17-hydroxycorticosteroids mimi hoʻāʻo

ʻO ka 17-hydroxycorticosteroids (17-OHCS) e ana i ka pae o ka 17-OHCS i ka mimi.

Pono kahi laʻana mimi he 24 mau hola. Pono ʻoe e hōʻiliʻili i kou mimi ma kahi o 24 mau hola. E haʻi aku kāu mea mālama ola iā ʻoe pehea e hana ai i kēia. E hahai pololei i nā ʻōkuhi.

E aʻo ka mea hāʻawi iā ʻoe, inā pono, e hōʻoki i nā lāʻau e hoʻopilikia paha i ka hōʻike. Pākuʻi ʻia kēia mau mea:

• Nā lāʻau kaohi hānau i loaʻa ka estrogen
• ʻO kekahi antibiotic
• ʻO Glucocorticoids

Hoʻopili wale ka hōʻike i ka urination maʻamau wale nō. ʻAʻohe pilikia.

17-OHCS kahi huahana i hoʻokumu ʻia i ka wā e wāwahi ai ke akepaʻa a me nā kino o ke kino i ka steroid hormone cortisol.

Hiki i kēia hōʻoia ke kōkua i ka hoʻoholo inā hana nui ke kino i ka nui o ka cortisol. Hiki ke hoʻohana ʻia ka hōʻike e hōʻike ai i ka maʻi Cushing. He maʻi kēia e kū ana ke loaʻa i ke kino ka pae kiʻekiʻe mau o ka cortisol.

Hana pinepine ʻia ka mimi a me ka creatinine mimi me ka hoʻāʻo 17-OHCS i ka manawa like. Kōkua kēia i ka mea hāʻawi e wehewehe i ka hoʻāʻo.

ʻAʻole hana pinepine ʻia kēia hōʻike i kēia manawa. ʻO ka hōʻike mimi kortisol manuahi kahi hōʻike loiloi ʻoi aku ka maikaʻi no ka maʻi Cushing.

Nā waiwai maʻamau:

• Kāne: 3 a 9 mg / 24 mau hola (8.3 a 25 µmol / 24 mau hola)
• Wahine: 2 a 8 mg / 24 mau hola (5.5 a 22 µmol / 24 mau hola)

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.

E hōʻike paha kahi kiʻekiʻe ma mua o ka pae maʻamau o 17-OHCS:

• ʻO kahi ʻano o Cushing Syndrome i hoʻokumu ʻia e kahi tumo i ka adrenal gland e hana i ka cortisol
• Kaumaha
• Hoʻolālā Hydrocortisone
• Kaʻai pono ʻole
• Ka momona
• Hapai keiki
• ʻO kahi kumu hormonal o ke kiʻekiʻe kiʻekiʻe o ke koko
• Kaumaha nui o ke kino a me ke kaumaha paha
• Tumor i ka pituitary gland a i ʻole nā ​​wahi ʻē aʻe o ke kino e hoʻokuʻu i kahi hōmona i kapa ʻia he adrenocorticotropic hormone (ACTH)

Hōʻike paha kahi haʻahaʻa ma lalo o ka pae maʻamau o 17-OHCS:

• ʻAʻole hana nui nā adrenal adrenal o kā lākou mau hormones
• ʻAʻole hiki i ka pituitary gland ke hana lawa i kāna mau hormona
• Ka nele o ka enzyme hoʻoilina
• ʻO ke kahakaha ma mua e wehe i ka momona adrenal

Hiki i ka mimiki ma mua o 3 liters o ka lā (polyuria) ke hana i ka hopena o ka hoʻāʻo kiʻekiʻe ʻoiai ʻo normal ka hana ʻana o cortisol.

ʻAʻohe pilikia me kēia hōʻike.

17-OH corticosteroids; 17-OHCS

Chernecky CC, Berger BJ. 17-hydroxycorticosteroids (17-OHCS) - mimi he 24 mau hola. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 659-660.

ʻO Juszczak A, Morris DG, Grossman AB, Nieman LK. ʻO Cushing's syndrome. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 13.