Mifepristone (Mifeprex)

Anter

• Ma mua o ka lawe ʻana i mifepristone,
• Hiki i ka Mifepristone ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hiki ke hana i ke kahe kahe nui a hoʻoweliweli paha i ka wā e hoʻopau ʻia ai kahi hāpai e ka hāpai keiki ʻole a i ʻole ka lāʻau lapaʻau a i ʻole ke kauka. ʻAʻole i ʻike ʻia inā hoʻonui ka mimepristone i ka makaʻu e ʻike ʻoe i ke kahe kaumaha loa. E haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe nā pilikia kahe o ke kahe, anemia (ʻoi aku ma mua o ka helu maʻamau o nā hunaola ʻulaʻula), a i ʻole inā ʻoe e lawe i nā anticoagulants ('ʻoki koko ") e like me aspirin, apixaban (Eliquis), dabigatran (Pradaxa) , dalteparin (Fragmin), edoxaban (Savaysa). enoxaparin (Lovenox), Fondaparinux (Arixtra), heparin, rivaroxaban (Xarelto), a i ʻole warfarin (Coumadin, Jantoven). Inā pēlā, e haʻi paha kāu kauka iā ʻoe mai lawe i ka mifepristone. Inā ʻike ʻoe i ke kahe nui o ke kahe o ke kino, e like me ke kulu ʻana i loko o ʻelua mau pale hoʻomaʻemaʻe piha piha i kēlā me kēia hola no nā hola mau ʻelua, e kelepona koke i kāu kauka a i ʻole e ʻimi i ka mālama olakino olakino

Hiki ke hōʻea i nā maʻi kūpilikiʻi a i ʻole hoʻoweliweli ke ola ke hoʻopau ʻia kahi hāpai ʻana e ka hāʻule ʻole a i ʻole ka lāʻau lapaʻau a i ʻole ka hāpai ʻōpū. Ua make kekahi hapa liʻiliʻi o nā maʻi ma muli o nā maʻi i hoʻomohala ʻia ma hope o ka hoʻohana ʻana i ka mifepristone a me ka misoprostol e hoʻopau ai i kā lākou hāpai keiki. ʻAʻole ʻike ʻia inā mifepristone a me / a i ʻole misoprostol i hoʻokumu i kēia mau maʻi a make paha. Inā hoʻomohala ʻoe i kahi maʻi kūpilikiʻi, ʻaʻole nui paha kāu mau ʻōuli a nui ʻole paha kāu mau ʻōuli. Pono ʻoe e kāhea koke i kāu kauka a i ʻole e loaʻa i ka lāʻau olakino olakino inā ʻike ʻoe i kekahi o nā ʻōuli e hiki mai ana: ke kuni ma mua o 100.4 ° F (38 ° C) i ʻoi aku ma mua o 4 mau hola, ʻehaʻeha a palupalu paha ma ka wahi ma lalo o ka pūhaka haʻalulu, puʻuwai wikiwiki, a maule paha.

Pono ʻoe e kāhea koke i kāu kauka a i ʻole e loaʻa i ka lāʻau olakino olakino inā loaʻa iā ʻoe nā ʻōuli laulā o ka maʻi e like me ka nāwaliwali, nausea, luaʻi, diarrhea, a i ʻole maʻi maʻi no ʻoi aku ma mua o 24 mau hola ma hope o ka lawe ʻana i ka mifepristone inā ʻaʻohe ou kuni a ʻeha paha. i ka wahi ma lalo o kou pūhaka.

Ma muli o nā pilikia o nā pilikia koʻikoʻi, loaʻa wale ka mifepristone ma o kahi papahana i kaupalena ʻia. Ua hoʻonohonoho ʻia kahi papahana ma lalo o ke kāhea ʻia ʻo Mifeprex Risk Evaluation and Mitigation Strategies (REMS) no nā wahine maʻi āpau e kuhikuhi ʻia mifepristone. E hāʻawi aku kāu kauka iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Medication Guide) e heluhelu ma mua o kou hoʻomaka ʻana i ka lāʻau me ka mifepristone. Pono ʻoe e kau inoa i ka ʻaelike ahonui ma mua o ka lawe ʻana i ka mifepristone. E haʻi i kāu kauka inā he mau nīnau kāu e pili ana i ka mālama ʻana me mifepristone a i ʻole inā ʻaʻole hiki iā ʻoe ke hahai i nā alakaʻi i ka ʻaelike a ka mea maʻi. Loaʻa ʻo Mifepristone i nā keʻena lapaʻau, nā keʻena lapaʻau, a me nā haukapila ʻaʻole i hāʻawi ʻia ma o nā hale kūʻai kūʻai liʻiliʻi.

E kamaʻilio me kāu kauka a hoʻoholo i ka mea e kāhea a me ka mea e hana ai inā loaʻa kahi pilikia ma hope o ka lawe ʻana i ka mifepristone. E haʻi i kāu kauka inā ʻaʻole ʻoe e noʻonoʻo e hiki iā ʻoe ke hāhai i kēia hoʻolālā a i ʻole e kiʻi wikiwiki ʻana i ka lāʻau lapaʻau i kahi ulia pōpilikia i nā pule ʻelua i hala ma hope o kou lawe ʻana i ka mifepristone. Lawe i kāu alakaʻi lāʻau me ʻoe inā ʻoe e kipa i kahi keʻena pilikia a i ʻole ʻimi i ka mālama olakino pōpilikia i mea e maopopo ai i nā kauka nāna ʻoe e mālama nei i kāu hāpai maʻi lapaʻau

Mālama i nā manawa āpau me kāu kauka. Pono kēia mau mea i koho ʻia e ʻike pono ua pau kou hāpai ʻana a ʻaʻole ʻoe i hoʻomohala i nā pilikia koʻikoʻi o ka hoʻōla hānau.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka mifepristone.

Hoʻohana ʻia ʻo Mifepristone me ka misoprostol (Cytotec) e hoʻopau ai i ka hāpai mua. ʻO ke kumu o ka hāpai mua ʻana he 70 mau lā a ʻoi iki paha mai kou wā menstrual hope loa. Aia ʻo Mifepristone i kahi papa o nā lāʻau i kapa ʻia he antiprogestational steroid. Hana ia ma ka pale ʻana i ka hana o progesterone, kahi mea i hana ʻia e kou kino e kōkua i ka hoʻomau ʻana i ka hāpai ʻana.

Loaʻa ʻo Mifepristone ma ke ʻano he huahana ʻē aʻe (Korlym), i hoʻohana ʻia e kaohi i ka hyperglycemia (ke kō kiʻekiʻe o ke kō) i nā poʻe me kekahi ʻano o Cushing's Syndrome kahi e hana ai ke kino i ka nui o ka hormone cortisol. Hāʻawi wale kēia monograp i ka ʻike e pili ana i ka mifepristone (Mifeprex), kahi e hoʻohana wale ʻia a i ʻole me ka hoʻohui ʻia me kekahi lāʻau e hoʻopau ai i ka hāpai mua. Inā ʻoe e hoʻohana ana i ka mifepristone e kaohi ai i ka hyperglycemia i hoʻokumu ʻia e Cushing's syndrome, e heluhelu i ka monograph i kapa ʻia ʻo mifepristone (Korlym) i kākau ʻia e pili ana i kēia huahana.

Hele mai ʻo Mifepristone ma ke ʻano he papa e lawe ma ka waha. E lawe ʻoe i hoʻokahi papa o mifepristone i hoʻokahi manawa i ka lā mua. Ma waena o 24 a 48 mau hola ma hope o ka lawe ʻana i ka mifepristone, e hoʻopili ʻoe i ʻehā papa i ka huina o kahi lāʻau ʻē aʻe i kapa ʻia ʻo misoprostol buccally (ma waena o ka gum a me ka pāpālina) ma ke kau ʻana i ʻelua papa i loko o kēlā me kēia ʻeke papalina no 30 mau minuke, a laila e ale ana i ka mea i koe me ka wai a i ʻole kekahi. wai. E ʻike pono aia ʻoe i kahi kūpono ke lawe ʻoe i ka misoprostol ma muli o ka hoʻomaka pinepine ʻana o ke kahe ʻana o ka maʻi puʻupuʻu i loko o 2 a 24 mau hola ma hope o ka lawe ʻana akā hiki ke hoʻomaka i loko o 2 mau hola.ʻO ka holo ʻana o ka maʻi Vaginal a i ʻole ke kiko ʻana mau no 9 a 16 mau lā akā hiki ke mau no 30 mau lā a ʻoi paha. Pono ʻoe e hoʻi i kāu kauka no kahi hōʻike a ultrasound 7 a 14 mau lā ma hope o ka lawe ʻana i ka mifepristone e hōʻoia ua pau ka hāpai a nānā i ka nui o ke kahe. Lawe i mifepristone e like me ke kuhikuhi.

Hoʻohana pū ʻia ʻo Mifepristone i kekahi manawa e hoʻopau i nā hāpai keiki ke hala ʻoi aku ma mua o 70 mau lā mai ka wā menstrual hope loa o ka wahine; ma ke ʻano he contraceptive pilikia ma hope o ka moe kolohe ʻole ʻia ('kakahiaka-ma hope o ka pila'); e mālama i nā tumors o ka lolo, endometriosis (ka ulu ʻana o nā kiko o ka uterus ma waho o ka uterus), a i ʻole fibroids (noncancerous tumors in the uterus); aiʻole e hoʻoulu i ka hana (e kōkua i ka hoʻomaka ʻana o ke kaʻina hanau i ka wahine hāpai). E kamaʻilio me kāu kauka e pili ana i nā pilikia e hiki ke hoʻohana i kēia lāʻau no kou maʻi.

Ma mua o ka lawe ʻana i mifepristone,

• e haʻi i kāu kauka inā ʻaʻa ʻoe i ka mifepristone (hives, pehu, ʻili, pehu o ka maka, maka, waha, ʻāʻī, lima; paʻakikī i ka hanu ʻana a me ka ale ʻana paha); misoprostol (Cytotec, ma Arthrotec); nā prostaglandins e like me alprostadil (Caverject, Edex, Muse, a me nā mea ʻē aʻe), carboprost tromethamine (Hemabate), dinoprostone (Cervidil, Prepidil, Prostin E2), epoprostenol (Flolan, Veletri), latanoprost (X kagamitan), treprostinil (Orenitram, Remodulin ); nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i loko o ka papa mimepristone. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā e lawe nei ʻoe i nā corticosteroids e like me beclomethasone (Beconase, QNASL, QVAR), betamethasone (Celestone), budesonide (Entocort, Pulmicort, Uceris), cortisone, dexamethasone, fludrocortisone, flunisolide (Aerospan HFA), flvaisolide (Aerospan HFA) , Veramyst, kekahi poʻe ʻē aʻe), hydrocortisone (Cortef, Solu-Cortef, U-Cort, a me nā mea ʻē aʻe), methylprednisolone (Medrol, Depo-Medrol), prednisolone (Omnipred, Prelone, a me nā mea ʻē aʻe), prednisone (Rayos), a me triamcinolone (Kenalog, a me nā mea ʻē aʻe. ). E haʻi paha kāu kauka iā ʻoe mai lawe i ka mifepristone.
• e haʻi i kāu kauka i nā lāʻau lapaʻau ʻē aʻe a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei. E hoʻomaopopo pono i nā lāʻau i helu ʻia i ka ʻĀINA WAIWAI nui a me kekahi o nā mea penei: benzodiazepines e like me alprazolam (Xanax), diazepam (Diastat, Valium), midazolam, a i ʻole triazolam (Halcion); buspirone; nā poloka kalipuna e like me amlodipine (Norvasc), diltiazem (Cardizem, Cartia, Diltzac, a me nā mea ʻē aʻe), felodipine, nifedipine (Adalat, Afeditab CR, Procardia), nisoldipine (Sular), a i ʻole verapamil (Calan, Verelan, ma Tarka); carbamazepine (Equetro, Tegretol, Teril, nā mea ʻē aʻe); chlorpheniramine (antihistamine i ka huā a me nā huahana anu); nā lāʻau hoʻohaʻahaʻa kolesterol (statins) e like me atorvastatin (Lipitor, ma Caduet), lovastatin (Altoprev, ma Advicor), a i ʻole simvastatin (Simcor, Zocor, i Vytorin); clarithromycin (Biaxin, i Prevpac); cyclosporine (Gengraf, Neoral, Sandimmune); erythromycin (E.E.S., Erythrocin, nā mea ʻē aʻe); haloperidol; huluhulu Nā mea hoʻopalekana protease HIV e like me indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ma Kaletra, a me nā mea ʻē aʻe), a i ʻole saquinavir (Invirase); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); methadone (Dolophine, Methadose); nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); pimozide (Orap); propranolol (Hemangeol, Inderal, Innopran); quinidine (i Nuedexta); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); rifabutin (Mycobutin); tacrolimus (Astagraf, Prograf, Protopic, nā mea ʻē aʻe); tamoxifen (Soltamox); trazodone; aiʻole vincristine (Marqibo Kit). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa iā ʻoe i kahi hāpai hāpai ectopic ('tubal hāpai' a i ʻole hāpai ma waho o ka uterus), adrenal fail (nā pilikia me kāu adrenal glands), a i ʻole porphyria (kahi maʻi koko i hoʻoili ʻia e hiki ai i nā pilikia o ka ʻili a me ka ʻenemi. ). E haʻi paha kāu kauka iā ʻoe mai lawe i ka mifepristone. Eia kekahi, e haʻi i kāu kauka inā loaʻa iā ʻoe kahi mea intrauterine (IUD) i hoʻokomo ʻia. Pono e hemo ia ma mua o kou lawe i ka mifepristone.
• pono ʻoe e ʻike he hiki paha i ka mifepristone ke hoʻopau ʻole i kou hāpai ʻana. E hōʻoia kāu kauka e ʻike pono ua pau kou hāpai ʻana i kou wā i hoʻi ai i kāu manawa e ukali ai ma hope o kou lawe ʻana i ka mifepristone. Inā hāpai ʻoe ma hope o ka lawe ʻana i ka mifepristone, aia kahi manawa e hānau ʻia ai kāu pēpē me nā kīnā hānau. Inā ʻaʻole i pau iki kāu hāpai ʻana, e kūkākūkā kāu kauka i nā koho ʻē aʻe e noʻonoʻo ai. Hiki iā ʻoe ke koho e kali, e lawe i kahi lāʻau o misoprostol a i ʻole e ʻoki ʻia e hoʻopau i ka hāpai ʻana. Inā ʻoe e lawe i kahi lāʻau hou o misoprostol, pono ʻoe e kipa hou aku me kāu kauka i 7 mau lā ma hope o kēlā lāʻau e hōʻoia ua pau kou hāpai ʻana.

• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū.

• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho ua kiʻi ʻoe i ka nifepristone.
• pono ʻoe e ʻike ma hope o ka pau ʻana o kahi hāpai me mifepristone, hiki iā ʻoe ke hāpai hou i ka manawa koke, ʻoiai ma mua o ka hoʻi ʻana o kou wā. Inā ʻaʻole ʻoe makemake e hāpai hou, pono ʻoe e hoʻomaka i ka hoʻohana ʻana i ka kaohi hānau ke pau kēia hāpai ʻana a ma mua paha o kou hoʻomaka hou ʻana i ka moekolohe.

Mai lawe iā mifepristone me ka wai momona. E kamaʻilio me kāu kauka e pili ana i ka inu ʻana i ka wai huaʻalani ma hope o ka lawe ʻana i kēia lāʻau.

E lawe wale ʻoe iā mifepristone i ke keʻena o kāu kauka a i ʻole ke keʻena lapaʻau, no laila ʻaʻole ʻoe e hopohopo no ka hoʻopoina ʻana e lawe i kahi lāʻau ma ka home.

Hiki i ka Mifepristone ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• kahe koko a i ʻole ke kiko ʻana
• ʻūlū
• ʻeha pelvis
• ʻā, hemo, a hoʻokuʻu paha
• ʻeha poʻo

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o nā ʻōuli i ʻōlelo ʻia ma ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka.

Hoʻokumu paha ʻo Mifepristone i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama kāu kauka i ka lāʻau i loko o kāna keʻena.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻūpā
• maule ana
• ʻike hihi
• nausea
• luhi
• nāwaliwali
• pokole o ka hanu
• puʻuwai wikiwiki

Pono ʻoe e kiʻi mifepristone mai kahi kauka i hōʻoia ʻia a hoʻohana i kēia lāʻau wale nō ma lalo o ka mālama a ke kauka. ʻAʻole pono ʻoe e kūʻai i ka mifepristone mai nā kumuwaiwai ʻē aʻe, e like me ka Pūnaewele, no ka mea e pale aku ʻoe i nā palekana nui e pale ai i kou olakino.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Mifeprex^®

• RU-486