Sirolimus

Anter

• E hoʻohana i nā ʻōmole o ka hopena, e hāhai i nā kaʻina hana:
• Ma mua o ka lawe ʻana iā sirolimus,
• Hoʻokumu paha ʻo Sirolimus i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. ʻAʻole ʻike pinepine ʻia nā ʻōuli aʻe, akā inā ʻike ʻoe i kekahi o lākou a i ʻole nā ​​mea i helu ʻia i ka ʻĀINA WAIWAI, e kāhea koke i kāu kauka.

Hiki i ka Sirolimus ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i kahi maʻi a i ʻole maʻi ʻaʻai, ʻo ia hoʻi ka lymphoma (maʻi ʻaʻai o kahi ʻāpana o ka ʻōnaehana pale) a i ʻole ka maʻi ʻaʻai ʻili. I mea e hōʻemi ai i kāu makaʻu o ka maʻi ʻaʻai ʻili, e hoʻolālā e hōʻalo i kahi kūpono ʻole a hoʻolōʻihi ʻia i ka lā a e komo i nā lole pale, nā aniani aniani, a me nā pale pale lā i kāu wā e lapaʻau ai. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: fiva, ʻeha ka ʻāʻī, haʻalulu, urination pinepine a ʻeha paha, a i ʻole nā ​​hōʻailona ʻino ʻē aʻe; ʻeha hou a hoʻololi paha i ka ʻili; sweats po; ʻōhū hāhā i ka ʻāʻī, nā ʻāpana lima, a i ʻole ke auwaha; ka wehewehe kaumaha i wehewehe ʻole ʻia; pilikia hanu; ʻeha ka umauma; nāwaliwali a luhi paha e hele ʻole aku ai; a ʻeha paha, ʻōhū, a i ʻole piha i ka ʻōpū.

Hoʻokumu paha ʻo Sirolimus i nā hopena koʻikoʻi a i ʻole ka make ʻana i nā mea maʻi i loaʻa i ke ake a i ʻole nā ​​ake. ʻAʻole pono e hāʻawi ʻia kēia lāʻau i mea e pale aku ai i ka hōʻole ʻana i ke ake a i ʻole nā ​​transplants māmā.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua e nānā i ka pane o kou kino iā sirolimus.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka sirolimus.

Hoʻohana ʻia ʻo Sirolimus me ka hoʻohui pū me nā lāʻau ʻē aʻe e pale ai i ka hōʻole ʻana i nā transplants kidney. Aia ʻo Sirolimus i ka papa o nā lāʻau i kapa ʻia he immunosuppressants. Hana ia i ka kaohi ʻana i ka ʻōnaehana pale o ke kino.

Hele mai ʻo Sirolimus ma ke ʻano he papa a me kahi hopena (wai) e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā, me ka meaʻai a mau ʻole me ka ʻole o ka meaʻai. E kōkua iā ʻoe e hoʻomanaʻo e lawe i ka sirolimus, e lawe a puni ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā sirolimus e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

E hoʻoponopono paha kāu kauka i kāu mahele lāʻau o sirolimus i kou wā e mālama ai, ʻaʻole ma mua o hoʻokahi manawa i kēlā me kēia 7 a 14 mau lā.

E hoʻomau i ka lawe ʻana i ka sirolimus ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka sirolimus me ke kamaʻilio ʻole ʻana me kāu kauka.

Hoʻolālā paha ka hopena Sirolimus i kahi haze ke hoʻomaʻalili ʻia. Inā kū kēia, e kū ka ʻōmole i ka mahana o ka lumi a hoʻoluliluli mālie a hala ka haze. ʻAʻole ka manaʻo o ka haze i ka hōʻino ʻia o ka lāʻau a palekana ʻole paha e hoʻohana.

E hoʻohana i nā ʻōmole o ka hopena, e hāhai i nā kaʻina hana:

1. E wehe i ka ʻōmole hoʻonā. I ka hoʻohana mua ʻana, hoʻokomo i ka ʻōmole palolo me ka paʻa me ka paʻa i loko o ka ʻōmole a hiki i ke kiko o ka ʻōmole. Mai wehe i ka ʻōmole i hoʻokomo ʻia.
2. No kēlā me kēia hoʻohana, e hoʻokomo pono i kekahi o nā syringes amber, me ka plunger i pahu piha ʻia i loko, i loko o ka puka i loko o ka pahu ea.
3. E huki i ka nui o ka hopena a kāu kauka i kuhikuhi ai ma ka huki ʻana i ka plunger o ka syringe a hiki i ka lalo o ka laina ʻeleʻele o ka plunger me nā māka pololei ma ka syringe. E kū pololei ka ʻōmole. Inā hana ʻia nā huʻa i loko o ka syringe, e ninini i ke syringe i loko o ka ʻōmole a hana hou i kēia ʻanuʻu.
4. E hoʻokau i ka syringe i loko o ke kīʻaha a i ʻole kīʻaha plastic i loaʻa ma kahi o 2 auneke (60 milliliter [1/4 kīʻaha]) o ka wai a i ʻole ka wai ʻalani. Mai hoʻohana i ka wai ʻopa, wai wai huaʻakai, a i ʻole nā ​​wai ʻē aʻe. E hoʻoikaika ikaika no 1 mau minuke a inu koke.
5. Hoʻopiha hou i ke kīʻaha me ka liʻiliʻi he 4 auneke (120 milliliter [1/2 cup]) o ka wai a i ʻole ka wai ʻalani. E hoʻoulu ikaika a inu i ka wai holoi holoi.
6. Hoʻolei o ka syringe i hoʻohana ʻia.

Inā pono ʻoe e halihali i kahi ʻake a piha me ʻoe, kāpili i kahi pāpale ma luna o ka ʻenekini a kau i ka ʻekena i ka hihia hāpai. E hoʻohana i ka lāʻau i loko o ka syringe ma loko o 24 mau hola.

Hoʻohana ʻia ʻo Sirolimus i kekahi manawa e mālama iā psoriasis. E kamaʻilio me kāu kauka e pili ana i nā pilikia e hiki ke hoʻohana i kēia lāʻau no kāu maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana iā sirolimus,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka sirolimus, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka papa sirolimus a i ʻole ka hopena. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei. E ʻōlelo pono i kekahi o kēia mau mea: aminoglycoside antibiotics e like me amikacin, gentamicin, kanamycin, neomycin (Neo-Fradin, Neo-Rx), streptomycin, a me tobramycin (Tobi); amphotericin B (Abelcet, AmBisome, Amphocin, Fungizone); Angiotensin-hoʻololi i ka enzyme (ACE) mea kāohi e like me benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril) ), ramipril (Altace), a me trandolapril (Mavik); nā antifungals e like me clotrimazole (Lotrimin), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), a me voriconazole (Vfend); bromocriptine (Cycloset, Parlodel); cimetidine (Tagamet); cisapride (Propulsid) (ʻaʻole loaʻa ma ka U.S.); clarithromycin (Biaxin); danazol (Danocrine); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin (E.E.S., E-Mycin, Erythrocin); Nā mea hoʻopalekana protease HIV e like me indinavir (Crixivan) a me ritonavir (Norvir, ma Kaletra); kekahi mau lāʻau no ka cholesterol; nā lāʻau no ka hopu ʻana e like me carbamazepine (Tegretol), phenobarbital (Luminal), a me phenytoin (Dilantin); metoclopramide (Reglan); nicardipine (Cardene); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); rifapentine (Priftin); telithromycin (Ketek); troleandomycin (TAO) (ʻaʻole loaʻa ma ka U.S.); a me verapamil (Calan, Covera, Isoptin, Verelan). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• inā ʻoe e lawe nei i ka cyclosporine (Neoral) capsule gelatin palupalu a i ʻole ka hopena, lawe iā lākou i 4 mau hola ma mua o sirolimus.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa iā ʻoe ke kiʻekiʻe o ka kolesterol a i ʻole nā ​​triglycerides a i ʻole nā ​​maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Pono ʻoe e hoʻohana i kahi hana kūpono o ka kaohi hānau ma mua o ka hoʻomaka ʻana e lawe i ka sirolimus, ʻoiai e lawe ana i ka sirolimus, a no 12 mau pule ma hope o ka pau ʻana o ka sirolimus. Inā hāpai ʻoe i ka wā e lawe ana iā sirolimus, e kāhea i kāu kauka.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe iā sirolimus
• ʻaʻohe o nā lāʻau āpau ke kamaʻilio ʻole ʻia me kāu kauka.

Hōʻalo i ka inu ʻana i ka wai wai mālamo i ka lawe ʻana i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Sirolimus i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha ka ʻōpū
• ʻeha poʻo
• kōpaʻa
• pāhoehoe
• nausea
• ʻeha pū

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. ʻAʻole ʻike pinepine ʻia nā ʻōuli aʻe, akā inā ʻike ʻoe i kekahi o lākou a i ʻole nā ​​mea i helu ʻia i ka ʻĀINA WAIWAI, e kāhea koke i kāu kauka.

• kahe koko ʻole ʻana a palapū paha
• ʻūhā
• pehu, ʻulaʻula, māwae, ʻāwīwī ʻili
• hives
• hūwī
• ʻūlili
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana
• ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• hulahula

Hoʻokumu paha ʻo Sirolimus i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama i nā papa i ka mahana o ka lumi a mamao aku mai ka mālamalama, ka nui o ka wela, a me ka makū (ʻaʻole i loko o ka lua. E mālama i ka lāʻau i loko o ka pahu hau, mai ka mālamalama, paʻa paʻa, a hoʻolei i nā lāʻau i hoʻohana ʻole ʻia hoʻokahi mahina ma hope o ka wehe ʻia ʻana o ka ʻōmole. Mai paʻa hau. Inā pono, hiki iā ʻoe ke mālama i nā ʻōmole a 15 mau lā i ka mahana o ka lumi.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Rapamune^®

• Rapamycin