ʻO ka loiloi phenylalanine serum

ʻO ka kānana phenylalanine kānana kahi hōʻike koko e nānā i nā hōʻailona o ka maʻi phenylketonuria (PKU). Kuhi ka hōʻike i nā kiʻekiʻe kiʻekiʻe o kahi amino acid i kapa ʻia ʻo phenylalanine.

Hana pinepine ʻia ka hōʻoia ma ke ʻano he mahele o nā hōʻike loiloi maʻamau ma mua o ka haʻalele ʻana o kahi keiki hānau hou i ka haukapila. Inā hānau ʻole ʻia ke keiki i ka haukapila, pono e hōʻike i ka hōʻike ma 48 a 72 mau hola o ke ola.

ʻO kahi ʻāpana o ka ʻili o ke pēpē, ʻo ka pinepine o ka kuʻekuʻe wāwae, hoʻomaʻemaʻe ʻia me ka mea pepehi mikomiko a kuʻi ʻia me ka nila nui a i ʻole ka lancet. Hoʻokomo ʻia ʻekolu mau kulu koko i 3 mau puni hōʻike ʻokoʻa ma kahi ʻāpana o ka pepa. Hiki ke hoʻopili ʻia ka pulupulu a i ʻole ke kāʻei i ka pūnaewele puncture inā ke kahe mau nei ia ma hope o ka lawe ʻia ʻana o nā kulu koko.

Lawe ʻia ka pepa hoʻāʻo i ke keʻena hoʻokolohua, kahi i hui ʻia me kahi ʻano bacteria e pono ai ka phenylalanine e ulu. Hoʻohui ʻia kekahi mea ʻē aʻe i ālai i ka phenylalanine mai ka hopena ʻana me kekahi mea ʻē aʻe.

ʻO nā hoʻokolohua kānana hānau hou kahi ʻatikala pili.

No ke kōkua i ka hoʻomākaukau ʻana i kāu pēpē no ka hoʻāʻo, e ʻike i ka hoʻokolohua pēpē a i ʻole ka hoʻomākaukau hana (hānau i 1 makahiki).

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi mau pēpē i ka ʻeha kaulike, ʻoiai he prick a i ʻole nā ​​mea ʻū. Ma hope, aia paha kekahi ʻōkā. Hāʻawi ʻia nā pēpē i kahi liʻiliʻi o ke kō kō, i hōʻike ʻia e hōʻemi i ka ʻehaʻeha e pili ana i ka ʻili ʻana o ka ʻili.

Hana ʻia kēia hōʻike e nānā i nā pēpē no PKU, kahi ʻano laha ʻole e hana ʻia ke nele ke kino i kahi mea e pono ai e wāwahi i ka amino acid phenylalanine.

Inā ʻaʻole i ʻike ʻia ʻo PKU i ka wanaʻao, e hoʻonui ka pae phenylalanine i ka pēpē i ke kīnā ʻole o ka ʻike. Ke ʻike wawe ʻia, hiki i nā loli i ka papaʻai ke pale i nā hopena ʻino o PKU.

ʻO ka hopena hōʻike maʻamau ka manaʻo o nā pae phenylalanine maʻamau a ʻaʻohe PKU o ke keiki.

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o nā hopena hōʻike o kāu pēpē.

Inā kūpono ʻole nā ​​hopena hōʻike kānana, he hiki paha iā PKU. E hōʻaʻo hou ʻia inā kiʻekiʻe nā pae phenylalanine i ke koko o kāu pēpē.

ʻOi aku ka makaʻu o ke kaomi ʻana i ke koko, akā hoʻopili pū me:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)
• Nā punctures he nui e ʻimi i nā uaua

Phenylalanine - hoʻāʻo koko; PKU - phenylalanine

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Pasquali M, Longo N. Nānā hou a me nā hewa o loko o ka metabolism. I: Rifai N, ed. ʻO Tietz Textbook of Clinical Chemistry a me nā Molecular Diagnostics. ʻElua huaʻōlelo St Louis, MO: Elsevier; 2018: chap 70.

Zinn AB. Nā hewa i loko o ka ʻōnaehana. I: Martin RJ, Fanaroff AA, Walsh MC, hua. ʻO Fanaroff lāua ʻo Martin's Neonatal-Perinatal Medicine. 10 o ka lā. Piladelapia, PA: Elsevier Saunders; 2015: chap 99.