Pazopanib

Anter

• Ma mua o ka lawe ʻana i pazopanib,
• Hoʻokumu paha ʻo Pazopanib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:
• Pākuʻi ʻia paha nā ʻōuli o ka overdose:

Hiki i ka Pazopanib ke kumu i ka hōʻeha ʻeha a i ʻole hoʻoweliweli ʻino. E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka: melemele o ka ʻili a i ʻole nā ​​maka; mimi ʻeleʻele; luhi loa; nausea; ka luaʻi; lilo o ka makemake ʻole; ʻeha ma ka ʻaoʻao ʻākau i luna o ka ʻōpū; a i ʻole ke kahe ʻana a i ʻole ka ʻeha ʻana.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua lab ma mua o kou hoʻomaka ʻana i ka pazopanib a ma ka liʻiliʻi i hoʻokahi manawa i ka mahina no nā mahina 4 mua o kou mālama ʻana a laila ma kahi manawa maʻamau e pono ai.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me pazopanib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i pazopanib.

Hoʻohana ʻia ʻo Pazopanib e mālama i ka carcinoma kōkō ʻoi loa (RCC, kahi ʻano o ke kanesa e hoʻomaka i nā hunaola o nā puʻupaʻa) i nā mākua. Aia ʻo Pazopanib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ka hoʻolohi a paʻa paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Pazopanib ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i ka ʻōpū nele i hoʻokahi manawa i ka lā, ma ka liʻiliʻi he 1 hola ma mua a i ʻole 2 mau hola ma hope o ka pāʻina ʻana. E lawe i ka pazopanib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā pazopanib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Hiki i kāu kauka ke hoʻoponopono i kāu mahele lāʻau o pazopanib i kou wā e hoʻoponopono ai a i ʻole hoʻopau paha i kāu lāʻau. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ka pazopanib inā ʻoe e ʻoluʻolu. Mai hōʻoki i ka lawe ʻana i ka pazopanib me ka walaʻau ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i pazopanib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka pazopanib, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa pazopanib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: cisapride (Propulsid) (ʻaʻole i loaʻa i ka U.S.). clarithromycin (Biaxin, i Prevpac); dofetilide (Tikosyn); erythromycin (E.E.S., E-Mycin, Erythrocin); ketoconazole (Nizoral); kekahi mau lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Cordarone), digoxin (Digitek, Lanoxicaps, Lanoxin), diltiazem (Cardizem, Dilacor, Tiazac, a me nā mea ʻē aʻe), disopyramide (Norpace), flecainide (Tambocor), mexiletine (Mexitil), procainamide ), propafenone (Rythmol), propranolol (Inderal, Innopran XL, ma Inderide), quinidine, sotalol (Betapace, Betapace AF, Sorine), a me verapamil (Calan, Isoptin, Verelan); moxifloxacin (Avelox); pimozide (Orap); rifampin (Rifadin, ma Rifamate, ma Rifater, Rimactane); ritonavir (Norvir, ma Kaletra); sparfloxacin (Zagam) (ʻaʻole loaʻa ma ka U.S.); a me thioridazine (Mellaril). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha ke launa pū me nā lāʻau ʻē aʻe he nui me ka pazopanib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā ua ʻeha ʻoe i ke koko a ua hoʻokahe paha i kou ʻōpū, ʻōpū, a i ʻole ka lolo i nā 6 mau mahina i hala a i ʻole ua ʻoki ʻia i nā lā 7 i hala. E haʻi aku i kāu kauka inā loaʻa iā ʻoe a i ʻole he waimaka paha i loko o kou ʻōpū a i ʻole ʻōpū. kahi pilina kūpono ʻole ma waena o ʻelua mau ʻāpana o kāu gastrointestinal tract; Gilbert's Syndrome (kahi ʻano genetical e hoʻopili ai i ke akepaʻa a hiki ke kumu i ka jaundice [melemele o ka ʻili a i ʻole nā ​​maka]); ke koko kiʻekiʻe; he hahau ʻana; he kuʻi puʻuwai kūpono ʻole; kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hiki ai ke hōʻeha i ka puʻuwai ʻole, maʻule, a make koke paha); he puʻuwai puʻuwai; ʻeha ka umauma; aiʻole ka puʻuwai a i ʻole ka maʻi thyroid.
• e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. ʻAʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ka pazopanib. Inā hāpai ʻoe i ka lawe ʻana i ka pazopanib, e kāhea i kāu kauka. Hoʻopilikia paha ʻo Pazopanib i ka fetus.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka pazopanib.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā aia ma waena o 12 mau hola o kāu kau palena hope e hoʻolālā ʻia, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Pazopanib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• kōpaʻa
• puʻuwai puʻuwai
• hoʻololi i ka hiki ke ʻono i ka meaʻai
• ʻeha hui a ʻeha ʻeha paha
• pehu o ka maka
• palupalu, ʻulaʻula nā lima o nā lima a me nā kapuaʻi o nā wāwae
• poho lauoho
• lahilahi, manamana mānoanoa a hulu lauoho paha
• hoʻololi i ke kala lauoho
• hoʻomālamalama ʻana i kahi o ka ʻili
• hūwī
• nāwaliwali
• kaumaha
• ʻoluʻolu maʻamau i nā mahana anuanu
• Kaumaha emi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

• wikiwiki a i ʻole kuʻi puʻuwai puʻuwai
• ʻeha ka umauma
• ʻeha ma nā lima, kua, ʻāʻī a ʻāʻā paha
• pokole o ka hanu
• ʻeha poʻo
• ʻolelo lohi a paʻakikī paha
• paupauaho a maʻule paha
• nāwaliwali a i ʻole ka helu ʻana o ka lima a me ka wāwae
• nā palapū hoola ʻole
• ʻeha o ka ʻōpū a huʻi paha
• pahu noho ʻeleʻele a lohi hoʻi
• koko ʻulaʻula i nā noho
• luaʻi koko
• ka luaʻi e like me nā pā kope
• koko i ka mimi
• ihu ihu
• kahe ana ke koko

Hoʻokumu paha ʻo Pazopanib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

• luhi loa

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Mea Palekana^®