ʻO Chorionic villus hāpana

ʻO Chorionic villus sampling (CVS) kahi hōʻaʻo e hōʻoia ʻia e kekahi mau wahine hāpai i kā lākou pēpē no nā pilikia kūpuna.

Hiki ke hana i ka CVS ma o ka cervix (transcervical) a i ʻole ma o ka ʻōpū (transabdominal). ʻOi aku ke kiʻekiʻe o nā helu miscarriage ke hana ʻia ka hoʻokolohua ma o ka cervix.

Hana ʻia ke kaʻina transcervical e ka hoʻokomo ʻana i kahi ʻōmole palapū lahilahi ma o ka ʻōpū a me ka cervix e kiʻi i ka placenta. Hoʻohana kāu mea mālama ola i nā kiʻi ultrasound e kōkua i ke alakaʻi ʻana i ka paipu i kahi ʻoi loa no ka laʻana. Lawe ʻia kahi hiʻohiʻona liʻiliʻi o ka villus chorionic (placental).

Hana ʻia ke kaʻina transabdominal e ka hoʻokomo ʻana i kahi nila ma o ka ʻōpū a me ka kōpū a i loko o ka placenta. Hoʻohana ʻia ʻo Ultrasound e kōkua i ke alakaʻi ʻana i ka nila, a huki ʻia kahi liʻiliʻi o nā mea i loko o ke ʻākiʻako.

Hoʻokomo ʻia ka laʻana i loko o kahi pā a loiloi ʻia i kahi lab. Loaʻa nā hopena hōʻike ma kahi o 2 mau pule.

E wehewehe kāu mea lawelawe i ke kaʻina hana, nā pilikia, a me nā kaʻina hana ʻē aʻe e like me amniocentesis.

E noi ʻia ʻoe e kau inoa i kahi palapala ʻae ma mua o kēia kaʻina hana. Nonoi ʻia ʻoe e ʻaʻahu i ke kapa komo i ka haukapila.

I ke kakahiaka o ke kaʻina hana, noi ʻia ʻoe e inu i nā wai a hōʻole i ka mimī. Hoʻopiha ka hana ʻana i kāu pēpē, e kōkua ai i kāu mea lawelawe e ʻike i kahi e alakaʻi pono ai i ka nila.

E haʻi aku i kāu mea hāʻawi inā maʻi ʻoe i ka iodine a i ʻole ka ʻāpala, a i ʻole he maʻi ʻē aʻe kāu.

ʻAʻole ʻeha ka ultrasound. Hoʻopili ʻia kahi gel maopopo, wai-hoʻokumu i kou ʻili e kōkua i ka lawe ʻana o nā nalu kani. ʻO kahi ʻimi lima paʻa lima i kapa ʻia transducer a laila neʻe ʻia ma luna o kou ʻōpū. Hoʻohui, hiki i kāu mea lawelawe ke kau i ka pihi ma kou ʻōpū e ʻike i ke kūlana o kou kōpū.

ʻIke ke anu i ka mua a hoʻonāukiuki paha i kou ʻili inā ʻaʻole holoi ʻia ma hope o ke kaʻina hana.

Wahi a kekahi mau wahine ua like ke ʻano o ka helehelena me ka hoʻāʻo Pap me kahi ʻoluʻolu ʻole a me ke ʻano o ke kaomi. Aia paha he wahi liʻiliʻi o ke kahe o ke kahe ma hope o ke kaʻina hana.

Hiki i kahi kaukōʻau hānau ke hana i kēia kaʻina hana ma kahi o 5 mau minuke, ma hope o ka hoʻomākaukau.

Hoʻohana ʻia ka hoʻokolohua e ʻike ai i nā ʻano maʻi genetika i kāu pēpē i hānau ʻole ʻia. He pololei loa ia, a hiki ke hana ʻia i kakahiaka nui i ka hāpai ʻana.

Hiki i nā pilikia genetic ke kū i kekahi hāpai keiki. Eia nō naʻe, hoʻonui nā mea aʻe i ka makaʻu:

• He makuahine makua
• Nā hānau hānau i hala me nā pilikia kūpuna
• ʻO ka mōʻaukala ʻohana o nā maʻi kūlohelohe

Paipai ʻia ka ʻōlelo aʻoaʻo genetic ma mua o ke kaʻina hana. E ʻae kēia iā ʻoe e hana i kahi hoʻoholo wikiwiki ʻole e pili ana i nā koho no ka hōʻoia prenatal.

Hiki ke hana ʻo CVS ma mua o ka hāpai ʻana ma mua o ka amniocentesis, pinepine ma kahi o 10 a 12 mau pule.

ʻAʻole ʻike ʻo CVS:

• Nā kīnā neural tube (pili kēia i ka koluma spinal a i ʻole ka lolo)
• Rh incompatibility (hiki mai kēia i ka wā hāpai o ka wahine hāpai Rh-maikaʻi ʻole ke koko a me kāna pēpē i hānau ʻia he Rh-maikaʻi ke koko)
• Hewa hānau
• Nā pilikia e pili ana i ka hana o ka lolo, e like me ka autism a me ke kīnā ʻole o ka ʻike
  
  

ʻO kahi hopena maʻamau, ʻaʻohe hōʻailona o nā kīnā genetika i ka pēpē e ulu ana. ʻOiai pololei loa nā hopena hōʻike, ʻaʻohe hōʻike 100% pololei i ka hoʻāʻo ʻana no nā pilikia kūpuna i ka hāpai ʻana.

Hiki i kēia hoʻāʻo ke kōkua i ka huki ʻana i nā maʻi genetika he haneli. Nā hualoaʻa kūpono ʻole paha ma muli o nā ʻano kūpuna like ʻole, e like me:

• Down syndrome
• Hemoglobinopathies
• Maʻi ʻo Tay-Sachs

E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike. E noi i kāu mea hāʻawi:

• Pehea e mālama ʻia ai ke ʻano a i ʻole kīnā paha i ka wā a ma hope paha o ka hāpai ʻana
• He aha nā mea kūikawā e pono ai kāu keiki ma hope o ka hānau ʻana
• He aha nā koho ʻē aʻe āu e pili ana i ka mālama ʻana a hoʻopau ʻana i kāu hāpai ʻana

ʻOi aku ka kiʻekiʻe o nā makaʻu o CVS ma mua o ka amniocentesis.

ʻO nā pilikia i hiki ke hoʻopili ʻia:

• Kahena
• Maʻi kīnā
• Hewa (a i 1 i 100 mau wahine)
• Rh incompatibility i ka makuahine
• Rupture o nā membrane e hiki ai ke alakaʻi i ka hāʻule ʻole

Inā maikaʻi ʻole kou koko Rh, hiki iā ʻoe ke loaʻa i kahi lāʻau i kapa ʻia ʻo Rho (D) immune globulin (RhoGAM a me nā mana ʻē aʻe) e pale aku i ka pili ʻole o Rh.

E loaʻa iā ʻoe kahi ultrasound ukali 2 a 4 mau lā ma hope o ke kaʻina hana e hōʻoia i ka holo maʻamau o kou hāpai ʻana.

CVS; Hāpai - CVS; ʻLelo aʻoaʻo genetic - CVS

• ʻO Chorionic villus hāpana
• Chorionic villus hāpana - series

ʻO Cheng EY ʻImi Prenatal. I: Gleason CA, Juul SE, eds. Nā maʻi o Avery o ke keiki hānau. 10 o ka lā. Piladelapia, PA: Elsevier; 2018: chap 18.

ʻO Driscoll DA, Simpson JL, Holzgreve W, Otano L. Ke kānana genetic a me ka ʻike genen prenatal. I: Gabbe SG, Niebyl JR, Simpson JL, et al, eds. Nā Obstetrics: Nā Pregnancies Maʻamau a me nā pilikia. ʻEpekema 7 Piladelapia, PA: Elsevier; 2017: chap 10.

ʻO Wapner RJ, Dugoff L. Palapala Prental diagnosis of congenital disorders. I: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, eds. ʻO Medicine a Maternal-Fetal a Creasy a me Resnik: Nā Manaʻo a me ka Hoʻomeheu. 8th ed. Piladelapia, PA: Elsevier; 2019: chap 32.