Mea Kākau: Clyde Lopez
Lā O Ka Hana: 26 Iulai 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
Umbralisib shows early promise for patients with marginal zone lymphoma
Wikiō: Umbralisib shows early promise for patients with marginal zone lymphoma

Anter

Hoʻohana ʻia ʻo Umbralisib e mālama i ka lymphoma palena liʻiliʻi (MZL; kahi maʻi lohi e ulu nei e hoʻomaka i kahi ʻano o nā hunaola keokeo e hakakā maʻamau i nā maʻi) i nā mākua i hoʻi a ʻole i pane ka maʻi ʻaʻai i kekahi ʻano lāʻau. Hoʻohana ʻia ia e mālama i ka lymphoma follicular (FL; kahi ʻano o ka maʻi ʻaʻai e hoʻomaka i nā hunaola keokeo) i nā mākua i hoʻi a ʻole i pane ka maʻi ʻaʻai i ʻekolu mau lāʻau ʻē aʻe. Aia ʻo Umbralisib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Umbralisib ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā me ka meaʻai. Lawe i ka umbralisib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka umbralisib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka lāʻau, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i umbralisib,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka umbralisib, aspirin, nā lāʻau ʻē aʻe, tartrazine (kahi kala melemele i kekahi mau meaʻai a me nā lāʻau i hana ʻia), a i ʻole kekahi o nā mea hana i nā papa umbralisib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā loaʻa ʻoe i kahi maʻi. Eia kekahi, e haʻi aku i kāu kauka inā i loaʻa i kāu ʻōpū a i ʻole nā ​​pilikia ʻōpū a i ʻole nā ​​maʻi ate.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i ka hānau keiki ʻana. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o kou hoʻomaka ʻana i ka mālama ʻana a hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kāu lapaʻau a no ka liʻiliʻi ma 1 mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā e hoʻohana i ka kaohi hānau i ka wā o kāu mālama ʻana me ka umbralisib a no 1 mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i ka umbralisib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Umbralisib i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i ka umbralisib a no 1 mau mahina ma hope o kāu hopena hope loa.
  • pono ʻoe e ʻike ʻo ka umbralisib ke kumu o nā pilikia momona i nā kāne. Hoʻopili paha kēia i kou hiki ke makua kāne i kahi keiki. E kamaʻilio me kāu kauka inā loaʻa kāu hopohopo e pili ana i ka momona.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


Inā ʻoe e nalo i kahi mahele ma lalo o 12 mau hola, e lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai a laila lawe i ka lāʻau aʻe i ka manawa i hoʻopaʻa ʻia. Eia nō naʻe, inā ʻoe e nalo i kahi mahele ma mua o 12 mau hola, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Umbralisib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • pāhoehoe
  • ka luaʻi
  • nausea
  • nalo ʻai ʻole
  • ʻeha ka ʻōpū
  • luhi
  • pehu o ka maka, lima a mau wāwae paha
  • ʻeha, kua, ʻāʻī, a ʻeha iwi paha
  • paʻakikī e hiamoe a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • fiva, ʻāʻī puʻupuʻu, ʻūhū, paʻakikī ka hanu ʻana, ka hū ʻana, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
  • pākī nui loa; ke koko i loko o kāu mau noho a ʻeleʻele paha, noho lōʻihi; mimi ʻulaʻula a ʻeleʻele paha; ka luaʻi ʻana i ke koko a i ʻole ka luaʻi kope lepo; a i ʻole ke kaʻe ʻana i ke koko
  • melemele nā ​​maka a i ʻole ka ʻili; abdominal eha; paopao a i ʻole ke kahe ʻana o ke koko; lilo o ka makemake ʻole; mimi melemele a ʻeleʻele paha; noho humuhumu; aiʻole kaʻeha ma kaʻaoʻao'ākau o luna o ka'ōpū
  • hūwī
  • hū me ke kuni a me ka huehue
  • pālū a ʻiliʻili paha
  • ʻehaʻeha a ʻeha paha ma kou ʻili, lehelehe, a waha paha

Hoʻokumu paha ʻo Umbralisib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka umbralisib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 04/15/2021

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