Pākuʻi Brodalumab

Anter

• Ma mua o ka hoʻohana ʻana i ka injection brodalumab,
• Hoʻokumu paha ʻo Brodalumab injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀINA AOAO PAHU a i ʻole ʻĀpana KĀNĀWAI, e kelepona koke i kāu kauka:

ʻO kekahi poʻe i hoʻohana i ka injection brodalumab i loaʻa nā manaʻo suicidal a me ka lawena (e noʻonoʻo e pili ana i ka hōʻeha a pepehi paha iā ia iho a i ʻole ke hoʻolālā ʻana a hoʻāʻo paha e hana pēlā). ʻAʻole i ʻike ʻia inā he inikua brodalumab ke kumu o nā manaʻo suicidal a me ka lawena. E haʻi i kāu kauka a me kāu kauka lāʻau inā loaʻa iā ʻoe kahi moʻolelo o ke kaumaha a i ʻole nā ​​manaʻo suicidal. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: kahi hou a i ʻole ke kaumaha kaumaha a hopohopo paha; mau manaʻo no ka pepehi kanaka, make ʻana, a hōʻeha paha iā ʻoe iho, a i ʻole ke hoʻolālā a hoʻāʻo ʻana paha e hana pēlā; nā hoʻololi i kāu hana a i ʻole ʻano makemake; a i ʻole ke hana ʻana ma nā manaʻo hoʻoweliweli. E hāʻawi aku kāu mea mālama ola iā ʻoe i kahi Kāleka Pahu Patient me kahi papa inoa o nā ʻōuli. Inā kū kekahi o kēia mau ʻōuli, pono ʻoe e kōkua koke i ke olakino. Lawe i ke kāleka me ʻoe i nā manawa āpau i kāu mālama ʻana me ka injection brodalumab, a hōʻike iā ia i kāu poʻe lawelawe mālama ola āpau.

Ma muli o ka makaʻu o nā manaʻo suicidal a me ka lawena me kēia lāʻau, loaʻa wale ka injection brodalumab ma o kahi papahana kūikawā i kapa ʻia ʻo Siliq REMS^®. Pono ʻoe, kāu kauka, a me kāu kauka lāʻau e kau inoa i loko o kēia papahana ma mua o ka loaʻa ʻana o ka injection brodalumab. Pono nā kānaka āpau i kuhikuhi ʻia i ka hoʻopili brodalumab e loaʻa i kahi kauka mai kahi kauka i hoʻopaʻa inoa ʻia me Siliq REMS^® a hoʻopiha i ke kuhikuhi ma kahi kauka lāʻau i hoʻopaʻa inoa ʻia me Siliq REMS^® i mea e loaʻa ai kēia lāʻau. E noi i kāu kauka no ka ʻike hou aku e pili ana i kēia papahana a pehea ʻoe e loaʻa ai i kāu lāʻau.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ka injection brodalumab a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka hoʻohana ʻana i ka injection brodalumab.

Hoʻohana ʻia ka injection Brodalumab e mālama i ke kaulike a hiki i ka plake psoriasis (ka maʻi ʻili kahi e hana ai nā ʻulaʻula, scaly patch ma kekahi mau wahi o ke kino) i ka poʻe nona ka lāʻau ʻoi loa e mālama ʻia e nā lāʻau kumuhana wale nō a ʻaʻole i mālama maikaʻi ʻia me nā lāʻau ʻē aʻe. ʻO ka injection Brodalumab i loko o ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ka pale ʻana i ka hana o kekahi mea kūlohelohe i loko o ke kino e kumu i nā ʻōuli o ka psoriasis.

Hele mai ʻo Brodalumab injection ma ke ʻano he wai i loko o kahi syringe i hoʻomākaukau ʻia e injected subcutaneously (ma lalo o ka ʻili). Hoʻokomo pinepine ʻia ia i hoʻokahi manawa i kēlā me kēia pule no nā mahele 3 mua a laila hoʻokahi manawa i kēlā me kēia 2 mau pule. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E hoʻohana pono i ka hoʻopili brodalumab e like me ke kuhikuhi. Mai hoʻokomo i ka mea ʻoi aku a liʻiliʻi paha o ia mea a ʻaʻole hoʻi e pahu pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Hiki iā ʻoe ke hoʻopili i ka injection brodalumab iā ʻoe iho a i ʻole he hoaaloha a pili paha i hana i nā injection. Ma mua o kou hoʻohana ʻana i ka injection brodalumab no ka manawa mua, e heluhelu pono i nā ʻōlelo aʻo a ka mea hana. E noi i kāu kauka a kauka paha e hōʻike iā ʻoe a i ʻole i ke kanaka e hoʻopili ana i ka lāʻau pehea e ʻoki ai iā ia.

E hoʻohana i kēlā me kēia syringe prefilled hoʻokahi wale nō a hoʻopili i nā hopena āpau i ka syringe. Hoʻolei o nā nūnū i hoʻohana ʻia a me nā peni i loko o kahi pahu kūpaʻa kū ʻole. E kamaʻilio me kāu kauka a kauka paha e pili ana i ka hoʻolei ʻana i ka ipu kūpaʻa.

Inā ʻoe e hoʻohana ana i kahi syringe prefilled i hoʻomaʻalili ʻia, e hoʻokau i ka syringe ma kahi pālahalaha me ka ʻole o ka hemo ʻana i ka pāpale kui kele a ʻae iā ia e mehana i ka mahana o ka lumi no 30 mau minuke ma mua o ka hoʻohana ʻana. Mai hoʻāʻo e hoʻomehana i ka lāʻau i ka hoʻomehana ʻana iā ia i loko o ka hawewe, e waiho ana iā ia i loko o ka wai wela, a i ʻole ma o nā ʻano hana ʻē aʻe. Mai hoʻihoʻi i ka syringe i hana ʻia i loko o ka pahu hau ma hope o kona hiki ʻana i ka mahana wela.

Mai hoʻoluliluli i ka lāʻau.

E nānā mau i ka hopena brodalumab ma mua o kou hoʻopili ʻana iā ia. Pono ka lāʻau e akāka a kala ʻole i melemele iki. Mai hoʻohana i ka syringe inā ʻohu ke ao, wehe ʻia, a i ʻole loaʻa nā flakes a i ʻole nā ​​ʻāpana.

Mai hoʻohana i kahi syringe inā ua heleleʻi ʻia ia i ka ʻili paʻa. E haki paha kahi ʻāpana o ka syringe inā ʻaʻole hiki iā ʻoe ke ʻike i ka haki.

Hiki iā ʻoe ke hoʻopili i ka ʻume brodalumab ma nā wahi āpau o kou mau ʻūhā (ʻūhā luna), nā lima o luna, a i ʻole ka ʻōpū koe wale nō kou piko a me ka ʻāpana 2 ʻīniha (5 kenimika) a puni ia. I mea e hōʻemi ai i ka ʻeha a ʻulaʻula paha, e hoʻohana i kahi pūnaewele ʻokoʻa no kēlā me kēia ʻoki. Mai hoʻokomo i loko o kahi kahi e palupalu ai ka ʻili, ʻāʻī, ʻulaʻula, paʻakikī, mānoanoa, unahi, pā ʻia e ka psoriasis, a ma kahi e loaʻa ai nā ʻeha a i ʻole nā ​​kaha kau.

E haʻi paha kāu mea mālama ola iā ʻoe e haʻalele i ka hoʻohana ʻana i ka injection brodalumab inā ʻaʻole hoʻomaikaʻi kāu psoriasis ma waena o 12 a 16 mau pule o ka mālama ʻana. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka hoʻohana ʻana i ka injection brodalumab,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka brodalumab, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka brodalumab injection. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: cyclosporine (Gengraf, Neoral, Sandimmune) a me warfarin (Coumadin, Jantoven). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū me ka brodalumab injection, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi o Crohn (ke ʻano e hoʻouka ai ka ʻōnaehana pale i ka uhi o ka digestive tract e hōʻeha ai i ka ʻeha, ka palahī, ka pohō kaumaha, a me ke kuni. E haʻi paha kāu kauka iā ʻoe mai hoʻohana i ka injection brodalumab.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kekahi ʻano olakino.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka hoʻohana ʻana i ka injection brodalumab, e kāhea i kāu kauka.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e hoʻohana ana ʻoe i ka inikua brodalumab.
• nānā me kāu kauka e ʻike inā pono ʻoe e loaʻa i nā lāʻau āpau. He mea nui e loaʻa nā lāʻau āpau āpau i kūpono no kou mau makahiki ma mua o ka hoʻomaka ʻana i kāu mālama ʻana me ka injection brodalumab. ʻAʻohe o nā lāʻau lapaʻau i ka wā o kāu mālama ʻana me ke kamaʻilio ʻole ʻana me kāu kauka.
• pono ʻoe e ʻike i ka hoʻoheheʻe ʻana o brodalumab e hoʻemi i kou hiki ke hakakā i ka maʻi mai nā bacteria, nā mea hoʻomaʻi, a me nā fungi a hoʻonui i ka makaʻu e loaʻa ʻoe i kahi maʻi koʻikoʻi a weliweli paha i ke ola. E haʻi i kāu kauka inā loaʻa pinepine ʻoe i kekahi ʻano maʻi a i ʻole inā manaʻo a manaʻo paha ʻoe he ʻano maʻi paha kāu i kēia manawa. Hoʻopili kēia i nā maʻi liʻiliʻi (e like me nā ʻoki hāmama a i ʻole nā ​​ʻeha), nā maʻi i hiki a hele (e like me ka herpes a i ʻole nā ​​maʻi anuanu), a me nā maʻi maʻi ʻole e hele. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole ma hope koke paha o kāu mālama ʻana me ka inikū brodalumab, e kāhea koke i kāu kauka: ke kuni, ka hou, a me ke anuanu; ʻeha ka ʻili; uā; pokole o ka hanu; ʻeha ka ʻāʻī a paʻakikī paha i ka ale ʻana; mahana, ʻulaʻula, a ʻeha ʻeha a ʻeha paha ma kou kino; pāhoehoe; ʻeha ka ʻōpū; urination pinepine, ʻino, a ʻeha hoʻi; aiʻole nā ​​hōʻailona ʻē aʻe o ka maʻi.
• pono ʻoe e ʻike i ka hoʻohana ʻana i ka injection brodalumab e hoʻonui i ka makaʻu e hoʻomōhala ʻoe i ka maʻi puʻupuʻu (TB; kahi maʻi puʻuwai koʻikoʻi), keu hoʻi inā ua pā ʻia ʻoe i ka TB akā ʻaʻohe ou ʻōuli o ka maʻi. E haʻi aku i kāu kauka inā loaʻa paha iā ʻoe ka TB, inā ʻoe i noho i kahi ʻāina i maʻa mau ka TB, a i ʻole inā puni ʻoe i kekahi me ka TB. E nānā aku kāu kauka iā ʻoe no ka TB ma mua o ka hoʻomaka ʻana o ka lāʻau ʻana me ka inikua brodalumab a mālama paha iā ʻoe no ka TB inā he moʻaukala kou no ka TB a he TB ʻeleu paha kāu. Inā loaʻa iā ʻoe kekahi o nā ʻōuli o TB a i ʻole ke hoʻomohala i kekahi o kēia mau hōʻailona i kou wā e lapaʻau ai, e kāhea koke aku i kāu kauka: batukū, ʻūlū ʻana i ke koko a i ʻole nā ​​mucus, nāwaliwali a māluhiluhi paha, ka pohō o ke kaumaha, ka nele o ka makemake, nā anuanu, ke kuni, aiʻole ka sweats i ka pō.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E hoʻohana i ka lāʻau i hala ma hope ke hoʻomanaʻo ʻoe iā ia a laila hoʻomau i kāu papa hana maʻamau. Mai hoʻohana i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Brodalumab injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha poʻo
• ʻeha hui a ʻeha ʻeha paha
• nausea
• ʻeha, ʻulaʻula, ʻōpala, kahe ʻana o ke kahe, a i ʻole ka ʻili ma ka wahi i hoʻopili ʻia ka lāʻau

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀINA AOAO PAHU a i ʻole ʻĀpana KĀNĀWAI, e kelepona koke i kāu kauka:

• pākī ʻeha
• noho noho koko
• neʻe hiki ʻole a kāohi ʻole i ka neʻe ʻana o ka ʻōpū
• ʻeha ka ʻōpū a cramping paha
• kōpaʻa
• Kaumaha emi

Hoʻokumu paha ʻo Brodalumab injection i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama i nā syringes prefilled hale kūʻai brodalumab i loko o ka pahu hau, akā mai hoʻopili iā lākou. E mālama i nā syringes i kā lākou pahu pahu mua e pale ai i ka mālamalama. I ka wā e pono ai, hiki ke mālama ʻia nā syringes prefill i ka mahana o ka lumi a 14 mau lā. E hoʻolei i nā syringes ma hope o 14 mau lā ma ka mahana o ka lumi. Mai hoʻonoho i nā ʻakehe i mālama ʻia i mālama ʻia i ka mahana wela i loko o ka pahu hau.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mālama i nā manawa āpau me kāu kauka.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Siliq^®