Encorafenib

Anter

• Ma mua o ka lawe ʻana i ka encorafenib,
• Hoʻokumu paha ʻo Encorafenib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Encorafenib me ka binimetinib (Mektovi) e mālama ai i kekahi ʻano melanoma (kahi ʻano maʻi ʻaʻai o ka ʻili) i pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a i ʻole hiki ke hemo ʻia e ka ʻoki kino. Hoʻohana ʻia ia me cetuximab (Erbitux) e mālama i kekahi ʻano maʻi ʻaʻai kolona i nā mākua i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino ma hope o kekahi mau lapaʻau. Aia ʻo Encorafenib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i mea e hōʻoki a hoʻolohi ai paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Encorafenib ma ke ʻano he capsule e lawe ma ka waha. Lawe mau ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i kēlā me kēia lā. E lawe i ka encorafenib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka encorafenib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka lāʻau, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

E hoʻemi paha kāu kauka a i ʻole no ka manawa kūloko a paʻa mau paha i kāu mālama ʻana inā e ʻike ʻoe i nā hopena ʻaoʻao. E pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me ka encorafenib.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka encorafenib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka encorafenib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i loko o ka capsule encorafenib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana mea kanu ʻē aʻe āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: amiodarone (Nexterone, Pacerone), carbamazepine (Carbatrol, Teril, a me nā mea ʻē aʻe), citalopram (Celexa), clarithromycin (Biaxin, i Prevpac), diltiazem (Cardizem, Cartia, Diltzac, a me nā mea ʻē aʻe), disopyramide (Norpace), erythromycin (EES, PCE, a me nā mea ʻē aʻe), efavirenz (Sustiva, ma Atripla), indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole, modafinil (Provigil), nefazodone, nelfinavir (Viracept), nevodone ), phenobarbital, phenytoin (Dilantin, Phenytek), procainamide, quinidine (in Nuedexta), rifampin (Rifadin, Rimactane, in Rifamate, in Rifater), ritonavir (Norvir, in Kaletra), sotalol (Betapace, Sotylize), ʻO Calan, Verelan, ma Tarka). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka encorafenib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St John.
• e haʻi i kāu kauka inā loaʻa a i ʻole loaʻa iā ʻoe kahi QT interval hoʻolōʻihi (kahi puʻuwai puʻuwai kūpono ʻole e hiki ai i ka nāwaliwali, ka nalowale o ka ʻike, ka hopu ʻana, a me ka make koke), nā pae haʻahaʻa o ka potassium a me ka magnesium i loko o kou koko, ka puʻuwai ʻole, a i ʻole maʻi maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau. Pono ʻoe e hoʻohana i kahi kaohi hānau nonhormonal e pale ai i ka hāpai ʻana i ka wā o kāu mālama ʻana me encorafenib a no 2 mau pule ma hope o kāu hopena hope loa. Hiki i Encorafenib ke hoʻēmi i ka pono o nā kaola haʻi waha (nā lāʻau kaohi hānau), no laila he mea nui ia e hoʻohana i kahi ʻano nonhormonal o ka kaohi hānau. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana o ka kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i ka encorafenib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Encorafenib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka wā e lawe ana ʻoe i ka encorafenib a no 2 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka encorafenib.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā aia ma waena o 12 mau hola o ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Encorafenib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• luhi
• fiva
• nausea
• ʻeha ka ʻōpū
• kōpaʻa
• ʻeha poʻo
• ʻūpā
• ʻulaʻula, pehu, numbness a me ka ʻiliʻili ʻana i nā lima a me nā kapuwaʻi o nā wāwae
• mānoanoa ʻili
• hūwī
• ʻili maloʻo
• poho lauoho
• ʻeha hui a ʻeha ʻeha paha
• loli i ka ʻono
• ʻeha kua
• huehue
• kahe ʻana ka ihu

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• ʻino, maʻule, a me ka maʻule
• loli ka hihiʻo
• hoʻololi ka ʻili e like me ka wart hou, kahi ʻeha a ʻulaʻula hoʻi i hoola ʻole, kahi hoʻololi i ka nui a i ʻole ke kala o ka mole
• kahe koko ʻole ʻana a palapū paha
• ʻeleʻele, hoʻolōʻihi, a i ʻole nā ​​noho noho koko
• kahe ana ke koko

Hiki i Encorafenib ke hoʻonui i ka makaʻu o ka ulu ʻana i ka maʻi ʻaʻai, me ka maʻi ʻaʻai ʻili. E nānā kāu kauka i kou ʻili ma mua o ka mālama ʻana, i kēlā me kēia 2 mahina i ka wā o ka mālama ʻana, a a i 6 mau mahina ma hope o kāu hopena hope loa o ka encorafenib no nā ʻōuli o ka maʻi ʻaʻai ʻili. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Encorafenib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. Mai wehe i ka desiccant (maloʻo maloʻo) mai ka ʻōmole.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mālama i nā manawa a pau me kāu kauka, kauka maka, a me ka hale hana. E kauoha kāu kauka i kahi hoʻokolohua lab ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me ka encorafenib. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab, me nā hoʻokolohua maka, e nānā i ka pane o kou kino i ka encorafenib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Braftovi^®