Mea Kākau: William Ramirez
Lā O Ka Hana: 20 Kepakemapa 2021
HōʻAno Hou I Ka Lā: 13 Nowemapa 2024
Anonim
Advancements in Estrogen Receptor–Positive Breast Cancer
Wikiō: Advancements in Estrogen Receptor–Positive Breast Cancer

Anter

ʻO ka lawe ʻana i ka estrogen e hoʻonui i ka makaʻu e hoʻomōhala ʻoe i ka maʻi ʻaʻai endometrial (cancer of the lining of the uterus [ʻōpū]) i kou hoʻomaʻamaʻa ʻana a i ʻole 15 mau makahiki ma hope o kou lapaʻau ʻana, inā ʻaʻole ʻoe i loaʻa i kahi hysterectomy (ʻoki e wehe i ka ʻōpū [ʻōpū ]). ʻO ka lōʻihi o kou lawe ʻana i ka estrogen, ʻo ka nui o ka makaʻu āu e hoʻomohala ai i ka maʻi ʻaʻai endometrial. Lawe i ka bazedoxifene me ka estrogen e hoʻemi i ka makaʻu e hoʻomohala ʻoe i ka maʻi ʻaʻai endometrial. Mai lawe i nā lāʻau ʻē aʻe i loaʻa ka estrogen i ka wā o kāu mālama ʻana no ka mea e hoʻonui paha kēia i ka makaʻu āu e hoʻomōhala ai i ka maʻi ʻaʻai endometrial. Ma mua o kou hoʻomaka ʻana i ka lawe ʻana i ka estrogen, e haʻi i kāu kauka inā loaʻa ʻoe a i loaʻa paha i ka maʻi ʻaʻai a inā loaʻa iā ʻoe ke kahe o ke kahe maʻamau. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka estrogen a me ka bazedoxifene inā loaʻa iā ʻoe ke kahe o ke kahe o ke kino. E nānā pono kāu kauka iā ʻoe ma muli o ka makaʻu āu e hoʻomōhala ai i ka maʻi ʻaʻai endometrial i ka wā a ma hope paha o kāu lāʻau. Kāhea koke i kāu kauka inā loaʻa iā ʻoe ke kahe o ke kahe wahine maʻamau ʻole i ka wā o kou mālama ʻana me ka estrogen.


Hiki i nā wahine i lawe i ka estrogen ke kiʻekiʻe o ka makaʻu o ka loaʻa ʻana a i ʻole ka hahau ʻana a i ʻole ke hoʻomohala ʻana i ke koko i nā akemāmā a i ʻole nā ​​wāwae, ka maʻi ʻaʻai umauma, a me ka dementia (ka nalowale ʻana o ka hiki ke noʻonoʻo, aʻo, a hoʻomaopopo) ma mua o nā wahine i lawe ʻole i ka estrogen. E haʻi i kāu kauka inā ʻoe a i ʻole kekahi o kou ʻohana i loaʻa i ke kahe koko a i ʻole ka maʻi ʻaʻai umauma, inā ʻoe i loaʻa i ka puʻuwai puʻuwai a i ʻole hahau ʻana, a inā he maʻi kāu e hoʻonui ai i ka makaʻu e loaʻa ʻoe i nā kahe koko. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka estrogen a me ka bazedoxifene. E haʻi pū aku i kāu kauka inā puhi ʻoe a hoʻohana paha i ka paka, a inā loaʻa iā ʻoe a i ʻole loaʻa i ke koko kiʻekiʻe, nā kiʻekiʻe o ke koko a me nā momona, ka maʻi diabetes, maʻi puʻuwai, lupus (kahi ʻano e hoʻouka ai ke kino i kāna mau pilikino ponoʻī e hōʻino ana. a me ka ʻōhū ʻana), nā puʻupuʻu o ka umauma, a i ʻole mammogram ʻokoʻa (x-ray o ka umauma i hoʻohana ʻia e ʻike ai i ka maʻi ʻaʻai umauma).

Hiki i nā hōʻailona aʻe ke hōʻailona i nā kūlana olakino koʻikoʻi i helu ʻia ma luna. Kāhea koke i kāu kauka inā ʻike ʻoe i kekahi o nā ʻōuli ma hope ke lawe nei ʻoe i ka estrogen a me ka bazedoxifene: koke, ʻeha ke poʻo ʻeha; lohi, luaʻi koʻikoʻi; nā pilikia ʻōlelo; ʻino a maʻule paha; pohihihi piha o ka hihiʻo; ʻike pālua; ka nāwaliwali a i ʻole ka helu ʻana o ka lima a me ka wāwae; ka ʻeha ʻana i ka ʻeha o ka umauma a i ʻole ke kaumaha o ka umauma; ʻū kahe i ke koko; hā pōkole o ka hanu; paʻakikī i ka noʻonoʻo ʻana, hoʻomanaʻo ʻana, a i ʻole ke aʻo ʻana i nā mea hou; hoʻololi nā puʻupuʻu a i ʻole nā ​​umauma ʻē aʻe; hoʻokuʻu mai nā nipples; a ʻeha paha, palupalu, a ʻulaʻula paha i hoʻokahi wāwae.


Pono ʻoe e nānā i kou mau umauma i kēlā me kēia mahina a loaʻa iā ʻoe kahi mammogram a me kahi hōʻike umauma e hana ʻia e ke kauka i kēlā me kēia makahiki e kōkua ai e ʻike i ka maʻi ʻaʻai umauma i ka wā hiki. E haʻi aku kāu kauka iā ʻoe pehea e nānā pono ai i kou umauma a inā paha ʻoe e loaʻa pinepine i kēia mau hoʻokolohua ma mua o hoʻokahi manawa i ka makahiki ma muli o kāu pilikino a pilikino ʻohana paha.

E haʻi i kāu kauka inā ke ʻoki ʻia ʻoe a e hoʻomaha ana ʻoe i kahi moe. E haʻi paha kāu kauka iā ʻoe e hōʻoki i ka lawe ʻana i ka estrogen a me ka bazedoxifene 4 a 6 mau pule ma mua o ke kaʻina ʻana a i ʻole kahi moe e hoʻomaha ai e hoʻemi i ka makaʻu e loaʻa iā ʻoe ke koko. Inā ʻoe e huakaʻi, e pono e ala aʻe a neʻe i kēlā me kēia manawa no ka mea ʻo ka noho iki no ka lōʻihi loa e hoʻonui ai i ka makaʻu e hoʻomohala ʻoe i nā huʻa koko.

Hiki iā ʻoe ke hana i nā hana e hōʻemi ai i ka makaʻu e hoʻomohala ʻoe i kahi pilikia olakino koʻikoʻi ʻoiai ʻoe e lawe nei i ka estrogen. ʻAʻole pono e hoʻohana ʻia ka Estrogen a me ka bazedoxifene e pale aku ai i ka maʻi puʻuwai, nā puʻuwai puʻuwai, nā hahau, a me nā dementia. ʻO ka lawe ʻana i ka lāʻau ʻoi loa o ka estrogen e kaohi i kāu mau ʻōuli a lawe wale i ka estrogen ke makemake ʻia hiki ke kōkua i ka hōʻemi ʻana i kēia mau pilikia. E kamaʻilio me kāu kauka mai kēlā me kēia manawa e hoʻoholo inā ʻoe e lawe i kahi lāʻau o ka estrogen a i ʻole e hoʻōki i ka lawe ʻana i ka lāʻau.


E kamaʻilio pinepine i kāu kauka e pili ana i nā pilikia o ka lawe ʻana i ka estrogen a me ka bazedoxifene.

Hoʻohana ʻia nā pākaukau Estrogen a me bazedoxifene e mālama ai i nā aniani wela (ke ʻano o ka mehana o ka pumehana, ʻo ka maka hoʻi, ka ʻāʻī, a me ka umauma) i nā wahine e ʻike nei i ka menopause (ke kahua o ke ola ke emi pinepine ka manawa menstrual a kū a ʻike paha nā wahine i nā ʻōuli ʻē aʻe. a hoʻololi ke kino). Hoʻohana pū ʻia ʻo ka estrogen a me ka bazedoxifene papa e pale aku ai i ka osteoporosis (ke ʻano a lahilahi a nāwaliwali nā iwi a haki maʻalahi) i nā wahine i hele i ka menopause. Aia ʻo Estrogen i loko o ka papa o nā lāʻau i kapa ʻia he hormones a ʻo bazedoxifene i kahi papa o nā lāʻau i kapa ʻia ʻo estrogen agonist – antagonists. Hana ka Estrogen ma ka hoʻololi ʻana i ka estrogen e hana maʻamau ʻia e ke kino. Hoʻohana ʻia ʻo Bazedoxifene e kāpae i ka hana o ka estrogen ma ka uhi o ka kōpū, e hoʻemi ana i ka makaʻu o ka ulu nui e hiki ai i ka maʻi ʻaʻai.

Hele mai ka hui Estrogen a me bazedoxifene ma ke ʻano he papa e lawe ma ka waha. Lawe pinepine ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā. Lawe i ka estrogen a me ka bazedoxifene ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka estrogen a me ka bazedoxifene e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i ka papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Hiki i ka Estrogen a me ka bazedoxifene ke kōkua i ka mālama ʻana i kāu mau hōʻailona inā ʻoe e hoʻomau i ka lawe ʻana i ka lāʻau. Mai hōʻoki i ka lawe ʻana i ka estrogen a me ka bazedoxifene me ka walaʻau ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka estrogen a me ka bazedoxifene,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka estrogen (i ka nui o nā lāʻau e hoʻololi a me ka mālama ʻana i ka hānau hānau), bazedoxifene, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka estrogen a me nā papa bazedoxifene. E noi i kāu kauka lāʻau a nānā paha i ka ʻike a ka mea hana no ka mea maʻi no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau i kuhikuhi ʻia a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻai pono, ke lawe nei ʻoe a hoʻolālā paha e lawe. E kuhikuhi pono i nā lāʻau i helu ʻia i ka ʻĀINA Aʻoaʻo koʻikoʻi a me nā mea o kēia mau ʻano: kekahi antibiotic me clarithromycin (Biaxin) a me erythromycin (E.E.S, E-Mycin); kekahi mau lāʻau antifungal me itraconazole (Sporanox) a me ketoconazole (Nizoral); a me kekahi mau lāʻau no ka hopu ʻana me ka carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, a me phenytoin (Dilantin); nā lāʻau hoʻōla hormonone thyroid; rifampin (Rifadin, Rimactane, ma Rifamate), a me ritonavir (Norvir, ma Kaletra). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St John.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka estrogen a me ka bazedoxifene.
  • e haʻi i kāu kauka inā ʻoi aku ʻoe ma mua o 75 mau makahiki a inā ʻoe i loaʻa i ka jaundice (kahi ʻano e hoʻomoe ai i ka ʻili a i ʻole nā ​​maka) i ka wā hāpai a i kāu mālama ʻana me kahi huahana estrogen. E haʻi pū aku i kāu kauka inā loaʻa iā ʻoe a i loaʻa paha i ka hānō, ka maʻi kō, ka maʻi epilepsy, ka maʻi migraine porphyria (ke ʻano e kūkulu ʻia nā mea ʻino i loko o ke koko a hoʻopilikia i nā ʻili a me nā ʻōnaehana), angioedema hoʻoilina. ʻo ka pehu i nā lima, nā wāwae, ke alo, ke alaloa, a i ʻole nā ​​ʻōpū), hypoparathyroidism (ke ʻano a ke kino e hoʻohua ʻole ai i ka hormone parathyroid), a i ʻole nā ​​maʻi kolo.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka estrogen a me ka bazedoxifene, e kāhea koke i kāu kauka. Hiki paha i ka Estrogen a me bazedoxifene ke hoʻopōʻino i ka fetus.
  • inā ʻoe e lawe ana i ka estrogen e pale aku ai i ka osteoporosis, e kamaʻilio me kāu kauka e pili ana i nā ala ʻē aʻe e pale aku ai i ka maʻi e like me ka hoʻomaʻamaʻa ʻana a me ka lawe ʻana i ka wikamina D a me / a i ʻole ka pāʻina calcium.

Mai ʻai i ka nui o ka huaʻulu a inu paha i ka wai huaʻikuʻi i ka wā e lawe ana i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Estrogen a me ka bazedoxifene ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nausea
  • puʻuwai puʻuwai
  • ʻeha ka ʻōpū
  • pāhoehoe
  • paʻa paʻa o ka ʻili
  • ʻeha ʻāʻī
  • eha ka 'ā'ī
  • ʻūpā

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • maka ʻōpuʻu
  • pehu o nā maka, maka, waha, alelo, a puʻu paha
  • hulahula
  • pilikia i ka hanu ʻana a i ʻole ke ale ʻana

Lawe i ka estrogen a me ka bazedoxifene e hoʻonui i ka makaʻu e hoʻomohala ʻoe i ka maʻi ʻaʻai o nā ovaries a i ʻole ka maʻi o ka gallbladder pono e mālama ʻia me ke ʻoki. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hiki i ka Estrogen a me ka bazedoxifene ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka ʻeke foil a me ka ʻūhā blister i komo mai i loko, pani paʻa loa ʻia, a ʻaʻole i hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. Inā loaʻa iā ʻoe ma mua o hoʻokahi kīke foil o ka lāʻau, mai wehe i ka ʻeke ʻelua a hiki i kou hoʻohana ʻana i nā lāʻau āpau i ka ʻeke mua. E kaha i ka lā e wehe ai ʻoe i kahi ʻeke pepa a hoʻolilo i nā lāʻau i hoʻohana ʻole ʻia i ka ʻeke 60 mau lā ma hope o kou wehe ʻana. Mai wehe i nā papa mai ka pahu blister a mākaukau ʻoe e lawe. Mai mālama i nā papa i loko o ka pahu pahu a mea hoʻokele pila paha.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • nausea
  • ka luaʻi
  • palupalu o ka umauma
  • ʻūpā
  • ʻeha ka ʻōpū
  • luhi
  • kahe koko

Mālama i nā manawa āpau me kāu kauka.

Ma mua o ka hoʻāʻo ʻana o kahi hale hana, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua e lawe nei ʻoe i ka estrogen a me ka bazedoxifene.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 02/15/2017

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