʻo Azathioprine i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā mea i helu ʻia i ka ʻARlelo Aʻoaʻo IMPORTANT, e kāhea koke i kāu kauka.
- Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:
Hiki i ka Azathioprine ke hoʻonui i kou makaʻu i ka hoʻomohala ʻana i kekahi ʻano maʻi ʻaʻai, ʻo ia hoʻi ka maʻi ʻaʻai a me ka lymphoma (ka maʻi ʻaʻa e hoʻomaka i nā hunaola e hakakā i ka maʻi). Inā ua loaʻa ʻoe i kahi transplan kidney, aia paha i kahi kiʻekiʻe kiʻekiʻe aʻe e hoʻomohala ʻoe i ka maʻi ʻaʻai inā ʻaʻole ʻoe e lawe i ka azathioprine. E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ʻaʻai a inā ʻoe e lawe a lawe paha i nā ʻākena alkylating e like me chlorambucil (Leukeran), cyclophosphamide (Cytoxan), a i ʻole melphalan (Alkeran) no ka maʻi ʻaʻai. E hoʻemi i ka makaʻu e hoʻomohala ʻoe i ka maʻi ʻaʻai o ka ʻili, e hōʻalo i ka hoʻolōʻihi ʻia ʻana a i ʻole kūpono ʻole i ka lā a komo i nā lole pale, nā aniani aniani, a me nā pale pale lā. E haʻi koke i kāu kauka inā ʻike ʻoe i nā loli i kou ʻili a i ʻole nā puʻupuʻu a i ʻole nā lehulehu i nā wahi āpau o kou kino.
ʻO kekahi mau kāne ʻōpio a ʻōpio makua hoʻi i lawe i ka azathioprine hoʻokahi a i ʻole me kahi lāʻau lapaʻau ʻē aʻe i kapa ʻia he tumzer nekrosis factor (TNF) blocker e mālama ai i ka maʻi o Crohn (kahi ʻano e hoʻouka ai ke kino i ka uhi o ka ʻaoʻao digestive e hōʻeha ai i ka ʻeha, ka maʻi pākī, ka pohō kaumaha, a fiva) a i ʻole ulcerative colitis (kahi ʻano e kumu ai ka pehu a me nā ʻeha i ka uhi ʻana o ke kolona [ʻōpū nui] a me ke kīhāhā) hoʻomohala i ka lymphoma T-cell lymphoma (HSTCL). He ʻano koʻikoʻi ʻo HSTCL o ka maʻi ʻaʻai e kumu pinepine ai i ka make ma loko o kahi manawa pōkole. ʻAʻole ʻae ʻia ʻo Azathioprine e ka Food and Drug Administration (FDA) no ka mālama ʻana i ka maʻi o Crohn a i ʻole colitis ulcerative, akā hiki i nā kauka ke kuhikuhi i kekahi manawa iā azathioprine e mālama i kēia mau ʻano. Inā hoʻomohala ʻoe i kekahi o kēia mau ʻōuli i kou wā e lapaʻau ai, e kāhea koke i kāu kauka: ʻeha ka ʻōpū; kuni; ka wehewehe kaumaha i wehewehe ʻole ʻia; sweats i ka pō a palu maʻalahi a hoʻokahe paha.
Hiki i ka Azathioprine ke hōʻemi i ka helu o nā hunaola koko i loko o kou iwi iwi, kahi e kumu ai nā maʻi nui a weliweli paha i ke ola. ʻO ka makaʻu e hoʻemi ʻia ka nui o nā hunaola i loaʻa iā ʻoe ke kiʻekiʻe loa inā loaʻa iā ʻoe kahi ʻikepili kūpona (hoʻoilina). Kauha paha kāu kauka i kahi hoʻokolohua ma mua a i ʻole i kāu wā e mālama ai e ʻike inā loaʻa iā ʻoe kēia mea pilikia. ʻO ka lawe ʻana i kekahi mau lāʻau e hoʻonui ai paha i ka makaʻu e hoʻoliʻiliʻi kou mau koko, no laila e haʻi i kāu kauka inā lawe ʻoe i kekahi o kēia mau mea: angiotensin hoʻololi i nā ʻenemi (ACE) mea kāohi e like me benazepril (Lotensin), captopril, enalapril (Vasotec), fosinopril , lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), Ramipril (Altace), a i ʻole trandolapril (Mavik); trimethoprim a me sulfamethoxazole (Bactrim, Septra); a me ribavirin (Copegus, Rebetol, Virazole). Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: he kahe koko ʻole a ʻeha paha; luhi nui loa; ʻili mae; ʻeha poʻo; huikau; ʻūpā; puʻuwai wikiwiki; pilikia i ka hiamoe; nāwaliwali; pokole o ka hanu; a me ka ʻāʻī ʻeha, ke kuni, ka haʻalulu, a me nā ʻōuli ʻē aʻe o ka maʻi. E kauoha kāu kauka i nā hoʻokolohua ma mua, i ka wā, a ma hope o kāu lāʻau e ʻike ai inā hoʻopili ʻia kāu mau kaola koko e kēia lāʻau.
E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.
Hoʻohana ʻia ʻo Azathioprine me nā lāʻau ʻē aʻe e pale aku ai i ka hōʻole transplant (hoʻouka kaua ʻana i nā mea i hoʻoulu ʻia e ka ʻōnaehana pale) i nā poʻe i loaʻa i nā transplants kidney. Hoʻohana ʻia ia e mālama i nā rheumatoid arthritis koʻikoʻi (kahi ʻano a ke kino e hoʻouka ai i kāna mau hui ponoʻī, e hōʻeha ai i ka ʻeha, ka pehu ʻana, a me ka nalo ʻana o ka hana) ke kōkua ʻole nā lāʻau ʻē aʻe. Aia ʻo Azathioprine i kahi papa o nā lāʻau i kapa ʻia ʻo immunosuppressants. Hana ia ma ka hoʻoliʻiliʻi ʻana i ka hana o ke kino pale o ke kino no laila ʻaʻole ia e hoʻouka i ka mea kanu i hoʻoili ʻia a i ʻole nā hono.
Hele mai ʻo Azathioprine ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi a ʻelua paha manawa o ka lā ma hope o ka ʻai ʻana. E lawe i ka azathioprine ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka azathioprine. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.
Inā ʻoe e lawe i ka azathioprine e mālama i ka rheumatoid arthritis, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi lāʻau haʻahaʻa a hoʻonui iki i kāu lāʻau ma hope o 6-8 mau pule a laila ʻaʻole ʻoi aku i hoʻokahi manawa i kēlā me kēia 4 pule. E hoʻoliʻiliʻi paha kāu kauka i kāu lāʻau i ka wā e kaohi ʻia ai kāu ʻano. Inā ʻoe e lawe i ka azathioprine e pale aku i ka hōʻole ʻana i nā transplant kidney, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi lāʻau kiʻekiʻe a hoʻoliʻiliʻi i kāu lāʻau i ka hoʻololi ʻana o kou kino i ka transplant.
Mālama ʻo Azathioprine i ka rheumatoid arthritis akā ʻaʻole ia e hoʻōla iā ia. Lawe ʻia i 12 mau pule ma mua o kou ʻike ʻana i ka pono piha o ka azathioprine. Pale ʻo Azathioprine i ka hōʻole transplant ʻoiai ʻoe e lawe i ka lāʻau. E hoʻomau i ka lawe azathioprine ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka azathioprine me ke kamaʻilio ʻole ʻana me kāu kauka.
Hoʻohana pū ʻia ʻo Azathioprine e mālama i ka colitis ulcerative (kahi ʻano e hoʻoulu ai a me nā ʻeha i ka pale o ke kolona [ʻōpū nui] a me ke kīhā) a me ka maʻi o Crohn. E kamaʻilio me kāu kauka e pili ana i nā pilikia e hiki ke hoʻohana i kēia lāʻau no kāu maʻi.
Kuhi ʻia kēia lāʻau i kekahi manawa no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.
Ma mua o ka lawe ʻana i ka azathioprine,
- e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka azathioprine, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa azathioprine. E noi i kāu kauka a kauka paha no kahi papa inoa o nā mea hoʻohui.
- e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E ʻōlelo pono i nā lāʻau i ʻōlelo ʻia i ka ʻARlelo Aʻo IMPORTANT a me kekahi o nā mea aʻe: allopurinol (Zyloprim); aminosalicylates e like me mesalamine (Apriso, Asacol, Pentasa, a me nā mea ʻē aʻe), olsalazine (Dipentum), a me sulfasalazine (Azulfidine); a me nā anticoagulants ('nā mea hōʻemi koko') e like me warfarin (Coumadin). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
- e haʻi i kāu kauka inā loaʻa kekahi ʻano maʻi, a i ʻole inā he maʻi ʻeha paha kāu.
- e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Pono ʻoe e hoʻohana i ka kaohi hānau inā ʻaʻole ʻoe e hāpai a i ʻole kāu pakanā ʻoiai ʻoe e lawe nei i kēia lāʻau. Kāhea i kāu kauka inā hāpai a i ʻole kāu pakanā ʻoiai ʻoe e lawe nei i ka azathioprine. Hoʻopilikia paha ʻo Azathioprine i ka fetus.
- inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha ʻoe e lawe nei i ka azathioprine.
- ʻaʻohe o nā lāʻau āpau i ka wā a ma hope paha o kāu mālama ʻana me ka walaʻau ʻole ʻana me kāu kauka.
Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.
E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.
Hoʻokumu paha ʻo Azathioprine i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- nausea
- ka luaʻi
- pāhoehoe
Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā mea i helu ʻia i ka ʻARlelo Aʻoaʻo IMPORTANT, e kāhea koke i kāu kauka.
- hūwī
- fiva
- nāwaliwali
- ʻeha mākala
Hoʻokumu paha kēia lāʻau i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu ke lawe nei ʻoe i ka azathioprine.
Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).
E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.
Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.
He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org
I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.
Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:
- nausea
- ka luaʻi
- pāhoehoe
- ʻeha ka ʻāʻī, ke kuni, ke anu, a me nā ʻōuli ʻē aʻe o ka maʻi
Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.
He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.
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