Imatinib
Anter
- Ma mua o ka lawe ʻana i imatinib,
- Hoʻokumu paha ʻo Imatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka:
- Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:
Hoʻohana ʻia ʻo Imatinib e mālama i kekahi ʻano leukemia (ka maʻi ʻaʻai e hoʻomaka i nā hunaola keʻokeʻo) a me nā maʻi ʻino a me nā maʻi ʻē aʻe o nā huna koko. Hoʻohana ʻia ʻo Imatinib e mālama i kekahi ʻano o nā tumomoma stromal gastrointestinal (GIST; kahi ʻano tumo e ulu ana i nā paia o nā wahi digestive a pāhola paha i nā ʻāpana ʻē aʻe o ke kino). Hoʻohana ʻia ʻo Imatinib e mālama i nā protuberans dermatofibrosarcoma (kahi tumo i hana ʻia ma lalo o ka papa luna o ka ʻili) ke hiki ʻole ke hemo ʻia ka tumo, ua pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino, a ua hoʻi mai paha ma hope o ke kaha ʻana. Aia ʻo Imatinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i nā hunaola maʻi ʻaʻai.
Hele mai ʻo Imatinib ma ke ʻano he papa e lawe ma ka waha. Lawe pinepine ia me kahi pāʻina a me kahi kīʻaha wai nui i hoʻokahi a ʻelua mau manawa paha i ka lā. Lawe i ka imatinib ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe imatinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.
E ale i nā papa holoʻokoʻa; mai nahu a paopao iā lākou. Inā ʻoe e hoʻopā a hele mai i kahi pilina pololei me kahi papa i haki ʻia, holoi pono i kahi.
Inā hiki ʻole iā ʻoe ke ale i nā papa imatinib, hiki iā ʻoe ke waiho i nā papa āpau āu e pono ai no hoʻokahi mahele wai i loko o ke kīʻaha wai a wai wai ʻāpala. E hoʻohana i ka 50 milliliter (ma lalo iki o 2 auneke) o ka wai no kēlā me kēia papa 100-mg a me 200 milliliter (ma lalo iki o 7 auneke) o ka wai no kēlā me kēia pā 400-mg. E kuʻi me kahi puna a hū nā papa a inu koke i ka hui.
Inā ua haʻi aku kāu kauka iā ʻoe e lawe i ka 800 mg o imatinib, pono ʻoe e lawe i 2 o nā papa 400-mg. Mai lawe i 8 o nā papa 100-mg. Loaʻa ka hao i ka uhi papa, a e loaʻa iā ʻoe ka hao he nui inā lawe ʻoe i 8 o nā papa 100-mg.
Hiki i kāu kauka ke hoʻonui a hōʻemi paha i kāu lāʻau o imatinib i kāu wā e lapaʻau ai. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻaoʻao āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe imatinib ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i imatinib me ke kamaʻilio ʻole ʻana me kāu kauka.
Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.
Ma mua o ka lawe ʻana i imatinib,
- e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka imatinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa imatinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
- e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe.E haʻi pono i kekahi o kēia mau mea: acetaminophen (Tylenol), alprazolam (Xanax), amlodipine (Norvasc, ma Caduet, Lotrel, Tribenzor, a me nā mea ʻē aʻe), atazanavir (Reyataz), atorvastatin (Lipitor, ma Caduet), carbamazepine (Carbatrol, Equetro, Tegretol, nā mea ʻē aʻe), clarithromycin (Biaxin, ma Prevpac), cyclosporine (Gengraf, Neoral, Sandimmune), dexamethasone, ergotamine (Ergomar, ma Migergot, Cafergot), erythromycin (EES, Eryc, Erypedam, haʻi) , fentanyl (Duragesic, Subsys, Fentora, a me nā mea ʻē aʻe), fosphenytoin (Cerebyx), indinavir (Crixivan), hao, a i ʻole nā hao i loaʻa nā mea hoʻopili, isradipine, itraconazole (Onmel, Sporanox), ketoconazole, lovastatin (Altoprev), metoprolol (Lopressor (Lopressor) XL, ma Dutoprol), nefazodone, nelfinavir (Viracept), nicardipine (Cardene), nifedipine (Adalat CC, Procardia, a me nā mea ʻē aʻe), nimodipine (Nymalize), nisoldipine (Sular), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital, phenytoin ʻO Dilantin, Phenytek), pimozide (Orap), primidone (Mysoline), qui nidine (i Nuedexta), rifabutin (Mycobutin), rifampin (rifadin, rimactane, ma Rifamate, Rifater), ritonavir (Norvir, ma Kaletra, Technivie, Viekira), saquinavir (Fortovase, Invirase), simvastatin (Zocor, i Vytorin) sirolimus (Rapamune), tacrolimus (Astagraf XL, Envarsus XR, Prograf), telithromycin, triazolam (Halcion), voriconazole (Vfend), a me warfarin (Coumadin, Jantoven). Nui paha nā lāʻau ʻē aʻe e launa pū paha me imatinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
- e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
- e haʻi i kāu kauka inā he puʻuwai kou, i loaʻa i ka puʻuwai, kaoka, pākiko, a me nā maʻi ate.
- e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau, ʻaʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i imatinib a no 14 mau lā ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i ka lawe ʻana i imatinib, e kāhea i kāu kauka. Hoʻopilikia paha ʻo Imatinib i ka ʻōpū.
- e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i imatinib a no hoʻokahi mahina ma hope o kāu hopena hope loa.
- inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i imatinib.
- pono ʻoe e ʻike i ka imatinib e hoʻolilo ai iā ʻoe i ka palaho, hiamoe, a i ʻole kumu ʻino ʻole. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.
Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.
E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.
Hoʻokumu paha ʻo Imatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- pāhoehoe
- nausea
- ka luaʻi
- hoʻololi i ke ʻano o ka ʻono o nā mea
- ʻehaʻeha o ka waha a huʻu paha i loko o ka waha
- nalo ʻai ʻole
- Kaumaha emi
- puʻuwai puʻuwai a i ʻole indigestion
- waha maloo
- ʻeha poʻo
- pehu ami a ʻeha paha
- ʻeha iwi
- ʻūpī mākala, ʻehaʻeha, a ʻeha paha
- ʻalalā, ʻā. a i ʻole ka ʻiʻo ʻana i ka ʻili
- paʻakikī e hiamoe a hiamoe paha
- ka houʻu ʻana
- waimaka waimaka
- maka ʻākala
- ʻōhinu
- ʻili maloʻo
- hūwī
- ʻūlili
- loli ke kui
- poho lauoho
Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka:
- pehu a puni nā maka
- ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
- loaʻa kaumaha kaumaha
- pokole o ka hanu
- wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai
- ke kuʻi nei i ka momona a i ʻole ka mucus koko
- hoʻonui i ka urination, keu hoʻi i ka pō
- ʻeha ka umauma
- ʻili ʻana, ʻili ʻana, a i ʻole ka hoʻokahe ʻana i ka ʻili
- melemele o ka ʻili a me nā maka
- ke koko i ka noho
- ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
- flu-like me nā ʻōuli, ʻeha ka puʻu, kuni, nā anu, a me nā ʻōuli ʻē aʻe o ka maʻi
- ka luhi nui a i ʻole ka nāwaliwali
- ʻeha o ka ʻōpū a i ʻole bloating
Imatinib paha e hoʻolohi i ka ulu ʻana o nā keiki. E nānā pono ke kauka o kāu keiki i kona ulu pono ʻana. E kamaʻilio me kāu kauka o kāu keiki e pili ana i nā makaʻu o ka hāʻawi ʻana i imatinib i kāu keiki.
Hoʻokumu paha ʻo Imatinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.
E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.
He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org
Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.
I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.
Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:
- nausea
- ka luaʻi
- pāhoehoe
- hūwī
- pehu
- luhi loa
- ʻūpī mākala a i ʻole nā spasms
- abdominal eha
- ʻeha poʻo
- nalo ʻai ʻole
E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i imatinib.
Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.
He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.
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