Mea Kākau: Virginia Floyd
Lā O Ka Hana: 13 Aukake 2021
HōʻAno Hou I Ka Lā: 14 Nowemapa 2024
Anonim
Mepolizumab and Omalizumab - Evidence for Use in Severe Asthma -- BAVLS
Wikiō: Mepolizumab and Omalizumab - Evidence for Use in Severe Asthma -- BAVLS

Anter

Hoʻohana ʻia ka injection Mepolizumab me nā lāʻau ʻē aʻe i mea e pale aku ai i ka hū ʻana, ka hanu paʻakikī ʻana, ka paʻa ʻana o ka umauma, a me ka ʻūhū i hana ʻia e ka hānō i kekahi mau keiki he 6 makahiki a ʻoi a me nā mākua ʻaʻole kaohi ʻia ka hānō me kā lākou lāʻau lapaʻau hānō. Hoʻohana ʻia ia e mālama i ka granulomatosis eosinophilic me polyangiitis (EGPA; kahi ʻano e pili ana i ka hānō, nā pae kiʻekiʻe o nā hunaola keokeo, a me nā ʻōhū o ke kīʻaha koko) i nā mākua. Hoʻohana ʻia ka injection Mepolizumab e mālama i ka maʻi hypereosinophilic (HES; ka hui o nā maʻi koko e kū me nā kiʻekiʻe kiʻekiʻe o kekahi mau keʻokeʻo koko keʻokeʻo) i nā mākua a me nā keiki 12 mau makahiki a ʻoi paha i loaʻa kēia ʻano no 6 mau mahina a ʻoi paha. ʻO ka injection Mepolizumab i loko o ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ka pale ʻana i ka hana o kekahi mea kūlohelohe i ke kino e kumu i nā ʻōuli o ka hānō.

ʻO ka injection Mepolizumab e hele mai ma ke ʻano he syringe prefilled, he preinfined autoinjector, a i ʻole he pauka e hoʻopili ʻia me ka wai a injected ʻia ma lalo ʻiʻo (ma lalo o ka ʻili). Hāʻawi pinepine ʻia hoʻokahi manawa i kēlā me kēia 4 pule. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E hoʻohana pono i ka hoʻopili mepolizumab e like me ke kuhikuhi. Mai hoʻokomo i ka mea ʻoi aku a liʻiliʻi paha o ia mea a ʻaʻole hoʻi e pahu pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka. E hoʻoholo kāu kauka i ka lōʻihi o kāu lāʻau e pili ana i kou ʻano a pehea kou pane ʻana i ka lāʻau.


Hiki paha iā ʻoe ke loaʻa i kāu mahele lāʻau mua mepolizumab injection i ke keʻena o kāu kauka. Ma hope o kēlā, ʻae paha kāu kauka iā ʻoe a i kahi mea mālama paha e hāʻawi i nā injection i ka home. Ma mua o kou hoʻohana ʻana i ka mepolizumab injection iā ʻoe iho i ka manawa mua, e heluhelu i ka ʻike a ka mea hana no ka mea maʻi e hele pū me ka lāʻau. E noi i kāu kauka a kauka paha e hōʻike iā ʻoe a i ʻole i ke kanaka e hāʻawi ana i ka lāʻau pehea e ʻoki ai.

E hoʻohana i kēlā me kēia syringe a i ʻole autoinjector i hoʻokahi wale nō manawa a hoʻopili i nā hopena āpau i ka syringe a i ʻole ka autoinjector. E hoʻolei i nā kiʻiona i hoʻohana ʻia a i ʻole nā ​​autoinjectors i kahi pahu kūpaʻa kūpaʻa. E kamaʻilio me kāu kauka a kauka paha e pili ana i ka hoʻolei ʻana i ka ipu kūpaʻa.

Wehe i ka syringe prefilled a i ʻole autoinjector mai ka pahu hau. E kau iā ia ma kahi pālahalaha me ka ʻole o ka hemo ʻana o ka pāpale kui kele a ʻae iā ia e mehana i ka wela o ka lumi no 30 mau minuke (ʻaʻole i ʻoi aku ma mua o 8 mau hola) ma mua o kou mākaukau e hoʻokomo i ka lāʻau. Mai hoʻāʻo e hoʻomehana i ka lāʻau i ka hoʻomehana ʻana iā ia i loko o ka hawewe uila, e waiho ana i loko o ka wai wela, e waiho ana i ka lā, a i ʻole ma o nā ʻano hana ʻē aʻe.


Mai hoʻoluliluli i kahi syringe i loaʻa ka mepolizumab.

Inā ʻoe e hoʻohana nei i ka mepolizumab a loaʻa ka hānō, e hoʻomau i ka lawe a hoʻohana ʻana i nā lāʻau ʻē aʻe āpau a kāu kauka i kauoha ai e mālama i kāu hānō. Mai hoʻemi i kāu lāʻau o nā lāʻau hānō ʻē aʻe a i ʻole oki i ka lawe ʻana i nā lāʻau ʻē aʻe i kuhikuhi ʻia e kāu kauka ke ʻole ke kauka e haʻi iā ʻoe e hana pēlā. Makemake paha kāu kauka e hoʻoliʻiliʻi i nā lāʻau o kāu mau lāʻau ʻē aʻe.

E nānā mau i ka hopena mepolizumab ma mua o ka hoʻopili ʻana iā ia. E hōʻoia i ka hala ʻole o ka lā palena a maopopo ka wai a kala ʻole a melemele iki a ʻeleʻele iki. ʻAʻole pono i ka wai ke loaʻa nā hunaahi i ʻike ʻia. Mai hoʻohana i kahi syringe i paʻa i ka hau a i ʻole inā ʻohu ke wai a i ʻole loaʻa nā ʻāpana liʻiliʻi.

Hiki iā ʻoe ke hoʻopili i ka ʻume mepolizumab ma nā wahi āpau i mua o kou mau ʻūhā (ʻūhā luna) a i ʻole ʻōpū (ʻōpū) koe wale nō kou piko a me kahi ʻelua ʻīniha (5 centimita) a puni ia. Inā hōʻeha ka mea mālama i ka lāʻau, hoʻohana ʻia paha ka hope o ka lima luna. I mea e hōʻemi ai i ka ʻeha a ʻulaʻula paha, e hoʻohana i kahi pūnaewele ʻokoʻa no kēlā me kēia ʻoki. Mai hoʻokomo i loko o kahi kahi e palupalu ai ka ʻili, ʻulupā, ʻulaʻula, a paʻakikī paha a i kahi e loaʻa ai nā scars a i ʻole nā ​​kaha kau.


ʻAʻole hoʻohana ʻia ka injection Mepolizumab e mālama i ka hoʻouka kaua ʻana o nā ʻōuli hānō. Kauoha kāu kauka i kahi inhaler hana pōkole e hoʻohana i ka wā o ka hoʻouka. E kamaʻilio me kāu kauka e pili ana i ka mālama ʻana i nā ʻōuli o ka hoʻouka hānō koke.Inā hele a hewa kou mau ʻōuli hānō a i ʻole ke kū pinepine paha ʻoe i ka hānō, e kamaʻilio me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection mepolizumab,

  • e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka hoʻopili mepolizumab, nā lāʻau lapaʻau, a i ʻole kekahi o nā mea hana i ka inikū mepolizumab. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e haʻi i kekahi o kēia mau mea: oral corticosteroids e like me prednisone (Rayos) a i ʻole corticosteroid inhaled. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā ʻaʻole ʻoe i loaʻa i ka paukū (varicella) a i ʻole loaʻa paha iā ʻoe i kekahi ʻano maʻi ma muli o nā ilo.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka loaʻa ʻana o ka injection mepolizumab, e kāhea i kāu kauka.
  • inā loaʻa iā ʻoe kekahi ʻano olakino ʻē aʻe, e like me ka arthritis, a i ʻole eczema (kahi maʻi maʻi), e hōʻino paha lākou ke hoʻoliʻiliʻi ʻia kāu mahele lāʻau steroid. E haʻi i kāu kauka inā hana kēia a i ʻole inā ʻike ʻoe i kekahi o nā ʻōuli i lalo i kēia manawa: ka luhi nui loa, nāwaliwali o nā mākala, a me nā ʻehaʻeha; ʻeha hiki ʻole i ka ʻōpū, lalo ke kino, a i ʻole nā ​​wāwae; lilo o ka makemake ʻole; Kaumaha emi; huhū ʻōpū; ka luaʻi; pāhoehoe; ʻūpā; maule ana; kaumaha; ukiuki; a ʻeleʻele hoʻi o ka ʻili. ʻAʻole hiki i kou kino ke pale i ke koʻikoʻi e like me ke ʻoki ʻana, nā maʻi, ka hōʻeha hānō nui a i ʻole ka ʻeha i kēia manawa. Kāhea koke aku i kāu kauka inā maʻi ʻoe a e ʻike pono nā kahu mālama ola āpau e mālama iā ʻoe ʻike ua hōʻemi ʻoe i kāu hopena steroid steroid.
  • e haʻi i kāu kauka inā ʻaʻole ʻoe i pale ʻia i ka moa. Pono paha ʻoe e loaʻa i kahi lāʻau lapaʻau (shot) e pale aku ai iā ʻoe mai kēia maʻi.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E hoʻohana i ka lāʻau i hala ma hope ke hoʻomanaʻo ʻoe iā ia a laila hoʻomau i kāu papa hana maʻamau. Mai hoʻohana i kahi lāʻau pālua e pani no kahi mea i hala. Kāhea i kāu kauka inā haʻalele ʻoe i kahi lāʻau a he nīnau kāu e pili ana i ka mea e hana ai.

Hoʻokumu paha ka injection Mepolizumab i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻeha, ʻulaʻula, ʻōhū, mehana, wela, a i ʻole ʻānunu ma kahi o ka mepolizumab i kiki ʻia ai
  • ʻeha poʻo
  • ʻili a maloʻo a ʻili hoʻi me ka ʻulaʻula ʻole a me ka ʻula ʻole
  • ʻeha kua
  • ʻūpē mākala

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀLU WAIWAI SPECIAL, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • hū a paʻakikī i ka hanu ʻana
  • pokole o ka hanu
  • ʻūhā
  • paʻa paʻa o ka umauma
  • ʻōhinu
  • hives
  • hūwī
  • pehu o ka maka, waha, a me ke elelo
  • paʻakikī i ka ale ʻana
  • maule a poniuniu paha

Hoʻokumu paha ka injection Mepolizumab i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama i ka ʻume mepolizumab me ka pahu i loko o ka pahu hau a i ʻole ka pahu pahu i wehe ʻole ʻia ma ka mahana wela o ke keʻena no 7 mau lā, akā mai hoʻopili. Ke wehe ʻia mai ka carton, hiki ke mālama ʻia i ka injection mepolizumab i ka mahana wela no 8 mau hola.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka inikopa mepolizumab.

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka injection mepolizumab.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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