ʻO Vandetanib

Anter

• Ma mua o ka lawe ʻana i ka vandetanib,
• Hoʻokumu paha ʻo Vandetanib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hiki iā Vandetanib ke hoʻolōʻihi i QT (kahi puʻuwai puʻuwai kūpono ʻole e hiki ai i ka nāwaliwali, nalowale o ka ʻike, hopu ʻia, a make koke paha). E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole kekahi o kou ʻohana ka lōʻihi o QT syndrome (kahi ʻano hoʻoilina e nui ai ka hoʻolōʻihi ʻana o kahi kanaka i QT a i ʻole loaʻa paha iā ʻoe nā haʻahaʻa haʻahaʻa o ka calcium, potassium a me ka magnesium i kou koko, kahi puʻuwai kūlike ʻole, puʻuwai puʻuwai, a i ʻole he puʻuwai puʻuwai. E haʻi i kāu kauka a me ka kauka inā ʻoe e lawe ana i ka chloroquine (Aralen); clarithromycin (Biaxin, i Prevpac); haloperidol (Haldol); nā lāʻau no ke kuʻi puʻuwai kūlike ʻole e like me amiodarone (Cordarone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide, a me sotalol (Betapace); kekahi mau lāʻau no ka nausea e like me dolasetron (Anzemet) a me granisetron (Sancuso); methadone (Dolophine, Methadose); moxifloxacin (Avelox); a me pimozide (Orap). Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e hōʻoki i ka lawe ʻana i ka vandetanib a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino maule ana; ʻālohilohi; aiʻole ka nalowale o ka ʻike. Noho ʻo Vandetanib i kou kino no kekahi mau mahina ma hope o kou hōʻoki ʻana i ka lawe ʻana i ka lāʻau, no laila hiki ke hoʻomau i ka makaʻu i nā hopena i kēlā manawa.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua, e like me nā hoʻokolohua koko a me nā electrocardiograms (EKGs, nā hoʻāʻo e hoʻopaʻa i ka hana uila o ka puʻuwai) ma mua a maʻa mau i kou wā e hoʻomaʻamaʻa ai inā e palekana ʻoe e lawe i ka vandetanib. E kauoha pū kāu kauka i kēia mau hoʻokolohua i kēlā me kēia manawa ke hoʻololi ʻia kāu mahele lāʻau o vandetanib a i ʻole inā hoʻomaka ʻoe e lawe i kekahi mau lāʻau hou.

Ua hoʻonohonoho ʻia kahi papahana i kapa ʻia ʻo Caprelsa Risk Evaluation and Mitigation Strategy (REMS) e mālama i nā pilikia o kēia lāʻau. Hiki ke loaʻa iā ʻoe ka vandetanib inā kākau ʻia ke kauka nāna e kuhikuhi i kāu lāʻau i loko o ka papahana. Hiki iā ʻoe ke loaʻa i ka lāʻau lapaʻau wale nō mai kahi kauka i komo i ka papahana. E nīnau i kāu kauka inā he nīnau paha kāu e pili ana i ke komo ʻana i ka papahana a pehea e loaʻa ai kāu lāʻau.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me vandetanib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Ka ʻAina a me nā lāʻau lapaʻau (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm)or a i ʻole ka pūnaewele o ka mea hana e kiʻi i ke alakaʻi Medication.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i ka vandetanib.

Hoʻohana ʻia ʻo Vandetanib e mālama i kekahi ʻano o ka maʻi ʻaʻai thyroid i hiki ʻole ke mālama ʻia e ke ʻoki a i ʻole ua pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino. Aia ʻo Vandetanib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hoʻolohi a hoʻopau paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Vandetanib ma ke ʻano he papa e lawe ma ka waha. Lawe pinepine ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā. Lawe iā vandetanib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka vandetanib. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa āpau me ke kīʻaha wai. Mai hoʻokaʻawale, a nau, a ʻāpala paha iā lākou. Inā haki ʻole ʻia kahi papa, mai pale aku i kou ʻili. Inā kū kekahi pilina, holoi maikaʻi i ka wahi i hoʻopilikia ʻia me ka wai.

Inā ʻaʻole hiki iā ʻoe ke ale i nā papa āpau, hoʻopau paha ʻoe iā lākou i ka wai. E kau i ka papa i loko o ke kīʻaha i piha ka 2 auneke o ka wai inu ʻoluʻolu ʻole ʻia. Mai hoʻohana i kekahi wai ʻē aʻe e hoʻonā i ka papa. E hoʻoulu i ka hui ma kahi o 10 mau minuke a hiki i ka papa i nā ʻāpana liʻiliʻi loa; ʻaʻole e hoʻopau loa ka papa. Inu koke ka hui ʻana. E holoi i ke kīʻaha me kekahi auneke ʻē aʻe o ka wai kalepona ʻole a inu i ka wai holoi e ʻike pono ʻoe e ale i nā lāʻau āpau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o vandetanib a i ʻole e haʻi iā ʻoe e haʻalele i ka lawe ʻana i ka vandetanib no kekahi manawa i ka wā o kāu mālama ʻana. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ka vandetanib inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka vandetanib me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka vandetanib,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka vandetanib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā papa vandetanib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono i nā lāʻau i helu ʻia i ka ʻĀINA WAIWAI koʻikoʻi a me kekahi o kēia mau mea: carbamazepine (Tegretol, Carbatrol, Equetro), dexamethasone, phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, in Rifamate) , rifapentin (Priftin), a me nā homone thyroid e like me levothyroxine (Synthroid). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Pili pū paha nā lāʻau ʻē aʻe he nui me vandetanib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ia hoʻi ʻo St. Johns Wort.
• e haʻi i kāu kauka inā ua ʻeha ʻoe i ke koko a i ʻole he ʻano ʻē aʻe o nā pilikia kahe ʻana a inā loaʻa a loaʻa paha iā ʻoe ke kiʻekiʻe o ke koko, nā ʻano maʻi ʻili, nā maʻi lele, a me nā mumū, nā puʻupaʻa a me nā maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. ʻAʻole ʻoe e hāpai ma ke lawe ʻana i ka vandetanib a ma kahi o 4 mau mahina ma hope o kāu lapaʻau. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i ka lawe ʻana i ka vandetanib, e kāhea koke i kāu kauka. Hiki iā Vandetanib ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana.
• inā ke ʻoki nei ʻoe, e like me ke ʻoki niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i vandetanib.
• pono ʻoe e ʻike i ka vandetanib ʻoe e hiamoe ai, nāwaliwali, a i ʻole hoʻohoka i ka hihiʻo. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.
• e hoʻolālā e hōʻalo i ka hōʻike kūpono ʻole a hoʻolōʻihi ʻia paha i ka lā a komo i nā lole pale, nā aniani aniani, a me ka sunscreen. Hiki iā Vandetanib ke hana i kou ʻili i ka lā i kou wā e mālama ai a ma kahi o 4 mau mahina ma hope o ka hōʻoki ʻana i kāu lapaʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā loaʻa kāu mahele lāʻau aʻe i 12 mau hola a ʻoi paha, e lawe i ka lāʻau i hala i kou hoʻomanaʻo ʻana iā ia. Eia nō naʻe, inā e lawe ʻia ka lāʻau aʻe ma lalo o 12 mau hola, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Vandetanib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• puʻuwai puʻuwai
• nalo ʻai ʻole
• Kaumaha emi
• ʻeha ka ʻōpū
• ihu ihope
• luhi loa
• nāwaliwali
• paʻakikī e hiamoe a hiamoe paha
• kaumaha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• pāhoehoe
• ʻehu a huehue paha
• maloʻo, ihi, a ʻili ʻili paha
• pāhū a ʻeha paha ma ka ʻili a i ʻole ma ka waha
• ʻulaʻula o ka helehelena, lima a i ʻole nā ​​kapuaʻi o nā wāwae
• ʻeha a ʻeha pū paha
• fiva
• ʻeha o ka umauma (ʻoi aku paha ka maikaʻi me ka hanu hohonu a i ʻole ke kahe)
• hiccups a i ʻole ka hanu wikiwiki ʻana
• hā pōkole o ka hanu
• ʻū mau
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• loaʻa kaumaha kaumaha
• numbness a nāwaliwali paha o ka maka, ka lima, a me ka wāwae, keu hoʻi ma kekahi ʻaoʻao o ke kino
• huikau koke
• pilikia i ka ʻōlelo ʻana a i ʻole ka hoʻomaopopo ʻana
• pilikia pilikia i ka ʻike ʻana i hoʻokahi o nā maka ʻelua paha
• pilikia pilikia hiki ke hele a kaulike paha
• ʻeha poʻo poʻo loa
• ka hopu ʻana
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha

Hoʻokumu paha ʻo Vandetanib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā vandetanib. E nānā pinepine hoʻi kāu kauka i kou kaomi koko i kou wā e mālama ai me vandetanib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Caprelsa^®