Alemtuzumab Injection (Maʻi Lymphocytic Leukemia)

Anter

• Ma mua o ka loaʻa ʻana o ka piʻo alemtuzumab,
• Hoʻokomo paha ka hopena Alemtuzumab i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Loaʻa ʻo Alemtuzumab injection (Campath) ke loaʻa kahi papahana hoʻokaʻawale kūikawā kūikawā (Campath Distribution Program). I mea e loaʻa ai ka pahu alemtuzumab (Campath) pono e kau inoa kāu kauka me ka papahana, a hāhai i nā koi. E hoʻouna pololei ka Campath Distribution Program i nā lāʻau i ke kauka, ka haukapila, a i ʻole ka lāʻau lapaʻau.

Hoʻokomo paha ka pahu Alemtuzumab i kahi hōʻemi o ka nui o nā hunaola i hana ʻia e kou iwi iwi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ʻo ka palapū a me ke kahe ʻole ʻana, nā ʻulaʻula a ʻulaʻula a poni paha i kou kino, ʻili mae, nāwaliwali, a i ʻole ka luhi nui. Pono ʻoe e mālama i ke akahele e hōʻalo i ka ʻeha i kou wā e mālama ai no ka mea hiki ke kahe nui i ke kahe mai nā ʻoki liʻiliʻi a i ʻole nā ​​ʻōpala. E palaki i kou mau niho me kahi palaki niho palupalu, e hoʻohana i kahi pahi uila inā ʻoe e kahiʻumi, a pale i nā haʻuki pili a me nā hana ʻē aʻe e hōʻeha ai.

Hiki i ka hoʻopili ʻana iā Alemtuzumab ke hoʻemi i kou hiki ke hakakā i ka maʻi a hoʻonui i ka makaʻu e loaʻa ʻoe i kahi maʻi koʻikoʻi a i ʻole hoʻoweliweli ola. Kāhea koke aku i kāu kauka inā hoʻomohala ʻoe i nā hōʻailona o ka maʻi e like me ke kuni, ka puʻu, ʻeha ka ʻāʻī, a i ʻole kahi ʻeha ʻulaʻula, kaomi ʻana i ka pā, a lohi paha e hoʻōla.

Pono ʻoe e mālama i nā hana e hōʻemi ai i ka makaʻu o ka maʻi i kou wā e mālama ʻia me ka injection alemtuzumab. E kauoha aku kāu kauka i kekahi mau lāʻau e pale aku ai i ka maʻi. E lawe ʻoe i kēia mau lāʻau i kou wā e mālama ai a ma ka liʻiliʻi o 2 mau mahina ma hope o kāu lapaʻau. Lawe i kēia mau lāʻau e like me ke kuhikuhi. E holoi pinepine hoʻi ʻoe i kou mau lima a pale i ka poʻe i loaʻa i nā maʻi lele e like me ke kahe a me ke anu. Inā makemake ʻoe i kekahi ʻano o ke koko i ka wā o kou mālama ʻana me ka inikū alemtuzumab, pono ʻoe e loaʻa i nā huahana koko i hoʻoili ʻia (nā huahana koko i mālama ʻia e pale ai i kahi hopena koʻikoʻi e kū i ka poʻe i hoʻonāwaliwali i nā ʻōnaehana pale).

Hiki paha iā ʻoe ke ʻike i kahi hopena koʻikoʻi a make paha ke loaʻa ʻoe i kahi lāʻau o alemtuzumab injection. E loaʻa iā ʻoe kēlā me kēia mahele lāʻau o ka lāʻau i loko o kahi keʻena lapaʻau, a e nānā pono kāu kauka iā ʻoe ke loaʻa iā ʻoe ka lāʻau. E kauoha ana kāu kauka i kekahi mau lāʻau e pale ai i kēia mau hopena. E lawe koke ʻoe i kēia mau lāʻau i mua o ka loaʻa ʻana o kēlā me kēia lāʻau o alemtuzumab. E hoʻomaka kāu kauka iā ʻoe ma kahi lāʻau haahaa o alemtuzumab a hoʻonui iki i kāu lāʻau e ʻae ai i kou kino e hoʻoponopono i ka lāʻau. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole ma hope o kāu infusion, e haʻi koke i kāu kauka: fiva; haʻalulu; nausea; ka luaʻi; hives; ʻehu; ʻumeʻume; pilikia i ka hanu ʻana a i ʻole ke ale ʻana; hanu i ka hanu ʻana; ke ʻāʻī ʻana o ka ʻāʻī; pehu o nā maka, maka, waha, lehelehe, alelo a puʻu paha; hoarseness; ʻūpā; ʻālohilohi; maule ana; wikiwiki a i ʻole kōkō puʻuwai puʻuwai; a ʻehaʻeha paha.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua i ka wā a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka hoʻopiʻi alemtuzumab.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana o ka injection alemtuzumab.

Hoʻohana ʻia ke kīkala Alemtuzumab e mālama i ka leukemia lymphocytic mau ʻo B-cell (B-CLL; kahi ulu mālie e ulu ai ka maʻi ʻaʻai i loko o ke kino). Aia ʻo Alemtuzumab i ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ka hoʻoulu ʻana i ka ʻōnaehana pale e luku ai i nā hunaola maʻi ʻaʻai.

Loaʻa ʻo Alemtuzumab ma ke ʻano he injection (Lemtrada) i hoʻohana ʻia e mālama i nā sclerosis he nui (kahi maʻi kahi e holo pono ʻole ai nā ʻalalā; ʻike paha ʻoe i ka nāwaliwali, numbness, nalo ʻana o ka hui pū ʻana o nā mākala a me nā pilikia me ka hihi, kamaʻilio, a me ka mālama ʻana i ka maʻi ʻaʻa. ). Hāʻawi wale kēia monograf i ka ʻike e pili ana i ka hoʻopili ʻana o alemtuzumab (Campath) no B-CLL. Inā ʻoe e loaʻa ana i ka alemtuzumab no nā sclerosis he nui, e heluhelu i ka monograph i kapa ʻia ʻo Alemtuzumab Injection (Multiple Sclerosis).

Hele mai ʻo Alemtuzumab injection ma ke ʻano he hopena (wai) e hoʻopili ʻino ʻia (i loko o ke aa) ma kahi o 2 mau hola e ke kauka a kahu hānai paha i ka haukapila a i ʻole ke keʻena lapaʻau. I ka mua, hāʻawi pinepine ʻia ka pahu alemtuzumab i ka hoʻonui iki ʻana i nā lāʻau no 3 a 7 mau lā e ʻae ai i ke kino e hoʻomaʻa i ka lāʻau. Ke hoʻololi ke kino i ka mahele pono o ke alemtuzumab injection, hāʻawi pinepine ʻia ka lāʻau i ʻekolu mau pule ma nā lā ʻē aʻe (ʻo ka Pōʻakahi, Pōʻakolu, a me Pōʻalima) a hiki i 12 mau pule.

ʻO nā lāʻau i loaʻa iā ʻoe ma mua o kēlā me kēia kaha o ka alemtuzumab injection hiki ke hiamoe ʻoe. E makemake paha ʻoe e noi i kahi ʻohana a i ʻole hoa aloha e hele pū me ʻoe ke loaʻa iā ʻoe kāu lāʻau a lawe iā ʻoe i ka home ma hope.

ʻOiai e hoʻomaikaʻi hou kou ʻano ma mua o 4 a 6 mau pule ma hope o kou hoʻomaka ʻana i ka lāʻau me ka inikū alemtuzumab, e mau ana paha kāu hoʻomaʻamaʻa no 12 mau pule. E hoʻoholo kāu kauka inā e hoʻomau i kāu lāʻau lapaʻau a hoʻomaʻa paha i kāu lāʻau ma muli o ke ʻano o ka maikaʻi o ka lāʻau lapaʻau iā ʻoe a me nā hopena ʻaoʻao āu e ʻike ai.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka piʻo alemtuzumab,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka hoʻopili alemtuzumab a i ʻole nā ​​lāʻau ʻē aʻe.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i nā ʻano lapaʻau.
• E haʻi i kāu kauka inā hāpai ʻoe a i ʻole kāu pakanā paha e hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana o ka lāʻau ʻana a hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 3 mau mahina ma hope o kāu hopena hope loa Inā hāpai ʻoe i kou wā e mālama ʻia ai me ka hoʻopiʻi alemtuzumab, e kāhea koke i kāu kauka. Hiki paha iā Alemtuzumab ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka wā o ka mālama ʻana me alemtuzumab a no 3 mau mahina ma hope o ka hopena hope loa.
• ʻaʻohe o nā lāʻau lapaʻau ola i ka wā a ma hope koke paha o kāu mālama ʻana me ka ʻume alemtuzumab me ke kamaʻilio ʻole ʻana me kāu kauka. ʻO nā wahine e loaʻa ana i ka alemtuzumab injection ʻoiai e hāpai ana ka wahine hāpai i kā lākou pediatrician ʻoiai ʻaʻole hiki i kā lākou pēpē ke loaʻa nā lāʻau ola no kekahi manawa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana o ka alemtuzumab.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha ke loaʻa nei ʻoe i ka ʻume alemtuzumab.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hoʻokomo paha ka hopena Alemtuzumab i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• ʻeha ka ʻōpū
• pāhoehoe
• nalo ʻai ʻole
• ʻeha nā waha
• ʻeha poʻo
• hopohopo
• paʻakikī e hiamoe a hiamoe paha
• luliluli ʻole ʻana i kahi ʻāpana o ke kino
• ʻeha mākala

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• e hāʻule ana ma kekahi ʻaoʻao o ka maka; ka nāwaliwali koke a i ʻole ka helu ʻana o ka lima a me ka wāwae, keu hoʻi ma kekahi ʻaoʻao o ke kino; a i ʻole ka paʻakikī e ʻōlelo a hoʻomaopopo paha
• pehu i nā wāwae a me nā kuʻekuʻe wāwae, loaʻa ke kaupaona, luhi. a i ʻole mīmū hua (hiki i kekahi mau mahina a i ʻole mau makahiki ma hope o kāu hopena hope loa)

Hoʻokumu paha ʻo Alemtuzumab i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻākī ʻana o ka ʻāʻī
• paʻakikī i ka hanu ʻana
• ʻūhā
• hoʻemi urination
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• ʻulaʻula a poni paha i ka ʻili
• ʻili mae
• nāwaliwali
• luhi nui loa
• ʻeha ka ʻāʻī, ke kuni, ke anu, a me nā ʻōuli ʻē aʻe o ka maʻi
• nausea
• ka luaʻi
• hives
• hūwī
• ʻūlili
• pehu o nā maka, maka, waha, ʻāʻī, lehelehe, a alelo paha
• wikiwiki a i ʻole kuʻi puʻuwai puʻuwai
• maule ana
• ʻeha ka umauma

E noi i kāu kauka lāʻau i nā nīnau āu e pili ana i ka injection alemtuzumab.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Campath^®