Mea Kākau: Virginia Floyd
Lā O Ka Hana: 9 Aukake 2021
HōʻAno Hou I Ka Lā: 16 Nowemapa 2024
Anonim
Dr. Motzer on the TIVO-1 Trial With Tivozanib in Advanced RCC
Wikiō: Dr. Motzer on the TIVO-1 Trial With Tivozanib in Advanced RCC

Anter

Hoʻohana ʻia ʻo Tivozanib e mālama i ka carcinoma cell renal holomua (RCC; maʻi ʻaʻai e hoʻomaka i nā puʻupaʻa) i hoʻi a pane ʻole paha i ʻelua mau lāʻau ʻē aʻe. Aia ʻo Tivozanib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki a hoʻolohi paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Tivozanib ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā me ka ʻole o ka meaʻai no nā lā 21 mua o kahi pōʻaiapuni 28 mau lā. E hana hou ʻia ke kalapona e like me ka ʻōlelo a kāu kauka. Lawe iā tivozanib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe iā tivozanib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻopau piha i nā capsule me ke kīʻaha wai; mai wehe iā lākou.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau a i ʻole manawa kūmau a paʻa mau paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me tivozanib.


Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana iā tivozanib,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka tivozanib, aspirin, tartrazine (kahi kala melemele i kekahi o nā meaʻai a me nā lāʻau i hana ʻia), nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i nā capsule tivozanib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono i kekahi o kēia mau mea: apalutamide (Erleada), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), enzalutamide (Xtandi), phenytoin (Dilantin, Phenytek), a me rifampin (Rifadin, Rimactane, ma Rifamate, i Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka a me kāu kauka lāʻau he aha nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St. Mai lawe iā St. John's wort ʻoiai e lawe ana iā tivozanib.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe kahi ʻeha i hoʻōla ʻole ʻia a i ʻole inā i loaʻa iā ʻoe ka maʻi kahe o ke kahe. he koko koko; puʻuwai puʻuwai; he puʻuwai puʻuwai; ke koko kiʻekiʻe; ka hopu ʻana; aiʻole ka puʻuwai, ka thyroid, ka hakuʻala a me ka maʻi ate.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i kahi keiki i kahi keiki. ʻAʻole ʻoe a i ʻole kāu pakanā e hāpai keiki ke lawe ʻoe iā tivozanib. Inā he wahine ʻoe, pono ʻoe e loaʻa i kahi hōʻike hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau, a pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kou mālama ʻana iā tivozanib a no 1 mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kāu mālama ʻana me tivozanib a no 1 mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Hiki i Tivozanib ke hoʻemi i ka momona i nā kāne a me nā wahine. Eia nō naʻe, ʻaʻole pono ʻoe e kuhi ʻaʻole hiki iā ʻoe a i ʻole kāu pakanā ke hāpai. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana iā tivozanib, e kāhea i kāu kauka. Hoʻopilikia paha ʻo Tivozanib i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā o kāu mālama ʻana me tivozanib a no 1 mau mahina ma hope o kāu hopena hope loa.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha ʻoe e lawe nei iā tivozanib. E haʻi paha kāu kauka iā ʻoe e hōʻoki i ka lawe ʻana i tivozanib ma ka liʻiliʻi he 24 mau lā ma mua o kāu kaʻina i hoʻonohonoho ʻia no ka mea hiki ke hoʻopili i ka hōʻeha ʻana o ka ʻeha. E haʻi aku kāu kauka iā ʻoe i ka manawa e hoʻomaka ai e lawe hou iā tivozanib ma hope o kāu ʻoki ʻana.
  • pono ʻoe e ʻike ʻo ka tivozanib ke kumu o ke kahe kiʻekiʻe. Pono e nānā pinepine ʻia kou kaomi koko ke lawe ʻoe iā tivozanib.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i ʻelua mau lāʻau i ka lā like e pani no kahi mea i hala.

Hoʻokumu paha ʻo Tivozanib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • pāhoehoe
  • nausea
  • ka luaʻi
  • luhi
  • nalo ʻai ʻole
  • Kaumaha emi
  • leo ʻē
  • ʻeha kua
  • ʻeha nā waha
  • ʻūhā
  • pokole o ka hanu

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀLU WAIWAI SPECIAL, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
  • nā noho koko a ʻeleʻele a tarry
  • koko i ka mimi
  • ka luaʻi a i ʻole ke kuʻe ʻana i ke koko
  • kahe ʻana o ke kahe mai ka gums
  • ka hopu ʻana, nā poʻo poʻo, nā loli ʻike, a huikau paha
  • ʻulaʻula, pehu, a ʻeha ma nā lima a me / a i ʻole nā ​​wāwae
  • huikau, ʻeha poʻo, ʻūpē, ʻeha o ka umauma, a i ʻole pōkole o ka hanu
  • ka pōkole o ka hanu a me ka pehu paha o nā kuʻekuʻe wāwae
  • ʻeha ka umauma a i ʻole kaomi; numbness a nāwaliwali paha ma kekahi ʻaoʻao o ke kino; ʻeha ma nā lima, kua, ʻāʻī a ʻāʻī; paʻakikī e kamaʻilio; pokole o ka hanu; ʻeha poʻo poʻo loa; loli ka hihiʻo; aiʻole ka pehu ʻana i nā lima a me nā wāwae

Hoʻokumu paha ʻo Tivozanib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

  • ʻehaʻeha o ka umauma nui; pokole o ka hanu; wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai; ʻeha poʻo; huikau; aiʻole ʻike hihi

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā tivozanib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • ʻO Fotivda®
Nānā Hou - 04/15/2021

Koho O Nā Mea Heluhelu

11 Pumping Hacks no nā mākua hānai i ka wā hele

11 Pumping Hacks no nā mākua hānai i ka wā hele

Hoʻopili mākou i nā huahana a mākou e manaʻo nei he pono no kā mākou poʻe heluhelu. Inā kūʻai ʻoe ma o nā loulou i kēia ʻaoʻao, loaʻa iā mākou kahi kōmike liʻiliʻi. Eia kā mākou hana.Nui nā kumu no ke...
ʻO ke kūlana Lithotomy: palekana?

ʻO ke kūlana Lithotomy: palekana?

He aha ke kūlana lithotomy?Hoʻohana pinepine ʻia ke kūlana lithotomy i ka wā o ka hānau hānau ʻana a me ke ʻoki ʻana ma ka wahi pelvic.Pili ia i ka moe ʻana ma kou kua me kou mau wāwae flexed 90 keke...