ʻO Sofosbuvir
Anter
- Ma mua o ka lawe ʻana iā sofosbuvir,
- Hoʻokumu paha ʻo Sofosbuvir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:
Ua hele a maʻi paha ʻoe i ka maʻi hepatitis B (kahi maʻi i hoʻopili ʻia i ke akepaʻa a e hōʻeha paha i ka ate) akā ʻaʻohe o nā ʻōuli o ka maʻi. I kēia hihia, hiki i ka lawe ʻana iā sofosbuvir ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i nā ʻōuli a e ʻoi aku ke koʻikoʻi a me ka weliweli o kāu maʻi. E haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe i ka maʻi maʻi maʻi hepatitis B. E kauoha aku kāu kauka i kahi hoʻokolohua koko e ʻike inā loaʻa a loaʻa paha iā ʻoe i ka maʻi hepitis B. E nānā pū kāu kauka iā ʻoe no nā hōʻailona o ka maʻi hepatitis B i ka manawa a no kekahi mau mahina ma hope o kāu lapaʻau. Inā pono, hiki i kāu kauka ke hāʻawi iā ʻoe i lāʻau e mālama ai i kēia maʻi ma mua a i kou wā e mālama ai me ka sofosbuvir. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole a ma hope paha o kāu lapaʻau ʻana, e kāhea koke aku i kāu kauka: luhi nui, melemele o ka ʻili a i ʻole nā maka, lilo i ka makemake ʻole, nausea, luaʻi, nā pale pale, ʻeha o ka ʻōpū, a me ka mimi ʻeleʻele.
E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka sofosbuvir.
E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana iā sofosbuvir.
Hoʻohana ʻia ʻo Sofosbuvir me ribavirin (Copegus, Rebetol, Ribasphere, a me nā mea ʻē aʻe) a i kekahi manawa kekahi lāʻau ʻē aʻe (peginterferon alfa [Pegasys]) e mālama i kekahi ʻano o ka hepatitis C mau (kahi maʻi viral e hoʻomau nei e hōʻino ai i ke ake) i nā mākua. Hoʻohana pū ʻia ʻo Sofosbuvir me ka ribavirin e mālama ai i kekahi ʻano o ka maʻi hepatitis C mau (kahi maʻi maʻi e hoʻomau nei e hōʻino ai i ke ake) i nā keiki he 3 mau makahiki a ʻoi paha. Aia ʻo Sofosbuvir i loko o ka papa o nā lāʻau antiviral i kapa ʻia he mau mea kāohi nāukana nukleotide. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi hepitis C (HCV) i ke kino. ʻAʻole hiki iā Sofosbuvir ke pale i ka hoʻolaha ʻana o ka maʻi hepatitis C i kekahi poʻe ʻē aʻe.
Hele mai ʻo Sofosbuvir ma ke ʻano he papa a me nā pelele e lawe ma ka waha. Lawe pinepine ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā. Lawe iā sofosbuvir ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā sofosbuvir e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.
Hiki ke ale ʻia nā pellets Sofosbuvir (me ka nau ʻole) a i ʻole hiki ke lawe ʻia me ka meaʻai. E hoʻomākaukau i kahi mahele o nā pellets sofosbuvir me ka meaʻai, e kāpīpī i ka paukū pellets āpau ma hoʻokahi a ʻoi paha punetēpō o ke anuanu a me nā lumi wela ʻole nā meaʻai momona e like me ka pudding, syrup syrup, ʻuala palaʻai, a me ka ʻaikalima. Lawe i ka hui holoʻokoʻa ma waena o 30 mau minuke o ka pīpī ʻana i nā pellets i ka meaʻai. I mea e hōʻalo ai i ka ʻawaʻawa hope, mai nāhelehele i nā pellets.
E hoʻomau i ka lawe sofosbuvir ʻoiai inā maikaʻi ʻoe. Pono e lawe pū ʻia ʻo Sofosbuvir me ka peginterferon alfa a me ka ribavirin a i ʻole me ka ribavirin wale nō. Inā lawe ʻia ʻo sofosbuvir me ka peginterferon alfa a me ka ribavirin, lawe mau ʻia ia no 12 mau pule. Inā lawe ʻia ʻo sofosbuvir me ka ribavirin wale nō, lawe mau ʻia ia no 12 a i ʻole 24 mau pule. Inā loaʻa ʻoe i ka maʻi ʻaʻai ʻāʻī a ke kali nei no kahi neʻe ʻana o ke ake, e lawe ʻoe i ka sofosbuvir me ka ribavirin a hiki i 48 mau pule a i ʻole a loaʻa iā ʻoe kahi hoʻoliʻi ate. Pili ka lōʻihi o kāu lapaʻau i kou ʻano, pehea kou pane ʻana i ka lāʻau, a inā ʻoe e ʻike i nā hopena ʻino. Mai hooki i ka lawe ʻana i sofosbuvir, peginterferon alfa, a i ʻole ribavirin, ke ʻole i haʻi ʻia e kāu kauka.
E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.
Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.
Ma mua o ka lawe ʻana iā sofosbuvir,
- e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka sofosbuvir, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa sofosbuvir a i ʻole nā pellets. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
- e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: amiodarone (Nexterone, Pacerone); kekahi mau lāʻau no ka maʻi ʻaʻai; nā lāʻau no ka maʻi kō; kekahi mau lāʻau no ka hopu ʻana e like me carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), oxcarbazepine (Trileptal), phenobarbital, a i ʻole phenytoin (Dilantin, Phenytek); kekahi mau lāʻau e kāohi i ka ʻōnaehana pale maʻi; rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); rifapentine (Priftin); tipranavir (Aptivus) a me ritonavir (Norvir); a me warfarin (Coumadin, Jantoven). ʻ telllelo paha kāu kauka iā ʻoe mai lawe i ka sofosbuvir inā ʻoe e lawe i hoʻokahi aʻoi aku paha o kēia mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me sofosbuvir, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
- e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St. ʻAʻole pono ʻoe e lawe i ka wort a St. John i kāu mālama ʻana me sofosbuvir.
- e haʻi aku i kāu kauka inā ua loaʻa ʻoe i kahi hoʻoliʻiliʻi ate a inā i loaʻa iā ʻoe a i ʻole loaʻa iā ʻoe ka maʻi pale maʻi kanaka (HIV), kekahi ʻano maʻi maʻi akepē ma mua o ka hepatitis C, nā maʻi puʻuwai, a i ʻole he dialysis
- e haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole hiki paha ke hāpai. Inā he kāne ʻoe, e haʻi i kāu kauka inā hāpai kāu hoa, hoʻolālā e hāpai, a i ʻole hiki paha i hāpai. Pono e lawe iā Sofosbuvir me ribavirin i hiki ke hōʻeha nui i ka fetus. Pono ʻoe e hoʻohana i ʻelua mau ʻano hana o ka kaohi hānau e pale ai i ka hāpai ʻana i loko ou a i ʻole kāu hoapili i ka wā o ka mālama ʻana me kēia mau lāʻau a no 6 mau mahina ma hope o kāu lapaʻau. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana āu e hoʻohana ai; hormonal contraceptives (pills kaohi hānau, pāʻina, implants, apo, a i ʻole nā injection) ʻaʻole holo pono paha i nā wahine e lawe nei i kēia mau lāʻau. Pono ʻoe a i ʻole kāu pakanā e hoʻāʻo no ka hāpai keiki ma mua o ka mālama ʻana, i kēlā me kēia mahina i kāu mālama ʻana, a no 6 mau mahina ma hope o kāu lapaʻau. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i kēia mau lāʻau a i ʻole ma loko o 6 mau mahina ma hope o kāu lapaʻau ʻana, e kāhea koke i kāu kauka.
- e haʻi i kāu kauka inā ʻoe e hānai umauma ana.
Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.
Inā ʻoe e hoʻomanaʻo i ka mahele lāʻau i hala i ka lā āu e manaʻo ai e lawe, e lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai ia lā. Eia nō naʻe, inā ʻaʻole ʻoe e hoʻomanaʻo i ka mahele lāʻau i hala a hiki i kekahi lā aʻe, kāpae i ka lāʻau i hala ʻole a hoʻomau i kāu papa hana maʻamau. Mai lawe i ʻelua mau kaha ma ka lā like.
Hoʻokumu paha ʻo Sofosbuvir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- pāhoehoe
- ʻeha poʻo
- ʻeha mākala
- paʻakikī e hiamoe a hiamoe paha
- ukiuki
- ʻūlili
- hūwī
Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:
- ʻili mae
- ʻūpā
- pokole o ka hanu
- nāwaliwali
- ʻeha ka ʻāʻī, ke kuni, ke anu, a me nā ʻōuli ʻē aʻe o ka maʻi
- hū, me ka ʻole o ka palapū
- ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
- hulahula
- pilikia i ka ale ʻana a me ka hanu ʻana
Hoʻokumu paha ʻo Sofosbuvir i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.
Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).
E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.
He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org
Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.
I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.
Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.
He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.
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