Gilteritinib

Anter

• Ma mua o ka lawe ʻana i gilteritinib,
• Hoʻokumu paha ʻo Gilteritinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole ia mau mea ma ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻokumu paha ʻo Gilteritinib i kahi hui koʻikoʻi a i ʻole hoʻoweliweli ʻino o nā ʻōuli i kapa ʻia he diffence syndrome. E nānā pono kāu kauka iā ʻoe e ʻike inā ke hoʻomohala nei ʻoe i kēia maʻi maʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: fiva, batukū, ʻūlū, loaʻa ke kaupaona hikiwawe, puʻupuʻu, hoʻoliʻiliʻi ka urination, pehu o kou mau lima a me kou mau wāwae, pōkole o ka hanu, paʻakikī ka hanu ʻana, ʻeha ka umauma, a ʻeha iwi paha. Kū paha kēia mau ʻōuli a 3 mau mahina ma hope o ka hoʻomaka ʻana o ka mālama ʻana me gilteritinib. I ka hōʻailona mua ke hoʻomohala nei ʻoe i ka maʻi hoʻokaʻawale, e kuhikuhi ana kāu kauka i nā lāʻau e mālama ai i ka maʻi, a e haʻi paha iā ʻoe e haʻalele i ka lawe ʻana i ka gilteritinib no kekahi manawa.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Ke alakaʻi alakaʻi) ke hoʻomaka ʻoe i ka lāʻau me gilteritinib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu.Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ʻo Gilteritinib e mālama i kekahi ʻano leukemia myeloid koʻikoʻi (AML) i ʻino a hoʻi mai paha ma hope o ka mālama ʻana me nā lāʻau chemotherapy ʻē aʻe. Aia ʻo Gilteritinib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kekahi mea kūlohelohe e pono ai e kōkua i nā hunaola maʻi ʻaʻai e hoʻonui.

Hele mai ʻo Gilteritinib ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā me ka ʻole a me ka ʻole o ka meaʻai no 6 mau mahina. Lawe i ka gilteritinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka gilteritinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa i ka wai; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Hiki i kāu kauka ke hoʻoponopono i kāu lāʻau a i ʻole manawa kūmau a paʻa mau paha i kāu mālama ʻana e kaukaʻi ʻia i ke ʻano o ka maikaʻi o ka lāʻau no ʻoe a inā ʻoe e ʻike i nā hopena ʻaoʻao. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ka gilteritinib inā ʻoe e ʻoluʻolu. Mai hōʻoki i ka lawe ʻana i ka gilteritinib me ka walaʻau ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i gilteritinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka gilteritinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka papa gilteritinib E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: kekahi antifungals e like me fluconazole (Diflucan), itraconazole (Onmel, Sporanox), a me ketoconazole; clarithromycin (Biaxin, i PrevPac); escitalopram (Lexapro); fluoxetine (Prozac); kekahi mau lāʻau no ka maʻi pale maʻi (HIV) a i ʻole loaʻa i ka maʻi maʻi maʻi maʻi (AIDS) e like me efavirenz (Sustiva, i Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ma Kaletra), a saquinavir (Hoʻokele); kekahi mau lāʻau no ka hopu ʻana e like me ka carbamazepine (Carbatrol, Epitol, Tegretol, a me nā mea ʻē aʻe), phenobarbital, a me phenytoin (Dilantin, Phenytek); nefazodone; pioglitazone (Actos); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); a me sertraline (Zoloft). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me gilteritinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa a i ʻole loaʻa iā ʻoe kahi QT interval hoʻolōʻihi (kahi puʻuwai puʻuwai kūpono ʻole e hiki ai i ka nāwaliwali, nalowale o ka ʻike, hopu ʻana, a make koke paha); kahi puʻuwai lohi, wikiwiki, a i ʻole kaulike ʻole; aiʻole nā ​​pae haʻahaʻa o ka potassium a magnesium paha i kou koko.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i kahi keiki i kahi keiki. ʻAʻole hāpai ʻoe a me kāu pakanā ʻoiai ʻoe e lawe nei iā gilteritinib. Inā he wahine ʻoe, pono ʻoe e hoʻokolohua hāpai keiki ma ka liʻiliʻi he 7 mau lā ma mua o kou hoʻomaka ʻana i ka lāʻau, a pono ʻoe e hoʻohana i ka kaohi hānau i kāu wā e mālama ai a no 6 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 4 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i gilteritinib, e kāhea i kāu kauka. Hoʻopilikia paha ʻo Gilteritinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā o kāu mālama ʻana me gilteritinib a no 2 mau mahina ma hope o kāu hopena hope loa.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia naʻe, inā he emi ia ma mua o 12 mau hola ma mua o kāu mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Gilteritinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha hui a ʻeha ʻeha paha
• luhi loa
• nausea
• ka luaʻi
• pāhoehoe
• ʻeha nā waha
• hoʻololi i ka hiki ke ʻono i ka meaʻai
• ʻeha poʻo
• nalo ʻai ʻole
• paʻakikī e hiamoe a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole ia mau mea ma ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• ka hopu ʻana; ʻeha poʻo; hoʻemi i ka makaʻala; huikau; a i ʻole hoʻololi i ka hihiʻo
• wikiwiki, kuʻi, a i ʻole kuʻi puʻuwai puʻuwai; maule ana; nalowale o ka ʻike; aiʻole ka hopu ʻana
• ʻeha mau e hoʻomaka i ka wahi o ka ʻōpū akā hiki ke pālahalaha i ka hope i hiki ke kū ʻia me ka ʻole a me ka ʻole a me ka luaʻi

Hoʻokumu paha ʻo Gilteritinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kahi hoʻokolohua hoʻokolohua ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me gilteritinib. E kauoha pū kāu kauka i kekahi mau hoʻokolohua lab a ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino iā gilteritinib. Hiki paha i kāu kauka ke kauoha i kahi electrocardiogram (ECG; hoʻāʻo e ana i ka hana uila i ka puʻuwai) ma mua a i kāu wā e lapaʻau ai.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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